Page last updated: 2024-10-25

citalopram and Stroke

citalopram has been researched along with Stroke in 66 studies

Citalopram: A furancarbonitrile that is one of the serotonin uptake inhibitors used as an antidepressant. The drug is also effective in reducing ethanol uptake in alcoholics and is used in depressed patients who also suffer from TARDIVE DYSKINESIA in preference to tricyclic antidepressants, which aggravate dyskinesia.
citalopram : A racemate comprising equimolar amounts of (R)-citalopram and its enantiomer, escitalopram. It is used as an antidepressant, although only escitalopram is active.
1-[3-(dimethylamino)propyl]-1-(4-fluorophenyl)-1,3-dihydro-2-benzofuran-5-carbonitrile : A nitrile that is 1,3-dihydro-2-benzofuran-5-carbonitrile in which one of the hydrogens at position 1 is replaced by a p-fluorophenyl group, while the other is replaced by a 3-(dimethylamino)propyl group.

Stroke: A group of pathological conditions characterized by sudden, non-convulsive loss of neurological function due to BRAIN ISCHEMIA or INTRACRANIAL HEMORRHAGES. Stroke is classified by the type of tissue NECROSIS, such as the anatomic location, vasculature involved, etiology, age of the affected individual, and hemorrhagic vs. non-hemorrhagic nature. (From Adams et al., Principles of Neurology, 6th ed, pp777-810)

