Page last updated: 2024-10-25

citalopram and Schizophrenia

citalopram has been researched along with Schizophrenia in 46 studies

Citalopram: A furancarbonitrile that is one of the serotonin uptake inhibitors used as an antidepressant. The drug is also effective in reducing ethanol uptake in alcoholics and is used in depressed patients who also suffer from TARDIVE DYSKINESIA in preference to tricyclic antidepressants, which aggravate dyskinesia.
citalopram : A racemate comprising equimolar amounts of (R)-citalopram and its enantiomer, escitalopram. It is used as an antidepressant, although only escitalopram is active.
1-[3-(dimethylamino)propyl]-1-(4-fluorophenyl)-1,3-dihydro-2-benzofuran-5-carbonitrile : A nitrile that is 1,3-dihydro-2-benzofuran-5-carbonitrile in which one of the hydrogens at position 1 is replaced by a p-fluorophenyl group, while the other is replaced by a 3-(dimethylamino)propyl group.

Schizophrenia: A severe emotional disorder of psychotic depth characteristically marked by a retreat from reality with delusion formation, HALLUCINATIONS, emotional disharmony, and regressive behavior.

Research Excerpts

ExcerptRelevanceReference
" We conducted a 52 week, placebo-controlled add-on trial of citalopram in patients with FES who did not meet criteria for major depression to determine whether maintenance therapy with citalopram would improve outcomes by preventing or improving negative and depressive symptoms."9.30Citalopram in first episode schizophrenia: The DECIFER trial. ( Ardekani, BA; Bello, I; Cather, C; Diminich, E; Fan, X; Freudenreich, O; Goff, DC; Holt, D; Li, C; Tang, Y; Troxel, A; Wang, J; Worthington, M; Wu, R; Zeng, B; Zhao, J, 2019)
"In this study, we assessed the efficacy of 2 pharmacodynamically different antidepressants, citalopram (a selective serotonin reuptake inhibitor) and reboxetine (a norepinephrine reuptake inhibitor), as adjunctive therapy to risperidone and olanzapine for the treatment of negative symptoms in schizophrenia."9.19Double-blind, placebo-controlled study of the efficacy of reboxetine and citalopram as adjuncts to atypical antipsychotics for negative symptoms of schizophrenia. ( Bernardo, M; Caballero, M; Corripio, I; Felipe, AE; Fernandez de Corres, B; González Piqueras, JC; Huerta, R; Ibáñez, A; Iniesta, R; López-Carrilero, R; Oliveira, C; Roca, M; Rodriguez-Jimenez, R; Sindreu, SD; Usall, J, 2014)
"Subsyndromal symptoms of depression in middle aged and older patients with schizophrenia responded to treatment with citalopram with lessening of depressive symptoms and improved functioning and quality of life."9.14Citalopram augmentation for subsyndromal symptoms of depression in middle-aged and older outpatients with schizophrenia and schizoaffective disorder: a randomized controlled trial. ( Fellows, I; Golshan, S; Jeste, DV; Kasckow, JW; Lehman, D; Mohamed, S; Solorzano, E; Zisook, S, 2009)
"To examine the effects of citalopram augmentation of antipsychotics on suicidal ideation in middle-aged and older people with schizophrenia and subthreshold depressive symptoms."9.14Augmentation with citalopram for suicidal ideation in middle-aged and older outpatients with schizophrenia and schizoaffective disorder who have subthreshold depressive symptoms: a randomized controlled trial. ( Fellows, I; Golshan, S; Kasckow, JW; Lanouette, NM; Mohamed, S; Rao, S; Vahia, I; Zisook, S, 2010)
"We conducted a 10-week single-blind trial of citalopram (20-40 mg/day) vs no citalopram augmentation in 19 middle-aged and elderly patients with schizophrenia hospitalized for more than six of the last 12 months."9.09Citalopram augmentation of antipsychotic treatment in older schizophrenia patients. ( Carroll, B; Jeste, DV; Kasckow, JW; Mohamed, S; Thallasinos, A; Zisook, S, 2001)
" The effect of the adjuvant selective serotonin reuptake inhibitor citalopram was assessed regarding the symptom dimensions of schizophrenia measured with the Positive and Negative Syndrome Scale (PANSS) and with the Hamilton Rating Scale for Depression (HRSD)."9.08Citalopram as an adjuvant in schizophrenia: further evidence for a serotonergic dimension in schizophrenia. ( Ahola, V; Lehto, H; Niemi, H; Saarijärvi, S; Salokangas, RK; Syvälahti, E; Taiminen, TJ, 1997)
"When schizophrenia patients have insufficient response to clozapine, pharmacological augmentation is often applied."8.88Pharmacological augmentation strategies for schizophrenia patients with insufficient response to clozapine: a quantitative literature review. ( Begemann, MJ; Leucht, S; Sommer, IE; Temmerman, A, 2012)
