citalopram has been researched along with Sleep Wake Disorders in 21 studies
Citalopram: A furancarbonitrile that is one of the serotonin uptake inhibitors used as an antidepressant. The drug is also effective in reducing ethanol uptake in alcoholics and is used in depressed patients who also suffer from TARDIVE DYSKINESIA in preference to tricyclic antidepressants, which aggravate dyskinesia.
citalopram : A racemate comprising equimolar amounts of (R)-citalopram and its enantiomer, escitalopram. It is used as an antidepressant, although only escitalopram is active.
1-[3-(dimethylamino)propyl]-1-(4-fluorophenyl)-1,3-dihydro-2-benzofuran-5-carbonitrile : A nitrile that is 1,3-dihydro-2-benzofuran-5-carbonitrile in which one of the hydrogens at position 1 is replaced by a p-fluorophenyl group, while the other is replaced by a 3-(dimethylamino)propyl group.
Sleep Wake Disorders: Abnormal sleep-wake schedule or pattern associated with the CIRCADIAN RHYTHM which affect the length, timing, and/or rigidity of the sleep-wake cycle relative to the day-night cycle.
| Excerpt | Relevance | Reference |
|---|---|---|
| "To investigate the correlates of sleep disturbance and to assess escitalopram treatment effects of depression on sleep disturbance in patients with acute coronary syndrome (ACS)." | 9.20 | Correlates and Escitalopram Treatment Effects on Sleep Disturbance in Patients with Acute Coronary Syndrome: K-DEPACS and EsDEPACS. ( Ahn, Y; Bae, KY; Hong, YJ; Jeong, MH; Kang, HJ; Kim, JM; Kim, SW; Shin, IS; Stewart, R; Yoon, JS, 2015) |
| " Adverse effects were assessed by the Adverse Events Scale." | 7.01 | The therapeutic effects and safety of bright light therapy combined with escitalopram oxalate on insomnia in patients with poststroke depression. ( Chen, S; Feng, L; He, J; Luan, X; Wang, Q; Xiao, M, 2021) |
| "While dosage constraints must be considered because of citalopram's adverse effect profile, this agent's overall therapeutic effects in patients with Alzheimer's disease and agitation, in addition to efficacy for agitation/aggression, included reductions in the frequency of irritability, anxiety, and delusions; among patients who had these symptoms at week 9, they included a reduction in the severity of hallucinations but an increase in the severity of sleep/nighttime behavior disorders." | 5.22 | Effects of Citalopram on Neuropsychiatric Symptoms in Alzheimer's Dementia: Evidence From the CitAD Study. ( Devanand, DP; Drye, LT; Frangakis, C; Leonpacher, AK; Lyketsos, CG; Makino, KM; Mintzer, JE; Munro, CA; Newell, JA; Peters, ME; Pollock, BG; Porsteinsson, AP; Rosenberg, PB; Schneider, LS; Shade, DM; Weintraub, D; Yesavage, J, 2016) |
| "To investigate the correlates of sleep disturbance and to assess escitalopram treatment effects of depression on sleep disturbance in patients with acute coronary syndrome (ACS)." | 5.20 | Correlates and Escitalopram Treatment Effects on Sleep Disturbance in Patients with Acute Coronary Syndrome: K-DEPACS and EsDEPACS. ( Ahn, Y; Bae, KY; Hong, YJ; Jeong, MH; Kang, HJ; Kim, JM; Kim, SW; Shin, IS; Stewart, R; Yoon, JS, 2015) |
| " Adverse effects were assessed by the Adverse Events Scale." | 3.01 | The therapeutic effects and safety of bright light therapy combined with escitalopram oxalate on insomnia in patients with poststroke depression. ( Chen, S; Feng, L; He, J; Luan, X; Wang, Q; Xiao, M, 2021) |
