citrulline has been researched along with Innate Inflammatory Response in 70 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (2.86) | 18.7374 |
| 1990's | 1 (1.43) | 18.2507 |
| 2000's | 16 (22.86) | 29.6817 |
| 2010's | 37 (52.86) | 24.3611 |
| 2020's | 14 (20.00) | 2.80 |
| Authors | Studies |
|---|---|
| Faßbender, J; Holthoff, HP; Li, Z; Reimann, A; Ungerer, M; Wenhart, C | 1 |
| Breuillard, C; Corne, C; Couchet, M; Fontaine, E; Moinard, C; Pestour, S; Rendu, J | 1 |
| Jiang, P; Li, G; Mao, Y; Shi, D | 1 |
| Balcerczyk, A; Biesiekierska, M; Ciesielski, O; Panthu, B; Pirola, L; Soszyński, M | 1 |
| Crawford, JM; Flavell, RA; Oh, J; Wei, Z | 1 |
| Deutz, NEP; Engelen, MPKJ; Ten Have, GAM; Thaden, JJ; Wierzchowska-McNew, RA | 1 |
| Huang, X; Jiang, G; Ming, S; Qu, S; Wei, J; Wu, Y; Zhang, G | 1 |
| Belik, J; Gauda, EB; Higazy, R; Ivanovska, J; Ivanovski, N; Kim, P; Leung, S; Li, D; Miraglia, E; Mohammadi, A; Nagy, A; Palaniyar, N; Pan, J; Posiewko, M; Santyr, G; Tran, H; Wang, H | 1 |
| De Pietri, S; Frandsen, TL; Hasle, H; Moser, C; Müller, K; Nersting, J; Nielsen, CH; Rathe, M; Weischendorff, S | 1 |
| Iannaccone, A; Radic, MZ | 1 |
| Brooks, SR; Buckner, JH; Carlucci, PM; Carmona-Rivera, C; Fox, DA; Goel, RR; Hoffmann, V; James, E; Kaplan, MJ; Rims, C | 1 |
| Corcos, O; Peoc'h, K; Soudan, D; Treton, X; Uzzan, M; Weiss, E | 1 |
| Azeredo, R; Conceição, LEC; Costas, B; Dias, J; Fernández-Boo, S; Fontinha, F; Machado, M | 1 |
| Kutty, SN; Li, Y; Liang, P; Lin, X; Qin, G; Rikard, H; Zhou, C | 1 |
| Choi, JY; Choi, M; Ivashkiv, LB; Kim, JS; Kim, JY; Lee, EY; Song, JS | 1 |
| De Bandt, JP; Jegatheesan, P; M'bouyou-Boungou, J; Nakib, S; Nubret, E; Ouelaa, W; Vicente, C | 1 |
| Bast, A; Decroix, L; Descat, A; Drittij-Reijnders, MJ; Heyman, E; Meeusen, R; Soares, DD; Stahl, W; Tonoli, C; Weseler, AR | 1 |
| Bonaventura, A; Camici, GG; Carbone, F; Dallegri, F; Diaz-Cañestro, C; Liberale, L; Montecucco, F; Vecchié, A | 1 |
| Cau, L; Méchin, MC; Simon, M | 1 |
| Authier, S; Brown, D; Donini, O; Measey, TJ; Pouliot, M; Swanson, C; Wierzbicki, W | 1 |
| Beidler, J; Figueroa, A; Hong, MY; Hooshmand, S; Kern, M | 1 |
| Agah, S; Darabi, Z; Darand, M; Faghihi, A; Hedayati, M; Hekmatdoost, A; Yari, Z | 1 |
| Bhardwaj, P; Dhatwalia, SK; Dhawan, DK; Kumar, M | 1 |
| Ballesteros-Pomar, MD; Calleja-Fernández, A; Cano-Rodríguez, I; Cordido, F; de Urbina-González, JJ; Vidal-Casariego, A | 1 |
| de Betue, CT; Deutz, NE | 1 |
| Dwivedi, N; Radic, M | 1 |
| Chowdhary, BP; Jackson, A; Johnson, P; Schulze, J; Steelman, SM | 1 |
| Boissinot, M; Burska, AN; Emery, P; Hunt, L; Nissim, A; Ponchel, F; Ryan, BJ; Strollo, R; Vital, E; Winyard, PG | 1 |
| Bastin, J; Cynober, L; De Bandt, JP; Durant, S; Forest, C; Jaubert, AM; Joffin, N; Moinard, C; Noirez, P | 1 |
| Nehru, B; Thakur, P | 1 |
| Catrina, AI; Klareskog, L; Malmström, V; Reynisdottir, G; Ytterberg, AJ | 1 |
| Bergum, B; Bielecka, E; Binder, V; Blom, AM; Brun, JG; Dahl-Knudsen, A; Enghild, JJ; Hellvard, A; Jonsson, R; Koro, C; Mydel, P; Potempa, J; Scavenius, C | 1 |
| Agostinis, P; Crèvecoeur, I; D'Hertog, W; Eizirik, DL; Ferreira, GB; Garg, AD; Gevaert, K; Mathieu, C; Overbergh, L; Rondas, D; Staes, A | 1 |
| Amital, H; Gertel, S | 1 |
| Åhlin, E; Elshafie, AI; Nur, MA; Rönnelid, J | 1 |
| Castermans, TM; Hommen, MP; Meesters, DM; Poeze, M; Wijnands, KA | 1 |
| Hung, CY; Lai, CH; Lee, CH; Lo, HC | 1 |