"The obtained results suggest that ADs may enhance the antipsychotic-like effect of aripiprazole in the animal tests used for evaluation of some positive and cognitive symptoms of schizophrenia."7.88Combined treatment with aripiprazole and antidepressants reversed some MK-801-induced schizophrenia-like symptoms in mice. ( Lorenc-Koci, E; Rogóż, Z; Wąsik, A, 2018)
"The present study demonstrates that co-administration of risperidone and escitalopram may be used to treat positive and negative symptoms of schizophrenia and will allow to minimize the drugs' side effects."7.85Risperidone and escitalopram co-administration: A potential treatment of schizophrenia symptoms with less side effects. ( Górska, A; Gołembiowska, K; Jurczak, A; Kamińska, K; Noworyta-Sokołowska, K; Rogóż, Z, 2017)
"Escitalopram was well tolerated, but was not more effective than placebo in the treatment of negative symptoms in patients with chronic schizophrenia."6.75Escitalopram in the treatment of negative symptoms in patients with chronic schizophrenia: a randomized double-blind placebo-controlled trial. ( Bodner, E; Iancu, I; Lowengrub, K; Piconne, AS; Tschernihovsky, E, 2010)
" This practice of polypharmacy increases the possibility for drug-drug interactions."5.38Drug-drug conditioning between citalopram and haloperidol or olanzapine in a conditioned avoidance response model: implications for polypharmacy in schizophrenia. ( Li, M; Sparkman, NL, 2012)
" We conducted a 52 week, placebo-controlled add-on trial of citalopram in patients with FES who did not meet criteria for major depression to determine whether maintenance therapy with citalopram would improve outcomes by preventing or improving negative and depressive symptoms."5.30Citalopram in first episode schizophrenia: The DECIFER trial. ( Ardekani, BA; Bello, I; Cather, C; Diminich, E; Fan, X; Freudenreich, O; Goff, DC; Holt, D; Li, C; Tang, Y; Troxel, A; Wang, J; Worthington, M; Wu, R; Zeng, B; Zhao, J, 2019)
"To establish the clinical effectiveness and cost-effectiveness of augmentation of antipsychotic medication with the antidepressant citalopram for the management of negative symptoms in schizophrenia."5.22Antidepressant Controlled Trial For Negative Symptoms In Schizophrenia (ACTIONS): a double-blind, placebo-controlled, randomised clinical trial. ( Baldwin, D; Barnes, TR; Costelloe, C; Craig, TK; Crawford, M; Geddes, J; Ismail, S; Keown, P; Killaspy, H; Kiss, N; Kumar, M; Leeson, VC; Lewis, G; Lewis, S; Osborn, D; Pathak, R; Paton, C; Simon, J; Taylor, S, 2016)
"In this study, we assessed the efficacy of 2 pharmacodynamically different antidepressants, citalopram (a selective serotonin reuptake inhibitor) and reboxetine (a norepinephrine reuptake inhibitor), as adjunctive therapy to risperidone and olanzapine for the treatment of negative symptoms in schizophrenia."5.19Double-blind, placebo-controlled study of the efficacy of reboxetine and citalopram as adjuncts to atypical antipsychotics for negative symptoms of schizophrenia. ( Bernardo, M; Caballero, M; Corripio, I; Felipe, AE; Fernandez de Corres, B; González Piqueras, JC; Huerta, R; Ibáñez, A; Iniesta, R; López-Carrilero, R; Oliveira, C; Roca, M; Rodriguez-Jimenez, R; Sindreu, SD; Usall, J, 2014)
"Subsyndromal symptoms of depression in middle aged and older patients with schizophrenia responded to treatment with citalopram with lessening of depressive symptoms and improved functioning and quality of life."5.14Citalopram augmentation for subsyndromal symptoms of depression in middle-aged and older outpatients with schizophrenia and schizoaffective disorder: a randomized controlled trial. ( Fellows, I; Golshan, S; Jeste, DV; Kasckow, JW; Lehman, D; Mohamed, S; Solorzano, E; Zisook, S, 2009)
"Citalopram augmentation of antipsychotic treatment in middle aged and older patients with schizophrenia and subsyndromal depression appears to improve social and mental health functioning as well as quality of life."5.14Treatment of subsyndromal depressive symptoms in middle-aged and older adults with schizophrenia: effect on functioning. ( Fellows, I; Golshan, S; Kasckow, J; Lanouette, N; Patterson, T; Solorzano, E; Zisook, S, 2010)
"To examine the effects of citalopram augmentation of antipsychotics on suicidal ideation in middle-aged and older people with schizophrenia and subthreshold depressive symptoms."5.14Augmentation with citalopram for suicidal ideation in middle-aged and older outpatients with schizophrenia and schizoaffective disorder who have subthreshold depressive symptoms: a randomized controlled trial. ( Fellows, I; Golshan, S; Kasckow, JW; Lanouette, NM; Mohamed, S; Rao, S; Vahia, I; Zisook, S, 2010)
