citric acid, anhydrous has been researched along with Carcinoma, Ovarian Epithelial in 2 studies
Citric Acid: A key intermediate in metabolism. It is an acid compound found in citrus fruits. The salts of citric acid (citrates) can be used as anticoagulants due to their calcium chelating ability.
citric acid : A tricarboxylic acid that is propane-1,2,3-tricarboxylic acid bearing a hydroxy substituent at position 2. It is an important metabolite in the pathway of all aerobic organisms.
Carcinoma, Ovarian Epithelial: A malignant neoplasm that originates in cells on the surface EPITHELIUM of the ovary and is the most common form of ovarian cancer. There are five histologic subtypes: papillary serous, endometrioid, mucinous, clear cell, and transitional cell. Mutations in BRCA1, OPCML, PRKN, PIK3CA, AKT1, CTNNB1, RRAS2, and CDH1 genes are associated with this cancer.
| Excerpt | Relevance | Reference |
|---|---|---|
| "This study elucidated that CA induces ovarian cancer cell death through classical and non-classical pyroptosis pathways, which may be beneficial as an ovarian cancer therapy." | 1.72 | Citric acid of ovarian cancer metabolite induces pyroptosis via the caspase-4/TXNIP-NLRP3-GSDMD pathway in ovarian cancer. ( Peng, C; Qian, W; Shen, S; Wang, T; Wang, X; Yin, Y; Zhao, S, 2022) |
| "MT19c reduced ovarian cancer growth in xenograft and syngeneic animal models without causing hypercalcemia or acute toxicity." | 1.38 | Efficacy of a non-hypercalcemic vitamin-D2 derived anti-cancer agent (MT19c) and inhibition of fatty acid synthesis in an ovarian cancer xenograft model. ( Arnold, LA; Brard, L; Brodsky, A; Chu, SR; DePaepe, ME; Horan, TC; Kawar, N; Kim, KK; Lange, TS; Mao, Q; Moore, RG; Padbury, JF; Robinson, K; Shen, TL; Singh, RK; Uzun, A; Yano, N, 2012) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (50.00) | 24.3611 |
| 2020's | 1 (50.00) | 2.80 |
| Authors | Studies |
|---|---|
| Wang, X | 1 |
| Yin, Y | 1 |
| Qian, W | 1 |
| Peng, C | 1 |
| Shen, S | 1 |
| Wang, T | 1 |
| Zhao, S | 1 |
| Moore, RG | 1 |
| Lange, TS | 1 |
| Robinson, K | 1 |
| Kim, KK | 1 |
| Uzun, A | 1 |
| Horan, TC | 1 |
| Kawar, N | 1 |
| Yano, N | 1 |
| Chu, SR | 1 |
| Mao, Q | 1 |
| Brard, L | 1 |
| DePaepe, ME | 1 |
| Padbury, JF | 1 |
| Arnold, LA | 1 |
| Brodsky, A | 1 |
| Shen, TL | 1 |
| Singh, RK | 1 |
2 other studies available for citric acid, anhydrous and Carcinoma, Ovarian Epithelial
| Article | Year |
|---|---|
Citric acid of ovarian cancer metabolite induces pyroptosis via the caspase-4/TXNIP-NLRP3-GSDMD pathway in ovarian cancer.
Topics: Carcinoma, Ovarian Epithelial; Carrier Proteins; Caspase 1; Citric Acid; Female; Humans; Inflammasom | 2022 |
Efficacy of a non-hypercalcemic vitamin-D2 derived anti-cancer agent (MT19c) and inhibition of fatty acid synthesis in an ovarian cancer xenograft model.
Topics: Amino Acid Sequence; Animals; Antineoplastic Agents; Calcium; Carcinoma, Ovarian Epithelial; Cell Li | 2012 |