Page last updated: 2024-10-17

citric acid, anhydrous and Catheter-Associated Infections

citric acid, anhydrous has been researched along with Catheter-Associated Infections in 31 studies

Citric Acid: A key intermediate in metabolism. It is an acid compound found in citrus fruits. The salts of citric acid (citrates) can be used as anticoagulants due to their calcium chelating ability.
citric acid : A tricarboxylic acid that is propane-1,2,3-tricarboxylic acid bearing a hydroxy substituent at position 2. It is an important metabolite in the pathway of all aerobic organisms.

Research Excerpts

ExcerptRelevanceReference
"In taurolidine-treated patients, the CRBSI rate per 1000 catheter days decreased from 4."1.48Strategies to Reduce Catheter-Related Bloodstream Infections in Pediatric Patients Receiving Home Parenteral Nutrition: The Efficacy of Taurolidine-Citrate Prophylactic-Locking. ( Goulet, O; Lambe, C; Poisson, C; Talbotec, C, 2018)

Research

Studies (31)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's2 (6.45)29.6817
2010's18 (58.06)24.3611
2020's11 (35.48)2.80

Authors

AuthorsStudies
van Roeden, S1
van Oevelen, M1
Abrahams, AC1
Dekker, FW1
Rotmans, JI1
Meijvis, SCA1
Abdel-Fattah, M1
Johnson, D1
Constable, L1
Thomas, R1
Cotton, S1
Tripathee, S1
Cooper, D1
Boran, S1
Dimitropoulos, K1
Evans, S1
Granitsiotis, P1
Hashim, H1
Kilonzo, M1
Larcombe, J1
Little, P1
MacLennan, S1
Murchie, P1
Myint, PK1
N'Dow, J1
Norrie, J1
Omar, MI1
Paterson, C1
Scotland, G1
Thiruchelvam, N1
MacLennan, G1
Wang, Y1
Sun, X1
Boucley, I1
Dargent, A1
Andreu, P1
Roudaut, JB1
Aptel, F1
Labruyère, M1
Jacquier, M1
Cransac, A1
Quenot, JP1
van den Bosch, CH1
Loeffen, Y1
van der Steeg, AFW1
van der Bruggen, JT1
Frakking, FNJ1
Fiocco, M1
van de Ven, CP1
Wijnen, MHWA1
van de Wetering, MD1
Ait Hammou Taleb, MH1
Mahmutovic, M1
Michot, N1
Malgras, A1
Nguyen-Thi, PL1
Quilliot, D1
Ornowska, M1
Smithman, J1
Reynolds, S1
Jiménez Hernández, M1
Soriano, A2
Filella, X1
Calvo, M1
Coll, E1
Rebled, JM1
Poch, E1
Graterol, F1
Compte, MT1
Maduell, F2
Fontsere, N2
Hussein, WF1
Gomez, N1
Sun, SJ1
Yu, J1
Yang, F1
Ajuria, M1
Abra, GE1
Schiller, B2
Ezzat, H1
Elsharkawy, M1
Rezk, K1
Mohsen, R1
Mansour, A1
Emara, A1
Hemmelgarn, BR1
Manns, BJ1
Soroka, SD1
Levin, A1
MacRae, J1
Tennankore, K1
Wilson, JS1
Weaver, RG1
Ravani, P1
Quinn, RR1
Tonelli, M1
Kiaii, M1
Mossop, P1
Scott-Douglas, N1
Lambe, C1
Poisson, C1
Talbotec, C1
Goulet, O1
Clark, JE1
Graham, N1
Kleidon, T1
Ullman, A1
Girardot, T1
Monard, C1
Rimmelé, T1
Vargas-Cruz, N1
Reitzel, RA1
Rosenblatt, J1
Chaftari, AM1
Wilson Dib, R1
Hachem, R1
Kontoyiannis, DP1
Raad, II1
Bueloni, TNV1
Marchi, D1
Caetano, C1
de Souza Cavalcante, R1
Mendes Amaral, ML1
Ponce, D1
Chong, CY1
Ong, RY1
Seah, VX1
Tan, NW1
Chan, MY1
Soh, SY1
Ong, C1
Lim, AS1
Thoon, KC1
Niyyar, VD1
Lok, CE1
Zhao, Y1
Li, Z1
Zhang, L1
Yang, J1
Yang, Y1
Tang, Y1
Fu, P1
Carney, EF1
Erb, S1
Widmer, AF1
Tschudin-Sutter, S1
Neff, U1
Fischer, M1
Dickenmann, M1
Grosse, P1
Cardozo, C1
Donate, J1
Muros, M1
Pons, M1
Mensa, J1
Campistol, JM1
Navarro-González, JF1
Passero, BA1
Zappone, P1
Lee, HE1
Novak, C1
Maceira, EL1
Naber, M1
Zhang, J1
Wang, B1
Li, R1
Ge, L1
Chen, KH1
Tian, J1
Steczko, J1
Ash, SR1
Nivens, DE1
Brewer, L1
Winger, RK1
Broomfield, RJ1
Morgan, SD1
Khan, A1
Stickler, DJ1
Venditto, M1
du Montcel, ST1
Robert, J1
Trystam, D1
Dighiero, J1
Hue, D1
Bessette, C1
Deray, G1
Mercadal, L1
Filiopoulos, V1
Hadjiyannakos, D1
Koutis, I1
Trompouki, S1
Micha, T1
Lazarou, D1
Vlassopoulos, D1
Parikh, S1
Nijmeh, R1
Van Cleef, S1
Timmerman, S1
Bhatt, UY1
Agarwal, AK1
Moran, J1
Sun, S1
Khababa, I1
Pedan, A1
Doss, S1
Silva, J1
Antunes, J1
Carvalho, T1
Ponce, P1

