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citric acid, anhydrous and Nephrocalcinosis

citric acid, anhydrous has been researched along with Nephrocalcinosis in 22 studies

Citric Acid: A key intermediate in metabolism. It is an acid compound found in citrus fruits. The salts of citric acid (citrates) can be used as anticoagulants due to their calcium chelating ability.
citric acid : A tricarboxylic acid that is propane-1,2,3-tricarboxylic acid bearing a hydroxy substituent at position 2. It is an important metabolite in the pathway of all aerobic organisms.

Nephrocalcinosis: A condition characterized by calcification of the renal tissue itself. It is usually seen in distal RENAL TUBULAR ACIDOSIS with calcium deposition in the DISTAL KIDNEY TUBULES and the surrounding interstitium. Nephrocalcinosis causes RENAL INSUFFICIENCY.

Research Excerpts

ExcerptRelevanceReference
"Treatment of ethylene glycol intoxication is based on specific inhibitors of alcohol dehydrogenase and hemodialysis in the most severe forms, and should be started promptly."5.39[Secondary hyperoxaluria and nephrocalcinosis due to ethylene glycol poisoning]. ( Harambat, J; Llanas, B; Missonnier, S; Monet, C; Rebouissoux, L; Richard, E, 2013)
" Magnesium deficiency caused pure calcium phosphate tissue deposits, containing no magnesium, but no deposition of calcium oxalate in the tubular lumen; tissue magnesium, calcium and phosphorus were increased, and there was marked potassium wastage via urine; despite mild hypercalcemia other signs of hyperparathyroidism were not found."3.70Reappraisal of the quantity and nature of renal calcifications and mineral metabolism in the magnesium-deficient rat. Effects of treatment with potassium citrate or the combination magnesium citrate and potassium citrate. ( Bergé, B; Dvorak, O; Markovic, M; Schmiedl, A; Schwille, PO, 1998)
" Sodium citrate therapy in a dosage of 0."2.72Does citrate prevent nephrocalcinosis in preterm neonates? ( Holscher, HC; Kist-van Holthe, J; Moerdijk, A; Schell-Feith, EA; van der Heijden, BJ; van Zwieten, PH; Zonderland, HM, 2006)
" Prevention of NC with (low) oral doses of citrate has not resulted in a significant decrease in the prevalence of NC; a higher citrate dosage deserves further study."2.46Nephrocalcinosis in preterm neonates. ( Kist-van Holthe, JE; Schell-Feith, EA; van der Heijden, AJ, 2010)
"Stone formation and nephrocalcinosis are both very common features of primary hyperoxaluria, yet the extent of each disease varies markedly between patients."1.42Nephrocalcinosis is a risk factor for kidney failure in primary hyperoxaluria. ( Bergstralh, EJ; Lieske, JC; Mehta, RA; Milliner, DS; Tang, X; Vrtiska, TJ, 2015)
"Treatment of ethylene glycol intoxication is based on specific inhibitors of alcohol dehydrogenase and hemodialysis in the most severe forms, and should be started promptly."1.39[Secondary hyperoxaluria and nephrocalcinosis due to ethylene glycol poisoning]. ( Harambat, J; Llanas, B; Missonnier, S; Monet, C; Rebouissoux, L; Richard, E, 2013)
"Nephrocalcinosis is not uncommon in preterm infants, and elevated urinary oxalate excretion is known to be one of the main risk factors."1.30Oxalate, citrate, and sulfate concentration in human milk compared with formula preparations: influence on urinary anion excretion. ( Bauerfeld, C; Hoppe, B; Langman, CB; Roth, B, 1998)
"A case of successful renal calculus dissolution by the combined treatment which consists of irrigation with ethylenediaminetetraacetic acid (EDTA), potassium citrate, and extracorporeal shock-wave lithotripsy (ESWL) is described here."1.27Combined treatment of medullary sponge kidney by EDTA potassium citrate and extracorporeal shock wave lithotripsy. ( Araki, T; Kinoshita, H; Nakatsuka, S; Tanaka, H; Ueda, H, 1988)

Research

Studies (22)

