citrulline and Hypertension

citrulline has been researched along with Hypertension in 54 studies

Research

Studies (54)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's6 (11.11)18.2507
2000's12 (22.22)29.6817
2010's29 (53.70)24.3611
2020's7 (12.96)2.80

Authors

AuthorsStudies
Figueroa, A; Flores-Ramírez, AG; Garay-Sevilla, ME; Maharaj, A; Tovar-Villegas, VI1
Dillon, KN; Figueroa, A; Fischer, SM; Kang, Y; Maharaj, A; Martinez, MA3
Adachi, T; Hitomi, Y; Ido, Y; Ikegami, Y; Ishinoda, Y; Iwashita, M; Kagami, K; Kawai, A; Masaki, N; Miyazaki, K; Nagatomo, Y; Namba, T; Takase, B; Taruoka, A; Toya, T; Yasuda, R; Yumita, Y1
Drapała, A; Samborowska, E; Szlęzak, D; Ufnal, M; Wróbel, M1
Kim, SJ; Shao, YF; Sudarshan, VK; Wu, YN; Zhang, YH; Zhu, SC1
Allerton, TD; Dugas, TR; Irving, BA; Proctor, DN; Spielmann, G; Stephens, JM1
Casonatto, J; Enokida, DM; Grandolfi, K1
Grimm, D; Infanger, M; Khalaf, D; Krüger, M; Wehland, M1
El-Bassossy, HM; El-Fawal, R; Fahmy, A; Watson, ML1
Figueroa, A; Hooshmand, S; Sanchez-Gonzalez, MA; Wong, A1
Boehm, M; Cortese-Krott, MM; Gladwin, MT; Kato, GJ; Kelm, M; Kovacic, JC; Liu, VB; Noguchi, A; Raghavachari, N; Wang, X; Wood, KC1
Chien, SJ; Huang, CF; Huang, LT; Kuo, HC; Lin, KM; Lin, YJ; Tain, YL1
Chen, CC; Huang, LT; Kuo, HC; Sheen, JM; Tain, YL; Tiao, MM; Yu, HR1
Figueroa, A; Kalfon, R; Wong, A1
Chan, JY; Hsu, CN; Huang, LT; Lee, CT; Tain, YL1
Huang, LT; Lee, CT; Tain, YL1
Alvarez-Alvarado, S; Campbell, JC; Figueroa, A; Madzima, TA; Ormsbee, MJ; Wong, A1
Atzler, D; Böger, RH; Loots, I; Mels, CMC; Schutte, AE; Schwedhelm, E1
Chan, J; Lee, WC; Leu, S; Tain, YL; Wu, K1
Chien, SJ; Hsu, CN; Lin, IC; Lo, MH; Tain, YL1
Gonçalves, Mda C; Massa, NM; Persuhn, DC; Silva, AS; Silva, JD; Toscano, LT1
Alvarez-Alvarado, S; Figueroa, A; Jaime, SJ; Kalfon, R1
Aliani, M; Hanson, M; Taylor, CG; Zahradka, P1
Boldogh, I; Calderón-Cortés, E; Clemente-Guerrero, M; Cortés-Rojo, C; Manzo-Avalos, S; Saavedra-Molina, A; Villalobos-Molina, R1
Kato, K; Kemuriyama, T; Maruyama, S; Nishida, Y; Ohta, H; Sato, Y; Tandai-Hiruma, M1
Deutz, NE; Engelen, MP; Luiking, YC1
Lentz, SR; Murry, DJ; Rodionov, RN; Stevens, JW; Vaulman, SF1
Mayumi, M; Nagasaka, H; Tokuriki, S; Tsukahara, H1
Baylis, C; Chen, GF; Moningka, NC; Sasser, JM; Wagner, L; Zharikov, S1
Huang, LT; Lau, YT; Lin, CY; Lin, IC; Tain, YL1
Erez, A; Lee, B; Nagamani, SC1
Arjmandi, BH; Figueroa, A; Sanchez-Gonzalez, MA; Wong, A1
Chien, SJ; Hsu, CN; Huang, CF; Lin, YJ; Lo, MH; Tain, YL1
Ast, J; Bogdaski, P; Cielewicz, AR; Drozdowski, M; Jabecka, A; Pawlak-Lemaska, K; Pupek-Musialik, D1
Chien, SJ; Hsu, CN; Huang, CF; Huang, LT; Lin, YJ; Tain, YL1
Hagisawa, K; Kato, K; Kemuriyama, T; Nishida, Y; Ohta, H; Tandai-Hiruma, M; Tashiro, A1
Huynh, NT; Tayek, JA1
Bäcker, A; Bader, M; Bokemeyer, D; Cervenka, L; Ganten, D; Kramer, HJ; Malý, J; Mitchell, KD; Vanecková, I1
Hirakawa, H; Horiuchi, J; Kemuriyama, T; Nishida, Y; Sakamoto, H; Tandai-Hiruma, M1
Calderón-Cortés, E; Clemente-Guerrero, M; Cortés-Rojo, C; Gaona-Zamudio, FJ; Saavedra-Molina, A; Sierra-Campos, E; Villalobos-Molina, R1
Bellinghieri, G; De Luca, G; Di Giorgio, RM; Mallamace, A; Santoro, D; Savica, V1
Chen, PY; Sanders, PW2
Demontis, MP; Emanueli, C; Madeddu, P; Varoni, MV; Volpe, AR1
Chen, PY; Hamm, DA; Sanders, PW; Wood, PA1
Ichihara, A; Imig, JD; Navar, LG1
Cowley, AW; Maeda, CY; Mattson, DL; Szentiványi, M; Zou, AP1
Beyer, J; Daniel, WG; Garlichs, CD; Mügge, A; Plötze, K; Schellong, S; Schmeisser, A; Zhang, H1
Kashyap, M; Kh, R; Khullar, M; Pandhi, P; Uppal, R1
Fraser, T; Li, M; Turner, SW; Wang, J; Wen, C; Whitworth, JA1
Charpie, JR; Crowley, DC; D'Alecy, L; Goldberg, CS; Gomez, CA1
Hishikawa, K; Kato, R; Nakaki, T; Saruta, T; Suzuki, H1