Research Excerpts

ExcerptRelevanceReference
"4 %) received citalopram and median (IQR) prestroke PASE score was 132."9.69Impact of prestroke physical activity and citalopram treatment on poststroke depressive symptoms: a secondary analysis of data from the TALOS randomised controlled trial in Denmark. ( Andersen, G; Blauenfeldt, RA; Damsbo, AG; Johnsen, SP; Mortensen, JK; Vestergaard, SB, 2023)
"The effect of escitalopram on PSD may be more prominent in patients with particular depressive symptoms and stroke lesion locations, suggesting the need for tailored treatment strategies."9.41Post-Stroke Depressive Symptoms: Varying Responses to Escitalopram by Individual Symptoms and Lesion Location. ( Ahn, SH; Cha, JK; Chang, DI; Choi-Kwon, S; Heo, JH; Kim, DE; Kim, HY; Kim, J; Kim, JS; Kim, JY; Kim, MS; Kim, S; Koh, SH; Kwon, DY; Lee, BC; Lee, EJ; Lee, J; Lee, JS; Park, JH; Park, SW; Seo, WK; Sohn, SI, 2021)
"This study aimed to investigate whether the routine administration of escitalopram for three months would improve the prognosis of patients with ischemic stroke and decrease the plasma copeptin level."9.34Effects of the prophylactic use of escitalopram on the prognosis and the plasma copeptin level in patients with acute cerebral infarction. ( Cao, JX; Chen, JC; Liu, L; Sun, YT; Wang, Y; Zeng, QH, 2020)
"We evaluated the effect of SSRI treatment on platelet aggregation in patients with ischaemic stroke and included patients from the randomized double-blind controlled study of citalopram in acute ischaemic stroke (TALOS)."9.30Antiplatelet effects of citalopram in patients with ischaemic stroke: A randomized, placebo-controlled, double-blind study. ( Andersen, G; Grove, EL; Johnsen, SP; Kraglund, KL; Mortensen, JK, 2019)
"There was no significant difference between citalopram and fluoxetine in facilitating post-stroke motor recovery in ischemic stroke patients."9.27The efficacy comparison of citalopram, fluoxetine, and placebo on motor recovery after ischemic stroke: a double-blind placebo-controlled randomized controlled trial. ( Asadollahi, M; Karimialavijeh, E; Khanmoradi, Z; Ramezani, M, 2018)
"This study re-examined patients from a 1-year randomized controlled double-blind trial of escitalopram, problem-solving therapy (PST), or placebo to prevent depression among patients less than 3 months after a stroke."9.24Prevention of Poststroke Mortality Using Problem-Solving Therapy or Escitalopram. ( Jorge, RE; Long, J; Robinson, RG, 2017)
"Escitalopram did not significantly reduce moderate or severe depressive symptoms in patients with acute stroke."9.24Efficacy of early administration of escitalopram on depressive and emotional symptoms and neurological dysfunction after stroke: a multicentre, double-blind, randomised, placebo-controlled study. ( Ahn, SH; Cha, JK; Chang, DI; Choi-Kwon, S; Heo, JH; Kim, DE; Kim, HY; Kim, J; Kim, JS; Kim, JY; Kim, S; Koh, SH; Kwon, DY; Lee, BC; Lee, EJ; Lee, J; Park, JH; Park, SW; Seo, WK; Sohn, SI, 2017)
"TALOS is an investigator-initiated, national multicenter randomized- and placebo-controlled, double-blind trial testing citalopram in acute ischemic stroke."9.20TALOS: a multicenter, randomized, double-blind, placebo-controlled trial to test the effects of citalopram in patients with acute stroke. ( Andersen, G; Grove, EL; Johnsen, SP; Kraglund, KL; Mortensen, JK, 2015)
"Escitalopram or PST was significantly more effective in preventing new onset of apathy following stroke compared with placebo."9.17Prevention of poststroke apathy using escitalopram or problem-solving therapy. ( Arndt, S; Fonzetti, P; Hegel, MT; Jang, M; Jorge, RE; Mikami, K; Moser, DJ; Robinson, RG; Small, SL; Solodkin, A, 2013)
"The authors sought to determine the relative efficacy and tolerability of duloxetine versus citalopram and sertraline in the treatment of poststroke depression (PSD), anxiety, and fatigue."9.16Duloxetine versus citalopram and sertraline in the treatment of poststroke depression, anxiety, and fatigue. ( Karaiskos, D; Paparrigopoulos, T; Spengos, K; Tzavellas, E; Vassilopoulou, S, 2012)
"Discontinuation of escitalopram may increase poststroke depressive symptoms."9.15Increased frequency of first-episode poststroke depression after discontinuation of escitalopram. ( Arndt, S; Fonzetti, P; Hegel, MT; Jang, M; Jorge, RE; Mikami, K; Moser, DJ; Robinson, RG; Small, SL; Solodkin, A, 2011)
"When compared with patients who received placebo or underwent Problem Solving Therapy, stroke patients who received escitalopram showed improvement in global cognitive functioning, specifically in verbal and visual memory functions."9.14Escitalopram and enhancement of cognitive recovery following stroke. ( Acion, L; Adams, HP; Jorge, RE; Moser, D; Robinson, RG, 2010)
"Patients who received placebo were significantly more likely to develop depression than individuals who received escitalopram (11 major and 2 minor cases of depression [22."9.13Escitalopram and problem-solving therapy for prevention of poststroke depression: a randomized controlled trial. ( Acion, L; Arndt, S; Fonzetti, P; Hegel, M; Jorge, RE; Moser, DJ; Robinson, RG; Small, SL; Solodkin, A, 2008)
"The effect of a combination of light therapy and citalopram in stroke victims receiving citalopram was examined by use of two different doses of light therapy under double-blind conditions."9.12Dose response to adjunctive light therapy in citalopram-treated patients with post-stroke depression. A randomised, double-blind pilot study. ( Andersen, G; Bech, P; Jarden, JO; Martiny, K; Søndergaard, MP, 2006)
" Significant decreases on Hamilton Depression Scale scores were observed in favor of citalopram when compared to other SSRIs after 4-, 6-week treatment [SMD = -."8.98Efficacy and Safety of Citalopram for the Treatment of Poststroke Depression: A Meta-Analysis. ( Cui, M; Huang, CY; Wang, F, 2018)
"02), and the Hamilton Depression Scale with citalopram was lower than that found with other SSRIs (SMD -0."8.91Efficacy and Safety of Citalopram in Treating Post-Stroke Depression: A Meta-Analysis. ( Ding, L; Hong, H; Huang, X; Tan, S, 2015)
"This study aims to assess the efficacy and safety of citalopram for the treatment of patients with post-stroke depression (PSD)."7.96Does citalopram effectively treat post-stroke depression?: A protocol for systematic review and meta analysis. ( Hu, J; Ma, L; Yang, ZY, 2020)
"This retrospective study investigated the efficacy and safety of escitalopram oxalate (ESO) for the treatment of post-stroke depression (PSD)."7.88Efficacy of escitalopram oxalate for patients with post-stroke depression. ( Jiang, P; Xu, JH, 2018)
"gov NCT01278498), a randomised, placebo-controlled, double-blind trial examining the efficacy of escitalopram on emotional and neurological disturbances after acute stroke."7.88Serotonin transporter gene polymorphisms may be associated with poststroke neurological recovery after escitalopram use. ( Cha, JK; Chang, DI; Heo, JH; Kim, DE; Kim, HY; Kim, J; Kim, JS; Kim, YJ; Lee, BC; Lee, EJ; Lee, J; Oh, MS; Park, JH; Park, SW; Seo, WK; Sohn, SI, 2018)
"Citalopram is a safe and tolerable medication in patients with acute IS, which could improve the outcome in these patients."6.84Efficacy of Citalopram on Acute Ischemic Stroke Outcome: A Randomized Clinical Trial. ( Abbaszade, Z; Ghazanfari Amlashi, S; Golzari, SEJ; Hashemilar, M; Nikanfar, M; Rikhtegar, R; Sadeghi Bazargani, H; Sadeghihokmabadi, E; Savadi Oskouie, D; Sharifipour, E, 2017)
"Citalopram-treated animals (n = 13) showed a significant increase in impaired forepaw use in the staircase task compared with saline-treated animals (n = 12) 2, 3 and 7 weeks post stroke but no difference in neurological score at any time point examined."5.72Delayed citalopram administration reduces brain inflammation and enhances skilled motor function after ischaemic stroke in 'MacGreen' mice. ( Bennet, L; Chen, S; McGregor, AL, 2022)
"4 %) received citalopram and median (IQR) prestroke PASE score was 132."5.69Impact of prestroke physical activity and citalopram treatment on poststroke depressive symptoms: a secondary analysis of data from the TALOS randomised controlled trial in Denmark. ( Andersen, G; Blauenfeldt, RA; Damsbo, AG; Johnsen, SP; Mortensen, JK; Vestergaard, SB, 2023)
"The effect of escitalopram on PSD may be more prominent in patients with particular depressive symptoms and stroke lesion locations, suggesting the need for tailored treatment strategies."5.41Post-Stroke Depressive Symptoms: Varying Responses to Escitalopram by Individual Symptoms and Lesion Location. ( Ahn, SH; Cha, JK; Chang, DI; Choi-Kwon, S; Heo, JH; Kim, DE; Kim, HY; Kim, J; Kim, JS; Kim, JY; Kim, MS; Kim, S; Koh, SH; Kwon, DY; Lee, BC; Lee, EJ; Lee, J; Lee, JS; Park, JH; Park, SW; Seo, WK; Sohn, SI, 2021)
"Citalopram treatment had no significant effect on infarct formation or edema 3 days after stroke; however, citalopram-treated mice had better functional recovery than saline-treated controls 3 and 14 days after stroke in the adhesive removal test."5.39Citalopram enhances neurovascular regeneration and sensorimotor functional recovery after ischemic stroke in mice. ( Espinera, AR; Gu, X; Ogle, ME; Wei, L, 2013)
"gov, NCT01278498), a randomized, placebo-controlled, double-blind trial that examined the efficacy of escitalopram for 3 months on depression in patients with acute stroke."5.34Depressive Symptoms in Stroke Patients: Are There Sex Differences? ( Ahn, SH; Cha, JK; Chang, DI; Choi-Kwon, S; Heo, JH; Kim, DE; Kim, HY; Kim, J; Kim, JS; Kim, JY; Kim, S; Koh, SH; Kwon, DY; Lee, BC; Lee, EJ; Lee, J; Park, JH; Park, SW; Seo, WK; Sohn, SI, 2020)
"This study aimed to investigate whether the routine administration of escitalopram for three months would improve the prognosis of patients with ischemic stroke and decrease the plasma copeptin level."5.34Effects of the prophylactic use of escitalopram on the prognosis and the plasma copeptin level in patients with acute cerebral infarction. ( Cao, JX; Chen, JC; Liu, L; Sun, YT; Wang, Y; Zeng, QH, 2020)
