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citric acid, anhydrous and Diseases, Metabolic

citric acid, anhydrous has been researched along with Diseases, Metabolic in 21 studies

Citric Acid: A key intermediate in metabolism. It is an acid compound found in citrus fruits. The salts of citric acid (citrates) can be used as anticoagulants due to their calcium chelating ability.
citric acid : A tricarboxylic acid that is propane-1,2,3-tricarboxylic acid bearing a hydroxy substituent at position 2. It is an important metabolite in the pathway of all aerobic organisms.

Research Excerpts

ExcerptRelevanceReference
" TPM dosage correlated inversely with urinary citrate excretion (Pearson correlation coefficient = -0."5.37Patients with and without prior urolithiasis have hypocitraturia and incident kidney stones while on topiramate. ( Kaplon, DM; Nakada, SY; Penniston, KL, 2011)
"This study revealed a metabolic tendency to hypercalciuria in calcium oxalate stone patients, predominantly in those with recurrent calcium oxalate urolithiasis."3.83Metabolic assessment of recurrent and first renal calcium oxalate stone formers. ( Çakıroğlu, B; Eyyupoğlu, E; Hazar, AI; Nuhoğlu, B; Uyanik, BS, 2016)
" In our study, calcium and uric acid abnormalities were the most common, and vesicoureteral reflux seemed to be the most common urological abnormality which led to urinary stasis and calculus formation."3.76Metabolic factors associated with urinary calculi in children. ( Alamdaran, SA; Naseri, M; Varasteh, AR, 2010)
"Patients with urolithiasis have a lower bone mineral density (BMD) than those without stones, suggesting a potential correlation between calcium stone formation and bone resorption disorders, including osteopenia and osteoporosis."1.56Low bone mineral density is a potential risk factor for symptom onset and related with hypocitraturia in urolithiasis patients: a single-center retrospective cohort study. ( Ando, R; Hamamoto, S; Kato, T; Okada, A; Sugino, T; Taguchi, K; Tanaka, Y; Tozawa, K; Unno, R; Yasui, T, 2020)
" TPM dosage correlated inversely with urinary citrate excretion (Pearson correlation coefficient = -0."1.37Patients with and without prior urolithiasis have hypocitraturia and incident kidney stones while on topiramate. ( Kaplon, DM; Nakada, SY; Penniston, KL, 2011)
"Hypercalciuria was detected in 9/47, hyperoxaluria in 5/39, hypocitraturia in 4/31, and cystinuria in 2/50 infants."1.36Urolithiasis in the first year of life. ( Akbas, H; Akman, S; Alimoglu, E; Baysal, YE; Güven, AG; Kabaalioglu, A; Koyun, M, 2010)
"Urolithiasis is one of the commonest problems in pediatric nephrology."1.36Clinical manifestations and etiology of renal stones in children less than 14 years age. ( Heidari, A; Sepahi, MA; Shajari, A, 2010)

Research

Studies (21)

TimeframeStudies, this research(%)All Research%
pre-19903 (14.29)18.7374
1990's2 (9.52)18.2507
2000's4 (19.05)29.6817
2010's8 (38.10)24.3611
2020's4 (19.05)2.80

Authors

AuthorsStudies
Akhtar, MJ2
Khan, SA2
Kumar, B2
Chawla, P2
Bhatia, R2
Singh, K2
Taguchi, K1
Hamamoto, S1
Okada, A1
Tanaka, Y1
Sugino, T1
Unno, R1
Kato, T1
Ando, R1
Tozawa, K1
Yasui, T1
Huynh, LM1
Dianatnejad, S1
Tofani, S1
Carrillo Ceja, R1
Liang, K1
Tapiero, S1
Jiang, P1
Youssef, RF1
Mosaoa, R1
Kasprzyk-Pawelec, A1
Fernandez, HR1
Avantaggiati, ML1
Willmes, DM1
Kurzbach, A1
Henke, C1
Schumann, T1
Zahn, G1
Heifetz, A1
Jordan, J1
Helfand, SL1
Birkenfeld, AL1
Khadzhynov, D1
Schelter, C1
Lieker, I1
Mika, A1
Staeck, O1
Neumayer, HH1
Peters, H1
Slowinski, T1
Çakıroğlu, B1
Eyyupoğlu, E1
Hazar, AI1
Uyanik, BS1
Nuhoğlu, B1
Kustov, AV1
Moryganov, MA1
Strel'nikov, AI1
Zhuravleva, NI1
Airapetyan, AO1
Stoller, ML1
Chi, T1
Eisner, BH1
Shami, G1
Gentle, DL1
Alpay, H1
Ozen, A1
Gokce, I1
Biyikli, N1
Güven, AG1
Koyun, M1
Baysal, YE1
Akman, S1
Alimoglu, E1
Akbas, H1
Kabaalioglu, A1
Sepahi, MA1
Heidari, A1
Shajari, A1
Naseri, M1
Varasteh, AR1
Alamdaran, SA1
Kaplon, DM1
Penniston, KL1
Nakada, SY1
NORDIO, S1
DE PRA, M1
KOMARKOVA, A1
VITKOVA, E1
PACOVSKY, V1
VOSTAL, J1
BLEHA, O1
Kang, DE1
Sur, RL1
Haleblian, GE1
Fitzsimons, NJ1
Borawski, KM1
Preminger, GM1
Scott, WA1
Campoy Martínez, P1
Reina Ruiz, C1
Salazar Murillo, R1
Quintero Rodríguez, R1
Espinosa Olmedo, FJ1
García Pérez, M1
Schelling, JR1
Laminski, NA1
Meyers, AM1
Sonnekus, MI1
Smyth, AE1