Reviews

6 review(s) available for citrulline and Hypertension

ArticleYear
Effects of L-Citrulline Supplementation and Aerobic Training on Vascular Function in Individuals with Obesity across the Lifespan.
    Nutrients, 2021, Aug-27, Volume: 13, Issue:9

    Topics: Adolescent; Adult; Aged; Arginine; Atherosclerosis; Blood Pressure; Cardiometabolic Risk Factors; Cardiovascular Diseases; Child; Citrulline; Dietary Supplements; Endothelium, Vascular; Exercise; Female; Humans; Hypertension; Longevity; Male; Metabolic Diseases; Middle Aged; Nitric Oxide; Obesity; Vascular Stiffness; Vasodilation; Young Adult

2021
l-Citrulline Supplementation: Impact on Cardiometabolic Health.
    Nutrients, 2018, Jul-19, Volume: 10, Issue:7

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Antihypertensive Agents; Antioxidants; Citrulline; Diabetic Angiopathies; Dietary Supplements; Endothelium, Vascular; Evidence-Based Medicine; Humans; Hypertension; Hypoglycemic Agents; Insulin Resistance; Metabolic Syndrome; Models, Biological; Sarcopenia; Vascular Stiffness; Vasodilator Agents

2018
The Effects of Oral l-Arginine and l-Citrulline Supplementation on Blood Pressure.
    Nutrients, 2019, Jul-22, Volume: 11, Issue:7

    Topics: Administration, Oral; Antihypertensive Agents; Arginine; Blood Pressure; Citrulline; Humans; Hypertension

2019
Regulation of nitric oxide production in health and disease.
    Current opinion in clinical nutrition and metabolic care, 2010, Volume: 13, Issue:1

    Topics: Animals; Arginase; Arginine; Ascorbic Acid; Biopterins; Citrulline; Diet; Dietary Fats; Endothelium; Humans; Hypertension; Mice; Nitric Oxide; Nitric Oxide Synthase Type III; Sepsis

2010
Argininosuccinate lyase deficiency.
    Genetics in medicine : official journal of the American College of Medical Genetics, 2012, Volume: 14, Issue:5

    Topics: Arginine; Argininosuccinate Lyase; Argininosuccinic Acid; Argininosuccinic Aciduria; Child, Preschool; Citrulline; Cognition Disorders; Diet, Protein-Restricted; Fumarates; Genetic Testing; Glucose; Humans; Hyperammonemia; Hypertension; Infant; Infant, Newborn; Lipids; Liver Diseases; Liver Transplantation; Neonatal Screening; Phenylbutyrates; Sodium Benzoate

