cl-316243 has been researched along with Diabetes-Mellitus--Type-1* in 1 studies
1 other study(ies) available for cl-316243 and Diabetes-Mellitus--Type-1
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Evaluation of Glucose Uptake and Uncoupling Protein 1 Activity in Adipose Tissue of Diabetic Mice upon β-Adrenergic Stimulation.
Regulation of metabolic activity in adipose tissue is of great concern for treating obesity. This study aimed to evaluate the adrenergic regulation of glucose uptake and the thermogenic program in adipose tissues in mouse models of both type 1 and 2 diabetes mellitus (DM).. Male mice were treated with streptozotocin to induce type 1 (T1) DM, and obese ob/ob mice were used for the type 2 (T2) DM model. After selective β. In T1DM, [. The metabolic response against adrenergic stimulation varied depending on the type of adipose tissue and DM. This could be important for the therapeutic activation of adipose tissue metabolism in obese diabetic patients. Topics: Adipose Tissue; Adrenergic Agents; Animals; Blood Glucose; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Dioxoles; Disease Models, Animal; Glucose; Male; Mice, Inbred ICR; Uncoupling Protein 1 | 2019 |