| Cheng, D; Fert-Bober, J; Gazitt, T; Lahey, LJ; Onuma, K; Rhodes, C; Robinson, WH; Sharpe, O; Shiao, R; Sohn, DH; Sokolove, J; Van Eyk, J; Wong, HH; Zhao, X | 1 |
| Berglin, E; Brouwer, E; Gregersen, PK; Huizinga, TW; Lindqvist, E; Mangnus, L; Rantapää-Dahlqvist, S; Reijnierse, M; van der Heijde, D; van der Helm-van Mil, AH; van Steenbergen, HW | 1 |
| Abu-Amara, D; Bersani, FS; Bierer, LM; Coy, M; Epel, ES; Flory, J; Lindqvist, D; Makotine, I; Marmar, C; Mellon, SH; Reus, VI; Wolkowitz, OM; Yehuda, R | 1 |
| Amara, K; Bas, DB; Bersellini Farinotti, A; Catrina, AI; Fernades-Cerqueira, C; Finn, A; Holmdahl, R; Jakobsson, PJ; Jimenez-Andrade, JM; Kato, J; Klareskog, L; Krishnamurthy, A; Lundberg, K; Malmström, V; Nandakumar, KS; Rogoz, K; Sandor, K; Su, J; Svensson, CI; Wigerblad, G | 1 |
| Fillipakopoulos, P; Ghari, F; Kawalkowska, J; Kessler, B; Knapp, S; La Thangue, NB; McGouran, J; Munro, S; Muth, A; Picaud, S; Quirke, AM; Subramanian, V; Thompson, PR; Venables, PJ; Williams, R | 1 |
| Bergheim, I; Beutheu, S; Butel, MJ; De Bandt, JP; Freese, K; Jegatheesan, P; Nubret, E; Waligora-Dupriet, AJ | 1 |
| Asayag, CR; Bream, JH; Caulfield, LE; Gratz, J; Kosek, MN; Kosek, PS; Lee, GO; Mduma, E; Olortegui, MP; Pan, WKY; Patil, C; Sanchez, GM; Svensen, E; Yori, PP | 1 |
| Breuillard, C; Curis, E; Cynober, L; Le Plénier, S; Moinard, C | 1 |
| Furukawa, H; Nakayama-Hamada, M; Suzuki, A; Yamada, R; Yamamoto, K | 1 |
| Beltrami, A; Fiorillo, MT; Kumar, P; Paladini, F; Rossmann, M; Saenger, W; Sorrentino, R; Uchanska-Ziegler, B; Ziegler, A | 1 |
| Conings, R; Dillen, C; Gouwy, M; Loos, T; Maudgal, PC; Mortier, A; Noppen, S; Opdenakker, G; Proost, P; Ronsse, I; Schutyser, E; Struyf, S; Van Damme, J | 1 |
| Campana, V; Moya, M; Palma, JA; Rubio, CR; Simes, JC; Soriano, F | 1 |
| Hsiao, CC; Lee, CH; Lo, HC; Tsao, LY | 1 |
| Bracci, F; Daniele, A; Diamanti, A; Gambarara, M; Goffredo, BM; Knafelz, D; Panetta, F; Papadatou, B; Pezzi, S; Torre, G | 1 |
| Andersson, P; Bylund, J; Egesten, A; Eliasson, M; Erjefält, JS; Kilsgård, O; Linge, HM; Malmsten, M; Nordin, SL; Olin, AI; Sörenson, E; Sørensen, OE | 1 |
| Kalandadze, IV; Mikeladze, DG; Ramsden, JJ; Shanshiashvili, LV | 1 |
| Cherrington, BD; Coonrod, SA; Horibata, S | 1 |
| Campana, VR; Cremonezzi, D; Dávila, S; Palma, JA; Simes, JC; Vignola, MB | 1 |
| Buia, R; Pârvu, AE; Pârvu, M; Pleşca-Manea, L; Puia, M; Taămaş, M | 1 |
| Cuzzocrea, S; Ischiropoulos, H; Salvemini, D | 1 |
| OPIE, EL | 1 |
| ALLISON, F; LANCASTER, MG | 1 |
| Abu-Soud, HM; Diamond, MP; Galijasevic, S; Saed, GM | 1 |
| Bajor, T; Farkas, A; Hrabák, A; Szabó, A; Vámos, R | 1 |
| Petzold, A; Plant, GT; Rejdak, K | 1 |
| Childress, B; Herrlinger-Garcia, KA; Hudgens, J; Langkamp-Henken, B; Percival, SS; Stechmiller, JK; Steele, R; Tian, L | 1 |
| Dirsch, VM; Erker, T; Handler, N; Heiss, EH; Schmitt, CA | 1 |
| Barnard, J; DiDonato, JA; Hazen, SL; Hörkkö, S; Kummu, O; Nicholls, SJ; Reynolds, WF; Rodriguez, ER; Topol, EJ; Wang, Z | 1 |
| Ischiropoulos, H; Rader, DJ | 1 |
| de Betue, CT; Deutz, NE; Engel, M; Luiking, YC; van Waardenburg, DA | 1 |
| Khan, SN; Neeli, I; Radic, M | 1 |
| Maarsingh, H; Meurs, H; Zaagsma, J | 1 |
| Bambery, P; Khullar, M; Sud, A; Wanchu, A | 1 |
11 review(s) available for citrulline and Innate Inflammatory Response
| Article | Year |
|---|---|
Citrullination in the pathology of inflammatory and autoimmune disorders: recent advances and future perspectives.
