citrulline and Multiple Sclerosis

citrulline has been researched along with Multiple Sclerosis in 33 studies

Research

Studies (33)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	6 (18.18)	18.2507
2000's	15 (45.45)	29.6817
2010's	12 (36.36)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Atzori, L; Cocco, E; Liggi, S; Lorefice, L; Marrosu, MG; Murgia, F; Poddighe, S	1
Beelen, R; D'haeseleer, M; De Keyser, J; Nagels, G; Van Binst, AM; Vande Vyver, M; Verborgh, C	1
Gudmann, NS; Hansen, NU; Jensen, AC; Karsdal, MA; Siebuhr, AS	1
Alpayci, M; Aydin, MN; Bayram, Y; Delen, V; Guducuoglu, H; Milanlioglu, A	1
Piao, H; Tan, D; Yang, L	1
'tHart, BA; Gran, B; Kap, YS; Laman, JD; Morandi, E	1
Apostolopoulos, V; Chatzantoni, K; Deraos, G; Deraos, S; Katsara, M; Matsoukas, J; Matsoukas, MT; Mouzaki, A; Papathanasopoulos, P; Tselios, T; Vynios, D	1
Anzilotti, C; Migliorini, P; Pratesi, F; Tommasi, C	1
Papini, AM	1
Bhattacharya, SK; Dave, KR; Ding, D; Enriquez-Algeciras, M; Perez-Pinzon, M	1
Baka, Z; Buzás, EI; Falus, A; Géher, P; György, B; Nagy, G	1
Azebi, S; Batsché, E; Christensen, T; England, P; Muchardt, C; Møller-Larsen, A; Petersen, T; Sharma, P	1
Ackerley, C; Lei, H; Li, Z; Mastronardi, FG; Moscarello, MA; Raijmakers, R; Tsui, H; Winer, S; Wood, DD; Zhang, L	1
Arandjelovic, S; Fernandez-Castaneda, A; Gaultier, A; Gonias, SL; Mowen, KA; Schlobach, RK; Stiles, TL	1
Armstrong, S; Bates, IR; Hallett, FR; Harauz, G; Hill, CM; Libich, DS; Siemiarczuk, A	1
Echols, JD; Nicholas, AP; Sambandam, T; Tourtellotte, WW	1
Robinson, WH; Vossenaar, ER	1
Caponi, L; Cornelis, F; Cournu-Rebeix, I; Fontaine, B; Migliorini, P; Petit-Teixeira, E; Pierlot, C; Tommasi, C	1
Harauz, G; Musse, AA	1
Mastronardi, FG; Moscarello, MA; Wood, DD	1
Casaccia-Bonnefil, P; Dosch, HM; Mastronardi, FG; Mei, J; Moscarello, MA; Probert, L; Raijmakers, R; Tseveleki, V; Wood, DD	1
Mastronardi, FG; Moscarello, MA; Noor, A; Paton, T; Wood, DD	1
Elkabes, S; Grant, JE; Hu, J; Jain, MR; Li, H; Liu, T	1
Bodil Roth, E; Larsson, A; Londos, E; Sandberg-Wollheim, M; Sjöberg, K; Stenberg, P; Theander, E	1
Goodin, RR; Martin, R; McFarland, HF; Rhame, L; Whitaker, JN	1
Ackerley, CA; Mak, B; Mastronardi, FG; Moscarello, MA; Roots, BI	1
Ackerley, CA; Groome, N; Mastronardi, FG; Moscarello, MA; Yon, M	1
Bilbao, JM; Moscarello, MA; O'Connors, P; Wood, DD	1
Beniac, DR; Harauz, G; Moscarello, MA; Ottensmeyer, FP; Palaniyar, N; Wood, DD	2
Ackerley, C; Boggs, JM; Koshy, KM; Moscarello, MA; Rangaraj, G; Wood, DD	1
Harauz, G; Joshi, S; Moscarello, MA; Pritzker, LB	1
de Seze, J; Dubucquoi, S; Dutoit, V; Lefranc, D; Nuez, I; Prin, L; Vermersch, P; Virecoulon, F	1

