citric acid, anhydrous has been researched along with Magnesium Deficiency in 10 studies
Citric Acid: A key intermediate in metabolism. It is an acid compound found in citrus fruits. The salts of citric acid (citrates) can be used as anticoagulants due to their calcium chelating ability.
citric acid : A tricarboxylic acid that is propane-1,2,3-tricarboxylic acid bearing a hydroxy substituent at position 2. It is an important metabolite in the pathway of all aerobic organisms.
Magnesium Deficiency: A nutritional condition produced by a deficiency of magnesium in the diet, characterized by anorexia, nausea, vomiting, lethargy, and weakness. Symptoms are paresthesias, muscle cramps, irritability, decreased attention span, and mental confusion, possibly requiring months to appear. Deficiency of body magnesium can exist even when serum values are normal. In addition, magnesium deficiency may be organ-selective, since certain tissues become deficient before others. (Harrison's Principles of Internal Medicine, 12th ed, p1936)
| Excerpt | Relevance | Reference |
|---|---|---|
| "The study was performed to ascertain the value of potassium magnesium citrate, magnesium citrate, and potassium citrate in overcoming thiazide-induced hypokalemia and magnesium loss." | 9.09 | Effect of potassium magnesium citrate on thiazide-induced hypokalemia and magnesium loss. ( Pak, CY; Ruml, LA, 1999) |
| "The purpose of this study was to compare the efficacy of three dosages of potassium-magnesium citrate in overcoming thiazide-induced hypokalemia and magnesium loss and increasing urinary pH and citrate." | 9.09 | Effect of varying doses of potassium-magnesium citrate on thiazide-induced hypokalemia and magnesium loss. ( Gonzalez, G; Pak, CY; Ruml, LA; Taylor, R; Wuermser, LA, 1999) |
| "The study was performed to ascertain the value of potassium magnesium citrate, magnesium citrate, and potassium citrate in overcoming thiazide-induced hypokalemia and magnesium loss." | 5.09 | Effect of potassium magnesium citrate on thiazide-induced hypokalemia and magnesium loss. ( Pak, CY; Ruml, LA, 1999) |
| "The purpose of this study was to compare the efficacy of three dosages of potassium-magnesium citrate in overcoming thiazide-induced hypokalemia and magnesium loss and increasing urinary pH and citrate." | 5.09 | Effect of varying doses of potassium-magnesium citrate on thiazide-induced hypokalemia and magnesium loss. ( Gonzalez, G; Pak, CY; Ruml, LA; Taylor, R; Wuermser, LA, 1999) |
| " Magnesium deficiency caused pure calcium phosphate tissue deposits, containing no magnesium, but no deposition of calcium oxalate in the tubular lumen; tissue magnesium, calcium and phosphorus were increased, and there was marked potassium wastage via urine; despite mild hypercalcemia other signs of hyperparathyroidism were not found." | 3.70 | Reappraisal of the quantity and nature of renal calcifications and mineral metabolism in the magnesium-deficient rat. Effects of treatment with potassium citrate or the combination magnesium citrate and potassium citrate. ( Bergé, B; Dvorak, O; Markovic, M; Schmiedl, A; Schwille, PO, 1998) |
| "Preterm birth is the leading cause of infant mortality globally, including Brazil." | 2.79 | The BRAzil MAGnesium (BRAMAG) trial: a randomized clinical trial of oral magnesium supplementation in pregnancy for the prevention of preterm birth and perinatal and maternal morbidity. ( Alves, JG; de Araújo, CA; Guimarães, AC; Pontes, IE; Ray, JG, 2014) |