"We evaluated the effect of SSRI treatment on platelet aggregation in patients with ischaemic stroke and included patients from the randomized double-blind controlled study of citalopram in acute ischaemic stroke (TALOS)."5.30Antiplatelet effects of citalopram in patients with ischaemic stroke: A randomized, placebo-controlled, double-blind study. ( Andersen, G; Grove, EL; Johnsen, SP; Kraglund, KL; Mortensen, JK, 2019)
"SERT gene polymorphisms in 270 non-depressed first-ever acute ischemic stroke patients randomized to citalopram, n = 130, or placebo, n = 140, were investigated."5.30Serotonergic Regulation and Cognition after Stroke: The Role of Antidepressant Treatment and Genetic Variation. ( Andersen, G; Buttenschøn, HN; Damsbo, AG; Johnsen, SP; Kraglund, KL; Mortensen, JK, 2019)
"There was no significant difference between citalopram and fluoxetine in facilitating post-stroke motor recovery in ischemic stroke patients."5.27The efficacy comparison of citalopram, fluoxetine, and placebo on motor recovery after ischemic stroke: a double-blind placebo-controlled randomized controlled trial. ( Asadollahi, M; Karimialavijeh, E; Khanmoradi, Z; Ramezani, M, 2018)
"Serving as a pilot study of poststroke pharmacotherapy, the present investigation was intended to establish the effect of a single dose of escitalopram on motor task performance in normal volunteers."5.27The effect of a single dose of escitalopram on sensorimotor networks. ( Eap, CB; Kägi, G; Krammer, W; Missimer, JH; Weder, BJ; Weisstanner, C; Wiest, R, 2018)
"This study re-examined patients from a 1-year randomized controlled double-blind trial of escitalopram, problem-solving therapy (PST), or placebo to prevent depression among patients less than 3 months after a stroke."5.24Prevention of Poststroke Mortality Using Problem-Solving Therapy or Escitalopram. ( Jorge, RE; Long, J; Robinson, RG, 2017)
"Escitalopram did not significantly reduce moderate or severe depressive symptoms in patients with acute stroke."5.24Efficacy of early administration of escitalopram on depressive and emotional symptoms and neurological dysfunction after stroke: a multicentre, double-blind, randomised, placebo-controlled study. ( Ahn, SH; Cha, JK; Chang, DI; Choi-Kwon, S; Heo, JH; Kim, DE; Kim, HY; Kim, J; Kim, JS; Kim, JY; Kim, S; Koh, SH; Kwon, DY; Lee, BC; Lee, EJ; Lee, J; Park, JH; Park, SW; Seo, WK; Sohn, SI, 2017)
"TALOS is an investigator-initiated, national multicenter randomized- and placebo-controlled, double-blind trial testing citalopram in acute ischemic stroke."5.20TALOS: a multicenter, randomized, double-blind, placebo-controlled trial to test the effects of citalopram in patients with acute stroke. ( Andersen, G; Grove, EL; Johnsen, SP; Kraglund, KL; Mortensen, JK, 2015)
"Escitalopram or PST was significantly more effective in preventing new onset of apathy following stroke compared with placebo."5.17Prevention of poststroke apathy using escitalopram or problem-solving therapy. ( Arndt, S; Fonzetti, P; Hegel, MT; Jang, M; Jorge, RE; Mikami, K; Moser, DJ; Robinson, RG; Small, SL; Solodkin, A, 2013)
"The authors sought to determine the relative efficacy and tolerability of duloxetine versus citalopram and sertraline in the treatment of poststroke depression (PSD), anxiety, and fatigue."5.16Duloxetine versus citalopram and sertraline in the treatment of poststroke depression, anxiety, and fatigue. ( Karaiskos, D; Paparrigopoulos, T; Spengos, K; Tzavellas, E; Vassilopoulou, S, 2012)
"Discontinuation of escitalopram may increase poststroke depressive symptoms."5.15Increased frequency of first-episode poststroke depression after discontinuation of escitalopram. ( Arndt, S; Fonzetti, P; Hegel, MT; Jang, M; Jorge, RE; Mikami, K; Moser, DJ; Robinson, RG; Small, SL; Solodkin, A, 2011)
"When compared with patients who received placebo or underwent Problem Solving Therapy, stroke patients who received escitalopram showed improvement in global cognitive functioning, specifically in verbal and visual memory functions."5.14Escitalopram and enhancement of cognitive recovery following stroke. ( Acion, L; Adams, HP; Jorge, RE; Moser, D; Robinson, RG, 2010)
"Patients who received placebo were significantly more likely to develop depression than individuals who received escitalopram (11 major and 2 minor cases of depression [22."5.13Escitalopram and problem-solving therapy for prevention of poststroke depression: a randomized controlled trial. ( Acion, L; Arndt, S; Fonzetti, P; Hegel, M; Jorge, RE; Moser, DJ; Robinson, RG; Small, SL; Solodkin, A, 2008)
"Based on available RCTs of fluoxetine and citalopram, SSRIs used for 6 months doubled the risk of fractures in stroke survivors."5.12Risk of Fractures in Stroke Patients Treated With a Selective Serotonin Reuptake Inhibitor: A Systematic Review and Meta-Analysis. ( Almeida, OP; Hankey, GJ; Jones, JS; Kimata, R, 2021)
"The effect of a combination of light therapy and citalopram in stroke victims receiving citalopram was examined by use of two different doses of light therapy under double-blind conditions."5.12Dose response to adjunctive light therapy in citalopram-treated patients with post-stroke depression. A randomised, double-blind pilot study. ( Andersen, G; Bech, P; Jarden, JO; Martiny, K; Søndergaard, MP, 2006)
"Escitalopram was associated with a quicker relief of depression, but mirtazapine was probably the best option when it comes to the efficacy of 8-week treatment duration."5.05Comparative efficacy of nine antidepressants in treating Chinese patients with post-stroke depression: A network meta-analysis. ( Li, X; Zhang, C, 2020)
" Significant decreases on Hamilton Depression Scale scores were observed in favor of citalopram when compared to other SSRIs after 4-, 6-week treatment [SMD = -."4.98Efficacy and Safety of Citalopram for the Treatment of Poststroke Depression: A Meta-Analysis. ( Cui, M; Huang, CY; Wang, F, 2018)
"02), and the Hamilton Depression Scale with citalopram was lower than that found with other SSRIs (SMD -0."4.91Efficacy and Safety of Citalopram in Treating Post-Stroke Depression: A Meta-Analysis. ( Ding, L; Hong, H; Huang, X; Tan, S, 2015)
"Randomized controlled trials have demonstrated the efficacy of sertraline, citalopram and nortriptyline to treat post-stroke depression."4.84Antidepressant therapy in post-stroke depression. ( Mizrahi, R; Power, BD; Starkstein, SE, 2008)
"This study aims to assess the efficacy and safety of citalopram for the treatment of patients with post-stroke depression (PSD)."3.96Does citalopram effectively treat post-stroke depression?: A protocol for systematic review and meta analysis. ( Hu, J; Ma, L; Yang, ZY, 2020)
"This retrospective study investigated the efficacy and safety of escitalopram oxalate (ESO) for the treatment of post-stroke depression (PSD)."3.88Efficacy of escitalopram oxalate for patients with post-stroke depression. ( Jiang, P; Xu, JH, 2018)
"gov NCT01278498), a randomised, placebo-controlled, double-blind trial examining the efficacy of escitalopram on emotional and neurological disturbances after acute stroke."3.88Serotonin transporter gene polymorphisms may be associated with poststroke neurological recovery after escitalopram use. ( Cha, JK; Chang, DI; Heo, JH; Kim, DE; Kim, HY; Kim, J; Kim, JS; Kim, YJ; Lee, BC; Lee, EJ; Lee, J; Oh, MS; Park, JH; Park, SW; Seo, WK; Sohn, SI, 2018)
"Depression is a common complication after stroke and is closely related to the poor prognosis of stroke."3.01Clinical efficacy of Danzhi Xiaoyao Powder in the treatment of post-stroke depression: A protocol for randomized, double-blind clinical study. ( Ding, C; Gao, L; Guo, M; Wang, X; Xu, M; Xu, W; Yao, J, 2021)
"Citalopram is a safe and tolerable medication in patients with acute IS, which could improve the outcome in these patients."2.84Efficacy of Citalopram on Acute Ischemic Stroke Outcome: A Randomized Clinical Trial. ( Abbaszade, Z; Ghazanfari Amlashi, S; Golzari, SEJ; Hashemilar, M; Nikanfar, M; Rikhtegar, R; Sadeghi Bazargani, H; Sadeghihokmabadi, E; Savadi Oskouie, D; Sharifipour, E, 2017)
" A selective serotonergic drug (citalopram) or a placebo was administered using a mean dosage of 10 mg/day in combination with physiotherapy."2.74A double blind placebo RCT to investigate the effects of serotonergic modulation on brain excitability and motor recovery in stroke patients. ( Acler, M; Fiaschi, A; Manganotti, P; Robol, E, 2009)
"Stroke is the major cause of adult disability."2.48Selective serotonin reuptake inhibitors (SSRIs) for stroke recovery. ( Claxton, A; Hackett, ML; Hankey, GJ; Hsieh, CF; Kutlubaev, MA; Lee, R; Mead, GE, 2012)
"Citalopram-treated animals (n = 13) showed a significant increase in impaired forepaw use in the staircase task compared with saline-treated animals (n = 12) 2, 3 and 7 weeks post stroke but no difference in neurological score at any time point examined."1.72Delayed citalopram administration reduces brain inflammation and enhances skilled motor function after ischaemic stroke in 'MacGreen' mice. ( Bennet, L; Chen, S; McGregor, AL, 2022)
"Citalopram treatment had no significant effect on infarct formation or edema 3 days after stroke; however, citalopram-treated mice had better functional recovery than saline-treated controls 3 and 14 days after stroke in the adhesive removal test."1.39Citalopram enhances neurovascular regeneration and sensorimotor functional recovery after ischemic stroke in mice. ( Espinera, AR; Gu, X; Ogle, ME; Wei, L, 2013)
"Early diagnosis and effective treatment of depression will help the rehabilitation outcome of stroke patients."1.35Depression and functional outcome after stroke: the effect of antidepressant therapy on functional recovery. ( Bilge, C; Koçer, A; Koçer, E; Türk Börü, U, 2008)
" CMS induced behavioural changes in the ischemic animals, including decreased locomotor and rearing activity and reduced sucrose preference (compared with baseline, control and stroke groups respectively), all these behaviours were reversed by chronic administration of citalopram."1.35Anhedonia and activity deficits in rats: impact of post-stroke depression. ( Chen, BA; Guo, YJ; Teng, GJ; Wang, SH; Zhang, ZJ; Zhou, H, 2009)