Topics: Autoimmune Diseases; Citrullination; Citrulline; COVID-19; Energy Metabolism; Extracellular Traps; Gene Expression Regulation; Humans; Inflammation; Neoplasms; Protein Processing, Post-Translational; Protein-Arginine Deiminases; SARS-CoV-2; Thromboembolism | 2022 |
The Pathophysiological Role of Neutrophil Extracellular Traps in Inflammatory Diseases.
Topics: Animals; Autoantigens; Autoimmunity; Biomarkers; Cardiovascular Diseases; Chromatin; Citrullination; Citrulline; Communicable Diseases; Disease Models, Animal; Extracellular Traps; Histones; Humans; Hydrolases; Inflammation; Metabolic Diseases; Neoplasms; Peroxidase; Protein-Arginine Deiminase Type 4; Protein-Arginine Deiminases; Risk Factors; Serine Proteases | 2018 |
Peptidylarginine deiminases and deiminated proteins at the epidermal barrier.
Topics: Animals; Arginine; Arthritis, Rheumatoid; Calcium; Citrulline; Epidermal Cells; Epidermis; Filaggrin Proteins; Gene Expression Profiling; Gene Expression Regulation; Humans; Hydrolases; Inflammation; Mice; Neoplasms; Neurodegenerative Diseases; Protein Processing, Post-Translational; Protein-Arginine Deiminases | 2018 |
Citrullination of autoantigens implicates NETosis in the induction of autoimmunity.
Topics: Autoantigens; Autoimmune Diseases; Autoimmunity; Bacterial Infections; Cell Death; Citrulline; Felty Syndrome; Histones; Humans; Hydrolases; Inflammation; Neutrophils; Protein Processing, Post-Translational; Protein-Arginine Deiminase Type 4; Protein-Arginine Deiminases | 2014 |
Autoantibodies to posttranslational modifications in rheumatoid arthritis.
Topics: Animals; Antigens; Antioxidants; Arthritis, Rheumatoid; Autoantibodies; B-Lymphocytes; Biomarkers; Citrulline; Humans; Inflammation; Oxygen; Protein Processing, Post-Translational; Reactive Oxygen Species | 2014 |
Lungs, joints and immunity against citrullinated proteins in rheumatoid arthritis.
Topics: Arthritis, Rheumatoid; Autoantibodies; Citrulline; Humans; Inflammation; Irritants; Joints; Lung; Peptides, Cyclic; Smoking | 2014 |
Putative approaches to bypass the citrulline-specific autoimmune response in rheumatoid arthritis.
Topics: Arthritis, Rheumatoid; Autoantibodies; Biomarkers; Citrulline; Humans; Inflammation; Molecular Targeted Therapy; Sensitivity and Specificity; Synovial Membrane | 2014 |
Arginine and citrulline and the immune response in sepsis.
Topics: Arginine; Citrulline; Endotoxemia; Humans; Immunity; Inflammation; Macrophages; Nitric Oxide; Sepsis; T-Lymphocytes | 2015 |
Role for peptidylarginine deiminase enzymes in disease and female reproduction.
Topics: Animals; Citrulline; Female; Gene Expression Regulation; HL-60 Cells; Humans; Hydrolases; Inflammation; Mice; Mice, Knockout; Models, Biological; Models, Chemical; Oocytes; Ovulation; Protein Processing, Post-Translational; Protein-Arginine Deiminases; Reproduction | 2012 |
Roles of nitric oxide and superoxide in inflammation.
Topics: 2-Naphthylamine; Animals; Arginine; Blotting, Western; Capillary Permeability; Chemotaxis, Leukocyte; Citrulline; Fluorescent Dyes; Fluorometry; Inflammation; Nitrates; Nitric Oxide; Nitrites; Oxidation-Reduction; Oxidative Stress; Peroxynitrous Acid; Rats; Superoxides; Tyrosine | 2003 |
Arginine homeostasis in allergic asthma.
Topics: Animals; Arginine; Asthma; Bronchial Hyperreactivity; Citrulline; Homeostasis; Humans; Hypersensitivity; Inflammation | 2008 |
5 trial(s) available for citrulline and Innate Inflammatory Response
| Article | Year |
|---|---|
Obesity- and sex-related metabolism of arginine and nitric oxide in adults.
Topics: Arginine; Chromatography, Liquid; Citrulline; Cross-Sectional Studies; Female; Humans; Inflammation; Male; Middle Aged; Nitric Oxide; Obesity, Morbid; Tandem Mass Spectrometry | 2022 |
Acute cocoa Flavanols intake has minimal effects on exercise-induced oxidative stress and nitric oxide production in healthy cyclists: a randomized controlled trial.
Topics: Adult; Antioxidants; Athletic Performance; Bicycling; Biomarkers; Cacao; Catechin; Citrulline; Cross-Over Studies; Cytokines; Double-Blind Method; Humans; Inflammation; Male; Malondialdehyde; Nitric Oxide; Oxidative Stress; Polyphenols; Uric Acid | 2017 |
Inflammatory markers response to citrulline supplementation in patients with non-alcoholic fatty liver disease: a randomized, double blind, placebo-controlled, clinical trial.
