Page last updated: 2024-10-25

citalopram and Serotonin Syndrome

citalopram has been researched along with Serotonin Syndrome in 56 studies

Citalopram: A furancarbonitrile that is one of the serotonin uptake inhibitors used as an antidepressant. The drug is also effective in reducing ethanol uptake in alcoholics and is used in depressed patients who also suffer from TARDIVE DYSKINESIA in preference to tricyclic antidepressants, which aggravate dyskinesia.
citalopram : A racemate comprising equimolar amounts of (R)-citalopram and its enantiomer, escitalopram. It is used as an antidepressant, although only escitalopram is active.
1-[3-(dimethylamino)propyl]-1-(4-fluorophenyl)-1,3-dihydro-2-benzofuran-5-carbonitrile : A nitrile that is 1,3-dihydro-2-benzofuran-5-carbonitrile in which one of the hydrogens at position 1 is replaced by a p-fluorophenyl group, while the other is replaced by a 3-(dimethylamino)propyl group.

Serotonin Syndrome: An adverse drug interaction characterized by altered mental status, autonomic dysfunction, and neuromuscular abnormalities. It is most frequently caused by use of both serotonin reuptake inhibitors and monoamine oxidase inhibitors, leading to excess serotonin availability in the CNS at the serotonin 1A receptor.

