citric acid, anhydrous has been researched along with Aging in 63 studies
Citric Acid: A key intermediate in metabolism. It is an acid compound found in citrus fruits. The salts of citric acid (citrates) can be used as anticoagulants due to their calcium chelating ability.
citric acid : A tricarboxylic acid that is propane-1,2,3-tricarboxylic acid bearing a hydroxy substituent at position 2. It is an important metabolite in the pathway of all aerobic organisms.
Aging: The gradual irreversible changes in structure and function of an organism that occur as a result of the passage of time.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Evaluation of (1) age-related dietary trends over time and (2) factors involved in iron absorption leads to the hypothesis that the combination of citric acid and ascorbic acid (a synergistic pair of strong enhancers) is instrumental in causing a deleterious increase in iron load in aging populations." | 8.79 | Proposed role for a combination of citric acid and ascorbic acid in the production of dietary iron overload: a fundamental cause of disease. ( Crawford, RD, 1995) |
| " Evaluation of (1) age-related dietary trends over time and (2) factors involved in iron absorption leads to the hypothesis that the combination of citric acid and ascorbic acid (a synergistic pair of strong enhancers) is instrumental in causing a deleterious increase in iron load in aging populations." | 4.79 | Proposed role for a combination of citric acid and ascorbic acid in the production of dietary iron overload: a fundamental cause of disease. ( Crawford, RD, 1995) |
| " Lactic acid, EGCG, resveratrol, and retinol that can inhibit collagen synthesis effectively in a dose-dependent manner may be used for anti-fibrosis treatment purposes." | 3.74 | A rapid and sensitive screening system for human type I collagen with the aim of discovering potent anti-aging or anti-fibrotic compounds. ( Choo, HY; Hashem, MA; Jun, KY; Kwon, Y; Lee, E; Lim, S, 2008) |
| "The influence of aging on glucose and glutamine metabolism by isolated jejunal cells was studied using young (4 months) and aged (24 months) Fischer 344 male rats when fed ad libitum or fasted 48 h." | 3.69 | The TCA cycle as an oxidative and synthetic pathway is suppressed with aging in jejunal epithelial cells. ( Fleming, SE; Kight, CE, 1994) |
| "The risk of aspiration pneumonia in Parkinson's disease (PD) may be increased by sensory loss in the laryngopharynx and a reduced cough reflex." | 1.38 | Changes in chemosensitivity and mechanosensitivity in aging and Parkinson's disease. ( Anderson, T; Beckert, L; Huckabee, ML; Leow, LP, 2012) |
| "Although hypertension is a prevalent condition among the elderly, little is known with respect to the influence of hypertension on oral health and function." | 1.29 | Comparison of stimulated parotid salivary gland flow rates in normotensive and hypertensive persons. ( Brown, LJ; Ship, JA; Streckfus, CF; Wu, AJ, 1994) |
| "In a longitudinal study we determined the effect of animal age as well as Ca source and radiolabeling method on Ca bioavailability by measuring whole body 47Ca retention (WBR) in male Sprague-Dawley rats." | 1.29 | Effect of age, calcium source, and radiolabeling method on whole body 47Ca retention in the rat. ( Andon, MB; Kanerva, RL; Schulte, MC; Smith, KT, 1993) |
| "Mild dysgeusia may act as a masking stimulus that makes taste thresholds appear to be elevated, and this may be more common in the elderly than the young." | 1.28 | Taste. Robust across the age span? ( Bartoshuk, LM, 1989) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 24 (38.10) | 18.7374 |
| 1990's | 17 (26.98) | 18.2507 |
| 2000's | 14 (22.22) | 29.6817 |
| 2010's | 7 (11.11) | 24.3611 |