Topics: Alanine Transaminase; C-Reactive Protein; Citrulline; Dietary Supplements; Double-Blind Method; Humans; Inflammation; NF-kappa B; Non-alcoholic Fatty Liver Disease; Outcome Assessment, Health Care; Tumor Necrosis Factor-alpha | 2019 |
Efficacy of glutamine in the prevention of acute radiation enteritis: a randomized controlled trial.
Topics: Acute Disease; Aged; Citrulline; Double-Blind Method; Enteritis; Female; Glutamine; Humans; Inflammation; Intestinal Mucosa; Intestines; Leukocyte L1 Antigen Complex; Male; Middle Aged; Nutrition Assessment; Nutritional Status; Proportional Hazards Models; Radiotherapy | 2014 |
Arginine supplementation does not enhance serum nitric oxide levels in elderly nursing home residents with pressure ulcers.
Topics: Administration, Oral; Aged; Arginine; Citrulline; Dietary Supplements; Drug Monitoring; Female; Florida; Geriatric Assessment; Humans; Inflammation; Lymphocyte Activation; Male; Mitogens; Neutrophil Activation; Nitric Oxide; Nursing Homes; Nutrition Assessment; Nutritional Status; Ornithine; Pressure Ulcer; Respiratory Burst; Time Factors | 2005 |
54 other study(ies) available for citrulline and Innate Inflammatory Response
| Article | Year |
|---|---|
A fructosylated peptide derived from a collagen II T cell epitope for long-term treatment of arthritis (FIA-CIA) in mice.
Topics: Animals; Antigens, Differentiation, B-Lymphocyte; Arthritis; Arthritis, Rheumatoid; Autoimmunity; Cattle; Citrulline; Collagen Type II; Epitopes, T-Lymphocyte; Fructose; Histocompatibility Antigens Class II; Inflammation; Male; Mice; Mice, Inbred DBA; Peptides; Peptides, Cyclic | 2021 |
Regulation of citrulline synthesis in human enterocytes: Role of hypoxia and inflammation.
Topics: Arginine; Citrulline; Enterocytes; Humans; Hypoxia; Inflammation | 2022 |
Citrulline depletion by ASS1 is required for proinflammatory macrophage activation and immune responses.
Topics: Animals; Argininosuccinate Synthase; Citrulline; Disease Models, Animal; HEK293 Cells; Humans; Immunity, Innate; Inflammation; Inflammation Mediators; Janus Kinase 2; Listeria monocytogenes; Listeriosis; Macrophage Activation; Macrophages; Mice; Mice, Inbred C57BL; Mice, Knockout; Phosphorylation; RAW 264.7 Cells; Signal Transduction; STAT1 Transcription Factor | 2022 |
LACC1 bridges NOS2 and polyamine metabolism in inflammatory macrophages.
Topics: Animals; Arthritis; Citrulline; Cyanates; Humans; Inflammation; Inflammatory Bowel Diseases; Intracellular Signaling Peptides and Proteins; Macrophages; Mice; Nitric Oxide Synthase Type II; Ornithine; Ornithine Decarboxylase; Polyamines; Salmonella typhimurium | 2022 |
COVID-19 Metabolomic-Guided Amino Acid Therapy Protects from Inflammation and Disease Sequelae.
Topics: Animals; Citrulline; COVID-19; COVID-19 Drug Treatment; Glutamine; Humans; Inflammation; Mice | 2023 |
L-citrulline attenuates lipopolysaccharide-induced inflammatory lung injury in neonatal rats.
Topics: Animals; Animals, Newborn; Bronchopulmonary Dysplasia; Citrulline; Disease Models, Animal; Female; Humans; Hyperoxia; Infant, Newborn; Inflammation; Lipopolysaccharides; Lung; Lung Injury; Pneumonia; Pregnancy; Rats | 2023 |
Gastrointestinal barrier integrity and mucosal inflammation as risk factors of blood stream infections in children treated for acute lymphoblastic leukaemia.
Topics: Child; Citrulline; Humans; Inflammation; Mucositis; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Risk Factors | 2023 |
Increased Protein Citrullination as a Trigger for Resident Immune System Activation, Intraretinal Inflammation, and Promotion of Anti-retinal Autoimmunity: Intersecting Paths in Retinal Degenerations of Potential Therapeutic Relevance.
Topics: Animals; Autoimmunity; Citrullination; Citrulline; Humans; Immune System; Inflammation; Mice; Protein-Arginine Deiminases; Retinal Degeneration | 2019 |
Neutrophil extracellular traps mediate articular cartilage damage and enhance cartilage component immunogenicity in rheumatoid arthritis.
Topics: Animals; Arthritis, Rheumatoid; Autoantibodies; Autoantigens; Cartilage, Articular; Citrulline; Extracellular Traps; Humans; Inflammation; Mice; Neutrophils | 2020 |
Patients with COVID-19 present with low plasma citrulline concentrations that associate with systemic inflammation and gastrointestinal symptoms.
Topics: Abdominal Pain; Aged; Ageusia; Anorexia; Betacoronavirus; C-Reactive Protein; Citrulline; Coronavirus Infections; COVID-19; Diarrhea; Female; Ferritins; Humans; Inflammation; Male; Middle Aged; Nausea; Olfaction Disorders; Pandemics; Pneumonia, Viral; Prospective Studies; SARS-CoV-2; Serum Albumin; Severity of Illness Index; Vomiting | 2020 |
Dietary arginine and citrulline supplementation modulates the immune condition and inflammatory response of European seabass.
