citric acid, anhydrous has been researched along with Shock, Septic in 13 studies
Citric Acid: A key intermediate in metabolism. It is an acid compound found in citrus fruits. The salts of citric acid (citrates) can be used as anticoagulants due to their calcium chelating ability.
citric acid : A tricarboxylic acid that is propane-1,2,3-tricarboxylic acid bearing a hydroxy substituent at position 2. It is an important metabolite in the pathway of all aerobic organisms.
Shock, Septic: Sepsis associated with HYPOTENSION or hypoperfusion despite adequate fluid resuscitation. Perfusion abnormalities may include but are not limited to LACTIC ACIDOSIS; OLIGURIA; or acute alteration in mental status.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Yucatan minipigs (8-15 kg) with induced septic shock underwent continuous hemodiafiltration with the CARPEDIEM™ pediatric hemodialysis system using regional citrate anticoagulation (RCA) with or without SCD (n = 5 per group)." | 1.91 | Immunomodulatory therapy using a pediatric dialysis system ameliorates septic shock in miniature pigs. ( Chan, G; Goldstein, SL; Humes, HD; Johnston, KA; Ketteler, SK; Pino, CJ, 2023) |
| "Thirty-seven children with septic shock admitted to the pediatric intensive care unit (PICU) of the First Affiliated Hospital of Gannan Medical University from July 2019 to September 2022 were enrolled as the research subjects." | 1.91 | [A comparative study of the effects of citrate and heparin anticoagulation on coagulation function and efficacy in children with septic shock undergoing continuous blood purification]. ( Deng, G; Lai, J; Luo, S; Ren, R; Zhong, X; Zhu, H, 2023) |
| "Septic shock is characterized by severe metabolic and hemodynamic alterations." | 1.56 | Feasibility and safety of combined cytokine adsorption and continuous veno-venous hemodialysis with regional citrate anticoagulation in patients with septic shock. ( Brandenburger, T; Dimski, T; Kindgen-Milles, D; Slowinski, T, 2020) |
| "Fifteen septic shock patients with acute kidney injury undergoing CPFA with RCA at target circuit citratemia of 6 mmol/L were treated with CPFA-haemofiltration in pure predilution (CPFA-HF predilution group, n = 5 patients), or predilution haemodiafiltration (CPFA-HDF predilution group, n = 5 patients) or pre- and postdilution haemofiltration (CPFA-HF pre/postdilution group, n = 5 patients)." | 1.42 | Citrate pharmacokinetics at high levels of circuit citratemia during coupled plasma filtration adsorption. ( Agostini, F; Biancone, L; Holló, Z; Mariano, F; Morselli, M; Stella, M, 2015) |
| "Twelve patients with septic shock on CVVHDF and citrate anticoagulation were studied ex vivo for citrate levels in systemic and circuit blood and in the ultrafiltrate (at 0, 0." | 1.37 | Blood and ultrafiltrate dosage of citrate as a useful and routine tool during continuous venovenous haemodiafiltration in septic shock patients. ( Bergamo, D; Dellavalle, A; Hollo, Z; Maio, M; Mariano, F; Morselli, M; Scella, S; Stella, M; Tetta, C; Triolo, G, 2011) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (7.69) | 29.6817 |
| 2010's | 7 (53.85) | 24.3611 |
| 2020's | 5 (38.46) | 2.80 |
| Authors | Studies |
|---|---|
| Chiao, C | 1 |
| Faust, H | 1 |
| Singh, T | 1 |
| Johnston, KA | 1 |
| Pino, CJ | 1 |
| Chan, G | 1 |
| Ketteler, SK | 1 |
| Goldstein, SL | 1 |
| Humes, HD | 1 |
| Zhong, X | 1 |
| Luo, S | 1 |
| Ren, R | 1 |
| Lai, J | 1 |
