citrulline and HbS Disease

citrulline has been researched along with HbS Disease in 13 studies

Research

Studies (13)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's7 (53.85)29.6817
2010's6 (46.15)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Bluck, L; Cox, SE; Kamuhabwa, A; Makani, J; Marealle, AI; Minzi, O; Prentice, AM; Sasi, P; Siervo, M; Soka, D; Wassel, S1
Barr, FE; Campbell, A; Cunningham, G; Darbari, D; Desai, J; Majumdar, S; Mashegu, H; Nickel, R; Shannon, NT; Summar, M; Tirona, R1
Cox, SE; Ellins, EA; Halcox, JP; Johnson, W; Kirkham, FJ; Luca Di Tanna, G; Makani, J; Marealle, AI; Newton, CR; Prentice, AM; Sasi, P; Soka, D1
De Simone, E; Di Iorio, B; Di Micco, L; La Manna, G1
Castro, O; Gladwin, MT; Harris, A; Hauser, KP; Kato, G; Little, JA; Machado, R; Maric, I; Martyr, SE; Morris, CR; Suh, JH; Taylor, J1
Blackwelder, WC; Hazen, SL; Kato, GJ; Machado, RF; Taylor, JG; Wang, Z1
McCarty, MF1
Brown, M; Duckworth, L; Froyen, M; Gauger, C; Kissoon, N; Murphy, S; Sandler, E; Sullivan, KJ1
Waugh, WH2
Dasgupta, T; Fabry, ME; Kaul, DK; Zhang, X1
Bayne, E; Duckworth, LJ; Freeman, B; Kissoon, N; Lima, JJ; Sandler, E; Sullivan, KJ; Sylvester, JE1
Fabry, ME; Nagel, RL; Romero, JR; Suzuka, SM1

Reviews

1 review(s) available for citrulline and HbS Disease

ArticleYear
[Protein carbamylation: what it is and why it concerns nephrologists].
    Giornale italiano di nefrologia : organo ufficiale della Societa italiana di nefrologia, 2018, Volume: 35, Issue:3

    Topics: Alzheimer Disease; Amino Acids; Amyloidosis; Anemia, Sickle Cell; Animals; Cardiovascular Diseases; Cataract; Chromatography, High Pressure Liquid; Citrulline; Clinical Trials as Topic; Cyanates; Follow-Up Studies; Humans; Kidney Failure, Chronic; Lipoproteins; Protein Carbamylation; Renal Dialysis; Tandem Mass Spectrometry; tau Proteins; Urea

2018

Trials

1 trial(s) available for citrulline and HbS Disease

ArticleYear
Effect of oral arginine supplementation on exhaled nitric oxide concentration in sickle cell anemia and acute chest syndrome.
    Journal of pediatric hematology/oncology, 2010, Volume: 32, Issue:7

    Topics: Acute Chest Syndrome; Acute Disease; Administration, Oral; Adolescent; Anemia, Sickle Cell; Arginine; Aspartic Acid; Breath Tests; Child; Citrulline; Female; Glutamic Acid; Humans; Male; Nitrates; Nitric Oxide; Nitrites; Ornithine; Young Adult

2010

Other Studies

11 other study(ies) available for citrulline and HbS Disease

ArticleYear
A pilot study of a non-invasive oral nitrate stable isotopic method suggests that arginine and citrulline supplementation increases whole-body NO production in Tanzanian children with sickle cell disease.
    Nitric oxide : biology and chemistry, 2018, 04-01, Volume: 74

    Topics: Administration, Oral; Anemia, Sickle Cell; Arginine; Child; Citrulline; Dietary Supplements; Female; Humans; Male; Nitrates; Nitric Oxide; Nitrogen Isotopes; Pilot Projects; Tanzania

2018
A phase 1 dose-finding study of intravenous L-citrulline in sickle cell disease: a potential novel therapy for sickle cell pain crisis.
    British journal of haematology, 2019, Volume: 184, Issue:4

    Topics: Adolescent; Adult; Anemia, Sickle Cell; Citrulline; Female; Humans; Male; Pain

2019
Ready-to-use food supplement, with or without arginine and citrulline, with daily chloroquine in Tanzanian children with sickle-cell disease: a double-blind, random order crossover trial.
    The Lancet. Haematology, 2018, Volume: 5, Issue:4

    Topics: Anemia, Sickle Cell; Arginine; Child; Chloroquine; Citrulline; Cross-Over Studies; Dietary Supplements; Double-Blind Method; Female; Humans; Male; Tanzania