Topics: Animal Feed; Animals; Arginine; Bass; Citrulline; Diet; Dietary Supplements; Dose-Response Relationship, Drug; Fish Diseases; Gram-Negative Bacterial Infections; Immunity, Innate; Inflammation; Photobacterium; Random Allocation | 2020 |
[Strong inflammation is essential for expression of articular cartilage-specific citrullinated antigens].
Topics: Animals; Arthritis, Experimental; Autoantibodies; Cartilage, Articular; Citrulline; Humans; Inflammation; Mice; Rats; Rats, Sprague-Dawley | 2020 |
Implication of the Association of Fibrinogen Citrullination and Osteoclastogenesis in Bone Destruction in Rheumatoid Arthritis.
Topics: Animals; Arthritis, Rheumatoid; Bone and Bones; Bone Resorption; Cattle; Cell Differentiation; Citrullination; Citrulline; Fibrinogen; Humans; Inflammation; Integrin beta3; Leukocytes, Mononuclear; Lipopolysaccharide Receptors; NFATC Transcription Factors; Oligonucleotide Array Sequence Analysis; Osteoclasts; Osteogenesis; Synovial Fluid | 2020 |
Citrulline decreases hepatic endotoxin-induced injury in fructose-induced non-alcoholic liver disease: an ex vivo study in the isolated perfused rat liver.
Topics: Alanine Transaminase; Animals; Anti-Inflammatory Agents; Antioxidants; Citrulline; Dietary Supplements; Dyslipidemias; Fructose; Inflammation; Insulin Resistance; Lipopolysaccharides; Liver; Male; Non-alcoholic Fatty Liver Disease; Oxidative Stress; Rats, Sprague-Dawley; Toll-Like Receptor 4 | 2017 |
Pilot Study of Radiation-induced Gastrointestinal Injury in a Hemi-body Shielded Göttingen Minipig Model.
Topics: Acute Radiation Syndrome; Animals; Apoptosis; Blood Platelets; Citrulline; Collagen; Disease Models, Animal; Female; Fibrosis; Gastrointestinal Tract; Inflammation; Male; Pilot Projects; Radiation Dosage; Radiation Injuries, Experimental; Radiation Protection; Swine; Swine, Miniature; Whole-Body Irradiation | 2018 |
Watermelon and l-arginine consumption improve serum lipid profile and reduce inflammation and oxidative stress by altering gene expression in rats fed an atherogenic diet.
Topics: Animals; Anti-Inflammatory Agents; Antioxidants; Arginine; Atherosclerosis; C-Reactive Protein; Cardiovascular Diseases; Citrulline; Citrullus; Diet, Atherogenic; Dietary Supplements; Gene Expression; Gene Expression Regulation; Hydroxymethylglutaryl CoA Reductases; Inflammation; Lipid Metabolism; Lipids; Liver; Male; NF-kappa B; Oxidative Stress; Plant Preparations; Rats, Sprague-Dawley; Sterol Regulatory Element Binding Protein 2 | 2018 |
White tea - A cost effective alternative to EGCG in fight against benzo(a)pyrene (BaP) induced lung toxicity in SD rats.
Topics: Animals; Benzo(a)pyrene; Biomarkers; Camellia sinensis; Catechin; Citrulline; Female; Free Radical Scavengers; Inflammation; Lipid Peroxidation; Lung; Lung Injury; Nitric Oxide; Oxidative Stress; Plant Extracts; Protein Carbonylation; Rats, Sprague-Dawley; Reactive Oxygen Species; Tea | 2019 |
Changes in arginine metabolism during sepsis and critical illness in children.
Topics: Adult; Arginine; Child; Citrulline; Critical Illness; Dietary Supplements; Humans; Inflammation; Nitric Oxide; Sepsis | 2013 |
Serum metabolomics identifies citrulline as a predictor of adverse outcomes in an equine model of gut-derived sepsis.
Topics: Amino Acids; Analysis of Variance; Animals; Biomarkers; Citrulline; Disease Models, Animal; Enzyme-Linked Immunosorbent Assay; Fatty Acids; Hoof and Claw; Horses; Immunoglobulin A; Inflammation; Metabolomics; Polymerase Chain Reaction; Predictive Value of Tests; Principal Component Analysis; Reference Values; ROC Curve; Systemic Inflammatory Response Syndrome | 2014 |
Citrulline induces fatty acid release selectively in visceral adipose tissue from old rats.
Topics: Adipocytes; Age Factors; Animals; Carnitine O-Palmitoyltransferase; Cells, Cultured; Citrulline; Fatty Acids; Gene Expression Regulation; Inflammation; Intra-Abdominal Fat; Male; Organ Culture Techniques; Oxidation-Reduction; PPAR gamma; Rats, Sprague-Dawley | 2014 |
Inhibition of neuroinflammation and mitochondrial dysfunctions by carbenoxolone in the rotenone model of Parkinson's disease.