Reviews

8 review(s) available for citrulline and Multiple Sclerosis

Article	Year
Biological relevance of citrullinations: diagnostic, prognostic and therapeutic options. Autoimmunity, 2015, Volume: 48, Issue:2 Topics: Arginine; Arthritis, Rheumatoid; Autoantibodies; Benzamidines; Biomarkers; Citrulline; Enzyme Inhibitors; Fibrosis; Humans; Hydrolases; Isoenzymes; Multiple Sclerosis; Neoplasms; Protein Processing, Post-Translational; Protein-Arginine Deiminases; Spondylitis, Ankylosing	2015
Myelin Basic Protein Citrullination in Multiple Sclerosis: A Potential Therapeutic Target for the Pathology. Neurochemical research, 2016, Volume: 41, Issue:8 Topics: Animals; Citrulline; Drug Delivery Systems; Humans; Hydrolases; Immunologic Factors; Multiple Sclerosis; Myelin Basic Protein; Neuroprotective Agents; Protein-Arginine Deiminases	2016
EBV Infection and Multiple Sclerosis: Lessons from a Marmoset Model. Trends in molecular medicine, 2016, Volume: 22, Issue:12 Topics: Animals; Antigen Presentation; B-Lymphocytes; Citrulline; Disease Models, Animal; Encephalomyelitis, Autoimmune, Experimental; Epstein-Barr Virus Infections; Herpesvirus 4, Human; Humans; Immunity, Cellular; Major Histocompatibility Complex; Multiple Sclerosis; T-Lymphocytes	2016
Peptidylarginine deiminase 4 and citrullination in health and disease. Autoimmunity reviews, 2010, Volume: 9, Issue:3 Topics: Animals; Arthritis, Rheumatoid; Citrulline; Gene Expression Regulation; Genetic Predisposition to Disease; Humans; Hydrolases; Multiple Sclerosis; Protein-Arginine Deiminase Type 4; Protein-Arginine Deiminases	2010
The use of post-translationally modified peptides for detection of biomarkers of immune-mediated diseases. Journal of peptide science : an official publication of the European Peptide Society, 2009, Volume: 15, Issue:10 Topics: Arthritis, Rheumatoid; Autoantibodies; Autoimmune Diseases; Autoimmunity; Biomarkers; Citrulline; Filaggrin Proteins; Humans; Intermediate Filament Proteins; Lupus Erythematosus, Systemic; Multiple Sclerosis; Myelin Proteins; Myelin-Associated Glycoprotein; Myelin-Oligodendrocyte Glycoprotein; Peptide Library; Peptides; Protein Processing, Post-Translational	2009
Citrullination under physiological and pathological conditions. Joint bone spine, 2012, Volume: 79, Issue:5 Topics: Arthritis, Rheumatoid; Cell Transformation, Neoplastic; Central Nervous System; Citrulline; Gene Expression Regulation; Humans; Immune System; Multiple Sclerosis; Protein Processing, Post-Translational; Proteins; Psoriasis; Skin Physiological Phenomena	2012
A tale of two citrullines--structural and functional aspects of myelin basic protein deimination in health and disease. Neurochemical research, 2007, Volume: 32, Issue:2 Topics: Amino Acid Sequence; Animals; Arthritis, Rheumatoid; Citrulline; Humans; Hydrolases; Molecular Sequence Data; Multiple Sclerosis; Myelin Basic Protein; Myelin Sheath; Protein Conformation; Protein Processing, Post-Translational; Protein-Arginine Deiminases	2007
The role of citrullinated proteins suggests a novel mechanism in the pathogenesis of multiple sclerosis. Neurochemical research, 2007, Volume: 32, Issue:2 Topics: Apoptosis; Citrulline; Humans; Hydrolases; Methylation; Multiple Sclerosis; Myelin Basic Protein; Oligodendroglia; Protein Conformation; Protein Processing, Post-Translational; Protein-Arginine Deiminases	2007

Trials

1 trial(s) available for citrulline and Multiple Sclerosis

Article	Year
Metabolomic analysis identifies altered metabolic pathways in Multiple Sclerosis. The international journal of biochemistry & cell biology, 2017, Volume: 93 Topics: Adult; Aged; Asparagine; Citrulline; Female; Gas Chromatography-Mass Spectrometry; Humans; Male; Metabolome; Metabolomics; Middle Aged; Multiple Sclerosis	2017

