citric acid, anhydrous has been researched along with Liver Failure in 23 studies
Citric Acid: A key intermediate in metabolism. It is an acid compound found in citrus fruits. The salts of citric acid (citrates) can be used as anticoagulants due to their calcium chelating ability.
citric acid : A tricarboxylic acid that is propane-1,2,3-tricarboxylic acid bearing a hydroxy substituent at position 2. It is an important metabolite in the pathway of all aerobic organisms.
Liver Failure: Severe inability of the LIVER to perform its normal metabolic functions, as evidenced by severe JAUNDICE and abnormal serum levels of AMMONIA; BILIRUBIN; ALKALINE PHOSPHATASE; ASPARTATE AMINOTRANSFERASE; LACTATE DEHYDROGENASES; and albumin/globulin ratio. (Blakiston's Gould Medical Dictionary, 4th ed)
| Excerpt | Relevance | Reference |
|---|---|---|
| "A 63-year-old male with lactic acidosis secondary to fialuridine-induced liver failure underwent seven plasma exchanges while awaiting orthotopic liver transplantation." | 3.69 | Falsely low calcium measurements after high volume plasma exchange in a patient with liver failure. ( Miller, JP; Mintz, PD, 1994) |
| "Regional citrate anticoagulation seems to be a safe anticoagulation method in liver failure patients underwent CRRT and could yield a favorable filter lifespan." | 2.61 | Safety and efficacy of regional citrate anticoagulation for continuous renal replacement therapy in liver failure patients: a systematic review and meta-analysis. ( Bai, M; Chen, X; Li, L; Sun, S; Yu, Y; Zhang, W; Zhao, L, 2019) |
| "The decrease in hepatic encephalopathy (HE) and the serum levels of bilirubin and ammonia were measured to determine efficacy." | 1.56 | Single-Pass Albumin Dialysis in the Treatment of Children with Liver Failure. ( Balmer, S; Bufler, P; Gratopp, A; Henning, S; Holle, J; Müller, D; Rosenfeld, L; Varnholt, V, 2020) |
| "Liver failure is a rapidly progressive condition with a high mortality rate." | 1.56 | [Research progress of the application of regional citrate anticoagulation in artificial liver to treat liver failure]. ( Bai, L; Ma, YJ; Tang, H, 2020) |
| " Safety was assessed by adverse events: bleeding, hemodynamic instability, arrhythmias, unplanned treatment discontinuation." | 1.51 | The Safety and Efficacy of Regional Citrate Anticoagulation in Albumin-Assisted Liver Dialysis for Extracorporeal Liver Support in Pediatric Patients. ( Arikan, AA; Desai, MS; Lion, RP; Srivaths, P; Tufan Pekkucuksen, N, 2019) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (4.35) | 18.2507 |
| 2000's | 5 (21.74) | 29.6817 |
| 2010's | 9 (39.13) | 24.3611 |
| 2020's | 8 (34.78) | 2.80 |
| Authors | Studies |
|---|---|
| Botan, E | 1 |
| Durak, A | 1 |
| Gün, E | 1 |
| Gurbanov, A | 1 |
| Balaban, B | 1 |
| Kahveci, F | 1 |
| Özen, H | 1 |
| Uçmak, H | 1 |
| Aycan, F | 1 |
| Kendirli, T | 1 |
| Cappoli, A | 1 |
| Labbadia, R | 1 |
| Antonucci, L | 1 |
| Bottari, G | 1 |
| Rossetti, E | 1 |
| Guzzo, I | 1 |
| Holle, J | 1 |
| Gratopp, A | 1 |
| Balmer, S | 1 |
| Varnholt, V | 1 |
| Henning, S | 1 |
| Bufler, P | 1 |
| Müller, D | 1 |
| Rosenfeld, L | 1 |
| Honore, PM | 2 |
| Mugisha, A | 1 |
| David, C | 1 |
| Attou, R | 1 |
| Redant, S | 1 |
| Gallerani, A | 1 |
| De Bels, D | 1 |
| Yu, Y | 2 |
| Bai, M | 2 |
| Ma, F | 1 |
| Zhang, W | 2 |
| Li, Y | 1 |
| Zhao, L | 2 |
| Li, L | 3 |
| Zhou, M | 1 |
| Sun, S | 2 |
| Ma, YJ | 1 |
| Bai, L | 2 |
| Tang, H | 2 |
| Ma, Y | 1 |
| Chen, F | 1 |
| Liu, C | 1 |
| Xu, Y | 1 |
| Wang, M | 1 |
| Zhou, T | 1 |