Research

Studies (66)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's22 (33.33)29.6817
2010's32 (48.48)24.3611
2020's12 (18.18)2.80

Authors

AuthorsStudies
Ding, C1
Xu, M1
Gao, L1
Wang, X1
Xu, W1
Guo, M1
Yao, J1
Chen, S1
Bennet, L1
McGregor, AL1
Ece Çetin, F1
Kumral, E1
Saffet Gönül, A1
Nezih Özdemir, H1
Orman, M1
Kalbouneh, HM1
Toubasi, AA1
Albustanji, FH1
Obaid, YY1
Al-Harasis, LM1
Taghizadeh-Ghehi, M1
Emami, M1
Heidari, K1
Vestergaard, SB1
Damsbo, AG3
Blauenfeldt, RA1
Johnsen, SP5
Andersen, G7
Mortensen, JK5
Kraglund, KL4
Grove, EL3
Lee, EJ4
Kim, JS4
Chang, DI4
Park, JH4
Ahn, SH3
Cha, JK4
Heo, JH4
Sohn, SI4
Lee, BC4
Kim, DE4
Kim, HY4
Kim, S3
Kwon, DY3
Kim, J5
Seo, WK4
Lee, J4
Park, SW4
Koh, SH3
Kim, JY3
Choi-Kwon, S3
Li, X1
Zhang, C1
Hu, J1
Ma, L1
Yang, ZY1
Kim, MS1
Lee, JS1
Cao, JX1
Liu, L1
Sun, YT1
Zeng, QH1
Wang, Y1
Chen, JC1
Jones, JS1
Kimata, R1
Almeida, OP1
Hankey, GJ2
Savadi Oskouie, D1
Sharifipour, E1
Sadeghi Bazargani, H1
Hashemilar, M1
Nikanfar, M1
Ghazanfari Amlashi, S1
Abbaszade, Z1
Sadeghihokmabadi, E1
Rikhtegar, R1
Golzari, SEJ1
Sun, Y1
Liang, Y1
Jiao, Y1
Lin, J1
Qu, H1
Xu, J1
Zhao, C1
Oh, MS1
Kim, YJ1
Xu, JH1
Jiang, P1
Gupta, S1
Upadhayay, D1
Sharma, U1
Jagannathan, NR1
Gupta, YK1
Asadollahi, M1
Ramezani, M1
Khanmoradi, Z1
Karimialavijeh, E1
Kim, Y1
Weisstanner, C1
Kägi, G1
Krammer, W1
Eap, CB1
Wiest, R1
Missimer, JH1
Weder, BJ1
Cui, M1
Huang, CY1
Wang, F1
Modrau, B1
Simonsen, SA1
Iversen, HK1
Madsen, M1
Buttenschøn, HN1
Espinera, AR1
Ogle, ME1
Gu, X1
Wei, L1
Madani, Y1
Azad, S1
Nachev, P1
Collas, D1
Mikami, K3
Jorge, RE6
Moser, DJ4
Arndt, S5
Jang, M3
Solodkin, A4
Small, SL4
Fonzetti, P4
Hegel, MT3
Robinson, RG7
Wang, SS1
Wang, YG1
Chen, HY1
Wu, ZP1
Xie, HG1
Affan, M1
Shaikh, Q1
Kamal, AK1
Lin, DH1
Zhang, XR1
Ye, DQ1
Xi, GJ1
Hui, JJ1
Liu, SS1
Li, LJ1
Zhang, ZJ3
Tan, S1
Huang, X1
Ding, L1
Hong, H1
Gao, J1
Lin, M1
Zhao, J1
Bi, S1
Ni, Z1
Shang, X1
Kumar, S1
Long, J1
Wang, SH2
Guo, YJ2
Zhou, H1
Teng, GJ2
Chen, BA2
Lacasse, J1
Leo, J1
Dettling, M1
Opgen-Rhein, C1
Anghelescu, I1
Schulte-Herbrüggen, O1
Röpke, S1
Rasmussen, A1
Hanash, JA1
Bech, P2
Tallelli, P1
Werring, DJ1
Acler, M1
Robol, E1
Fiaschi, A1
Manganotti, P1
Gusev, EI2
Bogolepova, AN2
Acion, L2
Moser, D1
Adams, HP1
Aggarwal, A2
Kumar, R2
Sharma, RC1
Sharma, DD2
Sharma, R1
Kronenberg, G1
Balkaya, M1
Prinz, V1
Gertz, K1
Ji, S1
Kirste, I1
Heuser, I1
Kampmann, B1
Hellmann-Regen, J1
Gass, P1
Sohr, R1
Hellweg, R1
Waeber, C1
Juckel, G1
Hörtnagl, H1
Stumm, R1
Endres, M1
Karaiskos, D1
Tzavellas, E1
Spengos, K1
Vassilopoulou, S1
Paparrigopoulos, T1
Mead, GE1
Hsieh, CF1
Lee, R1
Kutlubaev, MA1
Claxton, A1
Hackett, ML1
Rampello, L1
Chiechio, S1
Nicoletti, G1
Alvano, A1
Vecchio, I1
Raffaele, R1
Malaguarnera, M1
Søndergaard, MP1
Jarden, JO1
Martiny, K1
Simis, S1
Nitrini, R1
Beyenburg, S1
Schönegger, K1
Møller, M1
Gjedde, A1
Giacobbe, P1
Flint, A1
Bilge, C1
Koçer, E1
Koçer, A1
Türk Börü, U1
Starkstein, SE1
Mizrahi, R1
Power, BD1
Hegel, M1
Hagebeuk, EE1
Tans, JT1
de Regt, EW1

