Page last updated: 2024-10-25

cl 387785 and Neoplasms

cl 387785 has been researched along with Neoplasms in 2 studies

CL 387785: structure in first source
N-{4-[(3-bromophenyl)amino]quinazolin-6-yl}but-2-ynamide : A member of the class of quinazolines that is 4,6-diaminoquinazoine in which the one of the hydrogens attached to the amino group at position 4 has been replaced by a m-bromophenyl group while one of the hydrogens attached to the amino group at position 6 has been replaced by a but-2-ynoyl group.

Neoplasms: New abnormal growth of tissue. Malignant neoplasms show a greater degree of anaplasia and have the properties of invasion and metastasis, compared to benign neoplasms.

Research Excerpts

ExcerptRelevanceReference
"Genetically defined cancer subsets, irrespective of tissue type, predict response to kinase inhibitors, and provide an important preclinical model to guide early clinical applications of novel targeted inhibitors."1.34Identification of genotype-correlated sensitivity to selective kinase inhibitors by using high-throughput tumor cell line profiling. ( Archibald, H; Dowell, L; Drew, L; Erlander, MG; Gray, NS; Greninger, P; Haber, DA; Hanke, JH; Iafrate, AJ; Lamb, J; Lee, D; Ma, XJ; Maheswaran, S; McDermott, U; Montagut, C; Njauw, CN; Raudales, R; Rothenberg, SM; Settleman, J; Sharma, SV; Sordella, R; Supko, JG; Tam, A; Tsao, H; Ulkus, LE, 2007)

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (50.00)29.6817
2010's1 (50.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
McDermott, U1
Sharma, SV1
Dowell, L1
Greninger, P1
Montagut, C1
Lamb, J1
Archibald, H1
Raudales, R1
Tam, A1
Lee, D1
Rothenberg, SM1
Supko, JG1
Sordella, R1
Ulkus, LE1
Iafrate, AJ1
Maheswaran, S1
Njauw, CN1
Tsao, H1
Drew, L1
Hanke, JH1
Ma, XJ1
Erlander, MG1
Gray, NS1
Haber, DA1
Settleman, J1
Yano, S1
Nakagawa, T1

Other Studies

2 other studies available for cl 387785 and Neoplasms

ArticleYear
Identification of genotype-correlated sensitivity to selective kinase inhibitors by using high-throughput tumor cell line profiling.
    Proceedings of the National Academy of Sciences of the United States of America, 2007, Dec-11, Volume: 104, Issue:50

    Topics: Antineoplastic Agents; Cell Line, Tumor; Drug Resistance, Neoplasm; Drug Screening Assays, Antitumor

2007
The current state of molecularly targeted drugs targeting HGF/Met.
    Japanese journal of clinical oncology, 2014, Volume: 44, Issue:1

    Topics: Acrylamides; Afatinib; Aminopyridines; Antibodies, Monoclonal; Antineoplastic Agents; Carcinoma, Non

2014