TimeframeStudies, this research(%)All Research%
pre-19904 (18.18)18.7374
1990's4 (18.18)18.2507
2000's9 (40.91)29.6817
2010's5 (22.73)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Monet, C1
Richard, E1
Missonnier, S1
Rebouissoux, L1
Llanas, B1
Harambat, J1
Cunha, NB1
Kawano, PR1
Padovani, CR1
Lima, Fde O1
Bernardes, S1
Magalhães, ES1
Amaro, CR1
Amaro, JL1
Tang, X1
Bergstralh, EJ1
Mehta, RA1
Vrtiska, TJ1
Milliner, DS1
Lieske, JC1
Schell-Feith, EA3
Kist-van Holthe, JE2
van der Heijden, AJ1
Adamcewicz, M1
Bearelly, D1
Porat, G1
Friedenberg, FK1
Sikora, P1
Roth, B2
Kribs, A1
Michalk, DV1
Hesse, A2
Hoppe, B3
Vashurina, TV1
Sergeeva, TV1
Chumakova, OV1
Tsygina, EN1
LAWRIE, TD1
HARRISON, HE1
HARRISON, HC1
White, MP1
Aladangady, N1
Rolton, HA1
McColl, JH1
Beattie, J1
Stapenhorst, L1
Sassen, R1
Beck, B1
Laube, N1
Moerdijk, A1
van Zwieten, PH2
Zonderland, HM2
Holscher, HC2
Kist-van Holthe, J1
van der Heijden, BJ2
Wolterbeek, R1
Veen, S1
Frolich, M1
Peru, H1
Akin, F1
Elmas, S1
Elmaci, AM1
Konrad, M1
Bauerfeld, C1
Langman, CB1
Schmiedl, A2
Schwille, PO2
Bergé, B1
Markovic, M1
Dvorak, O1
Weinstein, DA1
Somers, MJ1
Wolfsdorf, JI1
Bonucci, E1
Seitz, T1
Schwille, RM1
Manoharan, M1
Kluka, V1
Murphy, JL1
Mendoza, SA1
Nakatsuka, S1
Kinoshita, H1
Ueda, H1
Araki, T1
Tanaka, H1
Ogawa, Y1
Tanaka, T1
Yamaguchi, K1
Morozumi, M1
Kitagawa, R1

Clinical Trials (2)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Comparison of Colon Preparation With 2-Litre Polyethylene Glycol (PEG) Split-dose in Combination With Lubiprostone Versus 4-Litre Polyethylene Glycol (PEG) Split-dose: a Randomized Controlled Trial[NCT04138004]Phase 4140 participants (Actual)Interventional2019-12-01Completed
[NCT00249951]Phase 380 participants (Actual)Interventional2005-11-30Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

2 reviews available for citric acid, anhydrous and Nephrocalcinosis

ArticleYear
Nephrocalcinosis in preterm neonates.
    Pediatric nephrology (Berlin, Germany), 2010, Volume: 25, Issue:2

    Topics: Animals; Calcium Oxalate; Citric Acid; Disease Models, Animal; Female; Gestational Age; Humans; Infa

2010
Mechanism of action and toxicities of purgatives used for colonoscopy preparation.
    Expert opinion on drug metabolism & toxicology, 2011, Volume: 7, Issue:1

    Topics: Ascorbic Acid; Calcium Phosphates; Cathartics; Citric Acid; Colonic Neoplasms; Colonoscopy; Humans;

2011

Trials

1 trial available for citric acid, anhydrous and Nephrocalcinosis

ArticleYear
Does citrate prevent nephrocalcinosis in preterm neonates?
    Pediatric nephrology (Berlin, Germany), 2006, Volume: 21, Issue:12

    Topics: Citric Acid; Humans; Infant, Newborn; Infant, Premature; Nephrocalcinosis

2006

Other Studies

19 other studies available for citric acid, anhydrous and Nephrocalcinosis

ArticleYear
[Secondary hyperoxaluria and nephrocalcinosis due to ethylene glycol poisoning].
    Archives de pediatrie : organe officiel de la Societe francaise de pediatrie, 2013, Volume: 20, Issue:8

    Topics: Accidents, Home; Acidosis; Calcium Oxalate; Child, Preschool; Citric Acid; Ethylene Glycol; Fluid Th

2013
Nephrocalcinosis induced by hyperoxaluria in rats.
    Acta cirurgica brasileira, 2013, Volume: 28, Issue:7

    Topics: Animals; Calcium; Citric Acid; Hyperoxaluria; Kidney; Male; Nephrocalcinosis; Oxalates; Random Alloc

2013
Nephrocalcinosis is a risk factor for kidney failure in primary hyperoxaluria.
    Kidney international, 2015, Volume: 87, Issue:3

    Topics: Adolescent; Adult; Age of Onset; Child; Child, Preschool; Citric Acid; Female; Humans; Hyperoxaluria

2015
Hypocitraturia is one of the major risk factors for nephrocalcinosis in very low birth weight (VLBW) infants.
    Kidney international, 2003, Volume: 63, Issue:6

    Topics: Calcium; Citric Acid; Female; Humans; Infant, Newborn; Infant, Newborn, Diseases; Infant, Premature;

2003
[Distal renal tubular acidosis complicated by medullary cysts].
    Terapevticheskii arkhiv, 2003, Volume: 75, Issue:6

    Topics: Acidosis, Renal Tubular; Child; Citric Acid; Diagnosis, Differential; Humans; Kidney Diseases, Cysti