| 2020's | 1 (1.59) | 2.80 |
| Authors | Studies |
|---|---|
| Mycielska, ME | 1 |
| James, EN | 1 |
| Parkinson, EK | 2 |
| Halim, AA | 1 |
| Alsayed, B | 1 |
| Embarak, S | 1 |
| Yaseen, T | 1 |
| Dabbous, S | 1 |
| Fontaine, O | 1 |
| Dueluzeau, R | 1 |
| Raibaud, P | 1 |
| Chabanet, C | 1 |
| Popoff, MR | 1 |
| Badoual, J | 1 |
| Gabilan, JC | 1 |
| Andremont, A | 1 |
| Gómez, L | 1 |
| Andrés, S | 1 |
| Sánchez, J | 1 |
| Alonso, JM | 1 |
| Rey, J | 1 |
| López, F | 1 |
| Jiménez, A | 1 |
| Yan, Z | 1 |
| Zhou, L | 1 |
| Zhao, Y | 3 |
| Wang, J | 6 |
| Huang, L | 2 |
| Hu, K | 1 |
| Liu, H | 4 |
| Wang, H | 3 |
| Guo, Z | 1 |
| Song, Y | 1 |
| Huang, H | 4 |
| Yang, R | 1 |
| Owen, TW | 1 |
| Al-Kaysi, RO | 1 |
| Bardeen, CJ | 1 |
| Cheng, Q | 1 |
| Wu, S | 1 |
| Cheng, T | 1 |
| Zhou, X | 1 |
| Wang, B | 4 |
| Zhang, Q | 4 |
| Wu, X | 2 |
| Yao, Y | 3 |
| Ochiai, T | 1 |
| Ishiguro, H | 2 |
| Nakano, R | 2 |
| Kubota, Y | 2 |
| Hara, M | 1 |
| Sunada, K | 1 |
| Hashimoto, K | 1 |
| Kajioka, J | 1 |
| Fujishima, A | 1 |
| Jiao, J | 3 |
| Gai, QY | 3 |
| Wang, W | 2 |
| Zang, YP | 2 |
| Niu, LL | 2 |
| Fu, YJ | 3 |
| Wang, X | 4 |
| Yao, LP | 1 |
| Qin, QP | 1 |
| Wang, ZY | 1 |
| Liu, J | 4 |
| Aleksic Sabo, V | 1 |
| Knezevic, P | 1 |
| Borges-Argáez, R | 1 |
| Chan-Balan, R | 1 |
| Cetina-Montejo, L | 1 |
| Ayora-Talavera, G | 1 |
| Sansores-Peraza, P | 1 |
| Gómez-Carballo, J | 1 |
| Cáceres-Farfán, M | 1 |
| Jang, J | 1 |
| Akin, D | 1 |
| Bashir, R | 1 |
| Yu, Z | 1 |
| Zhu, J | 2 |
| Jiang, H | 1 |
| He, C | 2 |
| Xiao, Z | 1 |
| Xu, J | 2 |
| Sun, Q | 1 |
| Han, D | 1 |
| Lei, H | 1 |
| Zhao, K | 2 |
| Zhu, L | 1 |
| Li, X | 4 |
| Fu, H | 2 |
| Wilson, BK | 1 |
| Step, DL | 1 |
| Maxwell, CL | 1 |
| Gifford, CA | 1 |
| Richards, CJ | 1 |
| Krehbiel, CR | 1 |
| Warner, JM | 1 |
| Doerr, AJ | 1 |
| Erickson, GE | 1 |
| Guretzky, JA | 1 |
| Rasby, RJ | 1 |
| Watson, AK | 1 |
| Klopfenstein, TJ | 1 |
| Sun, Y | 4 |
| Liu, Z | 3 |
| Pham, TD | 1 |
| Lee, BK | 1 |
| Yang, FC | 1 |
| Wu, KH | 1 |
| Lin, WP | 1 |
| Hu, MK | 1 |
| Lin, L | 3 |
| Shao, J | 1 |
| Sun, M | 1 |
| Xu, G | 1 |
| Zhang, X | 6 |
| Xu, N | 1 |
| Wang, R | 1 |
| Liu, S | 1 |
| He, H | 1 |
| Dong, X | 2 |
| Yang, M | 2 |
| Yang, Q | 1 |
| Duan, S | 1 |
| Yu, Y | 2 |
| Han, J | 2 |
| Zhang, C | 3 |
| Chen, L | 2 |
| Yang, X | 1 |
| Li, W | 3 |
| Wang, T | 2 |
| Campbell, DA | 1 |
| Gao, K | 1 |
| Zager, RA | 1 |
| Johnson, ACM | 1 |
| Guillem, A | 1 |
| Keyser, J | 1 |
| Singh, B | 1 |
| Steubl, D | 1 |
| Schneider, MP | 1 |
| Meiselbach, H | 1 |
| Nadal, J | 1 |
| Schmid, MC | 1 |
| Saritas, T | 1 |
| Krane, V | 1 |
| Sommerer, C | 1 |
| Baid-Agrawal, S | 1 |
| Voelkl, J | 1 |
| Kotsis, F | 1 |
| Köttgen, A | 1 |
| Eckardt, KU | 1 |
| Scherberich, JE | 1 |
| Li, H | 4 |
| Yao, L | 2 |
| Sun, L | 3 |
| Zhu, Z | 1 |
| Naren, N | 1 |
| Zhang, XX | 2 |
| Gentile, GL | 1 |
| Rupert, AS | 1 |
| Carrasco, LI | 1 |
| Garcia, EM | 1 |
| Kumar, NG | 1 |
| Walsh, SW | 1 |
| Jefferson, KK | 1 |
| Guest, RL | 1 |
| Samé Guerra, D | 1 |
| Wissler, M | 1 |
| Grimm, J | 1 |
| Silhavy, TJ | 1 |
| Lee, JH | 2 |
| Yoo, JS | 1 |
| Kim, Y | 1 |
| Kim, JS | 2 |
| Lee, EJ | 1 |
| Roe, JH | 1 |
| Delorme, M | 1 |
| Bouchard, PA | 1 |
| Simon, M | 1 |
| Simard, S | 1 |
| Lellouche, F | 1 |
| D'Urzo, KA | 1 |
| Mok, F | 1 |
| D'Urzo, AD | 1 |
| Koneru, B | 1 |
| Lopez, G | 1 |
| Farooqi, A | 1 |
| Conkrite, KL | 1 |
| Nguyen, TH | 1 |
| Macha, SJ | 1 |
| Modi, A | 1 |
| Rokita, JL | 1 |
| Urias, E | 1 |
| Hindle, A | 1 |
| Davidson, H | 1 |
| Mccoy, K | 1 |
| Nance, J | 1 |
| Yazdani, V | 1 |
| Irwin, MS | 1 |
| Yang, S | 1 |
| Wheeler, DA | 1 |
| Maris, JM | 1 |
| Diskin, SJ | 1 |
| Reynolds, CP | 1 |
| Abhilash, L | 1 |
| Kalliyil, A | 1 |