Research Excerpts

ExcerptRelevanceReference
"Citalopram overdose may be associated with severe serotonin syndrome and further investigation is warranted to understand the impact of enzyme genotype on toxicity."7.91Citalopram overdose and severe serotonin syndrome in an intermediate metabolizing patient. ( Morris, AJ; Picard, L; Schult, RF; Wiegand, TJ, 2019)
"A 63-year-old woman with a history of long-standing depression, maintained on escitalopram, presented with altered mental status."7.85Serotonin syndrome caused by drug to drug interaction between escitalopram and dextromethorphan. ( Arcega, V; Dy, P; Ghali, W; Wolfe, W, 2017)
"Methylene blue (MB) has been used for additional blood pressure support in patients who develop severe, refractory vasoplegia; however, MB can induce serotonin syndrome, especially when used in conjunction with other serotonergic agents."7.83Serotonin Syndrome Following Methylene Blue Administration for Vasoplegic Syndrome. ( Hencken, L; Ly, N; Morgan, JA; To, L, 2016)
"Metaxalone has only recently been associated with serotonin syndrome."7.81Serotonin syndrome following metaxalone overdose and therapeutic use of a selective serotonin reuptake inhibitor. ( Cobb, T; Haswell, D; Hodgman, M; Martini, DI; Nacca, N, 2015)
"The authors reported a case of serotonin syndrome associated with combined therapy of monoamine oxidase-B inhibitors and selective serotonin reuptake inhibitor A 77-year-old Thai man had been taking escitalopram for depression for three years."7.81Combination of Escitalopram and Rasagiline Induced Serotonin Syndrome: A Case Report and Review Literature. ( Santimaleeworagun, W; Supasyndh, O; Suphanklang, J, 2015)
" The patient received a diagnosis of serotonin syndrome attributed to abrupt clozapine withdrawal with concomitant use of citalopram."7.79Serotonin syndrome associated with clozapine withdrawal. ( Burns, JD; Green, DM; Schembri, F; Stevenson, E, 2013)
" In the present report, we describe a case of serotonin syndrome in an 88-year-old woman receiving a low dose of escitalopram."7.78Serotonin syndrome during treatment with low dose of escitalopram associated with miconazole mucoadhesive tablet: a suspected drug interaction. ( Baptista, G; Eiden, C; Jeandel, C; Monguillot, P; Philibert, C, 2012)
"Our cases suggest supra-therapeutic dextromethorphan doses with a therapeutic amount of a SSRI are required for serotonin syndrome."7.74Dextromethorphan-induced serotonin syndrome. ( Brooks, DE; Pizon, AF; Schwartz, AR, 2008)
"Healthcare professionals should be aware of the possible development of serotonin syndrome as a complication of initiation of fentanyl and other phenylpiperidine opioids in patients treated with SSRIs."7.74Serotonin syndrome caused by interaction between citalopram and fentanyl. ( Ailawadhi, S; Baer, MR; Carlson, LA; Sung, KW, 2007)
"To study the characteristics of the linezolid-associated serotonin syndrome cases."7.73Linezolid-associated serotonin syndrome: what we can learn from cases reported so far. ( Grau, S; Marín-Casino, M; Mateu-de Antonio, J; Morales-Molina, JA, 2005)
" The first reported case of quetiapine and citalopram-associated serotonin syndrome is discussed with reference to a Medline, Embase, and PsycINFO literature search."7.73Quetiapine and citalopram: aetiological significances in serotonin syndrome. ( Marlowe, K; Schirgel, D, 2006)
" Although there are reports of serotonin syndrome developing after concomitant use of linezolid and the selective serotonin reuptake inhibitor paroxitene, this report concerns a patient receiving citalopram who developed thrombocytopenia, serotonin syndrome, and lactic acidosis and died following long-term linezolid therapy."7.72Serotonin syndrome after concomitant treatment with linezolid and citalopram. ( Bernard, L; Hoffmeyer, P; Lew, D; Stern, R, 2003)
"The present paper describes a case of serotonin syndrome (SS), which developed in a patient with bipolar affective disorder after the addition of olanzapine to her regimen of lithium and citalopram."7.71Can olanzapine be implicated in causing serotonin syndrome? ( Haslett, CD; Kumar, S, 2002)
"Citalopram is a very potent and highly selective inhibitor of neuronal serotonin (5-hydroxytryptamine, or 5-HT)."5.34First time, low dose citalopram use-related serotonin syndrome. ( Eraydin, I; Gunduz, A; Hos, U; Kalkan, A; Turedi, S, 2007)
"Serotonin syndrome is a disorder resulting from excess stimulation of serotonin and is associated with drug interaction, single-drug therapy, and overdose."5.33Citalopram-induced serotonin syndrome: a case report. ( Huang, CT; Liu, HW; Tsai, JH; Tseng, WP; Wu, MT, 2005)
"The serotonin syndrome is caused by a drug-induced increase of the intrasynaptic serotonin concentration."5.33[The serotonin syndrome. Fatal course of intoxication with citalopram and moclobemide]. ( Cassens, S; Neumann, P; Nickel, EA; Quintel, M, 2006)
"Citalopram overdose may be associated with severe serotonin syndrome and further investigation is warranted to understand the impact of enzyme genotype on toxicity."3.91Citalopram overdose and severe serotonin syndrome in an intermediate metabolizing patient. ( Morris, AJ; Picard, L; Schult, RF; Wiegand, TJ, 2019)
" The patient was diagnosed with serotonin syndrome, attributed to the coadministration of 2 commonly prescribed medications (citalopram and omeprazole)."3.88Hyperpyrexia in a patient with a left ventricular assist device: a diagnosis beyond the obvious. ( Charitos, C; Kapelios, CJ; Tsamatsoulis, M, 2018)
"A 63-year-old woman with a history of long-standing depression, maintained on escitalopram, presented with altered mental status."3.85Serotonin syndrome caused by drug to drug interaction between escitalopram and dextromethorphan. ( Arcega, V; Dy, P; Ghali, W; Wolfe, W, 2017)
"Methylene blue (MB) has been used for additional blood pressure support in patients who develop severe, refractory vasoplegia; however, MB can induce serotonin syndrome, especially when used in conjunction with other serotonergic agents."3.83Serotonin Syndrome Following Methylene Blue Administration for Vasoplegic Syndrome. ( Hencken, L; Ly, N; Morgan, JA; To, L, 2016)
"Metaxalone has only recently been associated with serotonin syndrome."3.81Serotonin syndrome following metaxalone overdose and therapeutic use of a selective serotonin reuptake inhibitor. ( Cobb, T; Haswell, D; Hodgman, M; Martini, DI; Nacca, N, 2015)