Clinical Trials (9)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
A Multicenter, Double Blind Trial to Compare the Efficacy and Safety of Escitalopram With Placebo in Patients With Acute Stroke for the Prevention of Poststroke Depression and Related Symptoms (Emotional Incontinence, Anger Proneness), and for Improvement[NCT01278498]Phase 4444 participants (Anticipated)Interventional2011-01-31Active, not recruiting
Clinical Study Evaluating the Efficacy of Nitazoxanide and Escitalopram as Adjuvant Therapies in Patients With Rheumatoid Arthritis[NCT05480878]Phase 390 participants (Actual)Interventional2022-12-02Completed
The Efficacy of Citalopram Treatment in Acute Stroke[NCT01937182]Phase 2642 participants (Actual)Interventional2013-09-30Completed
Escitalopram and Language Intervention for Subacute Aphasia (ELISA)[NCT03843463]Phase 288 participants (Anticipated)Interventional2021-07-18Recruiting
FLOW Trial: Fluoxetine to Open the Critical Period Time Window to Improve Motor Recovery After Stroke[NCT03448159]Phase 252 participants (Actual)Interventional2019-01-01Completed
A Multicenter, Randomized, Double-blind, Placebo-controlled Study Evaluating the Efficacy and Safety of Agomelatine in the Prevention of Poststroke Depression[NCT05426304]Phase 4420 participants (Anticipated)Interventional2022-10-01Not yet recruiting
Prevention of Post-Stroke Depression - Treatment Strategy[NCT00071643]201 participants (Actual)Interventional2002-09-30Completed
Establishing the Effect(s) and Safety of Fluoxetine Initiated in the Acute Phase of Stroke[NCT02683213]Phase 31,500 participants (Actual)Interventional2014-10-20Completed
Effect of Serotonin and Levodopa Functional Recovery in Patients With Cerebral Infarction[NCT02386475]Phase 439 participants (Actual)Interventional2015-01-31Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

7 reviews available for citalopram and Stroke

ArticleYear
Safety and Efficacy of SSRIs in Improving Poststroke Recovery: A Systematic Review and Meta-Analysis.
    Journal of the American Heart Association, 2022, 07-05, Volume: 11, Issue:13

    Topics: Anxiety; Citalopram; Fluoxetine; Humans; Selective Serotonin Reuptake Inhibitors; Stroke; United Sta

2022
Comparative efficacy of nine antidepressants in treating Chinese patients with post-stroke depression: A network meta-analysis.
    Journal of affective disorders, 2020, 04-01, Volume: 266

    Topics: Antidepressive Agents; China; Citalopram; Depression; Depressive Disorder, Major; Humans; Network Me

2020
Risk of Fractures in Stroke Patients Treated With a Selective Serotonin Reuptake Inhibitor: A Systematic Review and Meta-Analysis.
    Stroke, 2021, Volume: 52, Issue:9

    Topics: Citalopram; Depression; Fluoxetine; Fractures, Bone; Humans; Selective Serotonin Reuptake Inhibitors

2021
Efficacy and Safety of Citalopram for the Treatment of Poststroke Depression: A Meta-Analysis.
    Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association, 2018, Volume: 27, Issue:11

    Topics: Antidepressive Agents, Second-Generation; Chi-Square Distribution; Citalopram; Depression; Humans; O

2018
Efficacy and Safety of Citalopram in Treating Post-Stroke Depression: A Meta-Analysis.
    European neurology, 2015, Volume: 74, Issue:3-4

    Topics: Citalopram; Depression; Humans; Psychiatric Status Rating Scales; Selective Serotonin Reuptake Inhib

2015
Selective serotonin reuptake inhibitors (SSRIs) for stroke recovery.
    The Cochrane database of systematic reviews, 2012, Nov-14, Volume: 11

    Topics: Adult; Anxiety; Citalopram; Cognition; Depression; Fluoxetine; Humans; Nervous System Diseases; Paro

2012
Selective serotonin reuptake inhibitors (SSRIs) for stroke recovery.
    The Cochrane database of systematic reviews, 2012, Nov-14, Volume: 11

    Topics: Adult; Anxiety; Citalopram; Cognition; Depression; Fluoxetine; Humans; Nervous System Diseases; Paro

2012
Selective serotonin reuptake inhibitors (SSRIs) for stroke recovery.
    The Cochrane database of systematic reviews, 2012, Nov-14, Volume: 11

    Topics: Adult; Anxiety; Citalopram; Cognition; Depression; Fluoxetine; Humans; Nervous System Diseases; Paro

2012
Selective serotonin reuptake inhibitors (SSRIs) for stroke recovery.
    The Cochrane database of systematic reviews, 2012, Nov-14, Volume: 11

    Topics: Adult; Anxiety; Citalopram; Cognition; Depression; Fluoxetine; Humans; Nervous System Diseases; Paro

2012
Antidepressant therapy in post-stroke depression.
    Expert opinion on pharmacotherapy, 2008, Volume: 9, Issue:8

    Topics: Antidepressive Agents; Citalopram; Controlled Clinical Trials as Topic; Depressive Disorder; Humans;

2008

Trials

28 trials available for citalopram and Stroke

ArticleYear
Clinical efficacy of Danzhi Xiaoyao Powder in the treatment of post-stroke depression: A protocol for randomized, double-blind clinical study.
    Medicine, 2021, Oct-22, Volume: 100, Issue:42

    Topics: Adolescent; Adult; Aged; Antidepressive Agents; Citalopram; Depression; Double-Blind Method; Drug Th

2021
Effıcacy of cıtalopram on stroke recurrence: A randomızed clınıcal trıal.
    Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia, 2022, Volume: 101

    Topics: Citalopram; Double-Blind Method; Humans; Selective Serotonin Reuptake Inhibitors; Stroke; Treatment

2022
Impact of prestroke physical activity and citalopram treatment on poststroke depressive symptoms: a secondary analysis of data from the TALOS randomised controlled trial in Denmark.
    BMJ open, 2023, 03-30, Volume: 13, Issue:3

    Topics: Aged; Brain Ischemia; Citalopram; Denmark; Depression; Exercise; Female; Humans; Ischemic Stroke; Ma