2012
L-arginine: a new opportunity in the management of clinical derangements in dialysis patients.
    Journal of renal nutrition : the official journal of the Council on Renal Nutrition of the National Kidney Foundation, 2006, Volume: 16, Issue:3

    Topics: Adult; Aged; Animals; Arginine; Citrulline; Diabetic Nephropathies; Endothelium, Vascular; Female; Humans; Hypertension; Kidney Failure, Chronic; Male; Middle Aged; Nitric Oxide; Renal Dialysis

2006

Trials

13 trial(s) available for citrulline and Hypertension

ArticleYear
Acute Citrulline Blunts Aortic Systolic Pressure during Exercise and Sympathoactivation in Hypertensive Postmenopausal Women.
    Medicine and science in sports and exercise, 2022, 05-01, Volume: 54, Issue:5

    Topics: Aged; Arterial Pressure; Blood Pressure; Citrulline; Dietary Supplements; Female; Humans; Hypertension; Male; Middle Aged; Postmenopause

2022
Effects of L-Citrulline Supplementation on Endothelial Function and Blood Pressure in Hypertensive Postmenopausal Women.
    Nutrients, 2022, Oct-20, Volume: 14, Issue:20

    Topics: Arginine; Blood Pressure; Citrulline; Dietary Supplements; Female; Humans; Hypertension; Nitric Oxide; Postmenopause; Pulse Wave Analysis; Vascular Stiffness

2022
Combined L-Citrulline Supplementation and Slow Velocity Low-Intensity Resistance Training Improves Leg Endothelial Function, Lean Mass, and Strength in Hypertensive Postmenopausal Women.
    Nutrients, 2022, Dec-23, Volume: 15, Issue:1

    Topics: Citrulline; Dietary Supplements; Female; Humans; Hypertension; Leg; Muscle Strength; Muscle, Skeletal; Postmenopause; Resistance Training

2022
Inter-Individual Responses to Citrulline Malate Oral Supplementation on Post-Exercise Hypotension in Hypertensives: A 24-Hour Analysis.
    Arquivos brasileiros de cardiologia, 2019, 07-10, Volume: 113, Issue:2

    Topics: Adult; Aged; Aged, 80 and over; Analysis of Variance; Anthropometry; Arginine; Blood Pressure; Citrulline; Double-Blind Method; Exercise; Exercise Test; Female; Humans; Hypertension; Malates; Male; Middle Aged; Nitric Oxide; Placebo Effect; Post-Exercise Hypotension; Reference Values; Statistics, Nonparametric; Time Factors; Treatment Outcome; Vasodilator Agents

2019
Effects of watermelon supplementation on arterial stiffness and wave reflection amplitude in postmenopausal women.
    Menopause (New York, N.Y.), 2013, Volume: 20, Issue:5

    Topics: Ankle Brachial Index; Aorta; Arginine; Blood Pressure; Citrulline; Citrullus; Cross-Over Studies; Dietary Supplements; Female; Fruit; Humans; Hypertension; Middle Aged; Obesity; Plant Extracts; Postmenopause; Pulse Wave Analysis; Vascular Stiffness

2013
Effects of watermelon supplementation on aortic hemodynamic responses to the cold pressor test in obese hypertensive adults.
    American journal of hypertension, 2014, Volume: 27, Issue:7

    Topics: Blood Pressure; Brachial Artery; Citrulline; Citrullus; Cold Temperature; Dietary Supplements; Double-Blind Method; Female; Hemodynamics; Humans; Hypertension; Male; Middle Aged; Obesity; Phytotherapy; Vascular Stiffness

2014
Impact of L-citrulline supplementation and whole-body vibration training on arterial stiffness and leg muscle function in obese postmenopausal women with high blood pressure.
    Experimental gerontology, 2015, Volume: 63

    Topics: Aging; Body Mass Index; Citrulline; Dietary Supplements; Exercise Therapy; Female; Humans; Hypertension; Leg; Middle Aged; Muscle Strength; Obesity; Postmenopause; Pulse Wave Analysis; Vascular Stiffness; Vibration

