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citric acid, anhydrous and Bacteremia

citric acid, anhydrous has been researched along with Bacteremia in 10 studies

Citric Acid: A key intermediate in metabolism. It is an acid compound found in citrus fruits. The salts of citric acid (citrates) can be used as anticoagulants due to their calcium chelating ability.
citric acid : A tricarboxylic acid that is propane-1,2,3-tricarboxylic acid bearing a hydroxy substituent at position 2. It is an important metabolite in the pathway of all aerobic organisms.

Bacteremia: The presence of viable bacteria circulating in the blood. Fever, chills, tachycardia, and tachypnea are common acute manifestations of bacteremia. The majority of cases are seen in already hospitalized patients, most of whom have underlying diseases or procedures which render their bloodstreams susceptible to invasion.

Research Excerpts

ExcerptRelevanceReference
"Taurolidine-citrate use did not decrease all-cause bacteremia and was associated with a greater need for thrombolytic treatment."9.14A randomized double-blind controlled trial of taurolidine-citrate catheter locks for the prevention of bacteremia in patients treated with hemodialysis. ( Al-Sayed, T; Bhat, R; Cheesbrough, JS; Curry, A; Diggle, P; Ebah, L; Heap, M; Millband, N; Mitra, S; Saxena, R; Schulz, M; Solomon, LR; Waterhouse, D, 2010)
"Preliminary evidence from some studies suggests that taurolidine-citrate locks decrease catheter-related bacteremia (CRB), which is a major cause of morbidity and mortality in patients using intravascular catheters."8.90Preventing catheter-related bacteremia with taurolidine-citrate catheter locks: a systematic review and meta-analysis. ( Chen, L; Deng, J; Liu, H; Wu, Y; Yuan, L, 2014)
"Taurolidine-citrate use did not decrease all-cause bacteremia and was associated with a greater need for thrombolytic treatment."5.14A randomized double-blind controlled trial of taurolidine-citrate catheter locks for the prevention of bacteremia in patients treated with hemodialysis. ( Al-Sayed, T; Bhat, R; Cheesbrough, JS; Curry, A; Diggle, P; Ebah, L; Heap, M; Millband, N; Mitra, S; Saxena, R; Schulz, M; Solomon, LR; Waterhouse, D, 2010)
"Preliminary evidence from some studies suggests that taurolidine-citrate locks decrease catheter-related bacteremia (CRB), which is a major cause of morbidity and mortality in patients using intravascular catheters."4.90Preventing catheter-related bacteremia with taurolidine-citrate catheter locks: a systematic review and meta-analysis. ( Chen, L; Deng, J; Liu, H; Wu, Y; Yuan, L, 2014)

Research

Studies (10)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's2 (20.00)29.6817
2010's7 (70.00)24.3611
2020's1 (10.00)2.80

Authors

AuthorsStudies
Hemmelgarn, BR1
Manns, BJ1
Soroka, SD1
Levin, A1
MacRae, J1
Tennankore, K1
Wilson, JS1
Weaver, RG1
Ravani, P1
Quinn, RR1
Tonelli, M1
Kiaii, M1
Mossop, P1
Scott-Douglas, N1
Clark, JE1
Graham, N1
Kleidon, T1
Ullman, A1
Chong, CY1
Ong, RY1
Seah, VX1
Tan, NW1
Chan, MY1
Soh, SY1
Ong, C1
Lim, AS1
Thoon, KC1
Niyyar, VD1
Lok, CE1
Liu, H2
Deng, J1
Chen, L1
Yuan, L1
Wu, Y1
Murray, EC1
Deighan, C1
Geddes, C1
Thomson, PC1
Raad, II1
Fang, X1
Keutgen, XM1
Jiang, Y1
Sherertz, R1
Hachem, R1
Steczko, J1
Ash, SR1
Nivens, DE1
Brewer, L1
Winger, RK1
Solomon, LR1
Cheesbrough, JS1
Ebah, L1
Al-Sayed, T1
Heap, M1
Millband, N1
Waterhouse, D1
Mitra, S1
Curry, A1
Saxena, R1
Bhat, R1
Schulz, M1
Diggle, P1
Boszczowski, I1
Nóbrega de Almeida Júnior, J1
Peixoto de Miranda, EJ1
Pinheiro Freire, M1
Guimarães, T1
Chaves, CE1
Cais, DP1
Strabelli, TM1
Risek, CF1
Soares, RE1
Rossi, F1
Costa, SF1
Levin, AS1

