citrulline and Pulmonary Hypertension

citrulline has been researched along with Pulmonary Hypertension in 23 studies

Research

Studies (23)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's9 (39.13)29.6817
2010's10 (43.48)24.3611
2020's4 (17.39)2.80

Authors

AuthorsStudies
Cunningham, G; Dikalova, A; Douglass, M; Fike, CD; Kaplowitz, MR; Summar, M; Zhang, Y1
Aschner, JL; Avachat, C; Birnbaum, AK; Fike, CD; Sherwin, CM1
Aschner, JL; Cunningham, G; Dikalova, A; Fike, CD; Kaplowitz, MR; Summar, M2
Cabrera, M; Dodelson de Kremer, R; Grosso, CL; Juaneda, E; Laróvere, LE; Silvera Ruiz, S; Tablada, M1
Aschner, JL; Aschner, M; Dikalova, A; Fagiana, A; Fike, CD; Summar, M1
Aschner, JL; Fike, CD; Summar, M1
Lin, HC; Ma, L; Neu, J; Zhou, P1
Beyer, J; Ewert, R; Halank, M; Hoeffken, G; Kolditz, M; Opitz, C; Rubens, C; Schellong, S1
Blackwelder, WC; Hazen, SL; Kato, GJ; Machado, RF; Taylor, JG; Wang, Z1
Ananthakrishnan, M; Barr, FE; Cunningham, G; Fike, CD; Kaplowitz, M; Magarik, J; Smith, HA; Summar, ML; Zhang, Y1
Barr, FE; Macrae, D1
Summar, M; Ware, LB1
Aschner, JL; Eaton, F; Magarik, J; Rey-Parra, GJ; Summar, M; Thébaud, B; Vadivel, A; Zeng, H1
Datar, SA; Fineman, JR; Oishi, P1
Aschner, JL; Aschner, M; Cunningham, G; Fike, CD; Kaplowitz, M; Prince, LS; Sidoryk-Wegrzynowicz, M; Summar, M; Zhang, Y1
Calvert, TJ; Chen, B; Chicoine, LG; Jin, Y; Liu, Y; Nelin, LD1
Waugh, WH1
Czp, A1
Barr, FE; Canter, JA; Christian, KG; Christman, BW; Drinkwater, DC; Rice, GD; Scholl, FG; Smith, HA; Summar, ML1
Aggoun, Y; Beghetti, M; Da Cruz, E1
Burmester, GR; Feist, E1
Arnold, J; Barr, FE; Campbell, A; Canter, JA; Christian, KG; Cunningham, G; Drinkwater, DC; Kavanaugh-McHugh, A; Rice, G; Scholl, F; Smith, HA; Summar, ML; Taylor, MB; Tirona, RG1

Reviews

5 review(s) available for citrulline and Pulmonary Hypertension

ArticleYear
L-citrulline provides a novel strategy for treating chronic pulmonary hypertension in newborn infants.
    Acta paediatrica (Oslo, Norway : 1992), 2014, Volume: 103, Issue:10

    Topics: Amino Acid Transport Systems, Neutral; Animals; Cardiovascular Diseases; Citrulline; Endothelial Cells; Humans; Hypertension, Pulmonary; Hypoxia; Infant, Newborn; Models, Animal; Nitric Oxide; Nitric Oxide Synthase Type III

2014
Potential Nutrients for Preventing or Treating Bronchopulmonary Dysplasia.
    Paediatric respiratory reviews, 2017, Volume: 22

    Topics: Acetylcysteine; Antioxidants; Arginine; Bronchopulmonary Dysplasia; Citrulline; Cysteine; Fatty Acids, Unsaturated; Glutamine; Humans; Hypertension, Pulmonary; Infant; Infant, Newborn; Infant, Premature; Inositol; Selenium; Vitamin A; Vitamin B Complex

2017
Inhaled nitric oxide and related therapies.
    Pediatric critical care medicine : a journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies, 2010, Volume: 11, Issue:2 Suppl

    Topics: Administration, Inhalation; Administration, Oral; Arginine; Cardiac Surgical Procedures; Child; Child, Preschool; Citrulline; Clinical Trials as Topic; Endothelium-Dependent Relaxing Factors; Humans; Hypertension, Pulmonary; Infant; Infant, Newborn; Injections, Intravenous; Nitric Oxide; Postoperative Complications

2010
Advances in the management of pediatric pulmonary hypertension.
    Respiratory care, 2011, Volume: 56, Issue:9

    Topics: Animals; Antihypertensive Agents; Bosentan; Child; Citrulline; Drug Therapy, Combination; Endothelium, Vascular; Hemodynamics; Humans; Hypertension, Pulmonary; Infant; Infant, Newborn; Muscle Contraction; Persistent Fetal Circulation Syndrome; Phosphodiesterase 5 Inhibitors; Piperazines; PPAR gamma; Prostaglandins; Purines; Sildenafil Citrate; Sulfonamides; Sulfones; Vascular Resistance; Vasoconstriction; Ventricular Function, Right

