Page last updated: 2024-10-17

citric acid, anhydrous and Carcinoma, Anaplastic

citric acid, anhydrous has been researched along with Carcinoma, Anaplastic in 13 studies

Citric Acid: A key intermediate in metabolism. It is an acid compound found in citrus fruits. The salts of citric acid (citrates) can be used as anticoagulants due to their calcium chelating ability.
citric acid : A tricarboxylic acid that is propane-1,2,3-tricarboxylic acid bearing a hydroxy substituent at position 2. It is an important metabolite in the pathway of all aerobic organisms.

Research Excerpts

ExcerptRelevanceReference
"One of significant characteristics of prostate cancer is slow glycolysis and low FDG avidity."2.43Fatty acid oxidation is a dominant bioenergetic pathway in prostate cancer. ( Liu, Y, 2006)
"New colorectal tumors were noted significantly more frequently (P = ."1.31Measurement of carcinoembryonic antigen in colonic effluent as a high-risk marker for colorectal carcinoma. ( Akedo, I; Iseki, K; Ishiguro, S; Ishikawa, H; Kaji, I; Narahara, H; Otani, T; Suzuki, T; Uedo, N, 2000)
"Ten breast carcinomas were immunostained for estrogen and progesterone receptors (ER and PR), Ki-67/ MIB 1, p27/Kip-1, and Bcl-2 after MAR, LTAR with enzymatic pretreatment, or no antigen recovery."1.31Methods of antigen recovery vary in their usefulness in unmasking specific antigens in immunohistochemistry. ( Frost, AR; Grizzle, WE; Sparks, D, 2000)
"Specific activities of follicular adenomas are rather heterogeneous."1.27Phosphofructokinase in normal thyroid tissue and thyroid neoplasms. ( der Kinderen, PJ; Rijksen, G; Staal, GE; van der Heijden, MC; van Unnik, JA; Verhagen, JN, 1986)

Research

Studies (13)

TimeframeStudies, this research(%)All Research%
pre-19904 (30.77)18.7374
1990's3 (23.08)18.2507
2000's5 (38.46)29.6817
2010's1 (7.69)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
He, X1
Yan, B1
Liu, S2
Jia, J1
Lai, W1
Xin, X1
Tang, CE1
Luo, D1
Tan, T1
Jiang, Y1
Shi, Y1
Liu, Y2
Xiao, D1
Chen, L1
Mao, C1
Yin, G1
Cheng, Y1
Fan, J1
Cao, Y1
Muegge, K1
Tao, Y1
LUTWAK-MANN, C1
Kumar, R1
Kumar, M1
Jagannathan, NR1
Gupta, NP1
Hemal, AK1
ROTTINO, A1
HOFFMANN, GT1
BRONDOLO, B1
Juang, HH1
Shi, SR1
Chaiwun, B1
Young, L1
Cote, RJ1
Taylor, CR1
Kazumoto, T1
Mitsuhashi, N1
Hayakawa, K1
Yonome, I1
Niibe, H1
Uedo, N1
Ishikawa, H1
Narahara, H1
Akedo, I1
Iseki, K1
Kaji, I1
Ishiguro, S1
Suzuki, T1
Otani, T1
Frost, AR1
Sparks, D1
Grizzle, WE1
Ward, FT1
Anderson, JH1
Jelinek, J1
Anderson, DW1
van der Heijden, MC1
Verhagen, JN1
Rijksen, G1
der Kinderen, PJ1
van Unnik, JA1
Staal, GE1
Nakayama, M1
Miyamoto, Y1
Hasegawa, R1
Kure, F1
Saito, A1
Kimoto, K1
Matsuno, H1
Yamashita, M1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Radiosensitization With a COX-2 Inhibitor (Celecoxib), With Chemoradiation for Cancer of the Head and Neck[NCT00581971]Phase 1/Phase 230 participants (Actual)Interventional2002-09-30Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trial Outcomes

Response as Evaluated by Recurrence of Diseases

Evaluate the response to concurrent celecoxib, carboplatin, paclitaxel, and radiotherapy in the treatment of locally advanced SSC of the head and neck. Response is determined by local control only, local and distant metastasis, distant metastasis only, second primary, and surgical salvage. (NCT00581971)
Timeframe: 2 years from end of treatment (Radiation therapy)

InterventionParticipants (Number)
Local Control OnlyLocal Control and Distant MetastasisDistant Metastatsis OnlySecondary Primary - Site UnknownSurgical Salvage
Recurrence62123

Toxicity of Celecoxib With Concurrent Weekly Chemotherapy and Radiotherapy in the Treatment of Locally Advanced or Recurrent Squamous Cell Carcinoma of the Head and Neck.