"Citalopram is a selective serotonin reuptake inhibitor (SSRI) with cardiac and neurologic toxicities as well as the potential for serotonin syndrome."3.81Citalopram Overdose: a Fatal Case. ( Kraai, EP; Seifert, SA, 2015)
"The authors reported a case of serotonin syndrome associated with combined therapy of monoamine oxidase-B inhibitors and selective serotonin reuptake inhibitor A 77-year-old Thai man had been taking escitalopram for depression for three years."3.81Combination of Escitalopram and Rasagiline Induced Serotonin Syndrome: A Case Report and Review Literature. ( Santimaleeworagun, W; Supasyndh, O; Suphanklang, J, 2015)
" The patient received a diagnosis of serotonin syndrome attributed to abrupt clozapine withdrawal with concomitant use of citalopram."3.79Serotonin syndrome associated with clozapine withdrawal. ( Burns, JD; Green, DM; Schembri, F; Stevenson, E, 2013)
"We report a case of serotonin syndrome caused by interaction between nasal fentanyl, oxycodone and escitalopram."3.76[Serotoninergic antidepressants and opiate analgesics: a sometimes-painful association. A case report]. ( Lefebvre-Kuntz, D; Reich, M, 2010)
"The patient was referred to a neurologist, who diagnosed serotonin syndrome related to the use of citalopram."3.74Misdiagnosis of serotonin syndrome as fibromyalgia and the role of physical therapists. ( Alnwick, GM, 2008)
"Healthcare professionals should be aware of the possible development of serotonin syndrome as a complication of initiation of fentanyl and other phenylpiperidine opioids in patients treated with SSRIs."3.74Serotonin syndrome caused by interaction between citalopram and fentanyl. ( Ailawadhi, S; Baer, MR; Carlson, LA; Sung, KW, 2007)
"Our cases suggest supra-therapeutic dextromethorphan doses with a therapeutic amount of a SSRI are required for serotonin syndrome."3.74Dextromethorphan-induced serotonin syndrome. ( Brooks, DE; Pizon, AF; Schwartz, AR, 2008)
"To study the characteristics of the linezolid-associated serotonin syndrome cases."3.73Linezolid-associated serotonin syndrome: what we can learn from cases reported so far. ( Grau, S; Marín-Casino, M; Mateu-de Antonio, J; Morales-Molina, JA, 2005)
" The first reported case of quetiapine and citalopram-associated serotonin syndrome is discussed with reference to a Medline, Embase, and PsycINFO literature search."3.73Quetiapine and citalopram: aetiological significances in serotonin syndrome. ( Marlowe, K; Schirgel, D, 2006)
" Although there are reports of serotonin syndrome developing after concomitant use of linezolid and the selective serotonin reuptake inhibitor paroxitene, this report concerns a patient receiving citalopram who developed thrombocytopenia, serotonin syndrome, and lactic acidosis and died following long-term linezolid therapy."3.72Serotonin syndrome after concomitant treatment with linezolid and citalopram. ( Bernard, L; Hoffmeyer, P; Lew, D; Stern, R, 2003)
"The present paper describes a case of serotonin syndrome (SS), which developed in a patient with bipolar affective disorder after the addition of olanzapine to her regimen of lithium and citalopram."3.71Can olanzapine be implicated in causing serotonin syndrome? ( Haslett, CD; Kumar, S, 2002)
"There is a potential risk that 5-HT(1A) receptor blockade combined with blockade of the 5-HT transporter by an SSRI may cause a toxic increase in 5-HT within the synapse, sparking concern for 'serotonin syndrome', a rare but potentially life threatening condition."2.77Concomitant blockade of 5-HT(1A) receptor and 5-HT transporter: use of the Hunter Serotonin toxicity criteria in a clinical pharmacology study. ( Chalon, S; Connell, J; Parks, V; Philipp, AW; Plotka, A; Raje, S; Schechter, LE, 2012)
"The serotonin toxicity (ST) is a potentially life-threatening adverse drug reaction results from therapeutic drug use, intentional self-poisoning, or inadvertent interactions between drugs."2.47Serotonin toxicity: a short review of the literature and two case reports involving citalopram. ( Bruno, G; Canevelli, M; Lenzi, GL; Piacentini, E; Pietracupa, S; Talarico, G; Tosto, G, 2011)
"Serotonin syndrome is due to excess serotonin in the nervous system."1.56Serotonin syndrome in a Parkinson disease patient after intake of an ethanol-containing homeopathic medication. ( Del Rosario, MM; Jamora, RDG; Suratos, CTR, 2020)
"Linezolid was discontinued after 5 days and the patient's symptoms resolved."1.48Linezolid-associated serotonin toxicity after escitalopram discontinuation: concomitant drug considerations. ( Ebied, A; Khoury, A; Penny, ES; Runnstrom, M, 2018)
"However, serotonin syndrome, seizures, electrocardiographic abnormalities as well as respiratory failure and death have been described in patients with citalopram overdose."1.38Mechanisms of high-dose citalopram-induced death in a rat model. ( Baud, FJ; Beaune, S; Callebert, J; Juvin, P; Mégarbane, B; Risède, P, 2012)
"Serotonin syndrome is an iatrogenic disorder that results from serotonergic overactivity."1.36A perfect storm in the emergency department. ( Wijdicks, EF; Yee, AH, 2010)
"Escitalopram was discontinued and the patient did not have any further seizure activity."1.35Serotonergic antidepressants and linezolid: a retrospective chart review and presentation of cases. ( Canepa, EA; Lorenz, RA; Vandenberg, AM, 2008)
"The serotonin syndrome is a rare toxicological emergency increasingly seen in emergency practice, secondary to increased use of proserotinergic drugs."1.35Serotonin syndrome in a patient taking Lexapro and Flexeril: a case report. ( Day, LT; Jeanmonod, RK, 2008)
"Citalopram is a very potent and highly selective inhibitor of neuronal serotonin (5-hydroxytryptamine, or 5-HT)."1.34First time, low dose citalopram use-related serotonin syndrome. ( Eraydin, I; Gunduz, A; Hos, U; Kalkan, A; Turedi, S, 2007)
"Serotonin syndrome is a disorder resulting from excess stimulation of serotonin and is associated with drug interaction, single-drug therapy, and overdose."1.33Citalopram-induced serotonin syndrome: a case report. ( Huang, CT; Liu, HW; Tsai, JH; Tseng, WP; Wu, MT, 2005)
" Two weeks after the increase of the dosage of sertraline, the patient developed a full-blown SS, which resolved completely after the discontinuation of the drug."1.32Repetition of serotonin syndrome after reexposure to SSRI--a case report. ( Modestin, J; Tomaselli, G, 2004)