2011
[Rheumatology 2007].
    Deutsche medizinische Wochenschrift (1946), 2007, Jun-22, Volume: 132, Issue:25-26

    Topics: Antirheumatic Agents; Arthritis, Rheumatoid; Citrulline; Collagen Diseases; Drug Therapy, Combination; Humans; Hypertension, Pulmonary; Rare Diseases; Scleroderma, Systemic; Vasculitis

2007

Trials

2 trial(s) available for citrulline and Pulmonary Hypertension

ArticleYear
Efficacy of citrulline supplementation to decrease the risk of pulmonary hypertension after congenital heart disease surgery. A local experience.
    Revista de la Facultad de Ciencias Medicas (Cordoba, Argentina), 2020, 12-01, Volume: 77, Issue:4

    Topics: Cardiac Surgical Procedures; Child; Citrulline; Dietary Supplements; Heart Defects, Congenital; Humans; Hypertension, Pulmonary

2020
Nitric oxide precursors and congenital heart surgery: a randomized controlled trial of oral citrulline.
    The Journal of thoracic and cardiovascular surgery, 2006, Volume: 132, Issue:1

    Topics: Administration, Oral; Arginine; Blood Pressure; Cardiac Surgical Procedures; Child, Preschool; Citrulline; Double-Blind Method; Female; Fontan Procedure; Humans; Hypertension, Pulmonary; Infant; Male; Multivariate Analysis; Pilot Projects; Postoperative Complications

2006

Other Studies

16 other study(ies) available for citrulline and Pulmonary Hypertension

ArticleYear
Folic acid, either solely or combined with L-citrulline, improves NO signaling and ameliorates chronic hypoxia-induced pulmonary hypertension in newborn pigs.
    Physiological reports, 2021, Volume: 9, Issue:21

    Topics: Animals; Citrulline; Drug Combinations; Female; Folic Acid; Hypertension, Pulmonary; Hypoxia; Male; Nitric Oxide; Pulmonary Artery; Signal Transduction; Swine; Vascular Resistance

2021
Pharmacokinetics of L-Citrulline in Neonates at Risk of Developing Bronchopulmonary Dysplasia-Associated Pulmonary Hypertension.
    Paediatric drugs, 2023, Volume: 25, Issue:1

    Topics: Arginine; Bronchopulmonary Dysplasia; Child; Citrulline; Gestational Age; Humans; Hypertension, Pulmonary; Infant; Infant, Newborn

2023
Combined l-citrulline and tetrahydrobiopterin therapy improves NO signaling and ameliorates chronic hypoxia-induced pulmonary hypertension in newborn pigs.
    American journal of physiology. Lung cellular and molecular physiology, 2020, 04-01, Volume: 318, Issue:4

    Topics: Animals; Animals, Newborn; Arginine; Biopterins; Citrulline; Hypertension, Pulmonary; Hypoxia; Nitric Oxide; Nitric Oxide Synthase Type III; Pulmonary Artery; Signal Transduction; Swine; Vascular Resistance

2020
Sodium-coupled neutral amino acid transporter 1 (SNAT1) modulates L-citrulline transport and nitric oxide (NO) signaling in piglet pulmonary arterial endothelial cells.
    PloS one, 2014, Volume: 9, Issue:1

    Topics: Amino Acid Transport System A; Animals; Biological Transport; Cell Hypoxia; Cells, Cultured; Citrulline; Endothelial Cells; Endothelium, Vascular; Hypertension, Pulmonary; Nitric Oxide; Nitric Oxide Synthase Type III; Pulmonary Artery; Signal Transduction; Superoxides; Sus scrofa

2014
Rescue Treatment with L-Citrulline Inhibits Hypoxia-Induced Pulmonary Hypertension in Newborn Pigs.
    American journal of respiratory cell and molecular biology, 2015, Volume: 53, Issue:2

    Topics: Animals; Animals, Newborn; Arginine; Cell Hypoxia; Citrulline; Drug Evaluation, Preclinical; Hypertension, Pulmonary; Sus scrofa

2015
L-arginine plasma levels and severity of idiopathic pulmonary arterial hypertension.
    VASA. Zeitschrift fur Gefasskrankheiten, 2008, Volume: 37, Issue:1

    Topics: Adult; Aged; Arginine; Biomarkers; Blood Pressure; Cardiac Catheterization; Chromatography, High Pressure Liquid; Citrulline; Cohort Studies; Exercise Test; Female; Hemodynamics; Humans; Hypertension, Pulmonary; Male; Middle Aged; Pilot Projects; Pulmonary Artery; Severity of Illness Index

2008
Endogenous nitric oxide synthase inhibitors in sickle cell disease: abnormal levels and correlations with pulmonary hypertension, desaturation, haemolysis, organ dysfunction and death.
    British journal of haematology, 2009, Volume: 145, Issue:4