| Sheeba, V | 1 |
| Hartley, AM | 2 |
| Meunier, B | 2 |
| Pinotsis, N | 1 |
| Maréchal, A | 2 |
| Xu, JY | 1 |
| Genko, N | 1 |
| Haraux, F | 1 |
| Rich, PR | 1 |
| Kamalanathan, M | 1 |
| Doyle, SM | 1 |
| Xu, C | 1 |
| Achberger, AM | 1 |
| Wade, TL | 1 |
| Schwehr, K | 1 |
| Santschi, PH | 1 |
| Sylvan, JB | 1 |
| Quigg, A | 1 |
| Leong, W | 1 |
| Xu, W | 2 |
| Gao, S | 1 |
| Zhai, X | 1 |
| Wang, C | 2 |
| Gilson, E | 1 |
| Ye, J | 1 |
| Lu, Y | 1 |
| Yan, R | 1 |
| Zhang, Y | 7 |
| Hu, Z | 1 |
| You, Q | 1 |
| Cai, Q | 1 |
| Yang, D | 1 |
| Gu, S | 1 |
| Dai, H | 1 |
| Zhao, X | 1 |
| Gui, C | 1 |
| Gui, J | 1 |
| Wu, PK | 1 |
| Hong, SK | 1 |
| Starenki, D | 1 |
| Oshima, K | 1 |
| Shao, H | 1 |
| Gestwicki, JE | 1 |
| Tsai, S | 1 |
| Park, JI | 1 |
| Wang, Y | 7 |
| Zhao, R | 1 |
| Gu, Z | 1 |
| Dong, C | 2 |
| Guo, G | 1 |
| Li, L | 4 |
| Barrett, HE | 1 |
| Meester, EJ | 1 |
| van Gaalen, K | 1 |
| van der Heiden, K | 1 |
| Krenning, BJ | 1 |
| Beekman, FJ | 1 |
| de Blois, E | 1 |
| de Swart, J | 1 |
| Verhagen, HJ | 1 |
| Maina, T | 1 |
| Nock, BA | 1 |
| Norenberg, JP | 1 |
| de Jong, M | 1 |
| Gijsen, FJH | 1 |
| Bernsen, MR | 1 |
| Martínez-Milla, J | 1 |
| Galán-Arriola, C | 1 |
| Carnero, M | 1 |
| Cobiella, J | 1 |
| Pérez-Camargo, D | 1 |
| Bautista-Hernández, V | 1 |
| Rigol, M | 1 |
| Solanes, N | 1 |
| Villena-Gutierrez, R | 1 |
| Lobo, M | 1 |
| Mateo, J | 1 |
| Vilchez-Tschischke, JP | 1 |
| Salinas, B | 1 |
| Cussó, L | 1 |
| López, GJ | 1 |
| Fuster, V | 1 |
| Desco, M | 1 |
| Sanchez-González, J | 1 |
| Ibanez, B | 1 |
| van den Berg, P | 1 |
| Schweitzer, DH | 1 |
| van Haard, PMM | 1 |
| Geusens, PP | 1 |
| van den Bergh, JP | 1 |
| Zhu, X | 1 |
| Huang, X | 2 |
| Xu, H | 2 |
| Yang, G | 2 |
| Lin, Z | 1 |
| Salem, HF | 1 |
| Nafady, MM | 1 |
| Kharshoum, RM | 1 |
| Abd El-Ghafar, OA | 1 |
| Farouk, HO | 1 |
| Domiciano, D | 1 |
| Nery, FC | 1 |
| de Carvalho, PA | 1 |
| Prudente, DO | 1 |
| de Souza, LB | 1 |
| Chalfun-Júnior, A | 1 |
| Paiva, R | 1 |
| Marchiori, PER | 1 |
| Lu, M | 2 |
| An, Z | 1 |
| Jiang, J | 2 |
| Li, J | 7 |
| Du, S | 1 |
| Zhou, H | 1 |
| Cui, J | 1 |
| Wu, W | 1 |
| Liu, Y | 7 |
| Song, J | 1 |
| Lian, Q | 1 |
| Uddin Ahmad, Z | 1 |
| Gang, DD | 1 |
| Konggidinata, MI | 1 |
| Gallo, AA | 1 |
| Zappi, ME | 1 |
| Yang, TWW | 1 |
| Johari, Y | 1 |
| Burton, PR | 1 |
| Earnest, A | 1 |
| Shaw, K | 1 |
| Hare, JL | 1 |
| Brown, WA | 1 |
| Kim, GA | 1 |
| Han, S | 1 |
| Choi, GH | 1 |
| Choi, J | 1 |
| Lim, YS | 1 |
| Gallo, A | 1 |
| Cancelli, C | 1 |
| Ceron, E | 1 |
| Covino, M | 1 |
| Capoluongo, E | 1 |
| Pocino, K | 1 |
| Ianiro, G | 1 |
| Cammarota, G | 1 |
| Gasbarrini, A | 1 |
| Montalto, M | 1 |
| Somasundar, Y | 1 |
| Lu, IC | 1 |
| Mills, MR | 1 |
| Qian, LY | 1 |
| Olivares, X | 1 |
| Ryabov, AD | 1 |
| Collins, TJ | 1 |
| Zhao, L | 1 |
| Doddipatla, S | 1 |
| Thomas, AM | 1 |
| Nikolayev, AA | 1 |
| Galimova, GR | 1 |
| Azyazov, VN | 1 |
| Mebel, AM | 1 |
| Kaiser, RI | 1 |
| Guo, S | 1 |
| Yang, P | 1 |
| Yu, X | 2 |
| Wu, Y | 2 |
| Zhang, H | 1 |
| Yu, B | 2 |
| Han, B | 1 |
| George, MW | 1 |
| Moor, MB | 1 |
| Bonny, O | 1 |
| Langenberg, E | 1 |
| Paik, H | 1 |
| Smith, EH | 1 |
| Nair, HP | 1 |
| Hanke, I | 1 |
| Ganschow, S | 1 |
| Catalan, G | 1 |
| Domingo, N | 1 |
| Schlom, DG | 1 |
| Assefa, MK | 1 |
| Wu, G | 2 |
| Hayton, TW | 1 |
| Becker, B | 1 |
| Enikeev, D | 1 |
| Netsch, C | 1 |
| Gross, AJ | 1 |
| Laukhtina, E | 1 |
| Glybochko, P | 1 |
| Rapoport, L | 1 |
| Herrmann, TRW | 1 |
| Taratkin, M | 1 |
| Dai, W | 1 |
| Shi, J | 2 |
| Carreno, J | 1 |
| Kloner, RA | 1 |
| Pickersgill, NA | 1 |
| Vetter, JM | 1 |
| Kim, EH | 1 |
| Cope, SJ | 1 |
| Du, K | 1 |
| Venkatesh, R | 1 |
| Giardina, JD | 1 |