| "Escitalopram is a dual serotonin reuptake inhibitor (SSRI) approved for the treatment of depression and anxiety disorders." | 2.72 | In vivo imaging of serotonin transporter occupancy by means of SPECT and [123I]ADAM in healthy subjects administered different doses of escitalopram or citalopram. ( Asenbaum, S; Attarbaschi, T; Dudczak, R; Geiss-Granadia, T; Holik, A; Kasper, S; Klein, N; Lanzenberger, R; Mossaheb, N; Pötzi, C; Sacher, J; Spindelegger, C; Tauscher, J, 2006) |
| "Disturbed sleep is a key symptom in major depressive disorder (MDD) and generalized anxiety disorder (GAD)." | 2.47 | Effects of escitalopram on sleep problems in patients with major depression or generalized anxiety disorder. ( Lopez, AG; Stein, DJ, 2011) |
| "Panic disorder is a common anxiety disorder, which has relatively often its onset during adolescence." | 2.39 | Sleep in panic disorders. ( Koponen, H; Leinonen, E; Lepola, U, 1994) |
| "Dabigatran is an anti-aggregation agent used for the treatment of atrial fibrillation." | 1.42 | Depressive symptoms associated with dabigatran: a case report. ( Enez Darcin, A; Eryilmaz, G; Gogcegoz Gul, I; Saglam, E, 2015) |
| "However, as his PTSD symptoms remitted, so did his tic symptoms." | 1.35 | Attenuation of apparent new-onset ocular tics with successful treatment of PTSD. ( Drouillard, GJ; Gallagher, MB; Hayes, PC; Weber, CL, 2009) |
| "Thirty youth with major depressive disorder (MDD) and 23 control youth reported on caffeine use, sleep, and affect in their natural environment using ecological momentary assessment at baseline and over 8 weeks, while MDD youth received treatment." | 1.35 | Caffeine consumption, sleep, and affect in the natural environments of depressed youth and healthy controls. ( Axelson, DA; Birmaher, B; Dahl, RE; Forbes, EE; Ryan, ND; Semel, M; Silk, JS; Whalen, DJ, 2008) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (4.76) | 18.7374 |
| 1990's | 1 (4.76) | 18.2507 |
| 2000's | 10 (47.62) | 29.6817 |
| 2010's | 6 (28.57) | 24.3611 |
| 2020's | 3 (14.29) | 2.80 |
| Authors | Studies |
|---|---|
| Szuhany, KL | 1 |
| Young, A | 1 |
| Mauro, C | 1 |
| Garcia de la Garza, A | 1 |
| Spandorfer, J | 1 |
| Lubin, R | 1 |
| Skritskaya, NA | 1 |
| Hoeppner, SS | 1 |
| Li, M | 1 |
| Pace-Schott, E | 1 |
| Zisook, S | 1 |
| Reynolds, CF | 1 |
| Shear, MK | 1 |
| Simon, NM | 1 |
| Xiao, M | 1 |
| Feng, L | 1 |
| Wang, Q | 1 |
| Luan, X | 1 |
| Chen, S | 1 |
| He, J | 1 |
| Shirazi, M | 1 |
| Jalalian, MN | 1 |
| Abed, M | 1 |
| Ghaemi, M | 1 |
| Shahsavand-Ananloo, E | 1 |
| Berenji, F | 1 |
| Sadeghniiat, K | 1 |
| Alimadadi, A | 1 |
| Zahiroddin, AR | 1 |
| Tabatabaee, M | 1 |
| Abbasi-Asl, M | 1 |
| Ghaeli, P | 1 |
| Eryilmaz, G | 1 |
| Enez Darcin, A | 1 |
| Saglam, E | 1 |
| Gogcegoz Gul, I | 1 |
| Kim, JM | 1 |
| Stewart, R | 1 |
| Bae, KY | 1 |
| Kang, HJ | 1 |
| Kim, SW | 1 |
| Shin, IS | 1 |
| Hong, YJ | 1 |
| Ahn, Y | 1 |
| Jeong, MH | 1 |
| Yoon, JS | 1 |
| Parthasarathy, S | 1 |
| Shetty, S | 1 |
| Combs, D | 1 |
| Leonpacher, AK | 1 |
| Peters, ME | 1 |
| Drye, LT | 1 |
| Makino, KM | 1 |
| Newell, JA | 1 |
| Devanand, DP | 1 |
| Frangakis, C | 1 |
| Munro, CA | 1 |
| Mintzer, JE | 1 |
| Pollock, BG | 1 |
| Rosenberg, PB | 1 |
| Schneider, LS | 1 |
| Shade, DM | 1 |
| Weintraub, D | 1 |
| Yesavage, J | 1 |
| Lyketsos, CG | 1 |
| Porsteinsson, AP | 1 |
| Hayes, PC | 1 |
| Weber, CL | 1 |
| Gallagher, MB | 1 |
| Drouillard, GJ | 1 |
| Volkmar, FR | 1 |
| Stein, DJ | 1 |
| Lopez, AG | 1 |
| Feltenstein, MW | 1 |
| Sufka, KJ | 1 |
| Lader, M | 1 |
| Andersen, HF | 1 |
| Baekdal, T | 1 |
| Fujiki, N | 1 |
| Klein, N | 1 |