Topics: Animals; Antioxidants; Astrocytes; Carbenoxolone; Citrulline; Cytokines; Disease Models, Animal; Electron Transport; Enzyme Activation; Glial Fibrillary Acidic Protein; Glutathione; Inflammation; Inflammation Mediators; Male; Mesencephalon; Mitochondria; Nervous System; Nitric Oxide; Nitric Oxide Synthase Type II; Parkinson Disease; Rats, Sprague-Dawley; Rotenone | 2015 |
Carbamylation of immunoglobulin abrogates activation of the classical complement pathway.
Topics: Adhesins, Bacterial; Antibodies, Monoclonal, Murine-Derived; Antibody-Dependent Cell Cytotoxicity; Arthritis, Rheumatoid; Citrulline; Complement Activation; Complement C1q; Complement Pathway, Classical; Cyanates; Cysteine Endopeptidases; Gingipain Cysteine Endopeptidases; Humans; Immunoglobulin G; Immunologic Factors; Inflammation; Lysine; Mass Spectrometry; Protein Binding; Protein Processing, Post-Translational; Rituximab | 2014 |
Citrullinated glucose-regulated protein 78 is an autoantigen in type 1 diabetes.
Topics: Animals; Autoantigens; Biomarkers; Citrulline; Diabetes Mellitus, Type 1; Endoplasmic Reticulum Chaperone BiP; Gene Expression Regulation; Heat-Shock Proteins; Humans; Inflammation; Interferon-gamma; Interleukin-1beta; Mice; Mice, Inbred NOD | 2015 |
Anti-citrullinated peptide antibodies in Sudanese patients with Leishmania donovani infection exhibit reactivity not dependent on citrullination.
Topics: Adolescent; Adult; Aged; Antibodies, Protozoan; Antigen-Antibody Complex; Arthritis, Rheumatoid; Child; Child, Preschool; Citrulline; Complement C1q; Female; Humans; Inflammation; Leishmania donovani; Leishmaniasis, Visceral; Male; Middle Aged; Peptides; Peptides, Cyclic; Rheumatoid Factor; Sudan; Young Adult | 2015 |
Oral Citrulline Mitigates Inflammation and Jejunal Damage via the Inactivation of Neuronal Nitric Oxide Synthase and Nuclear Factor-κB in Intestinal Ischemia and Reperfusion.
Topics: Animals; Apoptosis; Arginine; Cell Proliferation; Citrulline; Cytokines; Glutamine; Inflammation; Interferon-gamma; Jejunum; Male; NF-kappa B; Nitric Oxide Synthase Type I; Ornithine; Rats; Rats, Wistar; Reperfusion Injury | 2017 |
Local Joint inflammation and histone citrullination in a murine model of the transition from preclinical autoimmunity to inflammatory arthritis.
Topics: Animals; Antigen-Antibody Complex; Arthritis, Rheumatoid; Autoantibodies; Autoimmunity; Citrulline; Disease Models, Animal; Disease Progression; Histones; Humans; Inflammation; Joints; Proteomics | 2015 |
Studies on ageing and the severity of radiographic joint damage in rheumatoid arthritis.
Topics: Adolescent; Adult; Age Factors; Aged; Aged, 80 and over; Aging; Arthritis, Rheumatoid; Autoantibodies; C-Reactive Protein; Citrulline; Cohort Studies; Europe; Female; Humans; Inflammation; Joints; Magnetic Resonance Imaging; Male; Middle Aged; North America; Peptides, Cyclic; Radiography; Severity of Illness Index | 2015 |
Global arginine bioavailability, a marker of nitric oxide synthetic capacity, is decreased in PTSD and correlated with symptom severity and markers of inflammation.
Topics: Adult; Arginine; Biological Availability; Biomarkers; C-Reactive Protein; Case-Control Studies; Citrulline; Depressive Disorder; Humans; Inflammation; Interleukin-1beta; Interleukin-6; Male; Nitric Oxide; Ornithine; Psychiatric Status Rating Scales; Stress Disorders, Post-Traumatic; Veterans | 2016 |
Autoantibodies to citrullinated proteins induce joint pain independent of inflammation via a chemokine-dependent mechanism.
Topics: Animals; Arthralgia; Autoantibodies; Behavior, Animal; Case-Control Studies; Chemokine CXCL1; Chemokines; Citrulline; Inflammation; Interleukin-8; Male; Mice; Mice, Inbred BALB C; Nociception; Osteoclasts; Receptors, Interleukin-8; Sulfonamides | 2016 |
Citrullination-acetylation interplay guides E2F-1 activity during the inflammatory response.
Topics: Acetylation; Animals; Arthritis, Experimental; Cell Cycle Proteins; Cell Line; Citrulline; Cytokines; E2F1 Transcription Factor; Gene Expression Regulation; HL-60 Cells; Humans; Hydrolases; Inflammation; Male; Mice; Mice, Inbred DBA; Nuclear Proteins; Promoter Regions, Genetic; Protein-Arginine Deiminase Type 4; Protein-Arginine Deiminases; Recombinant Proteins; RNA, Small Interfering; Transcription Factors | 2016 |
Preventive effects of citrulline on Western diet-induced non-alcoholic fatty liver disease in rats.
Topics: Animals; Anti-Inflammatory Agents; Antioxidants; Bacteroides; Citrulline; Claudin-1; Colon; Diet, Western; Endoplasmic Reticulum Stress; Inflammation; Insulin; Insulin Resistance; Interleukin-6; Lipid Droplets; Liver; Male; Non-alcoholic Fatty Liver Disease; Prevotella; Rats, Sprague-Dawley; RNA, Messenger; Toll-Like Receptor 4; Triglycerides; Tumor Necrosis Factor-alpha | 2016 |
Plasma Tryptophan and the Kynurenine-Tryptophan Ratio are Associated with the Acquisition of Statural Growth Deficits and Oral Vaccine Underperformance in Populations with Environmental Enteropathy.