| Saad, NES | 1 |
| Bhayani, SB | 1 |
| Figenshau, RS | 1 |
| Eriksson, J | 1 |
| Landfeldt, E | 1 |
| Ireland, S | 1 |
| Jackson, C | 1 |
| Wyatt, E | 1 |
| Gaudig, M | 1 |
| Stancill, JS | 1 |
| Happ, JT | 1 |
| Broniowska, KA | 1 |
| Hogg, N | 1 |
| Corbett, JA | 1 |
| Tang, LF | 1 |
| Bi, YL | 1 |
| Fan, Y | 2 |
| Sun, YB | 1 |
| Wang, AL | 1 |
| Xiao, BH | 1 |
| Wang, LF | 1 |
| Qiu, SW | 1 |
| Guo, SW | 1 |
| Wáng, YXJ | 1 |
| Sun, J | 2 |
| Chu, S | 1 |
| Pan, Q | 1 |
| Li, D | 2 |
| Zheng, S | 2 |
| Ma, L | 1 |
| Wang, L | 3 |
| Hu, T | 1 |
| Wang, F | 1 |
| Han, Z | 1 |
| Yin, Z | 1 |
| Ge, X | 1 |
| Xie, K | 1 |
| Lei, P | 1 |
| Dias-Santagata, D | 1 |
| Lennerz, JK | 1 |
| Sadow, PM | 1 |
| Frazier, RP | 1 |
| Govinda Raju, S | 1 |
| Henry, D | 1 |
| Chung, T | 1 |
| Kherani, J | 1 |
| Rothenberg, SM | 1 |
| Wirth, LJ | 1 |
| Marti, CN | 1 |
| Choi, NG | 1 |
| Bae, SJ | 1 |
| Ni, L | 1 |
| Luo, X | 1 |
| Dai, T | 1 |
| Yang, Y | 3 |
| Lee, R | 1 |
| Fleischer, AS | 1 |
| Wemhoff, AP | 1 |
| Ford, CR | 1 |
| Kleppinger, EL | 1 |
| Helms, K | 1 |
| Bush, AA | 1 |
| Luna-Abanto, J | 1 |
| García Ruiz, L | 1 |
| Laura Martinez, J | 1 |
| Álvarez Larraondo, M | 1 |
| Villoslada Terrones, V | 1 |
| Dukic, L | 1 |
| Maric, N | 1 |
| Simundic, AM | 1 |
| Chogtu, B | 1 |
| Ommurugan, B | 1 |
| Thomson, SR | 1 |
| Kalthur, SG | 1 |
| Benidir, M | 1 |
| El Massoudi, S | 1 |
| El Ghadraoui, L | 1 |
| Lazraq, A | 1 |
| Benjelloun, M | 1 |
| Errachidi, F | 1 |
| Cassar, M | 1 |
| Law, AD | 1 |
| Chow, ES | 1 |
| Giebultowicz, JM | 1 |
| Kretzschmar, D | 1 |
| Salonurmi, T | 1 |
| Nabil, H | 1 |
| Ronkainen, J | 1 |
| Hyötyläinen, T | 1 |
| Hautajärvi, H | 1 |
| Savolainen, MJ | 1 |
| Tolonen, A | 1 |
| Orešič, M | 1 |
| Känsäkoski, P | 1 |
| Rysä, J | 1 |
| Hakkola, J | 1 |
| Hukkanen, J | 1 |
| Zhu, N | 1 |
| Li, Y | 4 |
| Du, Q | 1 |
| Hao, P | 1 |
| Cao, X | 1 |
| Li, CX | 1 |
| Zhao, S | 1 |
| Luo, XM | 1 |
| Feng, JX | 1 |
| Gonzalez-Cotto, M | 1 |
| Guo, L | 1 |
| Karwan, M | 1 |
| Sen, SK | 1 |
| Barb, J | 1 |
| Collado, CJ | 1 |
| Elloumi, F | 1 |
| Palmieri, EM | 1 |
| Boelte, K | 1 |
| Kolodgie, FD | 1 |
| Finn, AV | 1 |
| Biesecker, LG | 1 |
| McVicar, DW | 1 |
| Qu, F | 1 |
| Deng, Z | 1 |
| Xie, Y | 2 |
| Tang, J | 3 |
| Chen, Z | 2 |
| Luo, W | 1 |
| Xiong, D | 1 |
| Zhao, D | 1 |
| Fang, J | 1 |
| Zhou, Z | 1 |
| Niu, PP | 1 |
| Song, B | 1 |
| Xu, YM | 1 |
| Zhang, Z | 2 |
| Qiu, N | 1 |
| Yin, J | 1 |
| Zhang, J | 3 |
| Guo, W | 1 |
| Liu, M | 2 |
| Liu, T | 2 |
| Chen, D | 5 |
| Luo, K | 1 |
| He, Z | 2 |
| Zheng, G | 1 |
| Xu, F | 1 |
| Sun, W | 1 |
| Yin, F | 1 |
| van Hest, JCM | 1 |
| Du, L | 2 |
| Shi, X | 1 |
| Kang, S | 1 |
| Duan, W | 1 |
| Zhang, S | 2 |
| Feng, J | 2 |
| Qi, N | 1 |
| Shen, G | 1 |
| Ren, H | 1 |
| Shang, Q | 1 |
| Zhao, W | 2 |
| Yang, Z | 2 |
| Jiang, X | 2 |
| Alame, M | 1 |
| Cornillot, E | 1 |
| Cacheux, V | 1 |
| Tosato, G | 1 |
| Four, M | 1 |
| De Oliveira, L | 1 |
| Gofflot, S | 1 |
| Delvenne, P | 1 |
| Turtoi, E | 1 |
| Cabello-Aguilar, S | 1 |
| Nishiyama, M | 1 |
| Turtoi, A | 1 |
| Costes-Martineau, V | 1 |
| Colinge, J | 1 |
| Guo, Q | 1 |
| Quan, M | 1 |
| Dong, J | 1 |
| Bai, J | 1 |
| Han, R | 1 |
| Cai, Y | 1 |
| Lv, YQ | 1 |
| Chen, Q | 1 |
| Lyu, HD | 1 |
| Deng, L | 1 |
| Zhou, D | 1 |
| Xiao, X | 1 |
| De Langhe, S | 1 |
| Billadeau, DD | 1 |
| Lou, Z | 1 |
| Zhang, JS | 1 |
| Xue, Z | 1 |
| Shen, XD | 1 |
| Gao, F | 1 |
| Busuttil, RW | 1 |
| Kupiec-Weglinski, JW | 1 |
| Ji, H | 1 |
| Otano, I | 1 |
| Alvarez, M | 1 |
| Minute, L | 1 |
| Ochoa, MC | 1 |
| Migueliz, I | 1 |
| Molina, C | 1 |
| Azpilikueta, A | 1 |
| de Andrea, CE | 1 |
| Etxeberria, I | 1 |
| Sanmamed, MF | 1 |
| Teijeira, Á | 1 |
| Berraondo, P | 1 |
