citric acid, anhydrous has been researched along with Constipation in 17 studies
Citric Acid: A key intermediate in metabolism. It is an acid compound found in citrus fruits. The salts of citric acid (citrates) can be used as anticoagulants due to their calcium chelating ability.
citric acid : A tricarboxylic acid that is propane-1,2,3-tricarboxylic acid bearing a hydroxy substituent at position 2. It is an important metabolite in the pathway of all aerobic organisms.
Constipation: Infrequent or difficult evacuation of FECES. These symptoms are associated with a variety of causes, including low DIETARY FIBER intake, emotional or nervous disturbances, systemic and structural disorders, drug-induced aggravation, and infections.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Split 2-L PEG-CS plus bisacodyl was not superior to split 4-L PEG for colonoscopy bowel cleansing in patients with chronic constipation; however, it performed better than the standard regimen in terms of colonic mucosa visualization, patient acceptance and compliance." | 9.20 | 2-Litre polyethylene glycol-citrate-simethicone plus bisacodyl versus 4-litre polyethylene glycol as preparation for colonoscopy in chronic constipation. ( Arena, M; Baccarin, A; Bargiggia, S; Fontana, P; Manes, G; Masci, E; Mazzoleni, G; Parente, F; Spinzi, G; Testoni, PA; Vailati, C, 2015) |
| " The aim of the study was to compare the clinical efficacy and tolerability of fibre versus lactulose in outpatients with chronic constipation." | 9.12 | Prospective randomized crossover trial comparing fibre with lactulose in the treatment of idiopathic chronic constipation. ( Ho, KS; Ooi, BS; Quah, HM; Seow-Choen, F; Sng, KK, 2006) |
| "A case study reporting the efficacy of oral vancomycin in a patient with chronic idiopathic constipation prompted this prospective trial of oral vancomycin in eight female patients (aged 21-61 years) with severe constipation resistant to the action of dietary fibre." | 9.08 | The effect of oral vancomycin on chronic idiopathic constipation. ( Celik, AF; Read, NW; Tomlin, J, 1995) |
| "The efficacy, tolerance and acceptability of lactulose (Duphalac) and ispaghula (Fybogel Orange) were assessed in the treatment of chronic constipation in adults." | 9.07 | An open, randomised, parallel group study of lactulose versus ispaghula in the treatment of chronic constipation in adults. ( Atkinson, SN; Chapman, N; Grillage, M; Mahapatra, M; Prescott, P; Rouse, M, 1991) |
| "Split 2-L PEG-CS plus bisacodyl was not superior to split 4-L PEG for colonoscopy bowel cleansing in patients with chronic constipation; however, it performed better than the standard regimen in terms of colonic mucosa visualization, patient acceptance and compliance." | 5.20 | 2-Litre polyethylene glycol-citrate-simethicone plus bisacodyl versus 4-litre polyethylene glycol as preparation for colonoscopy in chronic constipation. ( Arena, M; Baccarin, A; Bargiggia, S; Fontana, P; Manes, G; Masci, E; Mazzoleni, G; Parente, F; Spinzi, G; Testoni, PA; Vailati, C, 2015) |
| " The aim of the study was to compare the clinical efficacy and tolerability of fibre versus lactulose in outpatients with chronic constipation." | 5.12 | Prospective randomized crossover trial comparing fibre with lactulose in the treatment of idiopathic chronic constipation. ( Ho, KS; Ooi, BS; Quah, HM; Seow-Choen, F; Sng, KK, 2006) |
| "A case study reporting the efficacy of oral vancomycin in a patient with chronic idiopathic constipation prompted this prospective trial of oral vancomycin in eight female patients (aged 21-61 years) with severe constipation resistant to the action of dietary fibre." | 5.08 | The effect of oral vancomycin on chronic idiopathic constipation. ( Celik, AF; Read, NW; Tomlin, J, 1995) |