Research

Studies (56)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (1.79)18.2507
2000's24 (42.86)29.6817
2010's29 (51.79)24.3611
2020's2 (3.57)2.80

Authors

AuthorsStudies
Nunes, JC1
Botas, JL1
Suratos, CTR1
Del Rosario, MM1
Jamora, RDG1
Schumacher, LD1
Blumer, V1
Chaparro, SV1
Dy, P1
Arcega, V1
Ghali, W1
Wolfe, W1
de Dios, I1
Rialp, G1
Franco, S1
Romero, M1
Ortega, M1
Nieto, Y1
Tsamatsoulis, M1
Kapelios, CJ1
Charitos, C1
Khoury, A1
Runnstrom, M1
Ebied, A1
Penny, ES1
Schult, RF1
Morris, AJ1
Picard, L1
Wiegand, TJ1
Proudfoot, M1
Gormley, J1
Stevenson, E1
Schembri, F1
Green, DM1
Burns, JD1
O'Brien, FE1
O'Connor, RM1
Clarke, G1
Donovan, MD1
Dinan, TG1
Griffin, BT1
Cryan, JF1
Richter, T1
Paluch, Z1
Alusik, S1
Ansermot, N1
Hodel, PF2
Eap, CB1
Kraai, EP1
Seifert, SA1
Martini, DI1
Nacca, N1
Haswell, D1
Cobb, T1
Hodgman, M1
Hencken, L1
To, L1
Ly, N1
Morgan, JA1
Suphanklang, J1
Santimaleeworagun, W1
Supasyndh, O1
Deuschle, M1
Böhringer, A1
Meyer-Lindenberg, A1
Sartorius, A1
Schuch, LG1
Yip, A1
Nouri, KF1
Gregersen, M1
Cason, B1
Kukreja, J1
Wozniak, C1
Brzezinski, M1
Gollapudy, S1
Cronin, DC1
Pagel, PS1
Boettcher, BT1
Lorenz, RA1
Vandenberg, AM1
Canepa, EA1
Khavandi, A1
Whitaker, J1
Gonna, H1
Day, LT1
Jeanmonod, RK1
Schwartz, AR1
Pizon, AF1
Brooks, DE1
Yee, AH1
Wijdicks, EF1
Lugassy, DM1
Hoffman, RS1
Chessex, N1
Reich, M1
Lefebvre-Kuntz, D1
Peacock, LE1
Wright, F1
Go, AC1
Golightly, LK1
Barber, GR1
Barron, MA1
Talarico, G1
Tosto, G1
Pietracupa, S1
Piacentini, E1
Canevelli, M1
Lenzi, GL1
Bruno, G1
Parks, V1
Philipp, AW1
Raje, S1
Plotka, A1
Schechter, LE1
Connell, J1
Chalon, S1
Baptista, G1
Eiden, C1
Monguillot, P1
Philibert, C1
Jeandel, C1
Beaune, S1
Callebert, J1
Baud, FJ1
Risède, P1
Juvin, P1
Mégarbane, B1
I Lorenzini, K1
Calmy, A1
Ambrosioni, J1
Assouline, B1
Daali, Y1
Fathi, M1
Rebsamen, M1
Desmeules, J1
Samer, CF1
Shahani, L1
Haslett, CD1
Kumar, S1
Isbister, GK1
Downes, F1
Whyte, IM1
Bernard, L1
Stern, R1
Lew, D1
Hoffmeyer, P1
Birmes, P1
Coppin, D1
Schmitt, L1
Lauque, D1
Mahlberg, R1
Kunz, D1
Sasse, J1
Kirchheiner, J1
Tomaselli, G1
Modestin, J1
Tseng, WP1
Tsai, JH1
Wu, MT1
Huang, CT1
Liu, HW1
Kozian, R1
Morales-Molina, JA1
Mateu-de Antonio, J1
Marín-Casino, M1
Grau, S1
Marlowe, K1
Schirgel, D1
Cassens, S1
Nickel, EA1
Quintel, M1
Neumann, P1
Ailawadhi, S1
Sung, KW1
Carlson, LA1
Baer, MR1
Huska, MT1
Catalano, G1
Catalano, MC1
Turedi, S1
Eraydin, I1
Gunduz, A1
Kalkan, A1
Hos, U1
Lang, PO1
Hasso, Y1
Hilleret, H1
Vogt-Ferrier, N1
Wong, WM1
Hasemann, S1
Schwarz, M1
Zill, P1
Koller, G1
Soyka, M1
Preuss, UW1
Alnwick, GM1
Gumà, M1
Clemente, F1
Segura, A1
Costa, J1
Voirol, P1
Zullino, D1
Baumann, P1
Lantz, MS1
Dams, R1
Benijts, TH1
Lambert, WE1
Van Bocxlaer, JF1
Van Varenbergh, D1
Van Peteghem, C1
De Leenheer, AP1