2015
Watermelon extract reduces blood pressure but does not change sympathovagal balance in prehypertensive and hypertensive subjects.
    Blood pressure, 2016, Volume: 25, Issue:4

    Topics: Arginine; Blood Pressure; Blood Pressure Determination; Citrulline; Citrullus; Dietary Supplements; Double-Blind Method; Female; Heart; Heart Rate; Humans; Hypertension; Male; Middle Aged; Sympathetic Nervous System

2016
l-Citrulline supplementation attenuates blood pressure, wave reflection and arterial stiffness responses to metaboreflex and cold stress in overweight men.
    The British journal of nutrition, 2016, Volume: 116, Issue:2

    Topics: Adaptation, Physiological; Adult; Aorta; Arterial Pressure; Citrulline; Cold Temperature; Dietary Supplements; Exercise; Humans; Hypertension; Ischemia; Male; Muscle, Skeletal; Obesity; Overweight; Pulse Wave Analysis; Stress, Physiological; Vascular Stiffness; Young Adult

2016
Watermelon extract supplementation reduces ankle blood pressure and carotid augmentation index in obese adults with prehypertension or hypertension.
    American journal of hypertension, 2012, Volume: 25, Issue:6

    Topics: Administration, Oral; Arginine; Blood Pressure; Brachial Artery; Carotid Arteries; Citrulline; Citrullus; Comorbidity; Female; Heart Rate; Humans; Hypertension; Male; Middle Aged; Obesity; Plant Extracts

2012
High citrulline-to-arginine ratio associated with blood pressure abnormalities in children with early chronic kidney disease.
    Circulation journal : official journal of the Japanese Circulation Society, 2013, Volume: 77, Issue:1

    Topics: Adolescent; Arginine; Biomarkers; Blood Pressure; Child; Child, Preschool; Citrulline; Female; Humans; Hypertension; Male; Renal Insufficiency, Chronic

2013
Oral L-arginine supplementation in patients with mild arterial hypertension and its effect on plasma level of asymmetric dimethylarginine, L-citruline, L-arginine and antioxidant status.
    European review for medical and pharmacological sciences, 2012, Volume: 16, Issue:12

    Topics: Administration, Oral; Adult; Antioxidants; Arginine; Blood Pressure Monitoring, Ambulatory; Citrulline; Dietary Supplements; Dose-Response Relationship, Drug; Double-Blind Method; Female; Humans; Hypertension; Male

2012
Oral arginine reduces systemic blood pressure in type 2 diabetes: its potential role in nitric oxide generation.
    Journal of the American College of Nutrition, 2002, Volume: 21, Issue:5

    Topics: Adult; Arginine; Blood Pressure; C-Peptide; Citrulline; Cross-Over Studies; Diabetes Mellitus, Type 2; Humans; Hypertension; Insulin; Kinetics; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type III; Prospective Studies

2002

Other Studies

35 other study(ies) available for citrulline and Hypertension

ArticleYear
A Low Arginine/Ornithine Ratio is Associated with Long-Term Cardiovascular Mortality.
    Journal of atherosclerosis and thrombosis, 2023, Oct-01, Volume: 30, Issue:10

    Topics: Aged; Arginine; Citrulline; Female; Humans; Hypertension; Male; Middle Aged; Ornithine; Prognosis

2023
Urinary excretion of asymmetric (ADMA) and symmetric (SDMA) dimethylarginine is positively related to nitric oxide level in tissues of normotensive and hypertensive rats.
    Amino acids, 2023, Volume: 55, Issue:4

    Topics: Animals; Arginine; Chromatography, Liquid; Citrulline; Hypertension; Male; Nitric Oxide; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Tandem Mass Spectrometry

2023
Functional interactions between complex I and complex II with nNOS in regulating cardiac mitochondrial activity in sham and hypertensive rat hearts.
    Pflugers Archiv : European journal of physiology, 2020, Volume: 472, Issue:12

    Topics: Angiotensin II; Animals; Cells, Cultured; Citrulline; Electron Transport Complex I; Electron Transport Complex II; Enzyme Inhibitors; Hypertension; Male; Malonates; Mitochondria, Heart; Myocytes, Cardiac; Nitric Oxide Synthase Type I; Oxygen Consumption; Rats; Rats, Sprague-Dawley; Rotenone; Thiourea