Clinical Trials (5)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
The Use of Tetrasodium EDTA Catheter Lock Solution for Patients on Home Parenteral Nutrition: Ease of Use and Cost Analysis[NCT04067245]20 participants (Anticipated)Interventional2019-04-01Recruiting
Prospective, Randomized, Controlled Trial Evaluating the Efficacy of a Lock-therapy With a Solution of Taurolidine/Citrate (TauroLock) vs Standard Saline Solution for the Primary Prevention of Catheter-related Infections (CLI) in Adult Patients Wtih a Non[NCT02279121]162 participants (Actual)Interventional2014-11-30Completed
Bicarbonate vs Heparin Catheter Lock in Chronic Hemodialysis Patients[NCT04054128]Phase 460 participants (Actual)Interventional2019-09-11Active, not recruiting
Evaluation of the Efficacy of Prophylactic Topical Gentamicin in Tunnelled Catheters for Hemodialysis: a Randomized, Double-blind Clinical Trial[NCT04967859]Phase 190 participants (Actual)Interventional2018-07-01Completed
Sodium Citrate 4% Locking Solution for Children Requiring Home Parenteral Nutrition[NCT04756427]Phase 41 participants (Actual)Interventional2022-03-28Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

8 reviews available for citric acid, anhydrous and Catheter-Associated Infections

ArticleYear
Reevaluation of lock solutions for Central venous catheters in hemodialysis: a narrative review.
    Renal failure, 2022, Volume: 44, Issue:1

    Topics: Anti-Bacterial Agents; Anticoagulants; Catheter-Related Infections; Catheterization, Central Venous;

2022
Systematic review of locking solutions for non-tunneled hemodialysis catheters.
    Hemodialysis international. International Symposium on Home Hemodialysis, 2023, Volume: 27, Issue:1

    Topics: Adult; Catheter-Related Infections; Catheterization; Catheters, Indwelling; Central Venous Catheters

2023
Effectiveness of salvage catheters in home parenteral nutrition: A single-center study and systematic literature review.
    Clinical nutrition ESPEN, 2023, Volume: 56

    Topics: Adult; Anti-Bacterial Agents; Catheter-Related Infections; Central Venous Catheters; Citrates; Citri

2023
Locking solutions for prevention of central venous access device complications in the adult critical care population: A systematic review.
    PloS one, 2023, Volume: 18, Issue:10

    Topics: Adolescent; Adult; Catheter-Related Infections; Catheterization, Peripheral; Central Venous Catheter

2023
Dialysis catheters in the ICU: selection, insertion and maintenance.
    Current opinion in critical care, 2018, Volume: 24, Issue:6

    Topics: Catheter-Related Infections; Catheterization, Central Venous; Central Venous Catheters; Citric Acid;

2018
Pros and cons of catheter lock solutions.
    Current opinion in nephrology and hypertension, 2013, Volume: 22, Issue:6

    Topics: Anti-Bacterial Agents; Bacteremia; Catheter-Related Infections; Catheterization, Central Venous; Cit

2013
Citrate versus heparin lock for hemodialysis catheters: a systematic review and meta-analysis of randomized controlled trials.
    American journal of kidney diseases : the official journal of the National Kidney Foundation, 2014, Volume: 63, Issue:3

    Topics: Anticoagulants; Catheter-Related Infections; Central Venous Catheters; Citric Acid; Heparin; Humans;