"The authors hypothesized that age would moderate the response of patients with schizophrenia and subsyndromal depression (SSD) treated citalopram with depressive symptoms and other outcomes."5.14Treatment of subsyndromal depressive symptoms in middle-age and older patients with schizophrenia: effect of age on response. ( Fellows, I; Golshan, S; Kasckow, J; Meeks, T; Solorzano, E; Zisook, S, 2010)
"We conducted a 10-week single-blind trial of citalopram (20-40 mg/day) vs no citalopram augmentation in 19 middle-aged and elderly patients with schizophrenia hospitalized for more than six of the last 12 months."5.09Citalopram augmentation of antipsychotic treatment in older schizophrenia patients. ( Carroll, B; Jeste, DV; Kasckow, JW; Mohamed, S; Thallasinos, A; Zisook, S, 2001)
" The effect of the adjuvant selective serotonin reuptake inhibitor citalopram was assessed regarding the symptom dimensions of schizophrenia measured with the Positive and Negative Syndrome Scale (PANSS) and with the Hamilton Rating Scale for Depression (HRSD)."5.08Citalopram as an adjuvant in schizophrenia: further evidence for a serotonergic dimension in schizophrenia. ( Ahola, V; Lehto, H; Niemi, H; Saarijärvi, S; Salokangas, RK; Syvälahti, E; Taiminen, TJ, 1997)
"Our results provide tentative very low quality evidence that compared to placebo, NRIs (specifically reboxetine) may have a benefit on the negative symptoms of schizophrenia."4.98Selective noradrenaline reuptake inhibitors for schizophrenia. ( Horder, J; Matthews, PRL; Pearce, M, 2018)
" They also suggest that lithium for comorbid bipolar disorder, escitalopram for comorbid anxiety disorders, and the addition of CBT to standard drug treatment for comorbid schizophrenia may be effective."4.93Interventions for comorbid problem gambling and psychiatric disorders: Advancing a developing field of research. ( Dowling, NA; Lorains, FK; Merkouris, SS, 2016)
"When schizophrenia patients have insufficient response to clozapine, pharmacological augmentation is often applied."4.88Pharmacological augmentation strategies for schizophrenia patients with insufficient response to clozapine: a quantitative literature review. ( Begemann, MJ; Leucht, S; Sommer, IE; Temmerman, A, 2012)
"The obtained results suggest that ADs may enhance the antipsychotic-like effect of aripiprazole in the animal tests used for evaluation of some positive and cognitive symptoms of schizophrenia."3.88Combined treatment with aripiprazole and antidepressants reversed some MK-801-induced schizophrenia-like symptoms in mice. ( Lorenc-Koci, E; Rogóż, Z; Wąsik, A, 2018)
"The present study demonstrates that co-administration of risperidone and escitalopram may be used to treat positive and negative symptoms of schizophrenia and will allow to minimize the drugs' side effects."3.85Risperidone and escitalopram co-administration: A potential treatment of schizophrenia symptoms with less side effects. ( Górska, A; Gołembiowska, K; Jurczak, A; Kamińska, K; Noworyta-Sokołowska, K; Rogóż, Z, 2017)
" Moreover we also investigated their utility as adjunct treatment in depression in combination with the SSRI citalopram."3.83Alpha7 nicotinic acetylcholine receptor agonists and PAMs as adjunctive treatment in schizophrenia. An experimental study. ( Björkholm, C; Feltmann, K; Jardemark, K; Konradsson-Geuken, Å; Malmerfelt, A; Marcus, MM; Möller, A; Påhlsson, N; Schilström, B; Svensson, TH, 2016)
"While treatment of depression in major depressive disorder may partially ameliorate cognitive deficits, the cognitive effects of antidepressant medications in patients with schizophrenia or schizoaffective disorder and SSD are unknown."2.77Does antidepressant treatment improve cognition in older people with schizophrenia or schizoaffective disorder and comorbid subsyndromal depression? ( Dawes, SE; Golshan, S; Kasckow, J; Meeks, T; Mohamed, S; Palmer, BW; Zisook, S, 2012)
"Escitalopram was well tolerated, but was not more effective than placebo in the treatment of negative symptoms in patients with chronic schizophrenia."2.75Escitalopram in the treatment of negative symptoms in patients with chronic schizophrenia: a randomized double-blind placebo-controlled trial. ( Bodner, E; Iancu, I; Lowengrub, K; Piconne, AS; Tschernihovsky, E, 2010)
" This practice of polypharmacy increases the possibility for drug-drug interactions."1.38Drug-drug conditioning between citalopram and haloperidol or olanzapine in a conditioned avoidance response model: implications for polypharmacy in schizophrenia. ( Li, M; Sparkman, NL, 2012)
"Ziprasidone was tested as a positive control."1.33Effects of acute treatment with antidepressant drugs on sensorimotor gating deficits in rats. ( Andersen, MP; Hogg, S; Pouzet, B, 2005)