2023
Antiplatelet effects of citalopram in patients with ischaemic stroke: A randomized, placebo-controlled, double-blind study.
    Scientific reports, 2019, 12-27, Volume: 9, Issue:1

    Topics: Aged; Aged, 80 and over; Brain Ischemia; Citalopram; Double-Blind Method; Female; Humans; Male; Midd

2019
Depressive Symptoms in Stroke Patients: Are There Sex Differences?
    Cerebrovascular diseases (Basel, Switzerland), 2020, Volume: 49, Issue:1

    Topics: Affect; Aged; Aged, 80 and over; Antidepressive Agents, Second-Generation; Citalopram; Depression; D

2020
Post-Stroke Depressive Symptoms: Varying Responses to Escitalopram by Individual Symptoms and Lesion Location.
    Journal of geriatric psychiatry and neurology, 2021, Volume: 34, Issue:6

    Topics: Citalopram; Depression; Depressive Disorder, Major; Double-Blind Method; Escitalopram; Humans; Selec

2021
Effects of the prophylactic use of escitalopram on the prognosis and the plasma copeptin level in patients with acute cerebral infarction.
    Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas, 2020, Volume: 53, Issue:11

    Topics: Acute Disease; Brain Ischemia; Cerebral Infarction; Citalopram; Humans; Stroke; United States

2020
Efficacy of Citalopram on Acute Ischemic Stroke Outcome: A Randomized Clinical Trial.
    Neurorehabilitation and neural repair, 2017, Volume: 31, Issue:7

    Topics: Adult; Aged; Aged, 80 and over; Brain Ischemia; Citalopram; Double-Blind Method; Female; Follow-Up S

2017
The efficacy comparison of citalopram, fluoxetine, and placebo on motor recovery after ischemic stroke: a double-blind placebo-controlled randomized controlled trial.
    Clinical rehabilitation, 2018, Volume: 32, Issue:8

    Topics: Citalopram; Disability Evaluation; Double-Blind Method; Female; Fluoxetine; Humans; Male; Middle Age

2018
The effect of a single dose of escitalopram on sensorimotor networks.
    Brain and behavior, 2018, Volume: 8, Issue:6

    Topics: Citalopram; Dose-Response Relationship, Drug; Double-Blind Method; Female; Healthy Volunteers; Human

2018
Neuroregeneration and Vascular Protection by Citalopram in Acute Ischemic Stroke (TALOS).
    Stroke, 2018, Volume: 49, Issue:11

    Topics: Adult; Aged; Aged, 80 and over; Brain Ischemia; Citalopram; Denmark; Double-Blind Method; Early Medi

2018
Neuroregeneration and Vascular Protection by Citalopram in Acute Ischemic Stroke (TALOS).
    Stroke, 2018, Volume: 49, Issue:11

    Topics: Adult; Aged; Aged, 80 and over; Brain Ischemia; Citalopram; Denmark; Double-Blind Method; Early Medi

2018
Neuroregeneration and Vascular Protection by Citalopram in Acute Ischemic Stroke (TALOS).
    Stroke, 2018, Volume: 49, Issue:11

    Topics: Adult; Aged; Aged, 80 and over; Brain Ischemia; Citalopram; Denmark; Double-Blind Method; Early Medi

2018
Neuroregeneration and Vascular Protection by Citalopram in Acute Ischemic Stroke (TALOS).
    Stroke, 2018, Volume: 49, Issue:11

    Topics: Adult; Aged; Aged, 80 and over; Brain Ischemia; Citalopram; Denmark; Double-Blind Method; Early Medi

2018
Serotonergic Regulation and Cognition after Stroke: The Role of Antidepressant Treatment and Genetic Variation.
    Cerebrovascular diseases (Basel, Switzerland), 2019, Volume: 47, Issue:1-2

    Topics: Aged; Antidepressive Agents, Second-Generation; Citalopram; Cognition; Cognition Disorders; Denmark;

2019
Prevention of poststroke apathy using escitalopram or problem-solving therapy.
    The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry, 2013, Volume: 21, Issue:9

    Topics: Aged; Antidepressive Agents, Second-Generation; Apathy; Citalopram; Female; Humans; Male; Mental Dis

2013
Prevention of post-stroke generalized anxiety disorder, using escitalopram or problem-solving therapy.
    The Journal of neuropsychiatry and clinical neurosciences, 2014,Fall, Volume: 26, Issue:4

    Topics: Adult; Aged; Antidepressive Agents, Second-Generation; Anxiety Disorders; Citalopram; Cognitive Beha

2014
TALOS: a multicenter, randomized, double-blind, placebo-controlled trial to test the effects of citalopram in patients with acute stroke.
    International journal of stroke : official journal of the International Stroke Society, 2015, Volume: 10, Issue:6

    Topics: Brain Ischemia; Citalopram; Double-Blind Method; Follow-Up Studies; Humans; Mental Status Schedule;

2015
Different interventions for post-ischaemic stroke depression in different time periods: a single-blind randomized controlled trial with stratification by time after stroke.
    Clinical rehabilitation, 2017, Volume: 31, Issue:1

    Topics: Aged; Antidepressive Agents, Second-Generation; Brain Ischemia; Citalopram; Depressive Disorder; Fem

2017
Efficacy of early administration of escitalopram on depressive and emotional symptoms and neurological dysfunction after stroke: a multicentre, double-blind, randomised, placebo-controlled study.
    The lancet. Psychiatry, 2017, Volume: 4, Issue:1

    Topics: Aged; Antidepressive Agents, Second-Generation; Citalopram; Depression; Double-Blind Method; Drug Ad

2017
Efficacy of early administration of escitalopram on depressive and emotional symptoms and neurological dysfunction after stroke: a multicentre, double-blind, randomised, placebo-controlled study.
    The lancet. Psychiatry, 2017, Volume: 4, Issue:1

    Topics: Aged; Antidepressive Agents, Second-Generation; Citalopram; Depression; Double-Blind Method; Drug Ad

2017
Efficacy of early administration of escitalopram on depressive and emotional symptoms and neurological dysfunction after stroke: a multicentre, double-blind, randomised, placebo-controlled study.
    The lancet. Psychiatry, 2017, Volume: 4, Issue:1

    Topics: Aged; Antidepressive Agents, Second-Generation; Citalopram; Depression; Double-Blind Method; Drug Ad

2017
Efficacy of early administration of escitalopram on depressive and emotional symptoms and neurological dysfunction after stroke: a multicentre, double-blind, randomised, placebo-controlled study.
    The lancet. Psychiatry, 2017, Volume: 4, Issue:1

    Topics: Aged; Antidepressive Agents, Second-Generation; Citalopram; Depression; Double-Blind Method; Drug Ad

2017
Prevention of Poststroke Mortality Using Problem-Solving Therapy or Escitalopram.
    The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry, 2017, Volume: 25, Issue:5

    Topics: Aged; Antidepressive Agents, Second-Generation; Citalopram; Depression; Double-Blind Method; Female;

2017
A double blind placebo RCT to investigate the effects of serotonergic modulation on brain excitability and motor recovery in stroke patients.
    Journal of neurology, 2009, Volume: 256, Issue:7