| Deng, G | 1 |
| Zhu, H | 1 |
| Mariano, F | 4 |
| Hollo', Z | 1 |
| Depetris, N | 1 |
| Malvasio, V | 1 |
| Mella, A | 1 |
| Bergamo, D | 2 |
| Pensa, A | 1 |
| Berardino, M | 1 |
| Stella, M | 4 |
| Biancone, L | 2 |
| Forfori, F | 2 |
| Brogi, E | 2 |
| Sidoti, A | 2 |
| Giraudini, M | 1 |
| Monti, G | 1 |
| Zarrillo, N | 1 |
| Cantaluppi, V | 1 |
| Ronco, C | 1 |
| Berlot, G | 1 |
| Falini, S | 1 |
| Negro, V | 1 |
| Agbedjro, A | 1 |
| Tomasini, A | 1 |
| Iscra, F | 1 |
| Bianco, F | 1 |
| Gerini, U | 1 |
| Boscutti, G | 1 |
| Vassallo, MC | 1 |
| Tartamella, F | 1 |
| Bhakta, P | 1 |
| Dimski, T | 1 |
| Brandenburger, T | 1 |
| Slowinski, T | 1 |
| Kindgen-Milles, D | 1 |
| Morselli, M | 2 |
| Holló, Z | 2 |
| Agostini, F | 1 |
| Morse, J | 1 |
| Collareta, M | 1 |
| Vetrugno, L | 1 |
| Giunta, F | 1 |
| Scella, S | 1 |
| Maio, M | 1 |
| Tetta, C | 2 |
| Dellavalle, A | 1 |
| Triolo, G | 2 |
| Devauchelle, P | 1 |
| Page, M | 1 |
| Brun, P | 1 |
| Ber, CE | 1 |
| Crozon, J | 1 |
| Baillon, JJ | 1 |
| Allaouchiche, B | 1 |
| Rimmelé, T | 1 |
| Biolino, P | 1 |
| Miletto, A | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Simplified Regional Citrate Anticoagulation Protocols for CVVH, CVVHDF and SLED Focused on the Prevention of RRT-related Hypophosphatemia and Optimization of Acid-base Balance: a Pilot Study[NCT03976440] | 30 participants (Anticipated) | Observational | 2019-06-01 | Active, not recruiting | |||
| Evaluation of a Simplified Protocol for Regional Citrate Anticoagulation in Continuous Venovenous Hemodiafiltration[NCT00583765] | 20 participants (Actual) | Observational | 2005-04-30 | Completed | |||
| HEpatic Regeneration With COupled Plasma Filtration and Adsorption for Liver Extracorporeal Detoxification[NCT03312036] | 12 participants (Actual) | Interventional | 2013-06-06 | Completed | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
1 trial available for citric acid, anhydrous and Shock, Septic
| Article | Year |
|---|---|
Regional citrate anticoagulation in critically ill patients treated with plasma filtration and adsorption.
Topics: Acute Kidney Injury; Adult; Aged; Anticoagulants; Burns; Calcium; Chemotherapy, Cancer, Regional Per | 2004 |
Regional citrate anticoagulation in critically ill patients treated with plasma filtration and adsorption.
Topics: Acute Kidney Injury; Adult; Aged; Anticoagulants; Burns; Calcium; Chemotherapy, Cancer, Regional Per | 2004 |
Regional citrate anticoagulation in critically ill patients treated with plasma filtration and adsorption.
Topics: Acute Kidney Injury; Adult; Aged; Anticoagulants; Burns; Calcium; Chemotherapy, Cancer, Regional Per | 2004 |
Regional citrate anticoagulation in critically ill patients treated with plasma filtration and adsorption.
Topics: Acute Kidney Injury; Adult; Aged; Anticoagulants; Burns; Calcium; Chemotherapy, Cancer, Regional Per | 2004 |
Regional citrate anticoagulation in critically ill patients treated with plasma filtration and adsorption.
Topics: Acute Kidney Injury; Adult; Aged; Anticoagulants; Burns; Calcium; Chemotherapy, Cancer, Regional Per | 2004 |
Regional citrate anticoagulation in critically ill patients treated with plasma filtration and adsorption.
Topics: Acute Kidney Injury; Adult; Aged; Anticoagulants; Burns; Calcium; Chemotherapy, Cancer, Regional Per | 2004 |
Regional citrate anticoagulation in critically ill patients treated with plasma filtration and adsorption.
