citric acid, anhydrous has been researched along with Kidney Diseases in 35 studies
Citric Acid: A key intermediate in metabolism. It is an acid compound found in citrus fruits. The salts of citric acid (citrates) can be used as anticoagulants due to their calcium chelating ability.
citric acid : A tricarboxylic acid that is propane-1,2,3-tricarboxylic acid bearing a hydroxy substituent at position 2. It is an important metabolite in the pathway of all aerobic organisms.
Kidney Diseases: Pathological processes of the KIDNEY or its component tissues.
| Excerpt | Relevance | Reference |
|---|---|---|
| " In our study, calcium and uric acid abnormalities were the most common, and vesicoureteral reflux seemed to be the most common urological abnormality which led to urinary stasis and calculus formation." | 3.76 | Metabolic factors associated with urinary calculi in children. ( Alamdaran, SA; Naseri, M; Varasteh, AR, 2010) |
| " She had developed constipation that had led to ileus and had received 34 g of magnesium citrate (Magcolol P) orally the day before." | 3.73 | Hypermagnesemia induced by massive cathartic ingestion in an elderly woman without pre-existing renal dysfunction. ( Hara, A; Ikeda, T; Kontani, M; Ohta, S, 2005) |
| "Since hyperphosphatemia is an established risk factor for not only secondary hyperparathyroidism, but also cardiovascular mortality in these patients, the adequate control of serum phosphorus is necessary." | 2.45 | [Novel phosphate binders under development]. ( Akizawa, T; Mizobuchi, M; Sanada, D, 2009) |
| " No adverse clinical effect was observed." | 1.38 | Safe use of citric acid-based dialysate and heparin removal in postdilution online hemodiafiltration. ( Aniort, J; Créput, C; Petitclerc, T, 2012) |
| " Next, we carried out a 7-day simultaneous treatment study by two daily treatments, that is, FYX-051 (6 mg/kg) and citrate (2,000 mg/kg), followed by citrate-alone treatment, under the conditions of selected dosing intervals, the second dose of citrate, and dosing volume." | 1.37 | Establishment of simultaneous treatment model with citrate for preventing nephropathy induced by FYX-051, a xanthine oxidoreductase inhibitor, in rats. ( Ashizawa, N; Matsumoto, K; Moto, M; Nagata, O; Shimo, T; Taniguchi, T, 2011) |
| "The prevalence of hyperoxaluria (47% vs 10." | 1.36 | Hypocitraturia and hyperoxaluria after Roux-en-Y gastric bypass surgery. ( Guth, ES; Livingston, EH; Maalouf, NM; Sakhaee, K; Tondapu, P, 2010) |
| " Since both BSN and citrate are used clinically as pharmaceuticals, the combination regimen of BSN and citrate may be readily applicable as a countermeasure against the adverse side effects of CDDP without affecting its antitumor activity." | 1.32 | Citrate enhances the protective effect of orally administered bismuth subnitrate against the nephrotoxicity of cis-diamminedichloroplatinum. ( Himeno, S; Imura, N; Kondo, Y; Naganuma, A; Nishimura, T; Satoh, M, 2004) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 9 (25.71) | 18.7374 |
| 1990's | 5 (14.29) | 18.2507 |
| 2000's | 6 (17.14) | 29.6817 |
| 2010's | 13 (37.14) | 24.3611 |
| 2020's | 2 (5.71) | 2.80 |
| Authors | Studies |
|---|---|
| Thanapongsatorn, P | 1 |
| Chaijamorn, W | 1 |
| Sirivongrangson, P | 1 |
| Tachaboon, S | 1 |
| Peerapornratana, S | 1 |
| Lumlertgul, N | 1 |
| Lucksiri, A | 1 |
| Srisawat, N | 1 |
| Klingele, M | 1 |
| Stadler, T | 1 |
| Fliser, D | 1 |
| Speer, T | 1 |