Clinical Trials (2)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Evaluation of Filters Useful Life, Metabolic Control, Electrolyte Profile and Acid-base Balance During Regional Anticoagulation With 4% Trisodium Citrate in Patients Undergoing CVVHDF: Effects of Increased Blood Flow[NCT05796661]27 participants (Anticipated)Interventional2023-01-09Recruiting
Apple Cider Vinegar for the Prevention of Urinary Lithiasis (APUL)[NCT04073719]50 participants (Anticipated)Interventional2019-09-01Not yet recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

4 reviews available for citric acid, anhydrous and Diseases, Metabolic

ArticleYear
Role of sodium dependent SLC13 transporter inhibitors in various metabolic disorders.
    Molecular and cellular biochemistry, 2023, Volume: 478, Issue:8

    Topics: Animals; Citrates; Citric Acid; Fatty Acids; Humans; Membrane Transport Proteins; Metabolic Diseases

2023
Role of sodium dependent SLC13 transporter inhibitors in various metabolic disorders.
    Molecular and cellular biochemistry, 2023, Volume: 478, Issue:8

    Topics: Animals; Citrates; Citric Acid; Fatty Acids; Humans; Membrane Transport Proteins; Metabolic Diseases

2023
Role of sodium dependent SLC13 transporter inhibitors in various metabolic disorders.
    Molecular and cellular biochemistry, 2023, Volume: 478, Issue:8

    Topics: Animals; Citrates; Citric Acid; Fatty Acids; Humans; Membrane Transport Proteins; Metabolic Diseases

2023
Role of sodium dependent SLC13 transporter inhibitors in various metabolic disorders.
    Molecular and cellular biochemistry, 2023, Volume: 478, Issue:8

    Topics: Animals; Citrates; Citric Acid; Fatty Acids; Humans; Membrane Transport Proteins; Metabolic Diseases

2023
Metabolic diagnoses of recurrent stone formers: temporal, geographic and gender differences.
    Scandinavian journal of urology, 2020, Volume: 54, Issue:6

    Topics: Citric Acid; Female; Global Health; Humans; Hypercalciuria; Hyperoxaluria; Kidney Calculi; Male; Met

2020
The Mitochondrial Citrate Carrier SLC25A1/CIC and the Fundamental Role of Citrate in Cancer, Inflammation and Beyond.
    Biomolecules, 2021, 01-22, Volume: 11, Issue:2

    Topics: Allosteric Site; Animals; Chromosomes, Human, Pair 22; Citrates; Citric Acid; Cytosol; Diabetes Mell

2021
The longevity gene INDY (I'm Not Dead Yet) in metabolic control: Potential as pharmacological target.
    Pharmacology & therapeutics, 2018, Volume: 185

    Topics: Animals; Citric Acid; Dicarboxylic Acid Transporters; Humans; Longevity; Metabolic Diseases; Neurons

2018

Trials

1 trial available for citric acid, anhydrous and Diseases, Metabolic

ArticleYear
Prevalence of hypocitraturia and hypopyrophosphaturia in recurrent calcium stone formers: as isolated defects or associated with other metabolic abnormalities.
    Nephron, 1990, Volume: 56, Issue:4

    Topics: Adolescent; Adult; Aged; Calcium; Citrates; Citric Acid; Diphosphates; Female; Humans; Kidney Calcul

1990

Other Studies

16 other studies available for citric acid, anhydrous and Diseases, Metabolic

ArticleYear
Low bone mineral density is a potential risk factor for symptom onset and related with hypocitraturia in urolithiasis patients: a single-center retrospective cohort study.
    BMC urology, 2020, Oct-29, Volume: 20, Issue:1

    Topics: Adult; Aged; Bone Diseases, Metabolic; Citric Acid; Cohort Studies; Correlation of Data; Female; Hum