| Lei, X | 1 |
| Feng, P | 1 |
| Strobl, K | 1 |
| Harm, S | 1 |
| Fichtinger, U | 1 |
| Schildböck, C | 1 |
| Hartmann, J | 1 |
| Lion, RP | 1 |
| Tufan Pekkucuksen, N | 1 |
| Srivaths, P | 1 |
| Desai, MS | 1 |
| Arikan, AA | 1 |
| Ning, QQ | 1 |
| Meng, QH | 1 |
| Zhu, YK | 1 |
| Chen, X | 2 |
| Sponholz, C | 1 |
| Settmacher, U | 1 |
| Bauer, M | 1 |
| Kortgen, A | 1 |
| Slowinski, T | 1 |
| Morgera, S | 1 |
| Joannidis, M | 1 |
| Henneberg, T | 1 |
| Stocker, R | 1 |
| Helset, E | 1 |
| Andersson, K | 1 |
| Wehner, M | 1 |
| Kozik-Jaromin, J | 1 |
| Brett, S | 1 |
| Hasslacher, J | 1 |
| Stover, JF | 1 |
| Peters, H | 1 |
| Neumayer, HH | 1 |
| Kindgen-Milles, D | 1 |
| Jacobs, R | 1 |
| Hendrickx, I | 1 |
| De Waele, E | 1 |
| Van Gorp, V | 1 |
| Spapen, HD | 1 |
| Meijers, B | 1 |
| Laleman, W | 1 |
| Vermeersch, P | 1 |
| Nevens, F | 1 |
| Wilmer, A | 1 |
| Evenepoel, P | 1 |
| Schultheiß, C | 1 |
| Saugel, B | 1 |
| Phillip, V | 1 |
| Thies, P | 1 |
| Noe, S | 1 |
| Mayr, U | 1 |
| Haller, B | 1 |
| Einwächter, H | 1 |
| Schmid, RM | 1 |
| Huber, W | 1 |
| Patel, S | 1 |
| Wendon, J | 1 |
| Abe, T | 2 |
| Kobata, H | 1 |
| Hanba, Y | 1 |
| Kitabata, Y | 1 |
| Narukawa, N | 1 |
| Hasegawa, H | 1 |
| Fukagawa, M | 1 |
| Nakae, H | 1 |
| Yonekawa, C | 1 |
| Moon, S | 1 |
| Tajimi, K | 1 |
| Krisper, P | 1 |
| Stauber, RE | 1 |
| Miller, JP | 1 |
| Mintz, PD | 1 |
| Meier-Kriesche, HU | 1 |
| Gitomer, J | 1 |
| Finkel, K | 1 |
| DuBose, T | 1 |
| Feng, J | 1 |
| Li, X | 1 |
| Pei, F | 1 |
| Li, S | 1 |
| Nie, Y | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Prismaflex Therapeutic Plasma Exchange: Evaluation of Complication Rates Using Filter vs. Centrifuge and Heparin vs. Citrate Anticoagulation[NCT04351438] | 108 participants (Actual) | Observational | 2012-01-31 | Active, not recruiting | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
3 reviews available for citric acid, anhydrous and Liver Failure
| Article | Year |
|---|---|
[Advances in the application of regional citrate anticoagulation for continuous renal replacement therapy in patients with liver failure].
Topics: Acute Kidney Injury; Anticoagulants; Citrates; Citric Acid; Humans; Liver Failure; Renal Replacement | 2018 |
Safety and efficacy of regional citrate anticoagulation for continuous renal replacement therapy in liver failure patients: a systematic review and meta-analysis.
Topics: Acid-Base Equilibrium; Adult; Anticoagulants; Citric Acid; Hemorrhage; Humans; Liver Failure; Renal | 2019 |
Technology insight: artificial extracorporeal liver support--how does Prometheus compare with MARS?
Topics: Anticoagulants; Cholestasis; Citric Acid; Equipment Design; Heparin; Humans; Liver Failure; Pruritus | 2007 |
2 trials available for citric acid, anhydrous and Liver Failure
| Article | Year |
|---|---|
A prospective randomized open-label crossover trial of regional citrate anticoagulation vs. anticoagulation free liver dialysis by the Molecular Adsorbents Recirculating System.
Topics: Adsorption; Adult; Aged; Anticoagulants; Citric Acid; Cross-Over Studies; Extracorporeal Circulation | 2012 |
Study of plasma exchange for liver failure: beneficial and harmful effects.
Topics: Acetates; Aged; Calcium; Citric Acid; Combined Modality Therapy; Female; Humans; Liver Failure; Male | 2004 |
18 other studies available for citric acid, anhydrous and Liver Failure
| Article | Year |
|---|---|
Continuous Renal Replacement Therapy with Regional Citrate Anticoagulation in Children with Liver Dysfunction/Failure.