Research

Studies (46)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's7 (15.22)18.2507
2000's13 (28.26)29.6817
2010's23 (50.00)24.3611
2020's3 (6.52)2.80

Authors

AuthorsStudies
Qi, W2
Marx, J2
Zingman, M1
Li, Y2
Petkova, E1
Blessing, E2
Ardekani, B1
Sakalli Kani, A1
Cather, C3
Freudenreich, O3
Holt, D3
Zhao, J3
Wang, J3
Goff, DC3
Fischer, CE3
Namasivayam, A3
Crawford-Holland, L3
Hakobyan, N3
Schweizer, TA3
Munoz, DG3
Pollock, BG3
Li, C2
Ardekani, BA2
Hart, KL1
Bello, I2
Diminich, ED1
Tang, Y2
Worthington, M2
Zeng, B2
Wu, R2
Fan, X2
Troxel, A2
Matthews, PRL1
Horder, J1
Pearce, M1
Ding, N1
Li, Z1
Liu, Z1
Rogóż, Z2
Wąsik, A1
Lorenc-Koci, E1
Diminich, E1
Rubin-Kahana, DS1
Shelef, A1
Weizman, A3
Gothelf, D1
Timinski, I1
Spivak, B2
Stryjer, R2
Hinkelmann, K1
Yassouridis, A1
Kellner, M1
Jahn, H1
Wiedemann, K1
Raedler, TJ1
Tsai, CH1
Chen, TT1
Huang, WL1
Usall, J1
López-Carrilero, R1
Iniesta, R1
Roca, M1
Caballero, M1
Rodriguez-Jimenez, R1
Oliveira, C1
Bernardo, M1
Corripio, I1
Sindreu, SD1
González Piqueras, JC1
Felipe, AE1
Fernandez de Corres, B1
Ibáñez, A1
Huerta, R1
Dowling, NA1
Merkouris, SS1
Lorains, FK1
Barnes, TR1
Leeson, VC1
Paton, C1
Costelloe, C1
Simon, J1
Kiss, N1
Osborn, D1
Killaspy, H1
Craig, TK1
Lewis, S1
Keown, P1
Ismail, S1
Crawford, M1
Baldwin, D1
Lewis, G1
Geddes, J1
Kumar, M1
Pathak, R1
Taylor, S1
Marcus, MM1
Björkholm, C1
Malmerfelt, A1
Möller, A1
Påhlsson, N1
Konradsson-Geuken, Å1
Feltmann, K1
Jardemark, K1
Schilström, B1
Svensson, TH1
Tao, C1
Yan, W1
Lu, X1
Kamińska, K1
Noworyta-Sokołowska, K1
Jurczak, A1
Górska, A1
Gołembiowska, K1
Zisook, S8
Kasckow, JW4
Golshan, S6
Fellows, I5
Solorzano, E4
Lehman, D2
Mohamed, S6
Jeste, DV2
Wienberg, M1
Glenthoj, BY1
Jensen, KS1
Oranje, B1
Kasckow, J4
Lanouette, N1
Patterson, T1
Lanouette, NM1
Vahia, I1
Rao, S1
Iancu, I1
Tschernihovsky, E1
Bodner, E1
Piconne, AS1
Lowengrub, K1
Meeks, T2
Osatuke, K1
Reid, M1
Stiles, WB1
Sommer, IE1
Begemann, MJ1
Temmerman, A1
Leucht, S1
Dawes, SE1
Palmer, BW2
Sparkman, NL1
Li, M1
Dambinsky, Y1
Timinsky, I1
Green, T1
Kotler, M1
Kordon, A1
Broocks, A1
Hohagen, F1
Pouzet, B1
Andersen, MP1
Hogg, S1
Sievers, M1
Sato, T1
Möller, HJ1
Bottlender, R1
Friedman, JI1