Other Studies

24 other study(ies) available for citrulline and Multiple Sclerosis

Article	Year
Plasma citrulline levels are increased in patients with multiple sclerosis. Journal of the neurological sciences, 2018, 04-15, Volume: 387 Topics: Adult; Aged; Arginine; Citrulline; Disability Evaluation; Female; Glutamine; Humans; Immunologic Factors; Magnetic Resonance Imaging; Male; Middle Aged; Multiple Sclerosis; Myelin Basic Protein; Nitric Oxide; Statistics, Nonparametric	2018
Anti-CCP antibody levels are not associated with MS: results from a case-control study. BioMed research international, 2015, Volume: 2015 Topics: Adult; Antibodies, Anti-Idiotypic; Arthritis, Rheumatoid; Central Nervous System; Citrulline; Early Diagnosis; Female; Humans; Male; Middle Aged; Multiple Sclerosis; Myelin Basic Protein; Peptides	2015
Citrullination of linear and cyclic altered peptide ligands from myelin basic protein (MBP(87-99)) epitope elicits a Th1 polarized response by T cells isolated from multiple sclerosis patients: implications in triggering disease. Journal of medicinal chemistry, 2008, Dec-25, Volume: 51, Issue:24 Topics: Animals; Chemistry, Pharmaceutical; Citrulline; Drug Design; Epitopes; Humans; Leukocytes, Mononuclear; Ligands; Models, Chemical; Multiple Sclerosis; Myelin Basic Protein; Peptides; Peptides, Cyclic; Th1 Cells	2008
The role of deimination in ATP5b mRNA transport in a transgenic mouse model of multiple sclerosis. EMBO reports, 2012, Mar-01, Volume: 13, Issue:3 Topics: Adenosine Triphosphate; Animals; ATP Synthetase Complexes; Cell Line; Citrulline; Disease Models, Animal; Enzyme Activation; Gene Expression; Mice; Mice, Transgenic; Mitochondria; Mitochondrial Proton-Translocating ATPases; Multiple Sclerosis; Nuclear Proteins; Protein Binding; Protein Transport; Rats; RNA Transport; RNA-Binding Proteins; RNA, Messenger; Transcription Factors	2012
Citrullination of histone H3 interferes with HP1-mediated transcriptional repression. PLoS genetics, 2012, Volume: 8, Issue:9 Topics: Adult; Chromobox Protein Homolog 5; Chromosomal Proteins, Non-Histone; Citrulline; Endogenous Retroviruses; Female; Gene Expression Regulation; HEK293 Cells; Histones; Humans; Hydrolases; Immunity, Innate; Interleukin-8; Leukocytes, Mononuclear; Lymphocyte Activation; Male; MCF-7 Cells; Middle Aged; Multiple Sclerosis; Ornithine; Protein-Arginine Deiminase Type 4; Protein-Arginine Deiminases; T-Lymphocytes; Tumor Necrosis Factor-alpha	2012
Inhibition of peptidyl-arginine deiminases reverses protein-hypercitrullination and disease in mouse models of multiple sclerosis. Disease models & mechanisms, 2013, Volume: 6, Issue:2 Topics: Amidines; Animals; Brain; CD3 Complex; Citrulline; Demyelinating Diseases; Disease Models, Animal; Encephalomyelitis, Autoimmune, Experimental; Enzyme Inhibitors; Humans; Hydrolases; Lymphocytes; Mice; Mice, Inbred C57BL; Mice, Transgenic; Multiple Sclerosis; Optic Nerve; Protein-Arginine Deiminases; Spleen; Survival Analysis	2013
Identification of the low density lipoprotein (LDL) receptor-related protein-1 interactome in central nervous system myelin suggests a role in the clearance of necrotic cell debris. The Journal of biological chemistry, 2013, Feb-15, Volume: 288, Issue:7 Topics: Animals; Apoptosis; Central Nervous System; Citrulline; Cloning, Molecular; Endocytosis; Glutathione Transferase; Green Fluorescent Proteins; Homeostasis; Humans; Jurkat Cells; Ligands; Low Density Lipoprotein Receptor-Related Protein-1; Mass Spectrometry; Mice; Multiple Sclerosis; Myelin Sheath; Necrosis; Phagocytosis; Proteomics	2013
Interaction of the 18.5-kD isoform of myelin basic protein with Ca2+ -calmodulin: effects of deimination assessed by intrinsic Trp fluorescence spectroscopy, dynamic light scattering, and circular dichroism. Protein science : a publication of the Protein Society, 2003, Volume: 12, Issue:7 Topics: Acrylamides; Amino Acid Sequence; Animals; Calcium; Calmodulin; Cations, Divalent; Circular Dichroism; Citrulline; Humans; Molecular Sequence Data; Multiple Sclerosis; Myelin Basic Protein; Protein Isoforms; Scattering, Radiation; Spectrometry, Fluorescence	2003