| Groesdonk, HV | 1 |
| Raddatz, A | 1 |
| Mahmood, D | 2 |
| Stegmayr, BG | 2 |
| Francey, T | 1 |
| Schweighauser, A | 1 |
| Saito, D | 1 |
| Fujimaru, T | 1 |
| Inoue, Y | 1 |
| Hirayama, T | 1 |
| Ezaki, I | 1 |
| Kin, H | 1 |
| Shuo, T | 1 |
| Nakayama, M | 1 |
| Komatsu, Y | 1 |
| Hunt, EA | 1 |
| Jain, NG | 1 |
| Somers, MJ | 2 |
| Zou, ZJ | 1 |
| Xie, YY | 1 |
| Gong, MJ | 1 |
| Han, B | 1 |
| Wang, SM | 1 |
| Liang, SW | 1 |
| Al-Ani, B | 1 |
| Fitzpatrick, M | 1 |
| Al-Nuaimi, H | 1 |
| Coughlan, AM | 1 |
| Hickey, FB | 1 |
| Pusey, CD | 1 |
| Savage, C | 1 |
| Benton, CM | 1 |
| O'Brien, EC | 1 |
| O'Toole, D | 1 |
| Mok, KH | 1 |
| Young, SP | 1 |
| Little, MA | 1 |
| Mizobuchi, M | 1 |
| Sanada, D | 1 |
| Akizawa, T | 1 |
| Naseri, M | 1 |
| Varasteh, AR | 1 |
| Alamdaran, SA | 1 |
| Maalouf, NM | 1 |
| Tondapu, P | 1 |
| Guth, ES | 1 |
| Livingston, EH | 1 |
| Sakhaee, K | 1 |
| Zhu, C | 1 |
| Ye, Z | 1 |
| Chen, Z | 1 |
| Xia, D | 1 |
| Hu, J | 1 |
| Ashizawa, N | 2 |
| Shimo, T | 2 |
| Matsumoto, K | 2 |
| Taniguchi, T | 1 |
| Moto, M | 1 |
| Nagata, O | 2 |
| Jonsson, P | 1 |
| Guo, C | 1 |
| Dugas, T | 1 |
| Scates, C | 1 |
| Garcia-Villarreal, M | 1 |
| Ticich, T | 1 |
| McMartin, KE | 1 |
| Aniort, J | 1 |
| Petitclerc, T | 1 |
| Créput, C | 1 |
| LAWRIE, TD | 1 |
| HARRISON, HE | 1 |
| HARRISON, HC | 1 |
| NORDMANN, R | 1 |
| MARTY, A | 1 |
| NORDMANN, J | 1 |
| DEDMON, RE | 1 |
| WRONG, O | 1 |
| DREWES, VM | 1 |
| TOROK, J | 1 |
| TURAY, P | 1 |
| KOVACS, Z | 1 |
| BRODWALL, EK | 1 |
| LAAKE, H | 1 |
| NORDIN, BE | 1 |
| SMITH, DA | 1 |
| Kondo, Y | 1 |
| Himeno, S | 1 |
| Satoh, M | 1 |
| Naganuma, A | 1 |
| Nishimura, T | 1 |
| Imura, N | 1 |
| Brophy, PD | 1 |
| Baum, MA | 1 |
| Symons, JM | 1 |
| McAfee, N | 1 |
| Fortenberry, JD | 1 |
| Rogers, K | 1 |
| Barnett, J | 1 |
| Blowey, D | 1 |
| Baker, C | 1 |
| Bunchman, TE | 1 |
| Goldstein, SL | 1 |
| Nakazawa, T | 1 |
| Kontani, M | 1 |
| Hara, A | 1 |
| Ohta, S | 1 |
| Ikeda, T | 1 |
| Buchman, AL | 1 |
| Moukarzel, AA | 1 |
| Ament, ME | 1 |
| Osther, PJ | 1 |
| Bollerslev, J | 1 |
| Hansen, AB | 1 |
| Engel, K | 1 |
| Kildeberg, P | 1 |
| Aasarød, K | 1 |
| Haga, HJ | 1 |
| Berg, KJ | 1 |
| Hammerstrøm, J | 1 |
| Jørstad, S | 1 |
| Rodman, JS | 1 |
| Berty, RM | 1 |
| Adler, S | 1 |
| Jaikishen, P | 1 |
| Oster, ZH | 1 |
| Atkins, HL | 1 |
| Hiraishi, K | 1 |
| Nakamura, S | 1 |
| Kurokawa, K | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Apple Cider Vinegar for the Prevention of Urinary Lithiasis (APUL)[NCT04073719] | 50 participants (Anticipated) | Interventional | 2019-09-01 | Not yet recruiting | |||
| Comparison of Citrate Dialysate in Predilution and Postdilution Online Hemodiafiltration : Effect on Clot Formation and Adequacy of Dialysis in Hemodialysis Patients[NCT05280106] | 9 participants (Actual) | Interventional | 2022-02-01 | Completed | |||
| Simplified Regional Citrate Anticoagulation Protocols for CVVH, CVVHDF and SLED Focused on the Prevention of RRT-related Hypophosphatemia and Optimization of Acid-base Balance: a Pilot Study[NCT03976440] | 30 participants (Anticipated) | Observational | 2019-06-01 | Active, not recruiting | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
3 reviews available for citric acid, anhydrous and Kidney Diseases
| Article | Year |
|---|---|
Apheresis therapy in children: an overview of key technical aspects and a review of experience in pediatric renal disease.