| Melero, I | 1 |
| Zhong, Z | 1 |
| Xie, X | 1 |
| Yu, Q | 1 |
| Zhou, C | 1 |
| Liu, C | 2 |
| Liu, W | 1 |
| Chen, W | 1 |
| Yin, Y | 1 |
| Li, CW | 1 |
| Hsu, JL | 1 |
| Zhou, Q | 1 |
| Hu, B | 1 |
| Fu, P | 1 |
| Atyah, M | 1 |
| Ma, Q | 2 |
| Xu, Y | 1 |
| Dong, Q | 1 |
| Hung, MC | 1 |
| Ren, N | 1 |
| Huang, P | 1 |
| Liao, R | 1 |
| Chen, X | 3 |
| Cao, Q | 1 |
| Yuan, X | 1 |
| Nie, W | 1 |
| Yang, J | 2 |
| Shao, B | 1 |
| Ma, X | 1 |
| Bi, Z | 1 |
| Liang, X | 1 |
| Tie, Y | 1 |
| Mo, F | 1 |
| Xie, D | 1 |
| Wei, Y | 1 |
| Wei, X | 2 |
| Dokla, EME | 1 |
| Fang, CS | 1 |
| Chu, PC | 1 |
| Chang, CS | 1 |
| Abouzid, KAM | 1 |
| Chen, CS | 1 |
| Blaszczyk, R | 1 |
| Brzezinska, J | 1 |
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| Xin, Z | 1 |
| Himmelbauer, MK | 1 |
| Jones, JH | 1 |
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| Hesson, T | 1 |
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| Marcotte, DJ | 1 |
| Murugan, P | 1 |
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| Wu, AJ | 1 |
| Ship, JA | 1 |
| Brown, LJ | 1 |
| Fleming, SE | 1 |
| Kight, CE | 1 |
| Kanerva, RL | 1 |
| Schulte, MC | 1 |
| Smith, KT | 1 |
| Shern, RJ | 1 |
| Fox, PC | 2 |
| Li, SH | 1 |
| Johnson, P | 1 |
| Hammer, JL | 1 |
| Malik, P | 1 |
| McKenna, MC | 1 |
| Tildon, JT | 1 |
| Smith, AG | 1 |
| Hoppe, B | 1 |
| Langman, CB | 1 |
| Yeh, CK | 1 |
| Johnson, DA | 1 |
| Dodds, MW | 1 |
| Haden, ST | 1 |
| Brown, EM | 1 |
| Hurwitz, S | 1 |
| Scott, J | 1 |
| El-Hajj Fuleihan, G | 1 |
| Melnick, JZ | 1 |
| Preisig, PA | 1 |
| Alpern, RJ | 1 |
| Baum, M | 1 |
| Boling, SD | 1 |
| Douglas, MW | 1 |
| Snow, JL | 1 |
| Parsons, CM | 1 |
| Baker, DH | 1 |
| Mojet, J | 1 |
| Christ-Hazelhof, E | 1 |
| Heidema, J | 1 |
| Bell, JD | 1 |
| Sadler, PJ | 1 |
| Morris, VC | 1 |
| Levander, OA | 1 |
| Héritier, M | 1 |
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| Bailliez, Y | 1 |
| Treves, C | 1 |
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| Vincenzini, MT | 1 |
| Shalev, A | 1 |
| Laor, A | 1 |
| Laufer, D | 1 |
| Bartoshuk, LM | 1 |
| Koizumi, K | 1 |
| Uchiyama, G | 1 |
| Araki, T | 1 |
| Hihara, T | 1 |
| Ogata, H | 1 |
| Monzawa, S | 1 |
| Kachi, K | 1 |
| Matsusako, M | 1 |
| Bristow, J | 1 |
| Bier, DM | 1 |
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| Spencer, RP | 1 |
| Chauhan, J | 1 |
| Hawrysh, ZJ | 1 |
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| Aruldhas, MM | 1 |
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| Stecenko, AA | 1 |
| Hoyer, S | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Musculoskeletal Benefits of Bicarbonate in Older Adults - A Dose-Finding Trial[NCT01475214] | Phase 2 | 244 participants (Actual) | Interventional | 2012-01-31 | Completed | ||
| Effect of Stress-Busting Program on Caregivers' Quality of Life, Stress/Immunity Bio-markers, and Cellular Aging[NCT02844478] | 37 participants (Actual) | Interventional | 2016-09-30 | Completed | |||
| Impact of Infant Feeding on Newborn Metabolomic Profile[NCT01606683] | 30 participants (Actual) | Interventional | 2012-04-30 | Completed | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
Describe and compare changes in 24-hour urinary nitrogen in the low and high dose and KHCO3 group and in placebo. (NCT01475214)
Timeframe: 84 days
| Intervention | mmol/day (Mean) | |
|---|---|---|
| baseline 24-hr urine nitrogen | change in 24-hr urine nitrogen | |
| Inactive Capsule | 864 | -21.0 |
| Potassium Bicarbonate Higher Dose | 834 | -16.4 |
| Potassium Bicarbonate Low Dose | 769 | -29.4 |
Describe and compare changes in urinary N-telopeptide (NTX) across the placebo and Potassium Bicarbonate (KHCO3) doses. (NCT01475214)
Timeframe: 84 days
