Page last updated: 2024-08-23

cl 64855 and Trypanosomiasis, African

cl 64855 has been researched along with Trypanosomiasis, African in 17 studies

Research

Studies (17)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's5 (29.41)18.2507
2000's11 (64.71)29.6817
2010's1 (5.88)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Baliani, A; Barrett, MP; Brun, R; Bueno, GJ; Gilbert, IH; Stewart, ML; Yardley, V1
Brun, R; Jędrysiak, R; Kaiser, M; Suwiński, J; Torreele, E; Trunz, BB; Tweats, D1
Burri, C; Büscher, P; Gastellu-Etchegorry, M; Jannin, J; Legros, D; Ollivier, G; Paquet, C1
Bouteille, B; Dumas, M2
Bourdon, L; Bouteille, B; Buguet, A; Chevrier, C; Darsaud, A; Dumas, M1
Boda, C; Bouteille, B; Chauviere, G; Couquet, C; Dumas, M; Dumet, H; Enanga, B; Houin, G; Labrousse, F; Perie, J; Saivin, S1
Bisser, S; Bouteille, B; Chauvière, G; de Albuquerque, C; Dumas, M; Marie-Daragon, A; Périé, J; Rouillard, MC1
Bouteille, B; Chauvière, G; Dardé, ML; de Albuquerque, C; Dumas, M; Enanga, B; Marie-Daragon, A; Périé, J; Vallat, JM1
Chauvière, G; Jennings, FW; Murray, M; Viode, C1
Bouteille, B; Chauvière, G; Dumas, M; Enanga, B; Keita, M1
Boudra, H; Bouteille, B; Chauvière, G; Dumas, M; Enanga, B; Houin, G; Labat, C1
Barrett, MP; Chauvière, G; Fairlamb, AH; Perié, J; Rousseau, B1
Boudra, H; Bouteille, B; Chauvière, G; Debrauwer, L; Dubreuil, G; Dumas, M; Enanga, B; Houin, G; Labat, C; Ndong, JM; Périé, J1
Barrett, MP; Denise, H1
Burri, C; Keiser, J; Stich, A1
Dumas, M1

Reviews

4 review(s) available for cl 64855 and Trypanosomiasis, African

ArticleYear
Treatment of human African trypanosomiasis--present situation and needs for research and development.
    The Lancet. Infectious diseases, 2002, Volume: 2, Issue:7

    Topics: Africa South of the Sahara; Animals; Benzamidines; Drug Therapy, Combination; Eflornithine; Humans; Melarsoprol; Nifurtimox; Thiadiazoles; Trypanocidal Agents; Trypanosoma brucei gambiense; Trypanosoma brucei rhodesiense; Trypanosomiasis, African

2002
[Human African trypanosomiasis: present and future treatment ].
    Bulletin de la Societe de pathologie exotique (1990), 2002, Volume: 95, Issue:5

    Topics: Adenosylmethionine Decarboxylase; Blood-Brain Barrier; Drug Costs; Drug Evaluation, Preclinical; Drug Industry; Forecasting; Global Health; Health Policy; Humans; Myristic Acid; Nitroimidazoles; Thiadiazoles; Trypanocidal Agents; Trypanosomiasis, African; Vaccination

2002
Uptake and mode of action of drugs used against sleeping sickness.
    Biochemical pharmacology, 2001, Jan-01, Volume: 61, Issue:1

    Topics: Animals; Biological Transport; Drug Approval; Drug Design; Drug Resistance; Humans; Thiadiazoles; Trypanocidal Agents; Trypanosoma brucei brucei; Trypanosomiasis, African

2001
[Sleeping sickness, a reemerging sickness].
    Bulletin de l'Academie nationale de medecine, 2000, Volume: 184, Issue:9

    Topics: Africa; Animals; Communicable Diseases, Emerging; Disease Reservoirs; Humans; Mass Screening; Melarsoprol; Population Surveillance; Protozoan Vaccines; Thiadiazoles; Trypanocidal Agents; Trypanosomiasis, African; Vaccination

2000

Other Studies

13 other study(ies) available for cl 64855 and Trypanosomiasis, African

ArticleYear
Design and synthesis of a series of melamine-based nitroheterocycles with activity against Trypanosomatid parasites.
    Journal of medicinal chemistry, 2005, Aug-25, Volume: 48, Issue:17

    Topics: Animals; Cell Line; Female; Furaldehyde; Hydrazones; Leishmania donovani; Mice; Nitrofurans; Nucleoside Transport Proteins; Rats; Thiophenes; Triazines; Trypanocidal Agents; Trypanosoma brucei brucei; Trypanosoma brucei rhodesiense; Trypanosoma cruzi; Trypanosomiasis, African

2005
1-Aryl-4-nitro-1H-imidazoles, a new promising series for the treatment of human African trypanosomiasis.
    European journal of medicinal chemistry, 2011, Volume: 46, Issue:5

    Topics: Animals; Antiprotozoal Agents; Cell Survival; Disease Models, Animal; Dose-Response Relationship, Drug; Female; Humans; Leukocytes, Mononuclear; Mice; Molecular Structure; Mutagenicity Tests; Nitroimidazoles; Oxidation-Reduction; Rats; Rats, Sprague-Dawley; Structure-Activity Relationship; Trypanosomiasis, African

