cl 387785 has been researched along with Neoplasms in 2 studies
CL 387785: structure in first source
N-{4-[(3-bromophenyl)amino]quinazolin-6-yl}but-2-ynamide : A member of the class of quinazolines that is 4,6-diaminoquinazoine in which the one of the hydrogens attached to the amino group at position 4 has been replaced by a m-bromophenyl group while one of the hydrogens attached to the amino group at position 6 has been replaced by a but-2-ynoyl group.
Neoplasms: New abnormal growth of tissue. Malignant neoplasms show a greater degree of anaplasia and have the properties of invasion and metastasis, compared to benign neoplasms.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Genetically defined cancer subsets, irrespective of tissue type, predict response to kinase inhibitors, and provide an important preclinical model to guide early clinical applications of novel targeted inhibitors." | 1.34 | Identification of genotype-correlated sensitivity to selective kinase inhibitors by using high-throughput tumor cell line profiling. ( Archibald, H; Dowell, L; Drew, L; Erlander, MG; Gray, NS; Greninger, P; Haber, DA; Hanke, JH; Iafrate, AJ; Lamb, J; Lee, D; Ma, XJ; Maheswaran, S; McDermott, U; Montagut, C; Njauw, CN; Raudales, R; Rothenberg, SM; Settleman, J; Sharma, SV; Sordella, R; Supko, JG; Tam, A; Tsao, H; Ulkus, LE, 2007) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (50.00) | 29.6817 |
| 2010's | 1 (50.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| McDermott, U | 1 |
| Sharma, SV | 1 |
| Dowell, L | 1 |
| Greninger, P | 1 |
| Montagut, C | 1 |
| Lamb, J | 1 |
| Archibald, H | 1 |
| Raudales, R | 1 |
| Tam, A | 1 |
| Lee, D | 1 |
| Rothenberg, SM | 1 |
| Supko, JG | 1 |
| Sordella, R | 1 |
| Ulkus, LE | 1 |
| Iafrate, AJ | 1 |
| Maheswaran, S | 1 |
| Njauw, CN | 1 |
| Tsao, H | 1 |
| Drew, L | 1 |
| Hanke, JH | 1 |
| Ma, XJ | 1 |
| Erlander, MG | 1 |
| Gray, NS | 1 |
| Haber, DA | 1 |
| Settleman, J | 1 |
| Yano, S | 1 |
| Nakagawa, T | 1 |
2 other studies available for cl 387785 and Neoplasms
| Article | Year |
|---|---|
Identification of genotype-correlated sensitivity to selective kinase inhibitors by using high-throughput tumor cell line profiling.
Topics: Antineoplastic Agents; Cell Line, Tumor; Drug Resistance, Neoplasm; Drug Screening Assays, Antitumor | 2007 |
The current state of molecularly targeted drugs targeting HGF/Met.
Topics: Acrylamides; Afatinib; Aminopyridines; Antibodies, Monoclonal; Antineoplastic Agents; Carcinoma, Non | 2014 |