| Intervention | nmol/day (Mean) | |
|---|---|---|
| baseline 24-hr urinary NTX | change in NTX | |
| Inactive Placebo Capsule | 241 | -14 |
| Potassium Bicarbonate Higher Dose | 230 | -43 |
| Potassium Bicarbonate Low Dose | 240 | -53 |
4 reviews available for citric acid, anhydrous and Aging
| Article | Year |
|---|---|
Metabolic Alterations in Cellular Senescence: The Role of Citrate in Ageing and Age-Related Disease.
Topics: Aging; Animals; Cellular Senescence; Chromatin; Citric Acid; Inflammation; Mice | 2022 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Proposed role for a combination of citric acid and ascorbic acid in the production of dietary iron overload: a fundamental cause of disease.
Topics: Aging; Ascorbic Acid; Citrates; Citric Acid; Diet; Disease; Free Radicals; Heart Diseases; Humans; I | 1995 |
Supplementation trials with calcium citrate malate: evidence in favor of increasing the calcium RDA during childhood and adolescence.
Topics: Adolescent; Aging; Bone Development; Calcium; Calcium, Dietary; Child; Child, Preschool; Citrates; C | 1994 |
4 trials available for citric acid, anhydrous and Aging
| Article | Year |
|---|---|
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Association of Urinary Citrate With Acid-Base Status, Bone Resorption, and Calcium Excretion in Older Men and Women.
Topics: Acid-Base Equilibrium; Aged; Aged, 80 and over; Aging; Bicarbonates; Bone Remodeling; Bone Resorptio | 2018 |
Age differences in orofacial sensory thresholds.
Topics: Adult; Aged; Aged, 80 and over; Aging; Chin; Citric Acid; Cold Temperature; Face; Female; Hot Temper | 2010 |
Addition of cisapride shortens colonoscopy preparation with lavage in elderly patients.
Topics: Adult; Aged; Aging; Antacids; Anti-Ulcer Agents; Chromatography, High Pressure Liquid; Cisapride; Ci | 1994 |
56 other studies available for citric acid, anhydrous and Aging
| Article | Year |
|---|---|
The induction of the fibroblast extracellular senescence metabolome is a dynamic process.
Topics: Aging; Cells, Cultured; Cellular Senescence; Citric Acid; Cyclin-Dependent Kinase Inhibitor p16; DNA | 2018 |
The influence of female mice age on biodistribution and biocompatibility of citrate-coated magnetic nanoparticles.
Topics: Aging; Animals; Citric Acid; Coated Materials, Biocompatible; Female; Iron; Lung; Magnetite Nanopart | 2019 |
A rapid and sensitive screening system for human type I collagen with the aim of discovering potent anti-aging or anti-fibrotic compounds.
Topics: Aging; Ascorbic Acid; Cell Line; Citric Acid; Collagen Type I; Drug Evaluation, Preclinical; Enzyme- | 2008 |
Copper deficiency alters the neurochemical profile of developing rat brain.
Topics: Aging; Animals; Ascorbic Acid; Aspartic Acid; Brain; Brain Chemistry; Cerebellum; Citric Acid; Coppe | 2009 |
[Metabonomic profiling of plasma metabolites in Wistar rats to study the effect of aging by means of GC/TOFMS-based techniques].
Topics: Aconitic Acid; Adipates; Aging; alpha-Tocopherol; Animals; Biomarkers; Chromatography, Gas; Citric A | 2009 |
Age-related functional changes in gustatory and reward processing regions: An fMRI study.
Topics: Adult; Aged; Aging; Brain; Brain Mapping; Caffeine; Central Nervous System Stimulants; Citric Acid; | 2010 |
Changes in chemosensitivity and mechanosensitivity in aging and Parkinson's disease.
Topics: Adult; Aged; Aged, 80 and over; Aging; Citric Acid; Cough; Endoscopy; Female; Humans; Irritants; Mal | 2012 |
[BEHAVIOR OF CITRIC ACID IN THE BLOOD OF AGED SUBJECTS].
Topics: Adolescent; Aging; Biomedical Research; Blood Chemical Analysis; Child; Citrates; Citric Acid; Geria | 1964 |
CHANGES WITH AGING IN PROSTATIC FLUID: CITRIC ACID, ACID PHOSPHATASE AND LACTIC DEHYDROGENASE CONCENTRATION IN MAN.