2020
Arginase inhibition alleviates hypertension in the metabolic syndrome.
    British journal of pharmacology, 2013, Volume: 169, Issue:3

    Topics: Animals; Antihypertensive Agents; Aorta, Thoracic; Arginase; Blood Pressure; Citrulline; Endothelium, Vascular; Enzyme Inhibitors; Hyperinsulinism; Hypertension; Hypertriglyceridemia; Hypolipidemic Agents; Insulin Resistance; Male; Metabolic Syndrome; Nitric Oxide; Ornithine; Random Allocation; Rats; Rats, Wistar; Reactive Oxygen Species; Valine

2013
Circulating blood endothelial nitric oxide synthase contributes to the regulation of systemic blood pressure and nitrite homeostasis.
    Arteriosclerosis, thrombosis, and vascular biology, 2013, Volume: 33, Issue:8

    Topics: Animals; Arginine; Blood Pressure; Carbon Radioisotopes; Citrulline; Endothelium, Vascular; Enzyme Inhibitors; Erythrocytes; Homeostasis; Hypertension; Mice; Mice, Knockout; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase Type III; Nitrites; Signal Transduction

2013
Two different approaches to restore renal nitric oxide and prevent hypertension in young spontaneously hypertensive rats: l-citrulline and nitrate.
    Translational research : the journal of laboratory and clinical medicine, 2014, Volume: 163, Issue:1

    Topics: Animals; Arginine; Citrulline; Dietary Supplements; Hypertension; Male; Nitrates; Nitric Oxide; Rats; Rats, Inbred SHR; Rats, Inbred WKY

2014
Maternal citrulline supplementation prevents prenatal dexamethasone-induced programmed hypertension.
    Free radical research, 2014, Volume: 48, Issue:5

    Topics: Animals; Blood Pressure; Citrulline; Dexamethasone; Dietary Supplements; Female; Humans; Hypertension; Nitric Oxide; Pregnancy; Rats; Rats, Sprague-Dawley

2014
Maternal citrulline supplementation prevents prenatal N(G)-nitro-L-arginine-methyl ester (L-NAME)-induced programmed hypertension in rats.
    Biology of reproduction, 2015, Volume: 92, Issue:1

    Topics: Animals; Blood Pressure; Citrulline; Dietary Supplements; Female; Hypertension; Male; Maternal Nutritional Physiological Phenomena; NG-Nitroarginine Methyl Ester; Pregnancy; Prenatal Exposure Delayed Effects; Rats; Rats, Sprague-Dawley; Renin-Angiotensin System

2015
Long-term effects of maternal citrulline supplementation on renal transcriptome prevention of nitric oxide depletion-related programmed hypertension: the impact of gene-nutrient interactions.
    International journal of molecular sciences, 2014, Dec-15, Volume: 15, Issue:12

    Topics: Animals; Blood Pressure; Citrulline; Dietary Supplements; Epigenesis, Genetic; Female; Food; Gene Expression Regulation, Developmental; Gene-Environment Interaction; Hypertension; Kidney; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Oxidative Stress; Pregnancy; Prenatal Exposure Delayed Effects; Rats; Rats, Sprague-Dawley; Transcriptome

2014
Nitric oxide synthesis capacity, ambulatory blood pressure and end organ damage in a black and white population: the SABPA study.
    Amino acids, 2016, Volume: 48, Issue:3

    Topics: Adult; Aged; Arginine; Biomarkers; Black People; Blood Pressure; Carotid Intima-Media Thickness; Citrulline; Cross-Sectional Studies; Female; Homoarginine; Humans; Hypertension; Male; Middle Aged; Nitric Oxide; South America; White People

2016
High salt exacerbates programmed hypertension in maternal fructose-fed male offspring.
    Nutrition, metabolism, and cardiovascular diseases : NMCD, 2015, Volume: 25, Issue:12

    Topics: Analysis of Variance; Animals; Animals, Newborn; Arginine; Blotting, Western; Chromatography, High Pressure Liquid; Citrulline; Female; Fructose; Hypertension; Male; Nitric Oxide; Pregnancy; Pregnancy, Animal; Proto-Oncogene Mas; Rats; Rats, Sprague-Dawley; Real-Time Polymerase Chain Reaction; Reference Values; Renin-Angiotensin System; Sodium Chloride, Dietary; Survival Rate