Topics: Anthropometry; Antibodies; Antibodies, Viral; Child Development; Child, Preschool; Citrulline; Cohort Studies; Cytokines; Enteritis; Female; Growth Disorders; Humans; Infant; Inflammation; Kynurenine; Linear Models; Male; Peru; Poliovirus Vaccine, Oral; Tanzania; Tetanus Toxoid; Tryptophan | 2016 |
Nitric oxide production by peritoneal macrophages from aged rats: A short term and direct modulation by citrulline.
Topics: Aging; Animals; Anti-Inflammatory Agents; Citrulline; Dietary Supplements; Humans; Inflammation; Lipopolysaccharides; Macrophages, Peritoneal; Nitric Oxide; Rats; Signal Transduction; Tumor Necrosis Factor-alpha | 2017 |
Citrullinated fibrinogen inhibits thrombin-catalysed fibrin polymerization.
Topics: Arginine; Blood Coagulation; Catalysis; Citrulline; Edetic Acid; Fibrin; Fibrinogen; Humans; Inflammation; Kinetics; Peptides; Substrate Specificity; Thrombin; Time Factors | 2008 |
Citrullination-dependent differential presentation of a self-peptide by HLA-B27 subtypes.
Topics: Antigen Presentation; Autoantigens; Citrulline; Crystallography, X-Ray; HLA-B Antigens; HLA-B27 Antigen; Humans; Inflammation; Peptides; Protein Processing, Post-Translational; Protein Structure, Quaternary; Spondylitis, Ankylosing; T-Lymphocytes, Cytotoxic | 2008 |
Citrullination of CXCL8 by peptidylarginine deiminase alters receptor usage, prevents proteolysis, and dampens tissue inflammation.
Topics: Animals; Arginine; Autoimmune Diseases; Citrulline; Cornea; Glycosylation; Humans; Hydrolases; Inflammation; Interleukin-8; Neovascularization, Physiologic; Phosphorylation; Protein Processing, Post-Translational; Protein-Arginine Deiminases; Rabbits | 2008 |
Inflammatory and oxidative stress markers in experimental crystalopathy: their modification by photostimulation.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Arthritis; Biomarkers; Calcium Pyrophosphate; Citrulline; Crystallization; Durapatite; Female; Fibrinogen; Hindlimb; Inflammation; Injections, Intra-Articular; Lasers, Gas; Low-Level Light Therapy; Nitric Oxide; Oxidative Stress; Rats | 2009 |
Dose effects of chronically infused nitric oxide synthase inhibitor N(G)-nitro-L-arginine methyl ester on anabolic response and arginine metabolism in rats with subacute peritonitis.
Topics: Acute Disease; Amino Acids; Animals; Arginine; Citrulline; Deficiency Diseases; Enzyme Inhibitors; Inflammation; Leukocytes; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Nitrogen; Parenteral Nutrition Solutions; Parenteral Nutrition, Total; Peritonitis; Rats; Rats, Wistar; Serum Albumin; Weight Gain | 2011 |
Plasma citrulline as surrogate marker of intestinal inflammation in pediatric and adolescent with Crohn's disease: preliminary report.
Topics: Adolescent; Biomarkers; C-Reactive Protein; Child; Citrulline; Crohn Disease; Feces; Glutamine; Humans; Inflammation; Intestines; Leukocyte L1 Antigen Complex; Research Report; ROC Curve | 2011 |
Peptidylarginine deiminases present in the airways during tobacco smoking and inflammation can citrullinate the host defense peptide LL-37, resulting in altered activities.
Topics: Antimicrobial Cationic Peptides; Bronchi; Cathelicidins; Circular Dichroism; Citrulline; Electrophoresis, Polyacrylamide Gel; Haemophilus influenzae; Hydrolases; Immunohistochemistry; Inflammation; Mass Spectrometry; Protein-Arginine Deiminase Type 2; Protein-Arginine Deiminases; Proteolysis; Pseudomonas aeruginosa; Smoking; Staphylococcus aureus; Streptococcus pneumoniae; Trachea | 2012 |
Adhesive properties and inflammatory potential of citrullinated myelin basic protein peptide 45-89.
Topics: Animals; Biotransformation; Blotting, Western; Cell Adhesion; Cell Death; Cell Survival; Cells, Cultured; Chromatography, High Pressure Liquid; Citrulline; Inflammation; Lipids; Microglia; Myelin Basic Protein; NF-kappa B; Nitric Oxide; Oligodendroglia; Peptide Fragments; Rats; Rats, Wistar; Spectrum Analysis | 2012 |
Evaluation of inflammatory biomarkers associated with oxidative stress and histological assessment of magnetic therapy on experimental myopathy in rats.
Topics: Animals; Biomarkers; Citrulline; Female; Fibrinogen; Inflammation; Magnetic Field Therapy; Muscular Diseases; Nitric Oxide; Oxidative Stress; Rats; Rats, Wistar; Superoxide Dismutase | 2012 |
Effects of Melilotus officinalis on acute inflammation.