| "The efficacy, tolerance and acceptability of lactulose (Duphalac) and ispaghula (Fybogel Orange) were assessed in the treatment of chronic constipation in adults." | 5.07 | An open, randomised, parallel group study of lactulose versus ispaghula in the treatment of chronic constipation in adults. ( Atkinson, SN; Chapman, N; Grillage, M; Mahapatra, M; Prescott, P; Rouse, M, 1991) |
| " Although Picolax (sodium picosulphate and magnesium citrate) has been widely documented for use in bowel preparation, there is limited literature on its efficacy in the treatment of constipation." | 3.78 | A pilot study on the efficacy of Picolax given as a four-week course for the treatment of refractory constipation. ( Chan, AO, 2012) |
| " She had developed constipation that had led to ileus and had received 34 g of magnesium citrate (Magcolol P) orally the day before." | 3.73 | Hypermagnesemia induced by massive cathartic ingestion in an elderly woman without pre-existing renal dysfunction. ( Hara, A; Ikeda, T; Kontani, M; Ohta, S, 2005) |
| " The second patient was a 67-year-old woman with mild renal insufficiency, who consumed a large amount of Epsom salts containing magnesium sulfate to treat her constipation." | 3.69 | Hypermagnesemia-induced paralytic ileus. ( Golzarian, J; Richards, WO; Scott, HW, 1994) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (5.88) | 18.7374 |
| 1990's | 5 (29.41) | 18.2507 |
| 2000's | 4 (23.53) | 29.6817 |
| 2010's | 5 (29.41) | 24.3611 |
| 2020's | 2 (11.76) | 2.80 |
| Authors | Studies |
|---|---|
| Na, JR | 1 |
| Kim, E | 1 |
| Na, CS | 1 |
| Kim, S | 1 |
| Dixon, AM | 1 |
| Styres, C | 1 |
| Straatmann, C | 1 |
| Bokhari, SR | 1 |
| Siriki, R | 1 |
| Teran, FJ | 1 |
| Batuman, V | 1 |
| Freedman, SB | 1 |
| Thull-Freedman, J | 1 |
| Rumantir, M | 1 |
| Eltorki, M | 1 |
| Schuh, S | 1 |
| Parente, F | 1 |
| Vailati, C | 1 |
| Bargiggia, S | 1 |
| Manes, G | 1 |
| Fontana, P | 1 |
| Masci, E | 1 |
| Arena, M | 1 |
| Spinzi, G | 1 |
| Baccarin, A | 1 |
| Mazzoleni, G | 1 |
| Testoni, PA | 1 |
| Patel, M | 1 |
| Schimpf, MO | 1 |
| O'Sullivan, DM | 1 |
| LaSala, CA | 1 |
| Chan, AO | 1 |
| Garcia, MC | 1 |
| Byrd, RP | 1 |
| Roy, TM | 1 |
| Kontani, M | 1 |
| Hara, A | 1 |
| Ohta, S | 1 |
| Ikeda, T | 1 |
| Quah, HM | 1 |
| Ooi, BS | 1 |
| Seow-Choen, F | 1 |
| Sng, KK | 1 |
| Ho, KS | 1 |
| Eogan, M | 1 |
| Daly, L | 1 |
| Behan, M | 1 |
| O'Connell, PR | 1 |
| O'Herlihy, C | 1 |
| Smith, RG | 1 |
| Rowe, MJ | 1 |
| Smith, AN | 1 |
| Eastwood, MA | 1 |
| Drummond, E | 1 |
| Brydon, WG | 1 |
| Celik, AF | 1 |
| Tomlin, J | 1 |
| Read, NW | 1 |
| Golzarian, J | 1 |
| Scott, HW | 1 |
| Richards, WO | 1 |
| Davies, GJ | 1 |
| Dettmar, PW | 1 |
| Hoare, RC | 1 |
| Dharmarajan, TS | 1 |
| Patel, B | 1 |
| Varshneya, N | 1 |
| Rouse, M | 1 |
| Chapman, N | 1 |
| Mahapatra, M | 1 |
| Grillage, M | 1 |
| Atkinson, SN | 1 |
| Prescott, P | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Simethicone Pretreatment With Low-volume Polyethylene Glycol-3350 and Bisacodyl in an Effort to Improve Bowel Wall Visualization During Colonoscopy[NCT03410524] | Phase 3 | 250 participants (Actual) | Interventional | 2018-01-09 | Completed | ||
| Bowel Function After Minimally Invasive Hysterectomy: A Randomized Controlled Trial[NCT04263896] | Phase 4 | 101 participants (Anticipated) | Interventional | 2019-08-28 | Recruiting | ||
| Effect of Preoperative Fiber on Postoperative Bowel Function[NCT04882995] | 84 participants (Actual) | Interventional | 2019-05-13 | Completed | |||
| Effect of Prunes on Gastrointestinal Function After Gynecological Surgery: A Randomized Controlled Trial[NCT03523715] | Phase 4 | 77 participants (Actual) | Interventional | 2017-11-30 | Terminated (stopped due to Difficulty in recruiting participants) | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