2015
Low urinary citrulline/arginine ratio associated with blood pressure abnormalities and arterial stiffness in childhood chronic kidney disease.
    Journal of the American Society of Hypertension : JASH, 2016, Volume: 10, Issue:2

    Topics: Adolescent; Arginine; Biomarkers; Blood Pressure; Blood Pressure Monitoring, Ambulatory; Child; Citrulline; Female; Humans; Hypertension; Male; Nitric Oxide; Nitric Oxide Synthase; Pulse Wave Analysis; Renal Insufficiency, Chronic; Taiwan; Vascular Remodeling; Vascular Stiffness

2016
Identification of urinary metabolites with potential blood pressure-lowering effects in lentil-fed spontaneously hypertensive rats.
    European journal of nutrition, 2018, Volume: 57, Issue:1

    Topics: Animals; Antihypertensive Agents; Blood Pressure; Citrulline; Diet; Hypertension; Lens Plant; Lysine; Male; Metabolomics; Pyridoxamine; Rats; Rats, Inbred SHR; Seeds

2018
Changes in mitochondrial functionality and calcium uptake in hypertensive rats as a function of age.
    Mitochondrion, 2008, Volume: 8, Issue:3

    Topics: Aging; Animals; Brain; Calcium; Citrulline; Egtazic Acid; Electron Transport Complex IV; Hypertension; Membrane Potential, Mitochondrial; Mitochondria; Nitric Oxide Synthase; Oxygen Consumption; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Species Specificity; Spectrometry, Fluorescence; Time Factors

2008
Endogenous angiotensin II has fewer effects but neuronal nitric oxide synthase has excitatory effects on renal sympathetic nerve activity in salt-sensitive hypertension-induced heart failure.
    The journal of physiological sciences : JPS, 2009, Volume: 59, Issue:4

    Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Brain; Citrulline; Enzyme Inhibitors; Heart Failure; Hypertension; Kidney; Losartan; Male; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type I; Pressoreceptors; Rats; Rats, Inbred Dahl; Renin-Angiotensin System; Sodium Chloride, Dietary; Sympathetic Nervous System; Thiourea

2009
Human alanine-glyoxylate aminotransferase 2 lowers asymmetric dimethylarginine and protects from inhibition of nitric oxide production.
    The Journal of biological chemistry, 2010, Feb-19, Volume: 285, Issue:8

    Topics: Adenoviridae; Animals; Arginine; Atherosclerosis; Chlorocebus aethiops; Citrulline; COS Cells; Diabetes Mellitus; Endothelial Cells; Gene Expression; Heart Failure; Humans; Hydrolysis; Hypertension; Kidney; Liver; Mice; Mitochondria; Nitric Oxide; Nitric Oxide Synthase; Transaminases; Transduction, Genetic

2010
Coupling of the citrulline recycling to endothelial NO production.
    Molecular genetics and metabolism, 2010, Volume: 99, Issue:4

    Topics: Citrulline; Endothelium; Humans; Hypertension; Nitric Oxide; Oxidative Stress; Urea Cycle Disorders, Inborn

2010
Effects of angiotensin type 1 receptor blockade on arginine and ADMA synthesis and metabolic pathways in fawn-hooded hypertensive rats.
    Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association, 2010, Volume: 25, Issue:11

    Topics: Amidohydrolases; Angiotensin II Type 1 Receptor Blockers; Animals; Arginine; Biphenyl Compounds; Citrulline; Hypertension; Irbesartan; Male; Metabolic Networks and Pathways; Nitric Oxide; Rats; Tetrazoles

2010
Melatonin prevents hypertension and increased asymmetric dimethylarginine in young spontaneous hypertensive rats.
    Journal of pineal research, 2010, Volume: 49, Issue:4

    Topics: Analysis of Variance; Animals; Arginine; Blood Pressure; Blotting, Western; Body Weight; Citrulline; Histocytochemistry; Hypertension; Male; Melatonin; Nitric Oxide; Nitric Oxide Synthase Type I; Nitric Oxide Synthase Type III; Organ Size; Oxidative Stress; Rats; Rats, Inbred SHR; Rats, Inbred WKY

