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cl 387785 and Adenomatous Polyposis Coli

cl 387785 has been researched along with Adenomatous Polyposis Coli in 1 studies

CL 387785: structure in first source
N-{4-[(3-bromophenyl)amino]quinazolin-6-yl}but-2-ynamide : A member of the class of quinazolines that is 4,6-diaminoquinazoine in which the one of the hydrogens attached to the amino group at position 4 has been replaced by a m-bromophenyl group while one of the hydrogens attached to the amino group at position 6 has been replaced by a but-2-ynoyl group.

Adenomatous Polyposis Coli: A polyposis syndrome due to an autosomal dominant mutation of the APC genes (GENES, APC) on CHROMOSOME 5. The syndrome is characterized by the development of hundreds of ADENOMATOUS POLYPS in the COLON and RECTUM of affected individuals by early adulthood.

Research

Studies (1)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (100.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Torrance, CJ1
Jackson, PE1
Montgomery, E1
Kinzler, KW1
Vogelstein, B1
Wissner, A1
Nunes, M1
Frost, P1
Discafani, CM1

Other Studies

1 other study available for cl 387785 and Adenomatous Polyposis Coli

ArticleYear
Combinatorial chemoprevention of intestinal neoplasia.
    Nature medicine, 2000, Volume: 6, Issue:9

    Topics: Adenomatous Polyposis Coli; Aminoquinolines; Aniline Compounds; Animals; Anti-Inflammatory Agents, N

2000