| Sacher, J | 1 |
| Geiss-Granadia, T | 1 |
| Attarbaschi, T | 1 |
| Mossaheb, N | 1 |
| Lanzenberger, R | 1 |
| Pötzi, C | 1 |
| Holik, A | 1 |
| Spindelegger, C | 1 |
| Asenbaum, S | 1 |
| Dudczak, R | 1 |
| Tauscher, J | 1 |
| Kasper, S | 1 |
| Huuhka, K | 1 |
| Riutta, A | 1 |
| Haataja, R | 1 |
| Ylitalo, P | 1 |
| Leinonen, E | 2 |
| Whalen, DJ | 1 |
| Silk, JS | 1 |
| Semel, M | 1 |
| Forbes, EE | 1 |
| Ryan, ND | 1 |
| Axelson, DA | 1 |
| Birmaher, B | 1 |
| Dahl, RE | 1 |
| Popa, D | 1 |
| Léna, C | 1 |
| Alexandre, C | 1 |
| Adrien, J | 1 |
| Lepola, U | 1 |
| Koponen, H | 1 |
| Borba, CP | 1 |
| Henderson, DC | 1 |
| Gravem, A | 1 |
| Amthor, KF | 1 |
| Astrup, C | 1 |
| Elgen, K | 1 |
| Gjessing, LR | 1 |
| Gunby, B | 1 |
| Pettersen, RD | 1 |
| Kyrdalen, L | 1 |
| Vaadal, J | 1 |
| Ofsti, E | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Study to Investigate Melissa Officinalis L. Supplementation for Emotional Health and Sleep Disturbance: A Perspective, Randomized, Double-blinded, Placebo-controlled, Parallel-group Clinical Trial[NCT05602688] | 102 participants (Actual) | Interventional | 2023-01-03 | Completed | |||
| Citalopram Improves Vasomotor and Urogenital Syndromes in Mexican Patients With Post-menopause[NCT05346445] | 91 participants (Actual) | Interventional | 2021-01-20 | Completed | |||
| Efficacy and Safety of Escitalopram in the Treatment of Depressive Patients With Acute Coronary Artery Syndrome: A Double-blind Placebo-controlled Trial[NCT00419471] | Phase 4 | 300 participants (Actual) | Interventional | 2007-05-31 | Completed | ||
| Escitalopram and Sleep Architecture in Patients With Major Depressive Disorder[NCT00442481] | Phase 4 | 25 participants | Interventional | 2007-02-28 | Recruiting | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
2 reviews available for citalopram and Sleep Wake Disorders
| Article | Year |
|---|---|
Effects of escitalopram on sleep problems in patients with major depression or generalized anxiety disorder.
Topics: Adult; Anxiety Disorders; Citalopram; Depressive Disorder, Major; Female; Humans; Male; Middle Aged; | 2011 |
Sleep in panic disorders.
Topics: Adult; Child; Citalopram; Diagnosis, Differential; Dose-Response Relationship, Drug; Drug Administra | 1994 |
9 trials available for citalopram and Sleep Wake Disorders
| Article | Year |
|---|---|
Impact of sleep on complicated grief severity and outcomes.
Topics: Bereavement; Citalopram; Comorbidity; Depression; Female; Grief; Humans; Male; Middle Aged; Quality | 2020 |
The therapeutic effects and safety of bright light therapy combined with escitalopram oxalate on insomnia in patients with poststroke depression.
Topics: Citalopram; Depression; Humans; Phototherapy; Sleep Initiation and Maintenance Disorders; Sleep Wake | 2021 |
The Effectiveness of Melissa Officinalis L. versus Citalopram on Quality of Life of Menopausal Women with Sleep Disorder: A Randomized Double-Blind Clinical Trial.
Topics: Citalopram; Double-Blind Method; Female; Humans; Iran; Melissa; Middle Aged; Phytotherapy; Plant Ext | 2021 |
The Effectiveness of Melissa Officinalis L. versus Citalopram on Quality of Life of Menopausal Women with Sleep Disorder: A Randomized Double-Blind Clinical Trial.
Topics: Citalopram; Double-Blind Method; Female; Humans; Iran; Melissa; Middle Aged; Phytotherapy; Plant Ext | 2021 |
The Effectiveness of Melissa Officinalis L. versus Citalopram on Quality of Life of Menopausal Women with Sleep Disorder: A Randomized Double-Blind Clinical Trial.