2010
Aminoguanidine attenuates hypertension, whereas 7-nitroindazole exacerbates kidney damage in spontaneously hypertensive rats: the role of nitric oxide.
    European journal of pharmacology, 2013, Jan-15, Volume: 699, Issue:1-3

    Topics: Amidohydrolases; Animals; Arginine; Blood Pressure; Citrulline; Guanidines; Hypertension; Indazoles; Kidney Diseases; Male; Nitric Oxide; Nitric Oxide Synthase Type I; Rats; Rats, Inbred SHR; Sodium Chloride, Dietary; Up-Regulation

2013
High blood pressure enhances brain stem neuronal nitric oxide synthase activity in Dahl salt-sensitive rats.
    Clinical and experimental pharmacology & physiology, 2013, Volume: 40, Issue:3

    Topics: Animals; Arterial Pressure; Brain Stem; Citrulline; Disease Models, Animal; Enzyme Inhibitors; Hypertension; Immunohistochemistry; Male; Neurons; Nitric Oxide Synthase Type I; Rats; Rats, Inbred Dahl; Rats, Sprague-Dawley; Sodium Chloride, Dietary; Telemetry; Thiourea

2013
Role of nNOS in regulation of renal function in hypertensive Ren-2 transgenic rats.
    Physiological research, 2002, Volume: 51, Issue:6

    Topics: Analysis of Variance; Animals; Animals, Genetically Modified; Citrulline; Denervation; Enzyme Inhibitors; Gene Expression Regulation; Hypertension; Kidney; Male; Matched-Pair Analysis; Nitric Oxide Synthase; Nitric Oxide Synthase Type I; Rats; Rats, Inbred Strains; Renal Circulation; Renin; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Sympathetic Nervous System; Thiourea

2002
Brain neuronal nitric oxide synthase neuron-mediated sympathoinhibition is enhanced in hypertensive Dahl rats.
    Journal of hypertension, 2005, Volume: 23, Issue:4

    Topics: Animals; Arginine; Citrulline; Enzyme Inhibitors; Hypertension; Immunohistochemistry; Injections, Intraventricular; Male; Medulla Oblongata; Nerve Tissue Proteins; Neural Inhibition; Neurons; Nitric Oxide Synthase; Nitric Oxide Synthase Type I; Pedunculopontine Tegmental Nucleus; Periaqueductal Gray; Raphe Nuclei; Rats; Rats, Inbred Dahl; Solitary Nucleus; Sympathetic Nervous System; Thiourea

2005
Functional characterization of brain mitochondrial nitric oxide synthase during hypertension and aging.
    Amino acids, 2006, Volume: 30, Issue:1

    Topics: Aging; Animals; Arginine; Brain; Citrulline; Hypertension; Indazoles; Male; Mitochondria; Nitric Oxide Synthase; Nitric Oxide Synthase Type I; Oxygen Consumption; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Rats, Wistar

2006
Role of nitric oxide synthesis in salt-sensitive hypertension in Dahl/Rapp rats.
    Hypertension (Dallas, Tex. : 1979), 1993, Volume: 22, Issue:6

    Topics: Analysis of Variance; Animals; Arginine; Blood Pressure; Citrulline; Cyclic GMP; Dexamethasone; Disease Models, Animal; Homoarginine; Hypertension; Insulin; Male; Nitrates; Nitric Oxide; Ornithine; Rats; Rats, Inbred Strains

1993
Role of nitric oxide synthase inhibition in the acute hypertensive response to intracerebroventricular cadmium.
    British journal of pharmacology, 1998, Volume: 123, Issue:1

    Topics: Animals; Arginine; Blood Pressure; Brain Chemistry; Cadmium; Calcium Chloride; Citrulline; Enzyme Inhibitors; Heart Rate; Hypertension; Injections, Intraventricular; Male; Molsidomine; Nitric Oxide Synthase; Penicillamine; Rats; Rats, Wistar; S-Nitroso-N-Acetylpenicillamine; Vasodilator Agents

1998
Studies of arginine metabolism and salt sensitivity in the Dahl/Rapp rat models of hypertension.
    Molecular genetics and metabolism, 1998, Volume: 64, Issue:1

    Topics: Alanine; Animals; Arginine; Argininosuccinate Synthase; Blood Pressure; Body Weight; Citrulline; Disease Models, Animal; Hypertension; Kidney; Liver; Male; Ornithine; Rats; Sodium Chloride, Dietary; Urea