Topics: Adolescent; Anticoagulants; Anxiety; Blood Component Removal; Blood Volume; Catheterization, Central | 2013 |
[Novel phosphate binders under development].
Topics: Bile Acids and Salts; Chronic Disease; Citric Acid; Clinical Trials as Topic; Drug Design; Ferrous C | 2009 |
[Metabolic disturbances in renal tubular acidosis; calcium and phosphorus metabolism (kidney calculi and kidney calcinosis)].
Topics: Acidosis, Renal Tubular; Calcinosis; Calcium; Citrates; Citric Acid; Humans; Hydrogen-Ion Concentrat | 1985 |
2 trials available for citric acid, anhydrous and Kidney Diseases
| Article | Year |
|---|---|
Haemodialysis with Tinzaparin Versus Dialysate Citrate as Anticoagulation.
Topics: Aged; Aged, 80 and over; Anticoagulants; C-Reactive Protein; Cholesterol, LDL; Citric Acid; Dialysis | 2018 |
A significant proportion of patients treated with citrate containing dialysate need additional anticoagulation.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anticoagulants; Blood Coagulation; Citric Acid; Cross-Ov | 2013 |
30 other studies available for citric acid, anhydrous and Kidney Diseases
| Article | Year |
|---|---|
Citrate pharmacokinetics in critically ill liver failure patients receiving CRRT.
Topics: Acute-On-Chronic Liver Failure; Adult; Aged; Aged, 80 and over; Anticoagulants; Citric Acid; Continu | 2022 |
Long-term continuous renal replacement therapy and anticoagulation with citrate in critically ill patients with severe liver dysfunction.
Topics: Academic Medical Centers; Aged; Aged, 80 and over; Anticoagulants; Blood Coagulation; Citric Acid; C | 2017 |
Membrane-based therapeutic plasma exchange in dogs: Prescription, anticoagulation, and metabolic response.
Topics: Animals; Anticoagulants; Blood Proteins; Citric Acid; Dog Diseases; Dogs; Female; Heparin; Kidney Di | 2019 |
Serial measurement of electrolyte and citrate concentrations in blood-primed continuous hemodialysis circuits during closed-circuit dialysis.
Topics: Calcium; Chlorides; Citric Acid; Critical Illness; Dialysis Solutions; Electrolytes; Erythrocyte Tra | 2020 |
[Urine metabonomic study of intervention effects of Morinda officinalis how. on 'kidney-yang deficiency syndrome'].
Topics: Alanine; Animals; Betaine; Biomarkers; Citric Acid; Drugs, Chinese Herbal; Hydrocortisone; Ketogluta | 2013 |
Changes in urinary metabolomic profile during relapsing renal vasculitis.
Topics: Animals; Anti-Neutrophil Cytoplasmic Antibody-Associated Vasculitis; Citric Acid; Disease Models, An | 2016 |
Metabolic factors associated with urinary calculi in children.
Topics: Adolescent; Calcium; Child; Child, Preschool; Citric Acid; Cystinuria; Female; Humans; Hypercalciuri | 2010 |
Hypocitraturia and hyperoxaluria after Roux-en-Y gastric bypass surgery.
Topics: Citric Acid; Cross-Sectional Studies; Female; Gastric Bypass; Humans; Hyperoxaluria; Kidney Diseases | 2010 |
Association between vitamin D receptor gene polymorphisms and idiopathic hypocitraturia in the Chinese population.
Topics: Asian People; Biomarkers; Case-Control Studies; China; Citric Acid; Gene Frequency; Genetic Predispo | 2010 |
Establishment of simultaneous treatment model with citrate for preventing nephropathy induced by FYX-051, a xanthine oxidoreductase inhibitor, in rats.
Topics: Animals; Chelating Agents; Citric Acid; Disease Models, Animal; Enzyme Inhibitors; Kidney Diseases; | 2011 |
Aluminum citrate blocks toxicity of calcium oxalate crystals by preventing binding with cell membrane phospholipids.
Topics: Calcium Oxalate; Cells, Cultured; Citric Acid; Humans; Kidney Diseases; Kidney Tubules, Proximal; Li | 2013 |
Safe use of citric acid-based dialysate and heparin removal in postdilution online hemodiafiltration.