    Topics: Anemia, Sickle Cell; Arginine; Case-Control Studies; Citrulline; Follow-Up Studies; Hemolysis; Humans; Hypertension, Pulmonary; Kidney Diseases; Linear Models; Nitric Oxide Synthase; omega-N-Methylarginine; Oxygen; Proportional Hazards Models; Risk; Survival Rate

2009
L-Citrulline ameliorates chronic hypoxia-induced pulmonary hypertension in newborn piglets.
    American journal of physiology. Lung cellular and molecular physiology, 2009, Volume: 297, Issue:3

    Topics: Amino Acids; Animals; Animals, Newborn; Blotting, Western; Chronic Disease; Citrulline; Exhalation; Hemodynamics; Hypertension, Pulmonary; Hypoxia; In Vitro Techniques; Lung; Nitrates; Nitric Oxide; Nitric Oxide Synthase Type I; Nitric Oxide Synthase Type III; Perfusion; Pressure; Pulmonary Artery; Sus scrofa

2009
Understanding the role of NOS-3 in ventilator-induced lung injury: don't take NO for an answer.
    American journal of physiology. Lung cellular and molecular physiology, 2010, Volume: 299, Issue:2

    Topics: Animals; Citrulline; Humans; Hypertension, Pulmonary; Mice; Nitric Oxide Synthase Type III; Ventilator-Induced Lung Injury

2010
L-citrulline attenuates arrested alveolar growth and pulmonary hypertension in oxygen-induced lung injury in newborn rats.
    Pediatric research, 2010, Volume: 68, Issue:6

    Topics: Animals; Animals, Newborn; Arginine; Bronchopulmonary Dysplasia; Citrulline; Disease Models, Animal; Humans; Hypertension, Pulmonary; Infant, Newborn; Lung; Lung Injury; Nitric Oxide; Pulmonary Alveoli; Rats

2010
Prolonged hypoxia augments L-citrulline transport by system A in the newborn piglet pulmonary circulation.
    Cardiovascular research, 2012, Aug-01, Volume: 95, Issue:3

    Topics: Amino Acid Transport System A; Animals; Animals, Newborn; Biological Transport; Cells, Cultured; Chronic Disease; Citrulline; Disease Models, Animal; Endothelial Cells; Familial Primary Pulmonary Hypertension; Hypertension, Pulmonary; Hypoxia; Membrane Transport Modulators; Nitric Oxide; Pulmonary Artery; Pulmonary Circulation; Swine; Time Factors

2012
Chronic hypoxia decreases arterial and venous compliance in isolated perfused rat lungs: an effect that is reversed by exogenous L-arginine.
    American journal of physiology. Heart and circulatory physiology, 2013, Jan-15, Volume: 304, Issue:2

    Topics: Animals; Arginine; Blood Pressure; Chronic Disease; Citrulline; Compliance; Disease Models, Animal; Dose-Response Relationship, Drug; Enzyme Inhibitors; Hemodynamics; Hypertension, Pulmonary; Hypoxia; Lung; Nitric Oxide; Nitric Oxide Donors; Nitric Oxide Synthase; Perfusion; Pulmonary Artery; Pulmonary Veins; Rats; Rats, Sprague-Dawley; Time Factors; Vascular Resistance; Vasoconstriction; Ventricular Dysfunction, Right

2013
Arginine metabolism, pulmonary hypertension, and sickle cell disease.
    JAMA, 2005, Nov-16, Volume: 294, Issue:19

    Topics: Anemia, Sickle Cell; Arginase; Arginine; Citrulline; Dietary Supplements; Humans; Hypertension, Pulmonary

2005
Citrulline, Viagra and BiDil--bad medicine.
    Alternative medicine review : a journal of clinical therapeutic, 2005, Volume: 10, Issue:4

    Topics: Adult; Arginine; Chronic Disease; Citrulline; Cyclic GMP; Endothelium, Vascular; Erectile Dysfunction; Humans; Hypertension, Pulmonary; Infant; Male; Marketing; Nitric Oxide; Piperazines; Purines; Sildenafil Citrate; Sulfones; Vasodilator Agents

2005
Nitric oxide precursors and congenital cardiac surgery: a randomized controlled trial of oral citrulline. Definition of pulmonary hypertension in Fontan circulation?
    The Journal of thoracic and cardiovascular surgery, 2006, Volume: 132, Issue:6

    Topics: Administration, Oral; Citrulline; Fontan Procedure; Heart Defects, Congenital; Humans; Hypertension, Pulmonary; Nitric Oxide; Postoperative Complications; Randomized Controlled Trials as Topic

2006
Pharmacokinetics and safety of intravenously administered citrulline in children undergoing congenital heart surgery: potential therapy for postoperative pulmonary hypertension.
    The Journal of thoracic and cardiovascular surgery, 2007, Volume: 134, Issue:2

    Topics: Cardiac Surgical Procedures; Child; Child, Preschool; Citrulline; Dose-Response Relationship, Drug; Female; Heart Defects, Congenital; Humans; Hypertension, Pulmonary; Infant; Infusions, Intravenous; Injections, Intravenous; Male; Treatment Outcome

2007