Clinical Trials (2)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
A Pilot Study to Evaluate the Effect of Livionex on Reducing Plaque Accumulation and Improving Oral Health in Children[NCT04368533]78 participants (Actual)Interventional2019-02-08Completed
Prospective, Randomized, Controlled Trial Evaluating the Efficacy of a Lock-therapy With a Solution of Taurolidine/Citrate (TauroLock) vs Standard Saline Solution for the Primary Prevention of Catheter-related Infections (CLI) in Adult Patients Wtih a Non[NCT02279121]162 participants (Actual)Interventional2014-11-30Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

3 reviews available for citric acid, anhydrous and Bacteremia

ArticleYear
Pros and cons of catheter lock solutions.
    Current opinion in nephrology and hypertension, 2013, Volume: 22, Issue:6

    Topics: Anti-Bacterial Agents; Bacteremia; Catheter-Related Infections; Catheterization, Central Venous; Cit

2013
Preventing catheter-related bacteremia with taurolidine-citrate catheter locks: a systematic review and meta-analysis.
    Blood purification, 2014, Volume: 37, Issue:3

    Topics: Anti-Infective Agents; Anticoagulants; Bacteremia; Citric Acid; Female; Humans; Male; PubMed; Taurin

2014
The role of chelators in preventing biofilm formation and catheter-related bloodstream infections.
    Current opinion in infectious diseases, 2008, Volume: 21, Issue:4

    Topics: Anti-Bacterial Agents; Bacteremia; Bacterial Adhesion; Biofilms; Catheterization; Chelating Agents;

2008

Trials

2 trials available for citric acid, anhydrous and Bacteremia

ArticleYear
Taurolidine-citrate lock solution for the prevention of central line-associated bloodstream infection in paediatric haematology-oncology and gastrointestinal failure patients with high baseline central-line associated bloodstream infection rates.
    Journal of paediatrics and child health, 2020, Volume: 56, Issue:1

    Topics: Adolescent; Bacteremia; Catheter-Related Infections; Catheterization, Central Venous; Central Venous

2020
A randomized double-blind controlled trial of taurolidine-citrate catheter locks for the prevention of bacteremia in patients treated with hemodialysis.
    American journal of kidney diseases : the official journal of the National Kidney Foundation, 2010, Volume: 55, Issue:6

    Topics: Adult; Aged; Anti-Infective Agents; Anticoagulants; Bacteremia; Catheters, Indwelling; Citric Acid;

2010

Other Studies

5 other studies available for citric acid, anhydrous and Bacteremia

ArticleYear
Effectiveness and Cost of Weekly Recombinant Tissue Plasminogen Activator Hemodialysis Catheter Locking Solution.
    Clinical journal of the American Society of Nephrology : CJASN, 2018, 03-07, Volume: 13, Issue:3

    Topics: Aged; Aged, 80 and over; Anticoagulants; Bacteremia; Catheter Obstruction; Catheter-Related Infectio

2018
Taurolidine-Citrate Line Locks Prevent Recurrent Central Line-Associated Bloodstream Infection in Pediatric Patients.
    The Pediatric infectious disease journal, 2019, Volume: 38, Issue:1

    Topics: Adolescent; Anti-Infective Agents, Local; Bacteremia; Catheter-Related Infections; Catheterization,

2019
Taurolidine-citrate-heparin catheter lock solution reduces staphylococcal bacteraemia rates in haemodialysis patients.
    QJM : monthly journal of the Association of Physicians, 2014, Volume: 107, Issue:12

    Topics: Anti-Infective Agents; Anticoagulants; Bacteremia; Catheterization, Central Venous; Catheters, Indwe

2014
Microbial inactivation properties of a new antimicrobial/antithrombotic catheter lock solution (citrate/methylene blue/parabens).
    Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association, 2009, Volume: 24, Issue:6

    Topics: Anti-Infective Agents; Bacteremia; Bacteria; Biofilms; Catheter-Related Infections; Catheterization,

2009
Nosocomial outbreak of Pantoea agglomerans bacteraemia associated with contaminated anticoagulant citrate dextrose solution: new name, old bug?
    The Journal of hospital infection, 2012, Volume: 80, Issue:3

    Topics: Aged; Aged, 80 and over; Bacteremia; Bacterial Typing Techniques; Citric Acid; Cross Infection; Dise

2012