Topics: Anticoagulants; Calcium; Child; Citrates; Citric Acid; Continuous Renal Replacement Therapy; Female; | 2022 |
A simplified protocol of regional citrate anticoagulation with phosphate-containing solutions in infants and children treated with continuous kidney replacement therapy.
Topics: Acute Kidney Injury; Adult; Anticoagulants; Child; Citrates; Citric Acid; Critical Illness; Hemofilt | 2023 |
Single-Pass Albumin Dialysis in the Treatment of Children with Liver Failure.
Topics: Adolescent; Anticoagulants; Child; Child, Preschool; Citric Acid; Female; Heparin; Hepatic Encephalo | 2020 |
In severe liver disease, citrate can be used safely: the question remains-by which mechanism.
Topics: Anticoagulants; Citrates; Citric Acid; Continuous Renal Replacement Therapy; Humans; Liver; Liver Di | 2020 |
Regional citrate anticoagulation versus no-anticoagulation for continuous venovenous hemofiltration in patients with liver failure and increased bleeding risk: A retrospective case-control study.
Topics: Adult; Aged; Anticoagulants; Case-Control Studies; Citric Acid; Cohort Studies; Continuous Renal Rep | 2020 |
[Research progress of the application of regional citrate anticoagulation in artificial liver to treat liver failure].
Topics: Acute Kidney Injury; Anticoagulants; Citrates; Citric Acid; Heparin; Humans; Liver Failure; Liver, A | 2020 |
A novel predictive score for citrate accumulation among patients receiving artificial liver support system therapy with regional citrate anticoagulation.
Topics: Anticoagulants; Chlorides; Citric Acid; Creatinine; Female; Humans; International Normalized Ratio; | 2020 |
Impact of anion exchange adsorbents on regional citrate anticoagulation.
Topics: Adsorption; Anion Exchange Resins; Anticoagulants; Bilirubin; Calcium; Citric Acid; Heparin; Humans; | 2021 |
The Safety and Efficacy of Regional Citrate Anticoagulation in Albumin-Assisted Liver Dialysis for Extracorporeal Liver Support in Pediatric Patients.
Topics: Anticoagulants; Child; Child, Preschool; Citric Acid; Female; Hemofiltration; Humans; Infant; Intens | 2019 |
Regional citrate anticoagulation for continuous renal replacement therapy in the perioperative care of liver transplant recipients: a single center experience.
Topics: Acid-Base Equilibrium; Acute Kidney Injury; Anticoagulants; Citric Acid; Cohort Studies; Female; Gra | 2015 |
Safety and efficacy of regional citrate anticoagulation in continuous venovenous hemodialysis in the presence of liver failure: the Liver Citrate Anticoagulation Threshold (L-CAT) observational study.
Topics: Acid-Base Equilibrium; Acidosis; Aged; Alkalosis; Anticoagulants; Citric Acid; Female; Humans; Hypoc | 2015 |
Metabolic and coagulation effects of citrate: down to the last detail!
Topics: Anticoagulants; Citric Acid; Female; Humans; Liver Failure; Male; Renal Dialysis | 2015 |
Continuous venovenous hemodialysis with regional citrate anticoagulation in patients with liver failure: a prospective observational study.
Topics: Acid-Base Equilibrium; Adolescent; Adult; Aged; Anticoagulants; Calcium; Citric Acid; Electrolytes; | 2012 |
Regional citrate anticoagulation in patients with liver failure--time for a rethink?
Topics: Anticoagulants; Citric Acid; Female; Humans; Liver Failure; Male; Renal Dialysis | 2012 |
The series-parallel circuit in the treatment of fulminant hepatitis.
Topics: Adult; Aged; Bilirubin; Citric Acid; Cytokines; Female; Hemodiafiltration; Humans; Liver Failure; Ma | 2004 |
Falsely low calcium measurements after high volume plasma exchange in a patient with liver failure.
Topics: Acidosis, Lactic; Anticoagulants; Antiviral Agents; Arabinofuranosyluracil; Calcium; Citrates; Citri | 1994 |
Increased total to ionized calcium ratio during continuous venovenous hemodialysis with regional citrate anticoagulation.
Topics: Adult; Aged; Aged, 80 and over; Anticoagulants; Calcium; Case-Control Studies; Citric Acid; Female; | 2001 |
1H NMR analysis for metabolites in serum and urine from rats administrated chronically with La(NO3)3.
Topics: Amino Acids; Animals; Citric Acid; Ethylamines; Ketone Bodies; Lactic Acid; Lanthanum; Liver Failure | 2002 |