2011
Megazol combined with suramin improves a new diagnosis index of the early meningo-encephalitic phase of experimental African trypanosomiasis.
    Tropical medicine & international health : TM & IH, 2004, Volume: 9, Issue:1

    Topics: Anemia; Animals; Body Weight; Drug Therapy, Combination; Eating; Hematocrit; Male; Meningoencephalitis; Parasitemia; Rats; Rats, Sprague-Dawley; Suramin; Thiadiazoles; Trypanocidal Agents; Trypanosoma brucei brucei; Trypanosomiasis, African

2004
Plasma kinetics and efficacy of oral megazol treatment in Trypanosoma brucei brucei-infected sheep.
    Veterinary parasitology, 2004, May-26, Volume: 121, Issue:3-4

    Topics: Administration, Oral; Animals; Antiprotozoal Agents; Area Under Curve; Body Temperature; Body Weight; Cerebrospinal Fluid; Female; Half-Life; Milk; Parasitemia; Sheep; Sheep Diseases; Thiadiazoles; Trypanosoma brucei brucei; Trypanosomiasis, African

2004
[An efficacy trial on Trypanosoma brucei brucei of molecules permeating the blood-brain barrier and of megazol].
    Bulletin de la Societe de pathologie exotique (1990), 1994, Volume: 87, Issue:5

    Topics: Africa South of the Sahara; Animals; Blood-Brain Barrier; Culture Media; Disease Models, Animal; Female; Free Radicals; Humans; Mice; Reactive Oxygen Species; Thiadiazoles; Trypanocidal Agents; Trypanosoma brucei brucei; Trypanosomiasis, African; World Health Organization

1994
Effect of megazol on Trypanosoma brucei brucei acute and subacute infections in Swiss mice.
    Acta tropica, 1995, Volume: 60, Issue:2

    Topics: Animals; Female; Mice; Thiadiazoles; Trypanocidal Agents; Trypanosoma brucei brucei; Trypanosomiasis, African

1995
Topical chemotherapy for experimental African trypanosomiasis with cerebral involvement: the use of melarsoprol combined with the 5-nitroimidazole, megazol.
    Tropical medicine & international health : TM & IH, 1996, Volume: 1, Issue:3

    Topics: Administration, Topical; Animals; Brain Diseases; Dimethyl Sulfoxide; Drug Therapy, Combination; Female; Gels; Melarsoprol; Mice; Mice, Inbred Strains; Propylene Glycol; Propylene Glycols; Thiadiazoles; Trypanocidal Agents; Trypanosomiasis, African

1996
Megazol combined with suramin: a chemotherapy regimen which reversed the CNS pathology in a model of human African trypanosomiasis in mice.
    Tropical medicine & international health : TM & IH, 1998, Volume: 3, Issue:9

    Topics: Animals; Body Weight; Central Nervous System Diseases; Disease Models, Animal; Drug Evaluation, Preclinical; Drug Therapy, Combination; Female; Humans; Immunohistochemistry; Mice; Recurrence; Suramin; Thiadiazoles; Time Factors; Trypanocidal Agents; Trypanosomiasis, African

1998
Pharmacokinetics, metabolism and excretion of megazol, a new potent trypanocidal drug in animals.
    Arzneimittel-Forschung, 1999, Volume: 49, Issue:5

    Topics: Administration, Oral; Animals; Feces; Female; Injections, Intraperitoneal; Mice; Rats; Thiadiazoles; Trypanocidal Agents; Trypanosoma brucei brucei; Trypanosomiasis, African

1999
Uptake of the nitroimidazole drug megazol by African trypanosomes.
    Biochemical pharmacology, 2000, Mar-15, Volume: 59, Issue:6

    Topics: Africa; Animals; Biological Transport; Drug Interactions; Drug Resistance; Nitroimidazoles; Nucleosides; Receptors, Purinergic P2; Temperature; Thiadiazoles; Time Factors; Trypanocidal Agents; Trypanosoma brucei brucei; Trypanosomiasis, African

2000
Pharmacokinetics, metabolism and excretion of megazol in a Trypanosoma brucei gambiense primate model of human African trypanosomiasis. Preliminary study.
    Arzneimittel-Forschung, 2000, Volume: 50, Issue:2

    Topics: Animals; Area Under Curve; Blood-Brain Barrier; Chlorocebus aethiops; Chromatography, High Pressure Liquid; Feces; Female; Half-Life; Male; Thiadiazoles; Trypanocidal Agents; Trypanosoma brucei gambiense; Trypanosomiasis, African

2000
New drugs for the treatment of human African trypanosomiasis: research and development.
    Trends in parasitology, 2001, Volume: 17, Issue:1

    Topics: Animals; Drug Combinations; Glutathione; Humans; Spermidine; Thiadiazoles; Trypanocidal Agents; Trypanosoma; Trypanosoma brucei rhodesiense; Trypanosomiasis, African

2001
Treatment of human African trypanosomiasis.
    Bulletin of the World Health Organization, 2000, Volume: 78, Issue:12

    Topics: Acetanilides; Africa; Humans; Melarsoprol; Nitroimidazoles; Pentamidine; Suramin; Thiadiazoles; Trypanocidal Agents; Trypanosomiasis, African

2000