Pain captured with visual analog scale with 0 being no pain and 10 being worst pain (NCT04882995)
Timeframe: Within 7 days
| Intervention | score on a scale (Median) |
|---|---|
| Intervention - Received Fiber | 2.0 |
| Control - Did Not Receive Fiber | 2.0 |
Date and time of first bowel movement captured via postoperative bowel diary (NCT04882995)
Timeframe: Within 7 days
| Intervention | hours (Mean) |
|---|---|
| Intervention - Received Fiber | 66.5 |
| Control - Did Not Receive Fiber | 68.3 |
The number of participants who had a bowel movement in the post operative study follow up (NCT03523715)
Timeframe: 5 days
| Intervention | Participants (Count of Participants) |
|---|---|
| Prunes | 26 |
| Control | 17 |
Likert scale from 0 to 10 in which higher values indicate more pain (NCT03523715)
Timeframe: 3 days
| Intervention | Likert scale 0-100 (Median) |
|---|---|
| Prunes | 60 |
| Control | 40 |
The number of participants who used any laxatives (besides the prunes and stool softeners) during the study period. (NCT03523715)
Timeframe: 3 days
| Intervention | Participants (Count of Participants) |
|---|---|
| Prunes | 7 |
| Control | 6 |
Likert scale from 0 to 10 in which higher values indicate more satisfaction (NCT03523715)
Timeframe: 3 day
| Intervention | Likert scale 0-100 (Median) |
|---|---|
| Prunes | 100 |
| Control | 80 |
Likert scale from 0 to 10 in which higher levels indicate more satisfaction (NCT03523715)
Timeframe: 3 days
| Intervention | Likert scale 0-100 (Median) |
|---|---|
| Prunes | 100 |
| Control | 100 |
Bristol Stool chart in which stool consistency is described as type 1 to 7 with higher values indicating more liquid stool (NCT03523715)
Timeframe: 3 days
| Intervention | Bristol Stool Scale (Median) |
|---|---|
| Prunes | 3 |
| Control | 4 |
Time to first bowel movement after surgery (NCT03523715)
Timeframe: 3 days
| Intervention | hours post surgery (Mean) |
|---|---|
| Prunes | 57.6 |
| Control | 53.8 |
1 review available for citric acid, anhydrous and Constipation
| Article | Year |
|---|---|
Fatal Hypermagnesemia Due to Laxative Use.
Topics: Acute Kidney Injury; Citric Acid; Constipation; Fatal Outcome; Female; Humans; Laxatives; Magnesium; | 2018 |
7 trials available for citric acid, anhydrous and Constipation
| Article | Year |
|---|---|
2-Litre polyethylene glycol-citrate-simethicone plus bisacodyl versus 4-litre polyethylene glycol as preparation for colonoscopy in chronic constipation.
Topics: Aged; Bisacodyl; Cathartics; Chronic Disease; Citric Acid; Colon; Colonoscopy; Constipation; Female; | 2015 |
The use of senna with docusate for postoperative constipation after pelvic reconstructive surgery: a randomized, double-blind, placebo-controlled trial.
Topics: Citric Acid; Constipation; Dioctyl Sulfosuccinic Acid; Double-Blind Method; Gynecologic Surgical Pro | 2010 |
The use of senna with docusate for postoperative constipation after pelvic reconstructive surgery: a randomized, double-blind, placebo-controlled trial.
Topics: Citric Acid; Constipation; Dioctyl Sulfosuccinic Acid; Double-Blind Method; Gynecologic Surgical Pro | 2010 |
The use of senna with docusate for postoperative constipation after pelvic reconstructive surgery: a randomized, double-blind, placebo-controlled trial.
Topics: Citric Acid; Constipation; Dioctyl Sulfosuccinic Acid; Double-Blind Method; Gynecologic Surgical Pro | 2010 |
The use of senna with docusate for postoperative constipation after pelvic reconstructive surgery: a randomized, double-blind, placebo-controlled trial.
Topics: Citric Acid; Constipation; Dioctyl Sulfosuccinic Acid; Double-Blind Method; Gynecologic Surgical Pro | 2010 |
The use of senna with docusate for postoperative constipation after pelvic reconstructive surgery: a randomized, double-blind, placebo-controlled trial.
