citric acid, anhydrous has been researched along with Spasms, Infantile in 2 studies
Citric Acid: A key intermediate in metabolism. It is an acid compound found in citrus fruits. The salts of citric acid (citrates) can be used as anticoagulants due to their calcium chelating ability.
citric acid : A tricarboxylic acid that is propane-1,2,3-tricarboxylic acid bearing a hydroxy substituent at position 2. It is an important metabolite in the pathway of all aerobic organisms.
Spasms, Infantile: An epileptic syndrome characterized by the triad of infantile spasms, hypsarrhythmia, and arrest of psychomotor development at seizure onset. The majority present between 3-12 months of age, with spasms consisting of combinations of brief flexor or extensor movements of the head, trunk, and limbs. The condition is divided into two forms: cryptogenic (idiopathic) and symptomatic (secondary to a known disease process such as intrauterine infections; nervous system abnormalities; BRAIN DISEASES, METABOLIC, INBORN; prematurity; perinatal asphyxia; TUBEROUS SCLEROSIS; etc.). (From Menkes, Textbook of Child Neurology, 5th ed, pp744-8)
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (50.00) | 24.3611 |
| 2020's | 1 (50.00) | 2.80 |
| Authors | Studies |
|---|---|
| Kopel, JJ | 1 |
| Bhutia, YD | 1 |
| Sivaprakasam, S | 1 |
| Ganapathy, V | 1 |
| Bainbridge, MN | 1 |
| Cooney, E | 1 |
| Miller, M | 1 |
| Kennedy, AD | 1 |
| Wulff, JE | 1 |
| Donti, T | 1 |
| Jhangiani, SN | 1 |
| Gibbs, RA | 1 |
| Elsea, SH | 1 |
| Porter, BE | 1 |
| Graham, BH | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| SLC13A5 Deficiency: A Prospective Natural History Study - United States Only[NCT06144957] | 17 participants (Anticipated) | Observational | 2021-12-01 | Recruiting | |||
| SLC13A5 Deficiency: A Prospective Natural History Study - Remote Only (International)[NCT04681781] | 20 participants (Anticipated) | Observational | 2021-03-01 | Enrolling by invitation | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
1 review available for citric acid, anhydrous and Spasms, Infantile
| Article | Year |
|---|---|
Consequences of NaCT/SLC13A5/mINDY deficiency: good versus evil, separated only by the blood-brain barrier.
Topics: Animals; Blood-Brain Barrier; Bone and Bones; Citric Acid; Citric Acid Cycle; Dental Enamel; Diabete | 2021 |
1 other study available for citric acid, anhydrous and Spasms, Infantile
| Article | Year |
|---|---|
Analyses of SLC13A5-epilepsy patients reveal perturbations of TCA cycle.
Topics: Child; Citric Acid; Citric Acid Cycle; Exome Sequencing; Female; Humans; Infant, Newborn; Male; Mass | 2017 |
Analyses of SLC13A5-epilepsy patients reveal perturbations of TCA cycle.
Topics: Child; Citric Acid; Citric Acid Cycle; Exome Sequencing; Female; Humans; Infant, Newborn; Male; Mass | 2017 |
Analyses of SLC13A5-epilepsy patients reveal perturbations of TCA cycle.
Topics: Child; Citric Acid; Citric Acid Cycle; Exome Sequencing; Female; Humans; Infant, Newborn; Male; Mass | 2017 |
Analyses of SLC13A5-epilepsy patients reveal perturbations of TCA cycle.
Topics: Child; Citric Acid; Citric Acid Cycle; Exome Sequencing; Female; Humans; Infant, Newborn; Male; Mass | 2017 |