    Topics: Administration, Oral; Aged; Brain; Citalopram; Dominance, Cerebral; Double-Blind Method; Evoked Pote

2009
[Depressive disorders in patients after stroke].
    Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova, 2008, Volume: Suppl 22

    Topics: Adult; Aged; Aged, 80 and over; Anti-Anxiety Agents; Antidepressive Agents; Citalopram; Depressive D

2008
Depressive disorders in stroke patients.
    Neuroscience and behavioral physiology, 2009, Volume: 39, Issue:7

    Topics: Adult; Aged; Aged, 80 and over; Anti-Anxiety Agents; Antidepressive Agents; Citalopram; Depressive D

2009
Escitalopram and enhancement of cognitive recovery following stroke.
    Archives of general psychiatry, 2010, Volume: 67, Issue:2

    Topics: Aged; Citalopram; Cognition Disorders; Female; Humans; Male; Neuropsychological Tests; Problem Solvi

2010
Escitalopram and enhancement of cognitive recovery following stroke.
    Archives of general psychiatry, 2010, Volume: 67, Issue:2

    Topics: Aged; Citalopram; Cognition Disorders; Female; Humans; Male; Neuropsychological Tests; Problem Solvi

2010
Escitalopram and enhancement of cognitive recovery following stroke.
    Archives of general psychiatry, 2010, Volume: 67, Issue:2

    Topics: Aged; Citalopram; Cognition Disorders; Female; Humans; Male; Neuropsychological Tests; Problem Solvi

2010
Escitalopram and enhancement of cognitive recovery following stroke.
    Archives of general psychiatry, 2010, Volume: 67, Issue:2

    Topics: Aged; Citalopram; Cognition Disorders; Female; Humans; Male; Neuropsychological Tests; Problem Solvi

2010
Increased frequency of first-episode poststroke depression after discontinuation of escitalopram.
    Stroke, 2011, Volume: 42, Issue:11

    Topics: Aged; Aged, 80 and over; Citalopram; Depressive Disorder, Major; Double-Blind Method; Female; Humans

2011
Duloxetine versus citalopram and sertraline in the treatment of poststroke depression, anxiety, and fatigue.
    The Journal of neuropsychiatry and clinical neurosciences, 2012,Summer, Volume: 24, Issue:3

    Topics: Activities of Daily Living; Adult; Aged; Antidepressive Agents; Anxiety; Citalopram; Depression; Dul

2012
Prediction of the response to citalopram and reboxetine in post-stroke depressed patients.
    Psychopharmacology, 2004, Volume: 173, Issue:1-2

    Topics: Adrenergic Uptake Inhibitors; Aged; Analysis of Variance; Case-Control Studies; Citalopram; Depressi

2004
Dose response to adjunctive light therapy in citalopram-treated patients with post-stroke depression. A randomised, double-blind pilot study.
    Psychotherapy and psychosomatics, 2006, Volume: 75, Issue:4

    Topics: Aged; Citalopram; Combined Modality Therapy; Depressive Disorder, Major; Dose-Response Relationship,

2006
Serotonin 5HT1A receptor availability and pathological crying after stroke.
    Acta neurologica Scandinavica, 2007, Volume: 116, Issue:2

    Topics: Aged; Binding, Competitive; Brain; Citalopram; Crying; Depressive Disorder; Down-Regulation; Female;

2007
Escitalopram and problem-solving therapy for prevention of poststroke depression: a randomized controlled trial.
    JAMA, 2008, May-28, Volume: 299, Issue:20

    Topics: Aged; Citalopram; Depression; Depressive Disorder; Diagnostic and Statistical Manual of Mental Disor

2008
Escitalopram and problem-solving therapy for prevention of poststroke depression: a randomized controlled trial.
    JAMA, 2008, May-28, Volume: 299, Issue:20

    Topics: Aged; Citalopram; Depression; Depressive Disorder; Diagnostic and Statistical Manual of Mental Disor

2008
Escitalopram and problem-solving therapy for prevention of poststroke depression: a randomized controlled trial.
    JAMA, 2008, May-28, Volume: 299, Issue:20

    Topics: Aged; Citalopram; Depression; Depressive Disorder; Diagnostic and Statistical Manual of Mental Disor

2008
Escitalopram and problem-solving therapy for prevention of poststroke depression: a randomized controlled trial.
    JAMA, 2008, May-28, Volume: 299, Issue:20

    Topics: Aged; Citalopram; Depression; Depressive Disorder; Diagnostic and Statistical Manual of Mental Disor

2008

Other Studies

31 other studies available for citalopram and Stroke

ArticleYear
Delayed citalopram administration reduces brain inflammation and enhances skilled motor function after ischaemic stroke in 'MacGreen' mice.
    The European journal of neuroscience, 2022, Volume: 55, Issue:5

    Topics: Animals; Brain Ischemia; Citalopram; Disease Models, Animal; Encephalitis; Ischemic Stroke; Mice; Ne

2022
A recent clinical trial on efficacy of citalopram to prevent stroke recurrence: unresolved controversies.
    Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia, 2023, Volume: 113

    Topics: Citalopram; Double-Blind Method; Humans; Selective Serotonin Reuptake Inhibitors; Stroke; Treatment

2023
Does citalopram effectively treat post-stroke depression?: A protocol for systematic review and meta analysis.
    Medicine, 2020, Jun-26, Volume: 99, Issue:26

    Topics: Antidepressive Agents, Second-Generation; Citalopram; Depression; Humans; Meta-Analysis as Topic; Re

2020
Comparative efficacy and acceptability of antidepressant treatment in poststroke depression: a multiple-treatments meta-analysis.
    BMJ open, 2017, Aug-03, Volume: 7, Issue:8

    Topics: Aged; Antidepressive Agents; Antidepressive Agents, Second-Generation; Citalopram; Depression; Depre

2017
Serotonin transporter gene polymorphisms may be associated with poststroke neurological recovery after escitalopram use.
    Journal of neurology, neurosurgery, and psychiatry, 2018, Volume: 89, Issue:3

    Topics: Aged; Citalopram; Female; Genotype; Humans; Male; Middle Aged; Pharmacogenomic Variants; Polymorphis

2018
Efficacy of escitalopram oxalate for patients with post-stroke depression.
    Medicine, 2018, Volume: 97, Issue:14

    Topics: Acupressure; Aged; Antidepressive Agents, Second-Generation; Citalopram; Depression; Female; Humans;

2018
Citalopram attenuated neurobehavioral, biochemical, and metabolic alterations in transient middle cerebral artery occlusion model of stroke in male Wistar rats.
    Journal of neuroscience research, 2018, Volume: 96, Issue:7

    Topics: Animals; Brain; Brain Ischemia; Citalopram; Glutathione; Infarction, Middle Cerebral Artery; Male; M

2018
Which Patients Are Prescribed Escitalopram?: Predictors for Escitalopram Prescriptions and Functional Outcomes among Patients with Acute Ischemic Stroke.
    International journal of environmental research and public health, 2018, 05-28, Volume: 15, Issue:6