Topics: Acid Phosphatase; Adolescent; Aging; Alanine Transaminase; Aspartate Aminotransferases; Biomedical R | 1964 |
THE ROLE OF CITRATE ON THE RESPIRATORY CONTROL OF ISOLATED RAT HEART SARCOSOMES.
Topics: Aging; Citrates; Citric Acid; Edetic Acid; Metabolism; Mitochondria; Mitochondria, Muscle; Muscles; | 1964 |
CHANGES WITH AGING IN PROSTATIC FLUID: CITRIC ACID, ACID PHOSPHATASE AND LACTIC DEHYDROGENASE CONCENTRATION IN MAN.
Topics: Acid Phosphatase; Adolescent; Aging; Alanine Transaminase; Aspartate Aminotransferases; Biochemical | 1965 |
Krebs cycle enzymes from livers of old mice are differentially regulated by caloric restriction.
Topics: Aging; Animals; Aspartic Acid; Caloric Restriction; Citric Acid; Citric Acid Cycle; Glutamic Acid; K | 2004 |
The life-extending gene Indy encodes an exchanger for Krebs-cycle intermediates.
Topics: 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid; Aging; Animals; Antiporters; Carbon Radioisotopes; | 2006 |
A method for evaluating the fluctuations in the intensity of substance transport between blood and bones in the predominant direction.
Topics: Aging; Animals; Biochemistry; Biological Transport; Bone and Bones; Carbon Radioisotopes; Carbonates | 2006 |
Normative values for the assessment of gustatory function using liquid tastants.
Topics: Adolescent; Adult; Age Factors; Aged; Aging; Beverages; Citric Acid; Female; Humans; Male; Middle Ag | 2007 |
Laryngeal stimulation by an acid solution in the pre-term lamb.
Topics: Aging; Animals; Animals, Newborn; Citric Acid; Disease Models, Animal; Gastroesophageal Reflux; Hydr | 2008 |
The metabolites citrate, myo-inositol, and spermine are potential age-independent markers of prostate cancer in human expressed prostatic secretions.
Topics: Adult; Aged; Aging; Area Under Curve; Biomarkers, Tumor; Body Fluids; Citric Acid; Humans; Inositol; | 2008 |
Role of the electrophilic lipid peroxidation product 4-hydroxynonenal in the development and maintenance of obesity in mice.
Topics: Acetyl-CoA Carboxylase; Aconitate Hydratase; Aging; Aldehydes; Animals; Antigens, CD; Antigens, Diff | 2008 |
Whole-saliva secretion rates in old and young healthy subjects.
Topics: Adult; Aged; Aging; Citrates; Citric Acid; Female; Humans; Male; Saliva; Secretory Rate; Stimulation | 1984 |
Superior laryngeal nerve response patterns to chemical stimulation of sheep epiglottis.
Topics: Aging; Animals; Chemoreceptor Cells; Citrates; Citric Acid; Electric Conductivity; Epiglottis; Laryn | 1983 |
Killing of Listeria monocytogens by conventional and germfree rat sera.
Topics: Aging; Animals; Blood Bactericidal Activity; Blood Proteins; Calcium Chloride; Citrates; Citric Acid | 1981 |
Equilibrium density gradient analysis of erythrocytes from normal humans and patients with Duchenne muscular dystrophy.
Topics: Adolescent; Adult; Aged; Aging; Anticoagulants; Centrifugation, Density Gradient; Child; Child, Pres | 1983 |
Taste thresholds: quality specific variation with human aging.
Topics: Adult; Aged; Aging; Analysis of Variance; Citrates; Citric Acid; Female; Humans; Male; Middle Aged; | 1982 |
Sodium citrate premedication in elective caesarean section patients.
Topics: Adult; Aging; Antacids; Cesarean Section; Citrates; Citric Acid; Female; Gastroesophageal Reflux; Hu | 1982 |
Mitochondrial/cytosolic carbon transfer in the developing rat brain.
Topics: Acetoacetates; Aging; Animals; Biological Transport; Brain; Carbon; Citrates; Citric Acid; Cytosol; | 1981 |
Age and sex effects on taste of sucrose, NaCl, citric acid and caffeine.
Topics: Adult; Aged; Aging; Caffeine; Citrates; Citric Acid; Discrimination, Psychological; Humans; Sodium C | 1981 |
Impact of age and environment on somatic mutation at the hprt gene of T lymphocytes in humans.
Topics: Adult; Aging; Anticoagulants; Citrates; Citric Acid; Clone Cells; Environmental Exposure; Female; Gl | 1995 |
Recombinant human insulin-like growth factor 1 (rh-IGF-1) stimulates erythropoiesis in adult, but not in newborn mice.
Topics: Aging; Animals; Animals, Newborn; Citrates; Citric Acid; Drug Combinations; Erythroid Precursor Cell | 1994 |
Comparison of stimulated parotid salivary gland flow rates in normotensive and hypertensive persons.
Topics: Aged; Aging; Analysis of Variance; Baltimore; Black People; Blood Pressure; Citrates; Citric Acid; F | 1994 |
The TCA cycle as an oxidative and synthetic pathway is suppressed with aging in jejunal epithelial cells.
Topics: Aging; Animals; Cells, Cultured; Citrates; Citric Acid; Citric Acid Cycle; Fasting; Glucose; Glutami | 1994 |
Effect of age, calcium source, and radiolabeling method on whole body 47Ca retention in the rat.
Topics: Administration, Oral; Aging; Analysis of Variance; Animals; Biological Availability; Calcium; Calciu | 1993 |
Influence of age on the secretory rates of the human minor salivary glands and whole saliva.
