cl 387785 has been researched along with Polycystic Kidney, Autosomal Recessive in 1 studies
CL 387785: structure in first source
N-{4-[(3-bromophenyl)amino]quinazolin-6-yl}but-2-ynamide : A member of the class of quinazolines that is 4,6-diaminoquinazoine in which the one of the hydrogens attached to the amino group at position 4 has been replaced by a m-bromophenyl group while one of the hydrogens attached to the amino group at position 6 has been replaced by a but-2-ynoyl group.
Polycystic Kidney, Autosomal Recessive: A genetic disorder with autosomal recessive inheritance, characterized by multiple CYSTS in both KIDNEYS and associated LIVER lesions. Serious manifestations are usually present at BIRTH with high PERINATAL MORTALITY.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Contrary to other murine models of ARPKD, overexpression and apical mislocalization of EGFR were not detected in the PCK rats." | 1.32 | Epidermal growth factor receptor tyrosine kinase inhibition is not protective in PCK rats. ( Avner, ED; Frost, P; Harris, PC; Qian, Q; Sweeney, WE; Torres, VE; Wang, X, 2004) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (100.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Torres, VE | 1 |
| Sweeney, WE | 1 |
| Wang, X | 1 |
| Qian, Q | 1 |
| Harris, PC | 1 |
| Frost, P | 1 |
| Avner, ED | 1 |
1 other study available for cl 387785 and Polycystic Kidney, Autosomal Recessive
| Article | Year |
|---|---|
Epidermal growth factor receptor tyrosine kinase inhibition is not protective in PCK rats.
Topics: Aminoquinolines; Aniline Compounds; Animals; Cyclic AMP; Disease Models, Animal; ErbB Receptors; Fem | 2004 |