Topics: Acute Kidney Injury; Adult; Aged; Anticoagulants; Burns; Calcium; Chemotherapy, Cancer, Regional Per | 2004 |
Regional citrate anticoagulation in critically ill patients treated with plasma filtration and adsorption.
Topics: Acute Kidney Injury; Adult; Aged; Anticoagulants; Burns; Calcium; Chemotherapy, Cancer, Regional Per | 2004 |
Regional citrate anticoagulation in critically ill patients treated with plasma filtration and adsorption.
Topics: Acute Kidney Injury; Adult; Aged; Anticoagulants; Burns; Calcium; Chemotherapy, Cancer, Regional Per | 2004 |
12 other studies available for citric acid, anhydrous and Shock, Septic
| Article | Year |
|---|---|
Regional citrate and systemic heparin are adequate to maintain filter half-life for COVID-19 patients on continuous renal replacement therapy.
Topics: Acute Kidney Injury; Adult; Anticoagulants; Citrates; Citric Acid; Continuous Renal Replacement Ther | 2022 |
Immunomodulatory therapy using a pediatric dialysis system ameliorates septic shock in miniature pigs.
Topics: Acute Kidney Injury; Animals; Anticoagulants; Citrates; Citric Acid; Immunomodulation; Renal Dialysi | 2023 |
[A comparative study of the effects of citrate and heparin anticoagulation on coagulation function and efficacy in children with septic shock undergoing continuous blood purification].
Topics: Anticoagulants; C-Reactive Protein; Case-Control Studies; Child; Citrates; Citric Acid; Fibrinolytic | 2023 |
Coupled-plasma filtration and adsorption for severe burn patients with septic shock and acute kidney injury treated with renal replacement therapy.
Topics: Acute Kidney Injury; Adolescent; Adult; Aged; Aged, 80 and over; Anticoagulants; Burns; Case-Control | 2020 |
Regional citrate-calcium anticoagulation during polymyxin-B hemoperfusion: A case series.
Topics: Aged; Anti-Bacterial Agents; Anticoagulants; Blood Coagulation; Citric Acid; Female; Hemoperfusion; | 2018 |
Regional Citrate Anticoagulation During Coupled Plasma Filtration and Adsorption May Increase Survival in Septic Shock.
Topics: Adsorption; Anticoagulants; Citrates; Citric Acid; Humans; Shock, Septic | 2019 |
Regional Citrate Anticoagulation During Coupled Plasma Filtration and Adsorption May Increase Survival in Septic Shock.
Topics: Adsorption; Anticoagulants; Citrates; Citric Acid; Humans; Shock, Septic | 2019 |
Feasibility and safety of combined cytokine adsorption and continuous veno-venous hemodialysis with regional citrate anticoagulation in patients with septic shock.
Topics: Acid-Base Equilibrium; Acute Kidney Injury; Adsorption; Aged; Anticoagulants; Citric Acid; Continuou | 2020 |
Citrate pharmacokinetics at high levels of circuit citratemia during coupled plasma filtration adsorption.
Topics: Acute Kidney Injury; Adsorption; Adult; Aged; Citric Acid; Female; Hemodiafiltration; Hemofiltration | 2015 |
Polymyxin B Direct Hemoperfusion Using Regional Citrate-Calcium Anticoagulation: A Case Report.
Topics: Aged; Anti-Bacterial Agents; Anticoagulants; Blood Coagulation; Calcium; Calcium Chloride; Citric Ac | 2016 |
Blood and ultrafiltrate dosage of citrate as a useful and routine tool during continuous venovenous haemodiafiltration in septic shock patients.
Topics: Adult; Aged; Aged, 80 and over; Citric Acid; Female; Hemodiafiltration; Hemodialysis Solutions; Huma | 2011 |
[Continuous haemodialysis with citrate anticoagulation in patients with liver failure: three cases].
Topics: Acute Kidney Injury; Anticoagulants; Calcium; Citric Acid; Fatal Outcome; Female; Hepatitis C; Human | 2012 |