Topics: Citric Acid; Constipation; Dioctyl Sulfosuccinic Acid; Double-Blind Method; Gynecologic Surgical Pro | 2010 |
The use of senna with docusate for postoperative constipation after pelvic reconstructive surgery: a randomized, double-blind, placebo-controlled trial.
Topics: Citric Acid; Constipation; Dioctyl Sulfosuccinic Acid; Double-Blind Method; Gynecologic Surgical Pro | 2010 |
The use of senna with docusate for postoperative constipation after pelvic reconstructive surgery: a randomized, double-blind, placebo-controlled trial.
Topics: Citric Acid; Constipation; Dioctyl Sulfosuccinic Acid; Double-Blind Method; Gynecologic Surgical Pro | 2010 |
The use of senna with docusate for postoperative constipation after pelvic reconstructive surgery: a randomized, double-blind, placebo-controlled trial.
Topics: Citric Acid; Constipation; Dioctyl Sulfosuccinic Acid; Double-Blind Method; Gynecologic Surgical Pro | 2010 |
The use of senna with docusate for postoperative constipation after pelvic reconstructive surgery: a randomized, double-blind, placebo-controlled trial.
Topics: Citric Acid; Constipation; Dioctyl Sulfosuccinic Acid; Double-Blind Method; Gynecologic Surgical Pro | 2010 |
Prospective randomized crossover trial comparing fibre with lactulose in the treatment of idiopathic chronic constipation.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Chronic Disease; Citric Acid; Constipation; Cross-Over S | 2006 |
Randomised clinical trial of a laxative alone versus a laxative and a bulking agent after primary repair of obstetric anal sphincter injury.
Topics: Adult; Anal Canal; Cathartics; Citric Acid; Constipation; Drug Combinations; Drug Therapy, Combinati | 2007 |
The effect of oral vancomycin on chronic idiopathic constipation.
Topics: Administration, Oral; Adult; Breath Tests; Citrates; Citric Acid; Constipation; Defecation; Dietary | 1995 |
The influence of ispaghula husk on bowel habit.
Topics: Adolescent; Adult; Cathartics; Citric Acid; Constipation; Defecation; Drug Combinations; Feces; Fema | 1998 |
An open, randomised, parallel group study of lactulose versus ispaghula in the treatment of chronic constipation in adults.
Topics: Bicarbonates; Chronic Disease; Citrates; Citric Acid; Constipation; Drug Combinations; Humans; Lactu | 1991 |
9 other studies available for citric acid, anhydrous and Constipation
| Article | Year |
|---|---|
Citric Acid-Enriched Extract of Ripe
Topics: Animals; Aquaporin 3; Citric Acid; Constipation; Laxatives; Loperamide; Prostaglandins; Prostaglandi | 2022 |
An Infant With Vomiting, Constipation, and Weight Loss.
Topics: Calcitriol; Citric Acid; Constipation; Cysteamine; Cystinosis; Diagnosis, Differential; Fanconi Synd | 2020 |
Pediatric constipation in the emergency department: evaluation, treatment, and outcomes.
Topics: Abdominal Pain; Child; Child, Preschool; Citric Acid; Constipation; Diagnostic Imaging; Emergency Se | 2014 |
A pilot study on the efficacy of Picolax given as a four-week course for the treatment of refractory constipation.
Topics: Adult; Cathartics; Chronic Disease; Citrates; Citric Acid; Cohort Studies; Constipation; Drug Combin | 2012 |
Lethal iatrogenic hypermagnesemia.
Topics: Aged; Cathartics; Citric Acid; Constipation; Humans; Iatrogenic Disease; Male; Organometallic Compou | 2002 |
Hypermagnesemia induced by massive cathartic ingestion in an elderly woman without pre-existing renal dysfunction.
Topics: Administration, Oral; Aged; Blood Pressure; Cathartics; Citric Acid; Constipation; Electrocardiograp | 2005 |
A study of bulking agents in elderly patients.
Topics: Aged; Bicarbonates; Cellulose; Citrates; Citric Acid; Constipation; Dietary Fiber; Drug Combinations | 1980 |
Hypermagnesemia-induced paralytic ileus.
Topics: Aged; Citrates; Citric Acid; Constipation; Female; Humans; Intestinal Pseudo-Obstruction; Intestines | 1994 |
Cathartic-induced life threatening hypermagnesemia in a 90-year-old woman with apparent normal renal function.
Topics: Aged; Aged, 80 and over; Cathartics; Citric Acid; Colectomy; Colitis, Ischemic; Colonic Diseases; Co | 1999 |