| " Finally, parenteral Mg was discontinued as the dosage of oral Mg supplementation reached a level of 90 mg/kg/d elemental Mg citrate, without any gastrointestinal side effects." | 1.33 | Successful management of primary hypomagnesaemia with high-dose oral magnesium citrate: a case report. ( Bircan, I; Dursun, O; Karaguzel, G; Turkkahraman, D, 2006) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 4 (40.00) | 18.2507 |
| 2000's | 2 (20.00) | 29.6817 |
| 2010's | 4 (40.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Quiñones, H | 1 |
| Hamdi, T | 1 |
| Sakhaee, K | 1 |
| Pasch, A | 1 |
| Moe, OW | 1 |
| Pak, CYC | 1 |
| Alves, JG | 1 |
| de Araújo, CA | 1 |
| Pontes, IE | 1 |
| Guimarães, AC | 1 |
| Ray, JG | 1 |
| Mander, R | 1 |
| Brain, M | 1 |
| Anderson, M | 1 |
| Parkes, S | 1 |
| Fowler, P | 1 |
| Reungjui, S | 1 |
| Prasongwatana, V | 1 |
| Premgamone, A | 1 |
| Tosukhowong, P | 1 |
| Jirakulsomchok, S | 1 |
| Sriboonlue, P | 1 |
| Bircan, I | 1 |
| Turkkahraman, D | 1 |
| Dursun, O | 1 |
| Karaguzel, G | 1 |
| Paccalin, J | 1 |
| Gelas, B | 1 |
| Herbrecht, F | 1 |
| Torres, C | 1 |
| Chevallier, T | 1 |
| Micheletti, MC | 1 |
| Schmiedl, A | 1 |
| Schwille, PO | 1 |
| Bergé, B | 1 |
| Markovic, M | 1 |
| Dvorak, O | 1 |
| Ruml, LA | 2 |
| Pak, CY | 2 |
| Gonzalez, G | 1 |
| Taylor, R | 1 |
| Wuermser, LA | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| A Randomized Clinical Trial of Oral Magnesium Supplementation In Pregnancy for the Prevention of Preterm Birth and Perinatal and Maternal Morbidity[NCT02032186] | Phase 3 | 3,000 participants (Actual) | Interventional | 2014-03-31 | Completed | ||
| Efficiency and Safety of Magnesium Lactate Administration in the Reduction of Gestational Diabetes Incidence.[NCT04037098] | 0 participants (Actual) | Interventional | 2022-07-31 | Withdrawn (stopped due to Lack of financial support and pandemia) | |||
| Preventing Metabolic Side Effects of Thiazide Diuretics With KMgCitrate[NCT02665117] | 61 participants (Actual) | Interventional | 2015-01-31 | Completed | |||
| A Multi-Site Placebo-Controlled Randomized Double-Blind Study to Evaluate the Efficacy and Safety of Using MPC-5971 as Adjuvant Therapy in Subjects Undergoing Shock Wave Lithotripsy[NCT00860093] | Phase 2 | 135 participants (Actual) | Interventional | 2010-04-30 | Terminated (stopped due to Sponsor Corporate Business Decision) | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
Will be measured using hepatic magnetic resonance imaging at baseline and at week 16 (NCT02665117)
Timeframe: baseline to week 16
| Intervention | percent (Mean) |
|---|---|
| KMgCit + Chlorthalidone | 0.31 |
| KCl + Chlorthalidone | 1.59 |
Fasting plasma glucose was measured from venous blood sample at week 4 and week 16 (NCT02665117)
Timeframe: week 4 and week 16
| Intervention | mg/dL (Mean) |
|---|---|
| KMgCit + Chlorthalidone | -5.6 |
| KCl + Chlorthalidone | 2.3 |
Will be measured from venous blood sample from week 4 to week 16 (NCT02665117)
Timeframe: week 4 to week 16
| Intervention | pg/ml (Mean) |
|---|---|
| KMgCit + Chlorthalidone | 38.1 |
| KCl + Chlorthalidone | 13.6 |
Will be measured using magnetic resonance imaging at baseline and at week 16 (NCT02665117)
Timeframe: baseline to week 16
| Intervention | mM (Mean) |
|---|---|
| KMgCit + Chlorthalidone | -0.01 |
| KCl + Chlorthalidone | 0.02 |
1 review available for citric acid, anhydrous and Magnesium Deficiency
| Article | Year |
|---|---|
Magnesium: the relevance of research.
Topics: Citric Acid; Dietary Supplements; Female; Humans; Magnesium Deficiency; Midwifery; Nursing Methodolo | 2014 |
5 trials available for citric acid, anhydrous and Magnesium Deficiency
| Article | Year |
|---|---|
Control of metabolic predisposition to cardiovascular complications of chronic kidney disease by effervescent calcium magnesium citrate: a feasibility study.