Reviews

5 reviews available for citalopram and Serotonin Syndrome

ArticleYear
Methylene blue-induced serotonin syndrome after left ventricular assist device implantation: A case report and literature review.
    The Journal of thoracic and cardiovascular surgery, 2017, Volume: 154, Issue:3

    Topics: Citalopram; Drug Synergism; Heart-Assist Devices; Humans; Male; Methylene Blue; Middle Aged; Postope

2017
The non-antidepressant effects of citalopram: a clinician's perspective.
    Neuro endocrinology letters, 2014, Volume: 35, Issue:1

    Topics: Citalopram; Humans; Hyponatremia; Osteoporosis; Platelet Aggregation Inhibitors; Romano-Ward Syndrom

2014
Serotonin toxicity: a short review of the literature and two case reports involving citalopram.
    Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology, 2011, Volume: 32, Issue:3

    Topics: Aged; Cimetidine; Citalopram; Cytochrome P-450 CYP2D6; Cytochrome P-450 CYP2D6 Inhibitors; Female; F

2011
Serotonin syndrome: a brief review.
    CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne, 2003, May-27, Volume: 168, Issue:11

    Topics: Antidepressive Agents, Second-Generation; Citalopram; Diagnosis, Differential; Female; Fluid Therapy

2003
[The serotoninergic syndrome: moclobemide and citalopram].
    Medicina clinica, 1999, Nov-20, Volume: 113, Issue:17

    Topics: Adult; Citalopram; Drug Interactions; Humans; Male; Moclobemide; Monoamine Oxidase Inhibitors; Selec

1999

Trials

2 trials available for citalopram and Serotonin Syndrome

ArticleYear
Concomitant blockade of 5-HT(1A) receptor and 5-HT transporter: use of the Hunter Serotonin toxicity criteria in a clinical pharmacology study.
    European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology, 2012, Volume: 22, Issue:2

    Topics: Adult; Body Temperature; Citalopram; Cross-Over Studies; Dioxanes; Dose-Response Relationship, Drug;

2012
Citalopram neuropharmacological challenge in alcohol-dependent patients and controls: pharmacogenetic, endocrine and psychobehavioral results.
    Pharmacopsychiatry, 2008, Volume: 41, Issue:2

    Topics: Adrenocorticotropic Hormone; Adult; Alcoholism; Alleles; Antidepressive Agents; Anxiety; Behavior; C

2008

Other Studies

49 other studies available for citalopram and Serotonin Syndrome

ArticleYear
A Serotonin "Cocktail".
    The primary care companion for CNS disorders, 2020, 07-02, Volume: 22, Issue:4

    Topics: Buspirone; Citalopram; Depression; Drug Therapy, Combination; Female; Humans; Middle Aged; Selective

2020
Serotonin syndrome in a Parkinson disease patient after intake of an ethanol-containing homeopathic medication.
    Neurodegenerative disease management, 2020, Volume: 10, Issue:4

    Topics: Aged; Citalopram; Drug Interactions; Ethanol; Female; Homeopathy; Humans; Indans; Parkinson Disease;

2020
Serotonin syndrome caused by drug to drug interaction between escitalopram and dextromethorphan.
    BMJ case reports, 2017, Aug-07, Volume: 2017

    Topics: Antitussive Agents; Citalopram; Cough; Depression; Dextromethorphan; Drug Interactions; Female; Huma

2017
The role of chronic nutritional supplements consumption in a fulminant serotonin syndrome due to citalopram intoxication.
    Medicina intensiva, 2019, Volume: 43, Issue:9