2014
Citrate versus heparin lock for hemodialysis catheters: a systematic review and meta-analysis of randomized controlled trials.
    American journal of kidney diseases : the official journal of the National Kidney Foundation, 2014, Volume: 63, Issue:3

    Topics: Anticoagulants; Catheter-Related Infections; Central Venous Catheters; Citric Acid; Heparin; Humans;

2014
Citrate versus heparin lock for hemodialysis catheters: a systematic review and meta-analysis of randomized controlled trials.
    American journal of kidney diseases : the official journal of the National Kidney Foundation, 2014, Volume: 63, Issue:3

    Topics: Anticoagulants; Catheter-Related Infections; Central Venous Catheters; Citric Acid; Heparin; Humans;

2014
Citrate versus heparin lock for hemodialysis catheters: a systematic review and meta-analysis of randomized controlled trials.
    American journal of kidney diseases : the official journal of the National Kidney Foundation, 2014, Volume: 63, Issue:3

    Topics: Anticoagulants; Catheter-Related Infections; Central Venous Catheters; Citric Acid; Heparin; Humans;

2014
Citrate versus heparin lock for hemodialysis catheters: a systematic review and meta-analysis of randomized controlled trials.
    American journal of kidney diseases : the official journal of the National Kidney Foundation, 2014, Volume: 63, Issue:3

    Topics: Anticoagulants; Catheter-Related Infections; Central Venous Catheters; Citric Acid; Heparin; Humans;

2014
Citrate versus heparin lock for hemodialysis catheters: a systematic review and meta-analysis of randomized controlled trials.
    American journal of kidney diseases : the official journal of the National Kidney Foundation, 2014, Volume: 63, Issue:3

    Topics: Anticoagulants; Catheter-Related Infections; Central Venous Catheters; Citric Acid; Heparin; Humans;

2014
Citrate versus heparin lock for hemodialysis catheters: a systematic review and meta-analysis of randomized controlled trials.
    American journal of kidney diseases : the official journal of the National Kidney Foundation, 2014, Volume: 63, Issue:3

    Topics: Anticoagulants; Catheter-Related Infections; Central Venous Catheters; Citric Acid; Heparin; Humans;

2014
Citrate versus heparin lock for hemodialysis catheters: a systematic review and meta-analysis of randomized controlled trials.
    American journal of kidney diseases : the official journal of the National Kidney Foundation, 2014, Volume: 63, Issue:3

    Topics: Anticoagulants; Catheter-Related Infections; Central Venous Catheters; Citric Acid; Heparin; Humans;

2014
Citrate versus heparin lock for hemodialysis catheters: a systematic review and meta-analysis of randomized controlled trials.
    American journal of kidney diseases : the official journal of the National Kidney Foundation, 2014, Volume: 63, Issue:3

    Topics: Anticoagulants; Catheter-Related Infections; Central Venous Catheters; Citric Acid; Heparin; Humans;

2014
Citrate versus heparin lock for hemodialysis catheters: a systematic review and meta-analysis of randomized controlled trials.
    American journal of kidney diseases : the official journal of the National Kidney Foundation, 2014, Volume: 63, Issue:3

    Topics: Anticoagulants; Catheter-Related Infections; Central Venous Catheters; Citric Acid; Heparin; Humans;

2014
Citrate versus heparin lock for hemodialysis catheters: a systematic review and meta-analysis of randomized controlled trials.
    American journal of kidney diseases : the official journal of the National Kidney Foundation, 2014, Volume: 63, Issue:3

    Topics: Anticoagulants; Catheter-Related Infections; Central Venous Catheters; Citric Acid; Heparin; Humans;

2014
Citrate versus heparin lock for hemodialysis catheters: a systematic review and meta-analysis of randomized controlled trials.
    American journal of kidney diseases : the official journal of the National Kidney Foundation, 2014, Volume: 63, Issue:3

    Topics: Anticoagulants; Catheter-Related Infections; Central Venous Catheters; Citric Acid; Heparin; Humans;

2014
Citrate versus heparin lock for hemodialysis catheters: a systematic review and meta-analysis of randomized controlled trials.
    American journal of kidney diseases : the official journal of the National Kidney Foundation, 2014, Volume: 63, Issue:3

    Topics: Anticoagulants; Catheter-Related Infections; Central Venous Catheters; Citric Acid; Heparin; Humans;

2014
Citrate versus heparin lock for hemodialysis catheters: a systematic review and meta-analysis of randomized controlled trials.
    American journal of kidney diseases : the official journal of the National Kidney Foundation, 2014, Volume: 63, Issue:3

    Topics: Anticoagulants; Catheter-Related Infections; Central Venous Catheters; Citric Acid; Heparin; Humans;