Increased citrullinated glial fibrillary acidic protein in secondary progressive multiple sclerosis. The Journal of comparative neurology, 2004, May-17, Volume: 473, Issue:1 Topics: Adult; Aged; Aged, 80 and over; Astrocytes; Blotting, Western; Brain; Brain Chemistry; Citrulline; Female; Glial Fibrillary Acidic Protein; Humans; Immunohistochemistry; Male; Middle Aged; Multiple Sclerosis; Postmortem Changes; Protein Isoforms	2004
Citrullination and autoimmune disease: 8th Bertine Koperberg meeting. Annals of the rheumatic diseases, 2005, Volume: 64, Issue:10 Topics: Arthritis, Rheumatoid; Autoimmune Diseases; Citrulline; Humans; Multiple Sclerosis	2005
PADI4 gene in multiple sclerosis: a family-based association study. Journal of neuroimmunology, 2006, Volume: 177, Issue:1-2 Topics: Adult; Biomarkers; Central Nervous System; Chromosome Mapping; Citrulline; DNA Mutational Analysis; Female; France; Genetic Markers; Genetic Predisposition to Disease; Genetic Testing; Genotype; Haplotypes; Humans; Hydrolases; Male; Multiple Sclerosis; Myelin Basic Protein; Myelin Sheath; Polymorphism, Single Nucleotide; Protein Processing, Post-Translational; Protein-Arginine Deiminase Type 4; Protein-Arginine Deiminases; White People	2006
Increased citrullination of histone H3 in multiple sclerosis brain and animal models of demyelination: a role for tumor necrosis factor-induced peptidylarginine deiminase 4 translocation. The Journal of neuroscience : the official journal of the Society for Neuroscience, 2006, Nov-01, Volume: 26, Issue:44 Topics: Active Transport, Cell Nucleus; Animals; Brain; Citrulline; Demyelinating Diseases; Disease Models, Animal; Female; Histones; Humans; Hydrolases; Mice; Mice, Inbred C57BL; Mice, Transgenic; Multiple Sclerosis; Protein-Arginine Deiminase Type 4; Protein-Arginine Deiminases; Tumor Necrosis Factor-alpha	2006
Peptidyl argininedeiminase 2 CpG island in multiple sclerosis white matter is hypomethylated. Journal of neuroscience research, 2007, Volume: 85, Issue:9 Topics: 5-Methylcytosine; Blotting, Western; Brain; Citrulline; CpG Islands; DNA; DNA, Single-Stranded; Fluorescent Antibody Technique; Humans; Hydrolases; Methylation; Multiple Sclerosis; Myelin Basic Protein; Promoter Regions, Genetic; Protein-Arginine Deiminase Type 2; Protein-Arginine Deiminases; Reverse Transcriptase Polymerase Chain Reaction; Sulfites; Thymus Gland	2007
Post-translational modifications in the rat lumbar spinal cord in experimental autoimmune encephalomyelitis. Journal of proteome research, 2007, Volume: 6, Issue:7 Topics: Amino Acid Sequence; Animals; Arginine; Astrocytes; Citrulline; Encephalomyelitis, Autoimmune, Experimental; Glial Fibrillary Acidic Protein; Lumbar Vertebrae; Lysine; Methylation; Molecular Sequence Data; Multiple Sclerosis; Phosphorylation; Protein Processing, Post-Translational; Proteomics; Rats; Serine; Spinal Cord	2007
Pathogenesis of autoimmune diseases: antibodies against transglutaminase, peptidylarginine deiminase and protein-bound citrulline in primary Sjögren's syndrome, multiple sclerosis and Alzheimer's disease. Scandinavian journal of immunology, 2008, Volume: 67, Issue:6 Topics: Alzheimer Disease; Autoantibodies; Autoimmune Diseases; Citrulline; Enzyme-Linked Immunosorbent Assay; GTP-Binding Proteins; Humans; Hydrolases; Multiple Sclerosis; Protein Glutamine gamma Glutamyltransferase 2; Protein-Arginine Deiminases; Proteins; Sjogren's Syndrome; Transglutaminases	2008
Citrulline-containing myelin basic protein is recognized by T-cell lines derived from multiple sclerosis patients and healthy individuals. Neurology, 1994, Volume: 44, Issue:1 Topics: Adult; Amino Acid Sequence; Antigen-Presenting Cells; Cell Line; Citrulline; Female; Humans; Lymphocyte Activation; Male; Middle Aged; Molecular Sequence Data; Multiple Sclerosis; Myelin Basic Protein; Reference Values; Stereoisomerism; T-Lymphocytes	1994
