Page last updated: 2024-10-17

citric acid, anhydrous and Delayed Graft Function

citric acid, anhydrous has been researched along with Delayed Graft Function in 3 studies

Citric Acid: A key intermediate in metabolism. It is an acid compound found in citrus fruits. The salts of citric acid (citrates) can be used as anticoagulants due to their calcium chelating ability.
citric acid : A tricarboxylic acid that is propane-1,2,3-tricarboxylic acid bearing a hydroxy substituent at position 2. It is an important metabolite in the pathway of all aerobic organisms.

Delayed Graft Function: General dysfunction of an organ occurring immediately following its transplantation. The term most frequently refers to renal dysfunction following KIDNEY TRANSPLANTATION.

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's3 (100.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Wang, Z1
Yang, H1
Zhao, C1
Wei, J1
Wang, J1
Han, Z1
Tao, J1
Xu, Z1
Ju, X1
Tan, R1
Gu, M1
Sui, M1
Zhang, L1
Yang, J1
Zeng, L1
Zhao, W1
Zhu, Y1
Robert, R1
Guilhot, J1
Pinsard, M1
Longeard, PL1
Jacob, JP1
Gissot, V1
Hauet, T1
Seguin, F1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Angiotensin II in the Perioperative Management of Hypotension in Kidney Transplant[NCT04529005]Phase 420 participants (Actual)Interventional2020-08-13Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trial Outcomes

Duration of ATII Vasopressor Usage in the Intraoperative Setting

Duration of vasopressor usage while in the operating room measured in hours of usage presented as median and IQR. (NCT04529005)
Timeframe: Duration of usage during the transplant surgery - presented in hours

Interventionhours (Median)
Angiotensin II (Giapreza)1

Number (and Percentage) of Patients With Arrhythmias

The presence of arrhythmia was confirmed via EKG, flowsheet, or note documentation from the electronic medical record. (NCT04529005)
Timeframe: From date and time of study drug initiation during or after transplant operation until study drug is discontinued up to a maximum of 30 days.

InterventionParticipants (Count of Participants)
Angiotensin II (Giapreza)1

Number (and Percentage) of Patients With Delayed Graft Function

The presence of Delayed Graft Function was captured for each patient and defined by the need for renal replacement therapy up to 7 days post-operative. (NCT04529005)
Timeframe: From post-op to 7 days post-op

InterventionParticipants (Count of Participants)
Angiotensin II (Giapreza)2

Number (and Percentage) of Patients With Fungal Infections

The presence of post-operative fungal infections were captured prior to discharge as documented by the clinical care team in the electronic medical record. (NCT04529005)
Timeframe: From date and time of study drug initiation during or after transplant operation until study drug is discontinued up to a maximum of 30 days.

InterventionParticipants (Count of Participants)
Angiotensin II (Giapreza)0

Number (and Percentage) of Patients With Hyperglycemia

The presence of hyperglycemia was captured for each patient and was determined by those patients requiring the use of an insulin infusion after their transplant surgery. (NCT04529005)
Timeframe: From date and time of study drug initiation during or after transplant operation until study drug is discontinued up to a maximum of 30 days.

InterventionParticipants (Count of Participants)
Angiotensin II (Giapreza)1

Number (and Percentage) of Patients With Peripheral/Visceral Ischemia

The presence of digital or other peripheral/visceral ischemia was captured from reviewing chart documentation for each patient. (NCT04529005)
Timeframe: From date and time of study drug initiation during or after transplant operation until study drug is discontinued up to a maximum of 30 days.

InterventionParticipants (Count of Participants)
Angiotensin II (Giapreza)0

Number (and Percentage) of Patients With Thrombosis

Incidence of venous or arterial thrombosis occurring during the hospitalization for kidney transplant (captured by ultrasound or other diagnostic imaging) (NCT04529005)
Timeframe: From date and time of study drug initiation during or after transplant operation until study drug is discontinued up to a maximum of 30 days.

InterventionParticipants (Count of Participants)
Angiotensin II (Giapreza)0

Trials

1 trial available for citric acid, anhydrous and Delayed Graft Function

ArticleYear
A new HC-A II solution for kidney preservation: A multi-center randomized controlled trial in China.
    Annals of transplantation, 2014, Nov-27, Volume: 19

    Topics: Adenine; Adolescent; Adult; China; Citric Acid; Cold Ischemia; Delayed Graft Function; Double-Blind

2014

Other Studies

2 other studies available for citric acid, anhydrous and Delayed Graft Function

ArticleYear
Proton Nuclear Magnetic Resonance (¹H-NMR)-Based Metabolomic Evaluation of Human Renal Allografts from Donations After Circulatory Death.
    Medical science monitor : international medical journal of experimental and clinical research, 2017, Nov-17, Volume: 23

    Topics: Adult; Allografts; Betaine; Citric Acid; Delayed Graft Function; Female; Glucose; Humans; Kidney; Ki

2017
A pair analysis of the delayed graft function in kidney recipient: the critical role of the donor.
    Journal of critical care, 2010, Volume: 25, Issue:4

    Topics: Adolescent; Adult; Age Factors; Aged; Biomarkers; Brain Death; Child; Citric Acid; Delayed Graft Fun

2010