Topics: Adult; Age Factors; Aged; Aged, 80 and over; Aging; Citrates; Citric Acid; Female; Humans; Male; Mid | 1993 |
Cardiac and skeletal muscle enzyme levels in hypertensive and aging rats.
Topics: 3-Hydroxyacyl CoA Dehydrogenases; Aging; Animals; Calpain; Citrates; Citric Acid; Fatty Acids; Glyco | 1993 |
Regulation of malate dehydrogenases from neonatal, adolescent, and mature rat brain.
Topics: Aging; Animals; Animals, Newborn; Brain; Citrates; Citric Acid; Cytosol; Homeostasis; Ketoglutaric A | 1993 |
Do fruit juices stimulate iron absorption and toxicity?
Topics: Aging; Ascorbic Acid; Beverages; Bone Diseases; Citrates; Citric Acid; Diabetes Mellitus; Drug Syner | 1995 |
Hypocitraturia in patients with urolithiasis.
Topics: Aging; Biomarkers; Child; Child, Preschool; Citric Acid; Female; Humans; Infant; Male; Urinary Calcu | 1997 |
Impact of aging on human salivary gland function: a community-based study.
Topics: Adult; Aged; Aging; Body Constitution; Citric Acid; Community Medicine; Energy Intake; Female; Human | 1998 |
The effects of age and gender on parathyroid hormone dynamics.
Topics: Adult; Aged; Aging; Analysis of Variance; Area Under Curve; Calcium; Citric Acid; Female; Humans; Ma | 2000 |
Renal citrate metabolism and urinary citrate excretion in the infant rat.
Topics: Aging; Animals; Animals, Newborn; Carrier Proteins; Citric Acid; Diet; Kidney; Male; Potassium; Rats | 2000 |
Citric acid does not improve phosphorus utilization in laying hens fed a corn-soybean meal diet.
Topics: Aging; Animal Nutritional Physiological Phenomena; Animals; Biological Availability; Chickens; Citri | 2000 |
Taste perception with age: generic or specific losses in threshold sensitivity to the five basic tastes?
Topics: Acetic Acid; Adult; Age Factors; Aged; Aging; Citric Acid; Female; Food Preferences; Humans; Inosine | 2001 |
Effect of aging and diet on proton NMR spectra of rat urine.
Topics: Aging; Animals; Caseins; Citrates; Citric Acid; Creatinine; Diet; Glycoproteins; Hippurates; Hydroge | 1991 |
Differentiation of odontoblasts in mouse dental papillae recombined with normal or chemically-treated dentinal matrices.
Topics: Aging; Animals; Cell Differentiation; Citrates; Citric Acid; Dental Papilla; Dentin; Dentinogenesis; | 1990 |
Changes in metabolite transport by small intestine and kidney of young and old rats.
Topics: Aging; Animals; Aspartic Acid; Citrates; Citric Acid; Glucose; In Vitro Techniques; Intestine, Small | 1990 |
The salivary flow rate and composition of whole and parotid resting and stimulated saliva in young and old healthy subjects.
Topics: Adult; Aged; Aging; Amylases; Citrates; Citric Acid; Electrolytes; Female; Humans; Male; Middle Aged | 1986 |
Taste. Robust across the age span?
Topics: Adult; Aged; Aging; Anesthesia, Local; Citrates; Citric Acid; Dysgeusia; Female; Humans; Male; Middl | 1989 |
[Detectability of metastatic bone tumor by Ga-67 scintigraphy].
Topics: Aged; Aging; Bone and Bones; Bone Neoplasms; Citrates; Citric Acid; Female; Gallium Radioisotopes; H | 1989 |
Regulation of adult and fetal myocardial phosphofructokinase. Relief of cooperativity and competition between fructose 2,6-bisphosphate, ATP, and citrate.
Topics: Adenosine Triphosphate; Aging; Animals; Binding, Competitive; Citrates; Citric Acid; Fructosediphosp | 1987 |
Nuclear medicine studies of aging--V. Uptake of 67Ga and 111In in the femoral vessels.
Topics: Adult; Aged; Aging; Citrates; Citric Acid; Femur; Humans; Hydroxyquinolines; Indium Radioisotopes; L | 1988 |
Suprathreshold sour taste intensity and pleasantness perception with age.
Topics: Adult; Aged; Aged, 80 and over; Aging; Citrates; Citric Acid; Female; Humans; Male; Middle Aged; Psy | 1988 |
Age-related differences in the pleasantness of chemosensory stimuli.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Aging; Citrates; Citric Acid; Food Preferences; Humans; | 1986 |
Secretion of antimicrobial proteins from the parotid glands of different aged healthy persons.
Topics: Adult; Aged; Aging; Anti-Infective Agents; Citrates; Citric Acid; Female; Humans; Immunoglobulin A, | 1987 |
Interaction of sex steroids and prolactin on phosphatases, transaminases, and citric acid in the ventral prostate of male albino rats.
Topics: Acid Phosphatase; Aging; Animals; Castration; Citrates; Citric Acid; DNA; Drug Synergism; Gonadal St | 1987 |
Taste intensity perception in aging.
Topics: Adult; Aged; Aging; Citrates; Citric Acid; Female; Humans; Male; Middle Aged; Quinine; Sodium Chlori | 1986 |
Effect of age on lung mechanics and airway reactivity in lambs.
Topics: Aging; Animals; Carbachol; Citrates; Citric Acid; Female; Histamine; Lung; Lung Volume Measurements; | 1986 |
The effect of age on glucose and energy metabolism in brain cortex of rats.
Topics: Adenosine Triphosphate; Aging; Animals; Cerebral Cortex; Citrates; Citric Acid; Energy Metabolism; G | 1985 |