    Topics: Adult; Alcohol Drinking; Antidepressive Agents, Second-Generation; Citalopram; Depression; Dietary S

2019
Hyperpyrexia in a patient with a left ventricular assist device: a diagnosis beyond the obvious.
    Interactive cardiovascular and thoracic surgery, 2018, 05-01, Volume: 26, Issue:5

    Topics: Aged; Citalopram; Fever; Heart Failure; Heart-Assist Devices; Humans; Male; Omeprazole; Proton Pump

2018
Linezolid-associated serotonin toxicity after escitalopram discontinuation: concomitant drug considerations.
    BMJ case reports, 2018, Oct-30, Volume: 2018

    Topics: Aged; Anti-Anxiety Agents; Anti-Bacterial Agents; Citalopram; Diagnosis, Differential; Drug Interact

2018
Citalopram overdose and severe serotonin syndrome in an intermediate metabolizing patient.
    The American journal of emergency medicine, 2019, Volume: 37, Issue:10

    Topics: Adult; Citalopram; Cytochrome P-450 CYP2C19; Drug Overdose; Female; Genotype; Humans; Pharmacogenomi

2019
Serotonin syndrome: pills, thrills and shoulder aches.
    BMJ case reports, 2013, Feb-20, Volume: 2013

    Topics: Accidental Falls; Citalopram; Depression; Diagnosis, Differential; Humans; Male; Selective Serotonin

2013
Serotonin syndrome associated with clozapine withdrawal.
    JAMA neurology, 2013, Volume: 70, Issue:8

    Topics: Benzodiazepines; Citalopram; Clozapine; Cyproheptadine; Female; Humans; Middle Aged; Selective Serot

2013
The P-glycoprotein inhibitor cyclosporin A differentially influences behavioural and neurochemical responses to the antidepressant escitalopram.
    Behavioural brain research, 2014, Mar-15, Volume: 261

    Topics: 5-Hydroxytryptophan; Animals; Antidepressive Agents; Behavior, Animal; Brain; Citalopram; Cyclospori

2014
Serotonin toxicity after addition of mirtazapine to escitalopram.
    Journal of clinical psychopharmacology, 2014, Volume: 34, Issue:4

    Topics: Adult; Antidepressive Agents; Citalopram; Drug Therapy, Combination; Female; Humans; Mianserin; Mirt

2014
Citalopram Overdose: a Fatal Case.
    Journal of medical toxicology : official journal of the American College of Medical Toxicology, 2015, Volume: 11, Issue:2

    Topics: Adult; Cardiopulmonary Resuscitation; Citalopram; Drug Overdose; Electrocardiography; Fatal Outcome;

2015
Serotonin syndrome following metaxalone overdose and therapeutic use of a selective serotonin reuptake inhibitor.
    Clinical toxicology (Philadelphia, Pa.), 2015, Volume: 53, Issue:3

    Topics: Adult; Citalopram; Drug Interactions; Drug Overdose; Female; Humans; Male; Neuromuscular Agents; Oxa

2015
Serotonin Syndrome Following Methylene Blue Administration for Vasoplegic Syndrome.
    Journal of cardiac surgery, 2016, Volume: 31, Issue:4

    Topics: Citalopram; Drug Synergism; Female; Heart-Assist Devices; Humans; Methylene Blue; Middle Aged; Prost

2016
Combination of Escitalopram and Rasagiline Induced Serotonin Syndrome: A Case Report and Review Literature.
    Journal of the Medical Association of Thailand = Chotmaihet thangphaet, 2015, Volume: 98, Issue:12

    Topics: Aged; Citalopram; Depression; Humans; Indans; Male; Parkinson Disease; Selective Serotonin Reuptake

2015
Electroconvulsive Therapy Induces Transient Sensitivity for a Serotonin Syndrome: A Case Report.
    Pharmacopsychiatry, 2017, Volume: 50, Issue:1

    Topics: Citalopram; Electroconvulsive Therapy; Female; Humans; Hypersensitivity; Lithium Carbonate; Middle A

2017
Serotonin Syndrome Following an Uncomplicated Orthopedic Surgery in a Patient With Post-Traumatic Stress Disorder.
    Military medicine, 2016, Volume: 181, Issue:9

    Topics: Adult; Citalopram; Diskectomy; Drug-Related Side Effects and Adverse Reactions; Humans; Low Back Pai

2016
Serotonin Syndrome Resulting From Acute Decompensation of Nonalcoholic Steatohepatitis Cirrhosis in a Patient Chronically Treated With Citalopram and Tramadol.
    Journal of cardiothoracic and vascular anesthesia, 2017, Volume: 31, Issue:4