Topics: Citalopram; Double-Blind Method; Female; Humans; Iran; Melissa; Middle Aged; Phytotherapy; Plant Ext | 2021 |
The Effectiveness of Melissa Officinalis L. versus Citalopram on Quality of Life of Menopausal Women with Sleep Disorder: A Randomized Double-Blind Clinical Trial.
Topics: Citalopram; Double-Blind Method; Female; Humans; Iran; Melissa; Middle Aged; Phytotherapy; Plant Ext | 2021 |
Correlates and Escitalopram Treatment Effects on Sleep Disturbance in Patients with Acute Coronary Syndrome: K-DEPACS and EsDEPACS.
Topics: Acute Coronary Syndrome; Adolescent; Adult; Age Factors; Aged; Aged, 80 and over; Aging; Citalopram; | 2015 |
Effects of Citalopram on Neuropsychiatric Symptoms in Alzheimer's Dementia: Evidence From the CitAD Study.
Topics: Alzheimer Disease; Antidepressive Agents, Second-Generation; Anxiety; Citalopram; Delusions; Female; | 2016 |
The effect of escitalopram on sleep problems in depressed patients.
Topics: Adolescent; Adult; Aged; Antidepressive Agents, Second-Generation; Citalopram; Depression; Double-Bl | 2005 |
In vivo imaging of serotonin transporter occupancy by means of SPECT and [123I]ADAM in healthy subjects administered different doses of escitalopram or citalopram.
Topics: Administration, Oral; Adult; Akathisia, Drug-Induced; Area Under Curve; Cerebellum; Cinanserin; Cita | 2006 |
The effect of CYP2C19 substrate on the metabolism of melatonin in the elderly: A randomized, double-blind, placebo-controlled study.
Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Aged; Aged, 80 and over; Anticonvulsants; Antidepressive Ag | 2006 |
A double-blind comparison of citalopram (Lu 10-171) and amitriptyline in depressed patients.
Topics: Adult; Aged; Amitriptyline; Citalopram; Clinical Trials as Topic; Depressive Disorder; Double-Blind | 1987 |
10 other studies available for citalopram and Sleep Wake Disorders
| Article | Year |
|---|---|
Comparing effects of citalopram with fluoxetine on sleep quality in patients with major depressive disorder.
Topics: Adolescent; Adult; Citalopram; Depressive Disorder, Major; Diagnostic and Statistical Manual of Ment | 2013 |
Depressive symptoms associated with dabigatran: a case report.
Topics: Antithrombins; Atrial Fibrillation; Citalopram; Dabigatran; Depression; Drug Interactions; Humans; M | 2015 |
Mend the Mind and Mind the "MCC".
Topics: Acute Coronary Syndrome; Citalopram; Depressive Disorder; Female; Humans; Male; Sleep Wake Disorders | 2015 |
Attenuation of apparent new-onset ocular tics with successful treatment of PTSD.
Topics: Alcoholism; Antidepressive Agents, Second-Generation; Citalopram; Combined Modality Therapy; Humans; | 2009 |
Citalopram treatment in children with autism spectrum disorders and high levels of repetitive behavior.
Topics: Adolescent; Autistic Disorder; Child; Child, Preschool; Citalopram; Double-Blind Method; Humans; Imp | 2009 |
Screening antidepressants in the chick separation-stress paradigm.
Topics: Animals; Antidepressive Agents; Anxiety, Separation; Chickens; Citalopram; Dose-Response Relationshi | 2005 |
Associated Professional Sleep Societies--SLEEP 2006 20th Anniversary Meeting. 17-22 June 2006, Salt Lake City, UT, USA.
Topics: Animals; Citalopram; Histamine Antagonists; Humans; Hypnotics and Sedatives; Indenes; Receptors, His | 2006 |
Caffeine consumption, sleep, and affect in the natural environments of depressed youth and healthy controls.
Topics: Adolescent; Affect; Anxiety Disorders; Attention Deficit Disorder with Hyperactivity; Beverages; Caf | 2008 |
Lasting syndrome of depression produced by reduction in serotonin uptake during postnatal development: evidence from sleep, stress, and behavior.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Analysis of Variance; Animals; Animals, Newborn; Antidepress | 2008 |
Citalopram and clozapine: potential drug interaction.
Topics: Adult; Citalopram; Clozapine; Confusion; Dose-Response Relationship, Drug; Drug Administration Sched | 2000 |