2020
Incidence and outcome of metabolic disarrangements consistent with citrate accumulation in critically ill patients undergoing continuous venovenous hemodialysis with regional citrate anticoagulation.
    Journal of critical care, 2014, Volume: 29, Issue:2

    Topics: Acute Kidney Injury; Aged; Anticoagulants; Calcium; Citrates; Citric Acid; Critical Illness; Female;

2014
Metabolic assessment of recurrent and first renal calcium oxalate stone formers.
    Archivio italiano di urologia, andrologia : organo ufficiale [di] Societa italiana di ecografia urologica e nefrologica, 2016, Jul-04, Volume: 88, Issue:2

    Topics: Adult; Calcium; Calcium Oxalate; Citric Acid; Female; Follow-Up Studies; Humans; Hypercalciuria; Kid

2016
[Quantitative mineralogical analyzes of kidney stones and diagnosing metabolic disorders in female patients with calcium oxalate urolithiasis].
    Urologiia (Moscow, Russia : 1999), 2016, Issue:1

    Topics: Adult; Age Factors; Aged; Calcium Oxalate; Citric Acid; Durapatite; Female; Humans; Kidney Calculi;

2016
Changes in urinary stone risk factors in hypocitraturic calcium oxalate stone formers treated with dietary sodium supplementation.
    The Journal of urology, 2009, Volume: 181, Issue:3

    Topics: Adult; Aged; Calcium Oxalate; Citric Acid; Dietary Supplements; Female; Humans; Kidney Calculi; Male

2009
Clinical and metabolic features of urolithiasis and microlithiasis in children.
    Pediatric nephrology (Berlin, Germany), 2009, Volume: 24, Issue:11

    Topics: Calcium; Child; Child, Preschool; Citric Acid; Cystinuria; Female; Humans; Hypercalciuria; Hyperoxal

2009
Urolithiasis in the first year of life.
    Pediatric nephrology (Berlin, Germany), 2010, Volume: 25, Issue:1

    Topics: Blood Chemical Analysis; Child, Preschool; Citric Acid; Cystinuria; Female; Humans; Hypercalciuria;

2010
Clinical manifestations and etiology of renal stones in children less than 14 years age.
    Saudi journal of kidney diseases and transplantation : an official publication of the Saudi Center for Organ Transplantation, Saudi Arabia, 2010, Volume: 21, Issue:1

    Topics: Adolescent; Child; Child, Preschool; Citric Acid; Cystinuria; Dysuria; Female; Fever; Genetic Predis

2010
Metabolic factors associated with urinary calculi in children.
    Iranian journal of kidney diseases, 2010, Volume: 4, Issue:1

    Topics: Adolescent; Calcium; Child; Child, Preschool; Citric Acid; Cystinuria; Female; Humans; Hypercalciuri

2010
Patients with and without prior urolithiasis have hypocitraturia and incident kidney stones while on topiramate.
    Urology, 2011, Volume: 77, Issue:2

    Topics: Anticonvulsants; Citric Acid; Female; Fructose; Humans; Kidney Calculi; Male; Metabolic Diseases; Re

2011
[Renal clearance of citric acid in some diseases of calciophosphoric metabolism. A new form of rickets (with "citric renal diabetes")].
    Minerva pediatrica, 1961, Jan-28, Volume: 13

    Topics: Citrates; Citric Acid; Diabetes Mellitus; Humans; Kidney Function Tests; Metabolic Diseases; Rickets

1961
[Citric acid and metabolic diseases of the bone. I. Preliminary communication. Certain new finding on metabolic relation of citric acid to bones].
    Casopis lekaru ceskych, 1959, Aug-14, Volume: 98

    Topics: Bone and Bones; Citrates; Citric Acid; Metabolic Diseases

1959
Long-term lemonade based dietary manipulation in patients with hypocitraturic nephrolithiasis.
    The Journal of urology, 2007, Volume: 177, Issue:4

    Topics: Adult; Aged; Beverages; Citric Acid; Citrus; Female; Humans; Male; Metabolic Diseases; Middle Aged;

2007
Asymptomatic hyperuricaemia and its early treatment.
    The Journal of international medical research, 1980, Volume: 8, Issue:1

    Topics: Bicarbonates; Citrates; Citric Acid; Drug Combinations; Female; Humans; Male; Metabolic Diseases; So

1980
[A metabolic study of urolithiasis. Specificity, sensitivity, efficacy and reproducibility].
    Annales d'urologie, 1995, Volume: 29, Issue:6-7

    Topics: Absorption; Adolescent; Adult; Aged; Calcium; Citrates; Citric Acid; Clinical Protocols; Creatinine;

1995
Fatal hypermagnesemia.
    Clinical nephrology, 2000, Volume: 53, Issue:1

    Topics: Acute Kidney Injury; Aged; Aged, 80 and over; Cathartics; Citric Acid; Fatal Outcome; Female; Humans

2000