Topics: Acute-Phase Reaction; Animals; Anti-Inflammatory Agents; Citrulline; Coumarins; Hydrocortisone; Inflammation; Leukocyte Count; Male; Melilotus; Nitric Oxide; Phagocytosis; Phytotherapy; Plant Extracts; Plant Structures; Rabbits; Turpentine | 2002 |
On the relation of inflammation to the chemical constitution of injurious agents. On the pharmacology of inflammation.
Topics: Acids; Alkalies; Arginine; Citrulline; Electrolytes; Histamine; Inflammation; Proteins | 1963 |
PATHOGENESIS OF ACUTE INFLAMMATION. VI. INFLUENCE OF OSMOLARITY AND CERTAIN METABOLIC ANTAGONISTS UPON PHAGOCYTOSIS AND ADHESIVENESS BY LEUCOCYTES RECOVERED FROM MAN.
Topics: Adhesiveness; Aminocaproates; Aminocaproic Acid; Citrulline; Dinitrophenols; Edetic Acid; Glycine; Hypertonic Solutions; Inflammation; Isoflurophate; Leukocytes; Lysine; Neutrophils; Ornithine; Osmolar Concentration; Pathology; Phagocytosis; Pharmacology; Pralidoxime Compounds; Quinidine; Research | 1965 |
Myeloperoxidase up-regulates the catalytic activity of inducible nitric oxide synthase by preventing nitric oxide feedback inhibition.
Topics: Animals; Arginine; Catalysis; Chromatography, High Pressure Liquid; Citrulline; Electrochemistry; Escherichia coli; Feedback, Physiological; Hydrogen Peroxide; Inflammation; Kinetics; Mice; Milk; Models, Biological; Models, Chemical; Nitrates; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Nitrites; Oxygen; Peroxidase; Protein Binding; RNA, Messenger; Spectrophotometry; Time Factors; Ultraviolet Rays; Up-Regulation | 2003 |
The inhibition of retinal inducible nitric oxide synthase overexpression and the attenuation of experimental uveitis by anti-inflammatory drugs in rats.
Topics: Animals; Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal; Blotting, Western; Citrulline; Dexamethasone; Disease Models, Animal; Enzyme Inhibitors; Female; Indomethacin; Inflammation; Leukocytes; Lipopolysaccharides; Macrophages; Male; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Phagocytosis; Rats; Rats, Wistar; Retina; Time Factors; Uveitis | 2004 |
Axonal degeneration and inflammation in acute optic neuritis.
Topics: Acute Disease; Adult; Biomarkers; Case-Control Studies; Citrulline; Female; Humans; Inflammation; Male; Neurofilament Proteins; Nitrogen Oxides; Optic Neuritis; Prognosis; Prospective Studies; Visual Acuity | 2004 |
No evidence for modulation of endothelial nitric oxide synthase by the olive oil polyphenol hydroxytyrosol in human endothelial cells.
Topics: Cardiovascular Diseases; Cell Line; Citrulline; Endothelial Cells; Flavonoids; Genes, Reporter; Humans; Inflammation; Luciferases; Nitric Oxide; Nitric Oxide Synthase Type III; Olive Oil; Phenols; Phenylethyl Alcohol; Plant Oils; Polyphenols; Transcriptional Activation; Wine | 2007 |
Protein carbamylation links inflammation, smoking, uremia and atherogenesis.
Topics: Animals; Atherosclerosis; Blood Proteins; Carbamates; Cholesterol; Citrulline; Clinical Trials as Topic; Coronary Artery Disease; Cyanates; Dose-Response Relationship, Drug; Female; Foam Cells; Humans; Inflammation; Jurkat Cells; Lipoproteins, LDL; Macrophages; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Mice, Transgenic; Models, Biological; Oxidation-Reduction; Peroxidase; Predictive Value of Tests; Protein Processing, Post-Translational; Receptors, LDL; Scavenger Receptors, Class A; Smoking; Uremia | 2007 |
'Multipurpose oxidase' in atherogenesis.
Topics: Animals; Apoptosis; Atherosclerosis; Carbamates; Cardiovascular Diseases; Cell Proliferation; Citrulline; Endothelial Cells; Humans; Inflammation; Lipoproteins, HDL; Lipoproteins, LDL; Lysine; Macrophages; Mice; Models, Biological; Muscle, Smooth; Oxidation-Reduction; Peroxidase; Scavenger Receptors, Class A; Smoking; Substrate Specificity; Thiocyanates | 2007 |
Plasma arginine and citrulline concentrations in critically ill children: strong relation with inflammation.
Topics: Amino Acids; Arginine; C-Reactive Protein; Child; Child, Preschool; Citrulline; Critical Illness; Female; Humans; Infant; Inflammation; Male | 2007 |
Histone deimination as a response to inflammatory stimuli in neutrophils.
Topics: Apoptosis; Calcium; Cell Degranulation; Chromatin; Citrulline; Histones; HL-60 Cells; Humans; Imines; Inflammation; Ionophores; Neutrophils; Tretinoin | 2008 |
Nitric oxide production is increased in patients with inflammatory myositis.
Topics: Adolescent; Adult; Biomarkers; Citrulline; Dermatomyositis; Female; Humans; Inflammation; Male; Methotrexate; Middle Aged; Nitric Oxide; Nitrites; Polymyositis; Prednisolone; Reference Values | 1999 |