2003
Nephrocalcinosis: report of a case showing an apparent response to citrate therapy.
    Glasgow medical journal, 1954, Volume: 35, Issue:6

    Topics: Calcinosis; Citrates; Citric Acid; Humans; Kidney Diseases; Nephrocalcinosis

1954
Inhibition of urine citrate excretion and the production of renal calcinosis in the rat by acetazoleamide (diamox) administration.
    The Journal of clinical investigation, 1955, Volume: 34, Issue:11

    Topics: Acetazolamide; Animals; Calcinosis; Citrates; Citric Acid; Diuretics; Hydro-Lyases; Kidney Diseases;

1955
Urinary citrate in preterm and term babies.
    Early human development, 2005, Volume: 81, Issue:2

    Topics: Calcium; Citric Acid; Creatinine; Female; Humans; Infant, Newborn; Infant, Premature; Male; Nephroca

2005
Hypocitraturia as a risk factor for nephrocalcinosis after kidney transplantation.
    Pediatric nephrology (Berlin, Germany), 2005, Volume: 20, Issue:5

    Topics: Adolescent; Adult; Calcineurin Inhibitors; Calcium Oxalate; Child; Citric Acid; Cyclosporine; Female

2005
Is nephrocalcinosis in preterm neonates harmful for long-term blood pressure and renal function?
    Pediatrics, 2007, Volume: 119, Issue:3

    Topics: Blood Pressure; Calcium; Child; Child Development; Citric Acid; Female; Follow-Up Studies; Humans; I

2007
Familial hypomagnesemia with hypercalciuria and nephrocalcinosis: report of three Turkish siblings.
    Pediatric nephrology (Berlin, Germany), 2008, Volume: 23, Issue:6

    Topics: Child; Citric Acid; Claudins; Homozygote; Humans; Hypercalciuria; Infant; Magnesium; Male; Membrane

2008
Oxalate, citrate, and sulfate concentration in human milk compared with formula preparations: influence on urinary anion excretion.
    Journal of pediatric gastroenterology and nutrition, 1998, Volume: 27, Issue:4

    Topics: Anions; Citric Acid; Female; Humans; Infant Food; Infant, Newborn; Milk, Human; Nephrocalcinosis; Ox

1998
Reappraisal of the quantity and nature of renal calcifications and mineral metabolism in the magnesium-deficient rat. Effects of treatment with potassium citrate or the combination magnesium citrate and potassium citrate.
    Urologia internationalis, 1998, Volume: 61, Issue:2

    Topics: Animals; Calcium; Calcium Phosphates; Cathartics; Citric Acid; Disease Models, Animal; Diuretics; Dr

1998
Decreased urinary citrate excretion in type 1a glycogen storage disease.
    The Journal of pediatrics, 2001, Volume: 138, Issue:3

    Topics: Adolescent; Adult; Calcium; Child; Child, Preschool; Citric Acid; Female; Glomerular Filtration Rate

2001
Renal cortical calcification in syngeneic intact rats and those receiving an infrarenal thoracic aortic graft: possible etiological roles of endothelin, nitrate and minerals, and different preventive effects of long-term oral treatment with magnesium, cit
    Urological research, 2001, Volume: 29, Issue:4

    Topics: Alkalies; Animals; Aorta; Aorta, Thoracic; Citric Acid; Endothelins; Kidney; Kidney Cortex; Magnesiu

2001
Hypocitraturic and hypercalciuric renal tubular acidosis with nephrocalcinosis in a 4-year-old boy.
    International urology and nephrology, 1990, Volume: 22, Issue:5

    Topics: Acidosis, Renal Tubular; Antacids; Calcium Metabolism Disorders; Carbon Dioxide; Child, Preschool; C

1990
Decreased urinary citrate in premature infants with lung disease.
    Child nephrology and urology, 1990, Volume: 10, Issue:2

    Topics: Citrates; Citric Acid; Humans; Infant, Newborn; Infant, Premature; Nephrocalcinosis; Respiration, Ar

1990
Combined treatment of medullary sponge kidney by EDTA potassium citrate and extracorporeal shock wave lithotripsy.
    European urology, 1988, Volume: 14, Issue:4

    Topics: Adult; Citrates; Citric Acid; Edetic Acid; Humans; Kidney Calculi; Lithotripsy; Male; Medullary Spon

1988
Effects of sodium citrate, potassium citrate, and citric acid in preventing experimental calcium oxalate urolithiasis in rats.
    Hinyokika kiyo. Acta urologica Japonica, 1987, Volume: 33, Issue:11

    Topics: Animals; Calcium Oxalate; Citrates; Citric Acid; Glycolates; Nephrocalcinosis; Rats; Rats, Inbred St

1987