Topics: Acid-Base Equilibrium; Acidosis; Aged; Bicarbonates; Biomarkers; Calcium Citrate; Cardiovascular Dis | 2019 |
The BRAzil MAGnesium (BRAMAG) trial: a randomized clinical trial of oral magnesium supplementation in pregnancy for the prevention of preterm birth and perinatal and maternal morbidity.
Topics: Abruptio Placentae; Administration, Oral; Adolescent; Adult; Brazil; Citric Acid; Dietary Supplement | 2014 |
The BRAzil MAGnesium (BRAMAG) trial: a randomized clinical trial of oral magnesium supplementation in pregnancy for the prevention of preterm birth and perinatal and maternal morbidity.
Topics: Abruptio Placentae; Administration, Oral; Adolescent; Adult; Brazil; Citric Acid; Dietary Supplement | 2014 |
The BRAzil MAGnesium (BRAMAG) trial: a randomized clinical trial of oral magnesium supplementation in pregnancy for the prevention of preterm birth and perinatal and maternal morbidity.
Topics: Abruptio Placentae; Administration, Oral; Adolescent; Adult; Brazil; Citric Acid; Dietary Supplement | 2014 |
The BRAzil MAGnesium (BRAMAG) trial: a randomized clinical trial of oral magnesium supplementation in pregnancy for the prevention of preterm birth and perinatal and maternal morbidity.
Topics: Abruptio Placentae; Administration, Oral; Adolescent; Adult; Brazil; Citric Acid; Dietary Supplement | 2014 |
[Acceptability and short-term tolerance to an orally administered new formulation of magnesium (TX 1341) compared to that of a reference magnesium].
Topics: Administration, Oral; Chemistry, Pharmaceutical; Citric Acid; Humans; Lactates; Magnesium; Magnesium | 1998 |
Effect of potassium magnesium citrate on thiazide-induced hypokalemia and magnesium loss.
Topics: Adult; Citrates; Citric Acid; Diuretics; Drug Combinations; Female; Humans; Hydrochlorothiazide; Hyp | 1999 |
Effect of potassium magnesium citrate on thiazide-induced hypokalemia and magnesium loss.
Topics: Adult; Citrates; Citric Acid; Diuretics; Drug Combinations; Female; Humans; Hydrochlorothiazide; Hyp | 1999 |
Effect of potassium magnesium citrate on thiazide-induced hypokalemia and magnesium loss.
Topics: Adult; Citrates; Citric Acid; Diuretics; Drug Combinations; Female; Humans; Hydrochlorothiazide; Hyp | 1999 |
Effect of potassium magnesium citrate on thiazide-induced hypokalemia and magnesium loss.
Topics: Adult; Citrates; Citric Acid; Diuretics; Drug Combinations; Female; Humans; Hydrochlorothiazide; Hyp | 1999 |
Effect of varying doses of potassium-magnesium citrate on thiazide-induced hypokalemia and magnesium loss.
Topics: Adult; Benzothiadiazines; Citrates; Citric Acid; Diuretics; Dose-Response Relationship, Drug; Drug C | 1999 |
4 other studies available for citric acid, anhydrous and Magnesium Deficiency
| Article | Year |
|---|---|
Magnesium flux during continuous venovenous haemodiafiltration with heparin and citrate anticoagulation.
Topics: Adult; Aged; Anticoagulants; Area Under Curve; Citric Acid; Dialysis Solutions; Female; Half-Life; H | 2012 |
Magnesium status of patients with renal stones and its effect on urinary citrate excretion.
Topics: Adult; Case-Control Studies; Citric Acid; Dietary Supplements; Female; Humans; Kidney Calculi; Magne | 2002 |
Successful management of primary hypomagnesaemia with high-dose oral magnesium citrate: a case report.
Topics: Administration, Oral; Calcium; Child, Preschool; Citric Acid; Female; Humans; Infant; Magnesium Defi | 2006 |
Reappraisal of the quantity and nature of renal calcifications and mineral metabolism in the magnesium-deficient rat. Effects of treatment with potassium citrate or the combination magnesium citrate and potassium citrate.
Topics: Animals; Calcium; Calcium Phosphates; Cathartics; Citric Acid; Disease Models, Animal; Diuretics; Dr | 1998 |