    Topics: Citalopram; Drug Administration Schedule; Female; Humans; Middle Aged; Non-alcoholic Fatty Liver Dis

2017
Serotonergic antidepressants and linezolid: a retrospective chart review and presentation of cases.
    International journal of psychiatry in medicine, 2008, Volume: 38, Issue:1

    Topics: Adult; Aged; Aged, 80 and over; Anti-Bacterial Agents; Child, Preschool; Citalopram; Depressive Diso

2008
Serotonin toxicity precipitated by concomitant use of citalopram and methylene blue.
    The Medical journal of Australia, 2008, Nov-03, Volume: 189, Issue:9

    Topics: Adult; Citalopram; Coloring Agents; Drug Interactions; Female; Humans; Methylene Blue; Parathyroidec

2008
Serotonin syndrome in a patient taking Lexapro and Flexeril: a case report.
    The American journal of emergency medicine, 2008, Volume: 26, Issue:9

    Topics: Adult; Amitriptyline; Citalopram; Female; Humans; Selective Serotonin Reuptake Inhibitors; Serotonin

2008
Dextromethorphan-induced serotonin syndrome.
    Clinical toxicology (Philadelphia, Pa.), 2008, Volume: 46, Issue:8

    Topics: Antitussive Agents; Child; Citalopram; Dextromethorphan; Drug Interactions; Humans; Male; Selective

2008
A perfect storm in the emergency department.
    Neurocritical care, 2010, Volume: 12, Issue:2

    Topics: Aged; Alzheimer Disease; Citalopram; Drug Therapy, Combination; Female; Humans; Iatrogenic Disease;

2010
In response to van Gorp F. et al. Escitalopram overdose.
    Annals of emergency medicine, 2010, Volume: 55, Issue:1

    Topics: Citalopram; Electrocardiography; Humans; Long QT Syndrome; Medical History Taking; Selective Seroton

2010
[Serotoninergic antidepressants and opiate analgesics: a sometimes-painful association. A case report].
    L'Encephale, 2010, Volume: 36 Suppl 2

    Topics: Adenocarcinoma; Administration, Intranasal; Administration, Oral; Aged; Analgesics, Opioid; Antidepr

2010
Serotonin syndrome secondary to tramadol and citalopram.
    Age and ageing, 2011, Volume: 40, Issue:4

    Topics: Aged; Analgesics, Opioid; Citalopram; Female; Humans; Selective Serotonin Reuptake Inhibitors; Serot

2011
Linezolid interaction with serotonin reuptake inhibitors: report of two cases and incidence assessment.
    Drug metabolism and drug interactions, 2010, Volume: 25, Issue:1-4

    Topics: Acetamides; Anti-Infective Agents; Citalopram; Drug Interactions; Female; Humans; Linezolid; Male; M

2010
Serotonin syndrome during treatment with low dose of escitalopram associated with miconazole mucoadhesive tablet: a suspected drug interaction.
    International psychogeriatrics, 2012, Volume: 24, Issue:5

    Topics: Aged, 80 and over; Antifungal Agents; Citalopram; Drug Delivery Systems; Drug Interactions; Female;

2012
Mechanisms of high-dose citalopram-induced death in a rat model.
    Toxicology, 2012, Dec-16, Volume: 302, Issue:2-3

    Topics: Animals; Body Temperature; Citalopram; Cyproheptadine; Diazepam; Dose-Response Relationship, Drug; L

2012
Serotonin syndrome following drug-drug interactions and CYP2D6 and CYP2C19 genetic polymorphisms in an HIV-infected patient.
    AIDS (London, England), 2012, Nov-28, Volume: 26, Issue:18

    Topics: Antidepressive Agents, Second-Generation; Aryl Hydrocarbon Hydroxylases; Citalopram; Coinfection; Cy

2012
Tramadol precipitating serotonin syndrome in a patient on antidepressants.
    The Journal of neuropsychiatry and clinical neurosciences, 2012,Fall, Volume: 24, Issue:4

    Topics: Analgesics, Opioid; Antidepressive Agents; Bupropion; Citalopram; Depressive Disorder; Drug Therapy,

2012
Can olanzapine be implicated in causing serotonin syndrome?
    Psychiatry and clinical neurosciences, 2002, Volume: 56, Issue:5

    Topics: Antipsychotic Agents; Benzodiazepines; Bipolar Disorder; Citalopram; Female; Humans; Lithium Chlorid

2002
Olanzapine and serotonin toxicity.
    Psychiatry and clinical neurosciences, 2003, Volume: 57, Issue:2

    Topics: Antipsychotic Agents; Benzodiazepines; Citalopram; Drug Therapy, Combination; Humans; Olanzapine; Pa