2014
Citrate versus heparin lock for hemodialysis catheters: a systematic review and meta-analysis of randomized controlled trials.
    American journal of kidney diseases : the official journal of the National Kidney Foundation, 2014, Volume: 63, Issue:3

    Topics: Anticoagulants; Catheter-Related Infections; Central Venous Catheters; Citric Acid; Heparin; Humans;

2014
Citrate versus heparin lock for hemodialysis catheters: a systematic review and meta-analysis of randomized controlled trials.
    American journal of kidney diseases : the official journal of the National Kidney Foundation, 2014, Volume: 63, Issue:3

    Topics: Anticoagulants; Catheter-Related Infections; Central Venous Catheters; Citric Acid; Heparin; Humans;

2014
Does antimicrobial lock solution reduce catheter-related infections in hemodialysis patients with central venous catheters? A Bayesian network meta-analysis.
    International urology and nephrology, 2017, Volume: 49, Issue:4

    Topics: Adult; Anti-Infective Agents; Anticoagulants; Bayes Theorem; Catheter-Related Infections; Central Ve

2017

Trials

8 trials available for citric acid, anhydrous and Catheter-Associated Infections

ArticleYear
Randomised controlled trial comparing the clinical and cost-effectiveness of various washout policies versus no washout policy in preventing catheter associated complications in adults living with long-term catheters: study protocol for the CATHETER II st
    Trials, 2022, Aug-04, Volume: 23, Issue:1

    Topics: Adult; Catheter-Related Infections; Catheters, Indwelling; Citric Acid; Cost-Benefit Analysis; Femal

2022
CATERPILLAR-study protocol: an assessor-blinded randomised controlled trial comparing taurolidine-citrate-heparin to heparin-only lock solutions for the prevention of central line-associated bloodstream infections in paediatric oncology patients.
    BMJ open, 2023, 03-21, Volume: 13, Issue:3

    Topics: Catheter-Related Infections; Central Venous Catheters; Child; Citrates; Citric Acid; Heparin; Humans

2023
Effect of taurolidine citrate and unfractionated heparin on inflammatory state and dialysis adequacy in hemodialysis patients.
    The journal of vascular access, 2023, Volume: 24, Issue:1

    Topics: Anticoagulants; C-Reactive Protein; Catheter-Related Infections; Central Venous Catheters; Citrates;

2023
Cefazolin-gentamicin versus taurolidine-citrate for the prevention of infection in tunneled central catheters in hemodialysis patients: A quasi-experimental trial.
    International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases, 2019, Volume: 85

    Topics: Adult; Aged; Anti-Bacterial Agents; Catheter-Related Infections; Cefazolin; Central Venous Catheters

2019
Taurolidine-citrate lock solution for the prevention of central line-associated bloodstream infection in paediatric haematology-oncology and gastrointestinal failure patients with high baseline central-line associated bloodstream infection rates.
    Journal of paediatrics and child health, 2020, Volume: 56, Issue:1

    Topics: Adolescent; Bacteremia; Catheter-Related Infections; Catheterization, Central Venous; Central Venous

2020
Approaches to prolong the use of uncuffed hemodialysis catheters: results of a randomized trial.
    American journal of nephrology, 2011, Volume: 33, Issue:3

    Topics: Adult; Aged; Aged, 80 and over; Anti-Infective Agents; Anticoagulants; Catheter-Related Infections;

2011
A randomized trial comparing gentamicin/citrate and heparin locks for central venous catheters in maintenance hemodialysis patients.
    American journal of kidney diseases : the official journal of the National Kidney Foundation, 2012, Volume: 59, Issue:1

    Topics: Anti-Bacterial Agents; Anticoagulants; Catheter-Related Infections; Catheterization, Central Venous;

2012
Efficacy of preventing hemodialysis catheter infections with citrate lock.
    Hemodialysis international. International Symposium on Home Hemodialysis, 2012, Volume: 16, Issue:4

    Topics: Aged; Anti-Bacterial Agents; Catheter-Related Infections; Catheterization; Catheters, Indwelling; Ci

2012

Other Studies

15 other studies available for citric acid, anhydrous and Catheter-Associated Infections

ArticleYear
The best solution down the line: an observational study on taurolidine- versus citrate-based lock solutions for central venous catheters in hemodialysis patients.
    BMC nephrology, 2021, 09-13, Volume: 22, Issue:1

    Topics: Aged; Anticoagulants; Catheter-Related Infections; Catheters, Indwelling; Central Venous Catheters;

2021
Impact of locking solutions on conditioning biofilm formation in tunnelled haemodialysis catheters and inflammatory response activation.
    The journal of vascular access, 2021, Volume: 22, Issue:3