Topics: Aged; Blood Chemical Analysis; Blood Coagulation; Citric Acid; Female; Hemodiafiltration; Hemodialys | 2012 |
Nephrocalcinosis: report of a case showing an apparent response to citrate therapy.
Topics: Calcinosis; Citrates; Citric Acid; Humans; Kidney Diseases; Nephrocalcinosis | 1954 |
Inhibition of urine citrate excretion and the production of renal calcinosis in the rat by acetazoleamide (diamox) administration.
Topics: Acetazolamide; Animals; Calcinosis; Citrates; Citric Acid; Diuretics; Hydro-Lyases; Kidney Diseases; | 1955 |
[Citrate in blood during renal insufficiency].
Topics: Citrates; Citric Acid; Kidney Diseases; Renal Insufficiency; Ureteral Diseases; Vascular Diseases | 1959 |
The excretion of organic anion in renal tubular acidosis with particular reference to citrate.
Topics: Acidosis, Renal Tubular; Anions; Body Fluids; Citrates; Citric Acid; Humans; Kidney Diseases; Urinar | 1962 |
[Renal tubule acidosis. A case with symptom-producing hypokalemia and normal citrate excretion].
Topics: Acid-Base Equilibrium; Acidosis; Citrates; Citric Acid; Humans; Hypokalemia; Kidney Diseases; Medica | 1962 |
[Clinical aspects of citric acid metabolism].
Topics: Citric Acid; Citric Acid Cycle; Humans; Kidney Diseases | 1963 |
THE RENAL METABOLISM OF CITRIC ACID.
Topics: Blood Chemical Analysis; Catheterization; Citrates; Citric Acid; Humans; Kidney; Kidney Diseases; Ki | 1963 |
CITRIC ACID EXCRETION IN RENAL STONE DISEASE AND IN RENAL TUBULAR ACIDOSIS.
Topics: Acidosis; Acidosis, Renal Tubular; Citrates; Citric Acid; Creatine; Creatinine; Humans; Hyperparathy | 1963 |
Citrate enhances the protective effect of orally administered bismuth subnitrate against the nephrotoxicity of cis-diamminedichloroplatinum.
Topics: Administration, Oral; Animals; Bismuth; Cisplatin; Citric Acid; Drug Synergism; Fibrosarcoma; Kidney | 2004 |
Multi-centre evaluation of anticoagulation in patients receiving continuous renal replacement therapy (CRRT).
Topics: Adolescent; Adult; Anticoagulants; Child; Child, Preschool; Citric Acid; Follow-Up Studies; Graft Oc | 2005 |
Simultaneous treatment with citrate prevents nephropathy induced by FYX-051, a xanthine oxidoreductase inhibitor, in rats.
Topics: Animals; Citric Acid; Crystallization; Dogs; Dose-Response Relationship, Drug; Enzyme Inhibitors; Fe | 2005 |
Hypermagnesemia induced by massive cathartic ingestion in an elderly woman without pre-existing renal dysfunction.
Topics: Administration, Oral; Aged; Blood Pressure; Cathartics; Citric Acid; Constipation; Electrocardiograp | 2005 |
Excessive urinary oxalate excretion occurs in long-term TPN patients both with and without ileostomies.
Topics: Absorption; Adult; Aged; Citrates; Citric Acid; Female; Glomerular Filtration Rate; Humans; Hyperoxa | 1995 |
Pathophysiology of incomplete renal tubular acidosis in recurrent renal stone formers: evidence of disturbed calcium, bone and citrate metabolism.
Topics: Acid-Base Equilibrium; Acidosis; Adult; Aged; Bone and Bones; Calcium; Citrates; Citric Acid; Female | 1993 |
Renal involvement in primary Sjögren's syndrome.
Topics: Acetylglucosaminidase; Acidosis, Renal Tubular; Adult; Aged; Alkaline Phosphatase; beta 2-Microglobu | 2000 |
Prophylaxis of uric acid stones with alternate day doses of alkaline potassium salts.
Topics: Adult; Aged; Bicarbonates; Citrates; Citric Acid; Colic; Follow-Up Studies; Humans; Hydrogen-Ion Con | 1991 |
In vivo and in vitro rat model for cyclosporine-induced proximal tubular toxicity.
Topics: Acetylglucosaminidase; Ammonia; Animals; Citrates; Citric Acid; Cyclosporins; Disease Models, Animal | 1991 |
The scintigraphic pattern of renal angiomyolipoma.
Topics: Abscess; Adult; Citrates; Citric Acid; Diagnosis, Differential; Gallium Radioisotopes; Hemangioma; H | 1990 |