2018
Hematologic, biochemical, and cardiopulmonary effects of L-arginine supplementation or phosphodiesterase 5 inhibition in patients with sickle cell disease who are on hydroxyurea therapy.
    European journal of haematology, 2009, Volume: 82, Issue:4

    Topics: Adult; Anemia, Sickle Cell; Arginase; Arginine; beta-Globins; Citrulline; Cyclic Nucleotide Phosphodiesterases, Type 5; Female; Fetal Hemoglobin; Humans; Hydroxyurea; Male; Middle Aged; Ornithine; Phosphodiesterase Inhibitors; Piperazines; Purines; Reticulocyte Count; Sildenafil Citrate; Sulfones

2009
Endogenous nitric oxide synthase inhibitors in sickle cell disease: abnormal levels and correlations with pulmonary hypertension, desaturation, haemolysis, organ dysfunction and death.
    British journal of haematology, 2009, Volume: 145, Issue:4

    Topics: Anemia, Sickle Cell; Arginine; Case-Control Studies; Citrulline; Follow-Up Studies; Hemolysis; Humans; Hypertension, Pulmonary; Kidney Diseases; Linear Models; Nitric Oxide Synthase; omega-N-Methylarginine; Oxygen; Proportional Hazards Models; Risk; Survival Rate

2009
Potential utility of full-spectrum antioxidant therapy, citrulline, and dietary nitrate in the management of sickle cell disease.
    Medical hypotheses, 2010, Volume: 74, Issue:6

    Topics: Anemia, Sickle Cell; Animals; Antioxidants; Arginine; Citrulline; Hemoglobins; Humans; Models, Biological; Nitrates; Nitric Oxide; Oxidative Stress; Vegetables

2010
Simplified method to assay total plasma peroxidase activity and ferriheme products in sickle cell anemia, with initial results in assessing clinical severity in a trial with citrulline therapy.
    Journal of pediatric hematology/oncology, 2003, Volume: 25, Issue:10

    Topics: Anemia, Sickle Cell; Blood Chemical Analysis; Child; Citrulline; Clinical Trials as Topic; Female; Hemin; Humans; Male; Peroxidase; Prognosis; Reproducibility of Results

2003
Arginine metabolism, pulmonary hypertension, and sickle cell disease.
    JAMA, 2005, Nov-16, Volume: 294, Issue:19

    Topics: Anemia, Sickle Cell; Arginase; Arginine; Citrulline; Dietary Supplements; Humans; Hypertension, Pulmonary

2005
Arginine therapy of transgenic-knockout sickle mice improves microvascular function by reducing non-nitric oxide vasodilators, hemolysis, and oxidative stress.
    American journal of physiology. Heart and circulatory physiology, 2008, Volume: 295, Issue:1

    Topics: Acetylcholine; Anemia, Sickle Cell; Animals; Arginine; Citrulline; Cyclooxygenase 2; Dinoprostone; Disease Models, Animal; Enzyme Inhibitors; Globins; Heme Oxygenase-1; Hemodynamics; Hemoglobins; Hemolysis; Humans; Membrane Proteins; Mice; Mice, Inbred C57BL; Mice, Knockout; Mice, Transgenic; Microcirculation; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Donors; Nitric Oxide Synthase Type II; Nitric Oxide Synthase Type III; Nitroprusside; Oxidative Stress; Tyrosine; Vasodilator Agents

2008
Low exhaled nitric oxide and a polymorphism in the NOS I gene is associated with acute chest syndrome.
    American journal of respiratory and critical care medicine, 2001, Dec-15, Volume: 164, Issue:12

    Topics: Acute Disease; Adolescent; Anemia, Sickle Cell; Arginine; Breath Tests; Child; Citrulline; Forced Expiratory Volume; Genotype; Humans; Lung Diseases; Nitrates; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type I; Nitrites; Polymorphism, Genetic; Syndrome; Trinucleotide Repeats; Vital Capacity

2001
Arginine supplementation of sickle transgenic mice reduces red cell density and Gardos channel activity.
    Blood, 2002, Feb-15, Volume: 99, Issue:4

    Topics: Anemia, Sickle Cell; Animals; Arginine; Citrulline; Disease Models, Animal; Erythrocyte Count; Erythrocytes; Hemoglobins; Humans; Kinetics; Mice; Mice, Transgenic; Oxygen; Potassium; Potassium Channels, Calcium-Activated

2002