    Topics: Aged; Antidepressive Agents, Second-Generation; Citalopram; Depression; Female; Humans; Logistic Mod

2018
Citalopram enhances neurovascular regeneration and sensorimotor functional recovery after ischemic stroke in mice.
    Neuroscience, 2013, Sep-05, Volume: 247

    Topics: Animals; Brain Ischemia; Citalopram; Doublecortin Protein; Male; Mice; Mice, Inbred C57BL; Nerve Reg

2013
Laughing at funerals.
    QJM : monthly journal of the Association of Physicians, 2013, Volume: 106, Issue:10

    Topics: Brain Injuries; Citalopram; Humans; Laughter; Male; Middle Aged; Selective Serotonin Reuptake Inhibi

2013
Expression of genes encoding cytokines and corticotropin releasing factor are altered by citalopram in the hypothalamus of post-stroke depression rats.
    Neuro endocrinology letters, 2013, Volume: 34, Issue:8

    Topics: Animals; Antidepressive Agents, Second-Generation; Citalopram; Corticotropin-Releasing Hormone; Cyto

2013
Should I prevent my patient from developing depression after stroke? What is the best available option?
    JPMA. The Journal of the Pakistan Medical Association, 2014, Volume: 64, Issue:5

    Topics: Antidepressive Agents, Second-Generation; Citalopram; Depression; Humans; Stroke

2014
The Role of the Two-Pore Domain Potassium Channel TREK-1 in the Therapeutic Effects of Escitalopram in a Rat Model of Poststroke Depression.
    CNS neuroscience & therapeutics, 2015, Volume: 21, Issue:6

    Topics: Animals; Body Weight; Brain; Cell Proliferation; Citalopram; Depression; Disease Models, Animal; Exp

2015
Sobering news about post-stroke depression.
    The lancet. Psychiatry, 2017, Volume: 4, Issue:1

    Topics: Citalopram; Depression; Depressive Disorder; Double-Blind Method; Humans; Stroke

2017
Anhedonia and activity deficits in rats: impact of post-stroke depression.
    Journal of psychopharmacology (Oxford, England), 2009, Volume: 23, Issue:3

    Topics: Animals; Antidepressive Agents, Second-Generation; Behavior, Animal; Citalopram; Depression; Disease

2009
Escitalopram, problem-solving therapy, and poststroke depression.
    JAMA, 2008, Oct-15, Volume: 300, Issue:15

    Topics: Citalopram; Depression; Depressive Disorder; Humans; Problem Solving; Psychotherapy; Selective Serot

2008
Escitalopram, problem-solving therapy, and poststroke depression.
    JAMA, 2008, Oct-15, Volume: 300, Issue:15

    Topics: Citalopram; Depression; Depressive Disorder; Humans; Problem Solving; Psychotherapy; Selective Serot

2008
Escitalopram, problem-solving therapy, and poststroke depression.
    JAMA, 2008, Oct-15, Volume: 300, Issue:15

    Topics: Citalopram; Depression; Depressive Disorder; Humans; Problem Solving; Psychotherapy; Selective Serot

2008
Escitalopram, problem-solving therapy, and poststroke depression.
    JAMA, 2008, Oct-15, Volume: 300, Issue:15

    Topics: Citalopram; Depression; Depressive Disorder; Humans; Problem Solving; Psychotherapy; Selective Serot

2008
Medication and talk therapy help prevent depression after a stroke. Antidepressants and problem-solving therapy can prevent or delay the onset of post-stroke depression.
    DukeMedicine healthnews, 2008, Volume: 14, Issue:8

    Topics: Aged; Antidepressive Agents, Second-Generation; Citalopram; Clinical Trials as Topic; Depression; Hu

2008
Pharmacological augmentation of motor recovery after stroke: antidepressants for non-depressed patients?
    Journal of neurology, 2009, Volume: 256, Issue:7

    Topics: Antidepressive Agents, Second-Generation; Citalopram; Clinical Trials as Topic; Depressive Disorder;

2009
Incomplete financial disclosure in a study of escitalopram and problem-solving therapy for prevention of poststroke depression.
    JAMA, 2009, Mar-11, Volume: 301, Issue:10

    Topics: Citalopram; Depressive Disorder; Disclosure; Humans; Psychotherapy; Selective Serotonin Reuptake Inh

2009
Decreased expression of serotonin 1A receptor in the dentate gyrus in association with chronic mild stress: a rat model of post-stroke depression.
    Psychiatry research, 2009, Dec-30, Volume: 170, Issue:2-3

    Topics: Animals; Citalopram; Dentate Gyrus; Depression; Disease Models, Animal; Down-Regulation; Exploratory

2009
Escitalopram and ischemic stroke: cause or chance association?
    The Annals of pharmacotherapy, 2010, Volume: 44, Issue:9

    Topics: Adult; Citalopram; Depression; Humans; Male; Selective Serotonin Reuptake Inhibitors; Stroke

2010
Escitalopram and ischemic stroke: causal or chance association?
    The Journal of neuropsychiatry and clinical neurosciences, 2011,Spring, Volume: 23, Issue:2

    Topics: Adult; Antidepressive Agents; Brain Ischemia; Citalopram; Depressive Disorder; Humans; Male; Stroke

2011
Exofocal dopaminergic degeneration as antidepressant target in mouse model of poststroke depression.
    Biological psychiatry, 2012, Aug-15, Volume: 72, Issue:4

    Topics: Animals; Brain-Derived Neurotrophic Factor; Citalopram; Corticosterone; Depression; Disease Models,

2012
Cognitive improvement after treatment of depressive symptoms in the acute phase of stroke.
    Arquivos de neuro-psiquiatria, 2006, Volume: 64, Issue:2B

    Topics: Acute Disease; Adult; Aged; Aged, 80 and over; Antidepressive Agents, Second-Generation; Citalopram;

2006
Severe bradycardia in a stroke patient caused by a single low dose of escitalopram.
    European neurology, 2007, Volume: 57, Issue:1

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Anti-Ulcer Agents; Antidepressive Agents, Second-Generation

2007
Pharmacological treatment of post-stroke pathological laughing and crying.
    Journal of psychiatry & neuroscience : JPN, 2007, Volume: 32, Issue:5

    Topics: Antidepressive Agents; Citalopram; Crying; Humans; Laughter; Male; Mental Disorders; Middle Aged; Se

2007
Depression and functional outcome after stroke: the effect of antidepressant therapy on functional recovery.
    European journal of physical and rehabilitation medicine, 2008, Volume: 44, Issue:1

    Topics: Aged; Aged, 80 and over; Antidepressive Agents, Second-Generation; Citalopram; Depression; Female; F

2008
A stroke patient with a non-convulsive status epilepticus during citalopram therapy.
    European journal of neurology, 2002, Volume: 9, Issue:3

    Topics: Aged; Antidepressive Agents, Second-Generation; Citalopram; Depression; Female; Humans; Status Epile

2002