2003
Serotonin syndrome after concomitant treatment with linezolid and citalopram.
    Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2003, May-01, Volume: 36, Issue:9

    Topics: Acetamides; Acidosis, Lactic; Citalopram; Drug Combinations; Humans; Linezolid; Oxazolidinones; Prot

2003
Serotonin syndrome with tramadol and citalopram.
    The American journal of psychiatry, 2004, Volume: 161, Issue:6

    Topics: Aged; Citalopram; Depressive Disorder; Drug Therapy, Combination; Female; Humans; Narcotics; Pain; S

2004
Repetition of serotonin syndrome after reexposure to SSRI--a case report.
    Pharmacopsychiatry, 2004, Volume: 37, Issue:5

    Topics: Citalopram; Depressive Disorder, Major; Female; Humans; Middle Aged; Recurrence; Selective Serotonin

2004
Citalopram-induced serotonin syndrome: a case report.
    The Kaohsiung journal of medical sciences, 2005, Volume: 21, Issue:7

    Topics: Adult; Citalopram; Diagnosis, Differential; Humans; Male; Neuroleptic Malignant Syndrome; Selective

2005
[The serotonin syndrome].
    Psychiatrische Praxis, 2005, Volume: 32, Issue:7

    Topics: Aged; Antipsychotic Agents; Citalopram; Depressive Disorder; Dibenzothiepins; Dose-Response Relation

2005
Linezolid-associated serotonin syndrome: what we can learn from cases reported so far.
    The Journal of antimicrobial chemotherapy, 2005, Volume: 56, Issue:6

    Topics: Acetamides; Adult; Age Factors; Aged; Aged, 80 and over; Anti-Bacterial Agents; Bacterial Infections

2005
Quetiapine and citalopram: aetiological significances in serotonin syndrome.
    The New Zealand medical journal, 2006, Jul-07, Volume: 119, Issue:1237

    Topics: Adult; Alprazolam; Anti-Anxiety Agents; Antipsychotic Agents; Bipolar Disorder; Citalopram; Dibenzot

2006
[The serotonin syndrome. Fatal course of intoxication with citalopram and moclobemide].
    Der Anaesthesist, 2006, Volume: 55, Issue:11

    Topics: Adult; Citalopram; Electrocardiography; Emergency Medical Services; Fatal Outcome; Female; Humans; M

2006
Serotonin syndrome caused by interaction between citalopram and fentanyl.
    Journal of clinical pharmacy and therapeutics, 2007, Volume: 32, Issue:2

    Topics: Aged; Citalopram; Drug Interactions; Drug Therapy, Combination; Fentanyl; Humans; Myelodysplastic Sy

2007
Serotonin syndrome associated with the use of escitalopram.
    CNS spectrums, 2007, Volume: 12, Issue:4

    Topics: Adult; Citalopram; Critical Care; Diagnosis, Differential; Dose-Response Relationship, Drug; Drug In

2007
First time, low dose citalopram use-related serotonin syndrome.
    Neurotoxicology, 2007, Volume: 28, Issue:6

    Topics: Adult; Antidepressive Agents, Second-Generation; Citalopram; Confusion; Cyproheptadine; Fever; Fluid

2007
[Serotonin syndrome as a result of escitalopram and cyclosporin combination in an 84-year-old woman].
    La Revue de medecine interne, 2008, Volume: 29, Issue:7

    Topics: Aged, 80 and over; Citalopram; Cyclosporine; Delirium; Drug Administration Schedule; Drug Therapy, C

2008
Misdiagnosis of serotonin syndrome as fibromyalgia and the role of physical therapists.
    Physical therapy, 2008, Volume: 88, Issue:6

    Topics: Adult; Citalopram; Diagnostic Errors; Female; Fibromyalgia; Humans; Physical Therapy Specialty; Phys

2008
Serotonin syndrome after small doses of citalopram or sertraline.
    Journal of clinical psychopharmacology, 2000, Volume: 20, Issue:6

    Topics: Citalopram; Humans; Male; Middle Aged; Selective Serotonin Reuptake Inhibitors; Serotonin Syndrome;

2000
Serotonin syndrome. A common but often unrecognized psychiatric condition.
    Geriatrics, 2001, Volume: 56, Issue:1

    Topics: Aged; Anxiety Disorders; Buspirone; Citalopram; Depression; Female; Humans; Selective Serotonin Reup

2001
A fatal case of serotonin syndrome after combined moclobemide-citalopram intoxication.
    Journal of analytical toxicology, 2001, Volume: 25, Issue:2

    Topics: Adult; Antidepressive Agents; Chromatography, High Pressure Liquid; Citalopram; Drug Combinations; E

2001