1998
Neuronal nitric oxide synthase-dependent afferent arteriolar function in angiotensin II-induced hypertension.
    Hypertension (Dallas, Tex. : 1979), 1999, Volume: 33, Issue:1 Pt 2

    Topics: Acetazolamide; Angiotensin II; Animals; Arterioles; Blood Pressure; Citrulline; Enzyme Inhibitors; Hypertension; Juxtaglomerular Apparatus; Kidney Medulla; Male; Microscopy, Video; Muscle, Smooth, Vascular; Nephrons; Nitric Oxide Synthase; Nitric Oxide Synthase Type I; Nitroarginine; Rats; Rats, Sprague-Dawley; Thiourea; Vasoconstriction; Vasodilation

1999
Increase in renal medullary nitric oxide synthase activity protects from norepinephrine-induced hypertension.
    Hypertension (Dallas, Tex. : 1979), 2000, Volume: 35, Issue:1 Pt 2

    Topics: Adrenergic alpha-Antagonists; Animals; Aorta; Arginine; Blood Pressure; Chromatography, High Pressure Liquid; Citrulline; Consciousness; Enzyme Activation; Hypertension; Infusions, Intravenous; Kidney Cortex; Kidney Medulla; Male; Nitric Oxide Synthase; Norepinephrine; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha-2; Sympathomimetics; Yohimbine

2000
Decreased plasma concentrations of L-hydroxy-arginine as a marker of reduced NO formation in patients with combined cardiovascular risk factors.
    The Journal of laboratory and clinical medicine, 2000, Volume: 135, Issue:5

    Topics: Adult; Aged; Arginine; Biomarkers; Cardiovascular Diseases; Chromatography, High Pressure Liquid; Citrulline; Female; Humans; Hyperglycemia; Hyperlipidemias; Hypertension; Male; Mass Spectrometry; Middle Aged; Nitric Oxide; Obesity; Risk Factors; Syndrome

2000
Effect of oral magnesium supplementation on blood pressure, platelet aggregation and calcium handling in deoxycorticosterone acetate induced hypertension in rats.
    Journal of hypertension, 2000, Volume: 18, Issue:7

    Topics: Administration, Oral; Animals; Antacids; Blood Platelets; Blood Pressure; Calcium; Citrulline; Desoxycorticosterone; Female; Hypertension; Intracellular Fluid; Magnesium; Magnesium Oxide; Male; Platelet Aggregation; Rats; Rats, Inbred WKY

2000
L-arginine partially reverses established adrenocorticotrophin-induced hypertension and nitric oxide deficiency in the rat.
    Blood pressure, 2000, Volume: 9, Issue:5

    Topics: Adrenocorticotropic Hormone; Amino Acids; Animals; Arginine; Citrulline; Cyclic GMP; Drug Evaluation; Hypertension; Male; Nitrates; Nitric Oxide; Nitrites; Random Allocation; Rats; Rats, Sprague-Dawley; Stereoisomerism

2000
Effect of arginine on cyclosporine-induced systemic hypertension after cardiac transplantation in the young.
    The American journal of cardiology, 2001, Apr-01, Volume: 87, Issue:7

    Topics: Adolescent; Adult; Arginine; Blood Pressure; Case-Control Studies; Chromatography, High Pressure Liquid; Citrulline; Cyclosporine; Echocardiography; Female; Heart Transplantation; Humans; Hypertension; Immunosuppressive Agents; Infusions, Intravenous; Male; Ventricular Function, Left

2001
L-arginine as an antihypertensive agent.
    Journal of cardiovascular pharmacology, 1992, Volume: 20 Suppl 12

    Topics: Antihypertensive Agents; Arginine; Blood Pressure; Cardiac Output; Citrulline; Cushing Syndrome; Humans; Hyperaldosteronism; Hypertension; Hypertension, Renovascular; Injections, Intravenous; Nitrates; Nitrites

1992
L-arginine abrogates salt-sensitive hypertension in Dahl/Rapp rats.
    The Journal of clinical investigation, 1991, Volume: 88, Issue:5

    Topics: Animals; Arginine; Blood Pressure; Citrulline; Cyclic GMP; Glomerular Filtration Rate; Hypertension; Nitric Oxide; omega-N-Methylarginine; Rats; Sodium Chloride

1991