    Topics: Adult; Aged; Aged, 80 and over; Anti-Infective Agents; Anticoagulants; Biofilms; Catheter-Related In

2021
Use of a gentamicin-citrate lock leads to lower catheter-related bloodstream infection rates and reduced cost of care in hemodialysis patients.
    Hemodialysis international. International Symposium on Home Hemodialysis, 2021, Volume: 25, Issue:1

    Topics: Catheter-Related Infections; Catheterization, Central Venous; Central Venous Catheters; Citrates; Ci

2021
Effectiveness and Cost of Weekly Recombinant Tissue Plasminogen Activator Hemodialysis Catheter Locking Solution.
    Clinical journal of the American Society of Nephrology : CJASN, 2018, 03-07, Volume: 13, Issue:3

    Topics: Aged; Aged, 80 and over; Anticoagulants; Bacteremia; Catheter Obstruction; Catheter-Related Infectio

2018
Strategies to Reduce Catheter-Related Bloodstream Infections in Pediatric Patients Receiving Home Parenteral Nutrition: The Efficacy of Taurolidine-Citrate Prophylactic-Locking.
    JPEN. Journal of parenteral and enteral nutrition, 2018, Volume: 42, Issue:6

    Topics: Anti-Infective Agents; Calcium Chelating Agents; Catheter-Related Infections; Child; Child, Preschoo

2018
Taurolidine-Citrate Line Locks Prevent Recurrent Central Line-Associated Bloodstream Infection in Pediatric Patients.
    The Pediatric infectious disease journal, 2019, Volume: 38, Issue:1

    Topics: Adolescent; Anti-Infective Agents, Local; Bacteremia; Catheter-Related Infections; Catheterization,

2019
Nitroglycerin-Citrate-Ethanol Catheter Lock Solution Is Highly Effective for
    Antimicrobial agents and chemotherapy, 2019, Volume: 63, Issue:7

    Topics: Amphotericin B; Anidulafungin; Antifungal Agents; Biofilms; Candida; Caspofungin; Catheter-Related I

2019
Dialysis: Efficacy of catheter lock solutions.
    Nature reviews. Nephrology, 2014, Volume: 10, Issue:1

    Topics: Catheter-Related Infections; Central Venous Catheters; Citric Acid; Heparin; Humans; Randomized Cont

2014
Impact of different catheter lock strategies on bacterial colonization of permanent central venous hemodialysis catheters.
    Infection control and hospital epidemiology, 2013, Volume: 34, Issue:12

    Topics: Adult; Aged; Aged, 80 and over; Anticoagulants; Catheter-Related Infections; Catheters, Indwelling;

2013
Tunneled catheters with taurolidine-citrate-heparin lock solution significantly improve the inflammatory profile of hemodialysis patients.
    Antimicrobial agents and chemotherapy, 2014, Volume: 58, Issue:7

    Topics: Adult; Aged; Aged, 80 and over; Anti-Bacterial Agents; Anticoagulants; C-Reactive Protein; Catheter-

2014
Citrate versus heparin for apheresis catheter locks: an efficacy analysis.
    Journal of clinical apheresis, 2015, Volume: 30, Issue:1

    Topics: Anticoagulants; Blood Component Removal; Catheter-Related Infections; Catheterization, Central Venou

2015
Microbial inactivation properties of a new antimicrobial/antithrombotic catheter lock solution (citrate/methylene blue/parabens).
    Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association, 2009, Volume: 24, Issue:6

    Topics: Anti-Infective Agents; Bacteremia; Bacteria; Biofilms; Catheter-Related Infections; Catheterization,

2009
Crystalline bacterial biofilm formation on urinary catheters by urease-producing urinary tract pathogens: a simple method of control.
    Journal of medical microbiology, 2009, Volume: 58, Issue:Pt 10

    Topics: Bacterial Physiological Phenomena; Biofilms; Catheter-Related Infections; Citric Acid; Crystallizati

2009
Effect of catheter-lock solutions on catheter-related infection and inflammatory syndrome in hemodialysis patients: heparin versus citrate 46% versus heparin/gentamicin.
    Blood purification, 2010, Volume: 29, Issue:3

    Topics: Aged; Anti-Bacterial Agents; C-Reactive Protein; Catheter-Related Infections; Catheterization, Centr

2010
Catheter outcomes in the short-term inpatient setting: a controlled quality improvement study comparing citrate and heparin lock.
    Seminars in dialysis, 2012, Volume: 25, Issue:3

    Topics: Anticoagulants; Catheter-Related Infections; Catheters, Indwelling; Citric Acid; Female; Follow-Up S

2012
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