Particpants experiencing Acute Toxicities > Grade 3 (NCT00581971)
Timeframe: 2 years from radiation therapy

Interventionparticipants (Number)
HematologicDermatitisMucositis/Dysphagia
Acute Toxicity12716

Reviews

1 review available for citric acid, anhydrous and Carcinoma, Anaplastic

ArticleYear
Fatty acid oxidation is a dominant bioenergetic pathway in prostate cancer.
    Prostate cancer and prostatic diseases, 2006, Volume: 9, Issue:3

    Topics: Carcinoma; Citric Acid; Dietary Fats; Energy Metabolism; Fatty Acids; Humans; Lipid Metabolism; Male

2006

Other Studies

12 other studies available for citric acid, anhydrous and Carcinoma, Anaplastic

ArticleYear
Chromatin Remodeling Factor LSH Drives Cancer Progression by Suppressing the Activity of Fumarate Hydratase.
    Cancer research, 2016, 10-01, Volume: 76, Issue:19

    Topics: Animals; Carcinoma; Cell Line, Tumor; Chromatin Assembly and Disassembly; Citric Acid; Citric Acid C

2016
CITRIC ACID IN METASTASIZING CARCINOMA OF THE PROSTATE GLAND.
    National Cancer Institute monograph, 1963, Volume: 12

    Topics: Carcinoma; Citrates; Citric Acid; Humans; Male; Metabolism; Neoplasm Metastasis; Neoplasms; Prostati

1963
Proton magnetic resonance spectroscopy with a body coil in the diagnosis of carcinoma prostate.
    Urological research, 2004, Volume: 32, Issue:1

    Topics: Adult; Aged; Aged, 80 and over; Carcinoma; Choline; Citric Acid; Creatine; Diagnosis, Differential;

2004
Serum citric acid in Hodgkin's disease, lymphoma and carcinoma.
    Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.), 1952, Volume: 80, Issue:2

    Topics: Carcinoma; Citrates; Citric Acid; Hodgkin Disease; Humans; Lymphoma

1952
Cyclic adenosine 3',5'-monosphosphate mediate prolactin regulation of mitochondrial aconitase in human prostate carcinoma cells.
    Molecular and cellular endocrinology, 2004, Apr-30, Volume: 219, Issue:1-2

    Topics: Aconitate Hydratase; Carcinoma; Cell Line; Citric Acid; Cyclic AMP; Gene Expression Regulation, Neop

2004
Antigen retrieval technique utilizing citrate buffer or urea solution for immunohistochemical demonstration of androgen receptor in formalin-fixed paraffin sections.
    The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society, 1993, Volume: 41, Issue:11

    Topics: Antigens, Neoplasm; Buffers; Carcinoma; Citrates; Citric Acid; Frozen Sections; Humans; Immunoenzyme

1993
Radioimmunodetection of lung cancer with IMACIS-1, I-131 labeled monoclonal antibodies to CEA and CA19-9. Comparison of accumulations in irradiated and non-irradiated site.
    Annals of nuclear medicine, 1993, Volume: 7, Issue:1

    Topics: Adenocarcinoma; Adenocarcinoma, Mucinous; Aged; Aged, 80 and over; Antibodies, Monoclonal; Carcinoma

1993
Measurement of carcinoembryonic antigen in colonic effluent as a high-risk marker for colorectal carcinoma.
    Cancer detection and prevention, 2000, Volume: 24, Issue:3

    Topics: Age Factors; Aged; Aged, 80 and over; Biomarkers, Tumor; Carcinoembryonic Antigen; Carcinoma; Cathar

2000
Methods of antigen recovery vary in their usefulness in unmasking specific antigens in immunohistochemistry.
    Applied immunohistochemistry & molecular morphology : AIMM, 2000, Volume: 8, Issue:3

    Topics: Antigens; Antigens, Nuclear; Breast Neoplasms; Carcinoma; Carcinoma, Ductal, Breast; Cell Cycle Prot

2000
Localization of metastatic adrenal cortical carcinoma with Ga-67.
    Clinical nuclear medicine, 1991, Volume: 16, Issue:2

    Topics: Adrenal Cortex Neoplasms; Adult; Carcinoma; Citrates; Citric Acid; Gallium Radioisotopes; Humans; Lu

1991
Phosphofructokinase in normal thyroid tissue and thyroid neoplasms.
    Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine, 1986, Volume: 7, Issue:1

    Topics: Adenoma; Carcinoma; Citrates; Citric Acid; Humans; Isoenzymes; Kinetics; Phosphofructokinase-1; Thyr

1986
[A case of acinar cell carcinoma of the pancreas with increased uptake of 67Ga citrate].
    Rinsho hoshasen. Clinical radiography, 1988, Volume: 33, Issue:8

    Topics: Carcinoma; Citrates; Citric Acid; Humans; Male; Middle Aged; Pancreatic Neoplasms; Radionuclide Imag

1988