Modifications of myelin basic protein in DM20 transgenic mice are similar to those in myelin basic protein from multiple sclerosis. The Journal of clinical investigation, 1996, Jan-15, Volume: 97, Issue:2 Topics: Animals; Citrulline; Demyelinating Diseases; Encephalomyelitis, Autoimmune, Experimental; Gene Dosage; Hydrolases; Isoelectric Point; Mice; Mice, Mutant Strains; Mice, Transgenic; Multiple Sclerosis; Myelin Basic Protein; Myelin Proteolipid Protein; Protein-Arginine Deiminase Type 4; Protein-Arginine Deiminases	1996
Identification of a mitogen-activated protein kinase site in human myelin basic protein in situ. Journal of neuroimmunology, 1996, Volume: 65, Issue:1 Topics: Amino Acid Sequence; Antibody Specificity; Binding Sites; Brain; Calcium-Calmodulin-Dependent Protein Kinases; Citrulline; Humans; Immunohistochemistry; Microscopy, Electron; Mitogens; Molecular Sequence Data; Multiple Sclerosis; Myelin Basic Protein; Myelin Sheath; Phosphorylation; Threonine	1996
Acute multiple sclerosis (Marburg type) is associated with developmentally immature myelin basic protein. Annals of neurology, 1996, Volume: 40, Issue:1 Topics: Adult; Antibodies, Monoclonal; Arginine; Blotting, Western; Brain; Brain Chemistry; Chronic Disease; Citrulline; Demyelinating Diseases; Fatal Outcome; Female; Humans; Lymphocytes; Macrophages; Magnetic Resonance Imaging; Multiple Sclerosis; Myelin Basic Protein	1996
Marburg's variant of multiple sclerosis correlates with a less compact structure of myelin basic protein. Molecular cell biology research communications : MCBRC, 1999, Volume: 1, Issue:1 Topics: Acute Disease; Autoantigens; Citrulline; Humans; Image Processing, Computer-Assisted; Microscopy, Electron; Microscopy, Electron, Scanning Transmission; Multiple Sclerosis; Myelin Basic Protein; Protein Conformation; Protein Isoforms	1999
Highly deiminated isoform of myelin basic protein from multiple sclerosis brain causes fragmentation of lipid vesicles. Journal of neuroscience research, 1999, Aug-15, Volume: 57, Issue:4 Topics: Animals; Arginine; Cattle; Citrulline; Electrochemistry; Humans; Imines; Light; Liposomes; Multiple Sclerosis; Myelin Basic Protein; Protein Isoforms; Scattering, Radiation	1999
Cryoelectron microscopy of protein-lipid complexes of human myelin basic protein charge isomers differing in degree of citrullination. Journal of structural biology, 2000, Volume: 129, Issue:1 Topics: Adult; Arginine; Autoimmune Diseases; Citrulline; Cryoelectron Microscopy; G(M1) Ganglioside; Humans; Image Processing, Computer-Assisted; Immunohistochemistry; Macromolecular Substances; Microscopy, Electron, Scanning; Multiple Sclerosis; Myelin Basic Protein; Phosphatidylserines; Protein Isoforms; Protein Processing, Post-Translational	2000
Deimination of myelin basic protein. 2. Effect of methylation of MBP on its deimination by peptidylarginine deiminase. Biochemistry, 2000, May-09, Volume: 39, Issue:18 Topics: Animals; Arginine; Brain; Cathepsin D; Cattle; Citrulline; Humans; Hydrolases; Kinetics; Mass Spectrometry; Methylation; Multiple Sclerosis; Myelin Basic Protein; Peptide Fragments; Protein Processing, Post-Translational; Protein Structure, Secondary; Protein Structure, Tertiary; Protein-Arginine Deiminase Type 4; Protein-Arginine Deiminases	2000
IgG reactivity against citrullinated myelin basic protein in multiple sclerosis. Journal of neuroimmunology, 2001, Jul-02, Volume: 117, Issue:1-2 Topics: Adolescent; Adult; Aged; Amino Acid Sequence; Citrulline; Enzyme-Linked Immunosorbent Assay; Female; Humans; Immunoglobulin G; Male; Middle Aged; Molecular Sequence Data; Multiple Sclerosis; Myelin Basic Protein; Protein Processing, Post-Translational	2001