Ocampo, R1
Elbaz, Z1
Parrella, M1
White, L1
Bowler, S1
Davis, KL1
Harvey, PD1
Barkan, T1
Peled, A1
Modai, I1
Rehavi, M1
Ziegenbein, M1
Kropp, S1
Hillemacher, T1
Bleich, S1
Lindberg, N1
Tani, P1
Takala, P1
Sailas, E1
Putkonen, H1
Eronen, M1
Virkkunen, M2
Padala, PR1
Sadiq, HJ1
Padala, KP1
Montross, L1
Patterson, TL1
Haukka, J1
Tiihonen, J2
Härkänen, T1
Lönnqvist, J1
Dollfus, S1
Larmurier-Montagne, A1
Razafimandimby, A1
Allio, G1
Membrey, JM1
Delcroix, N1
Etard, O1
Vartiainen, H1
Putkonen, A1
Koponen, H1
Hakola, P1
Lehto, H4
Oretti, RG1
Spurlock, G1
Buckland, PR1
McGuffin, P1
Salokangas, RK3
Saarijärvi, S3
Taiminen, T2
Kallioniemi, H1
Niemi, H3
Tuominen, J1
Ahola, V3
Syvälahti, E3
Taiminen, TJ1
Soares, JC1
Gershon, S1
Taylor, D1
Ellison, Z1
Ementon Shaw, L1
Wickham, H1
Murray, R1
Thallasinos, A1
Carroll, B1

Clinical Trials (4)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Double-blind Clinical Trial Controlled With Placebo of the Efficacy of Reboxetine and Citalopram as an Adjunct Treatment to Second Generation Antipsychotics in the Treatment of Negative Symptoms of Schizophrenia[NCT01300364]Phase 4249 participants (Anticipated)Interventional2008-11-30Recruiting
Citalopram Augmentation in Older Patients With Schizophrenia[NCT00047450]212 participants (Actual)Interventional2001-09-30Completed
Minocycline Augmentation of Clozapine for Treatment Resistant Schizophrenia: A Randomised Placebo-controlled Double-blind Trial[NCT02533232]Phase 160 participants (Anticipated)Interventional2022-08-30Recruiting
Placebo-Controlled Trial of Cipralex in the Treatment of Negative Symptoms in Schizophrenia[NCT00148447]Phase 340 participants Interventional2004-11-30Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

6 reviews available for citalopram and Schizophrenia

ArticleYear
Psychotic Disorders in the Elderly: Diagnosis, Epidemiology, and Treatment.
    The Psychiatric clinics of North America, 2022, Volume: 45, Issue:4

    Topics: Aged; Antipsychotic Agents; Citalopram; Dementia; Humans; Psychotic Disorders; Schizophrenia

2022
Psychotic Disorders in the Elderly: Diagnosis, Epidemiology, and Treatment.
    The Psychiatric clinics of North America, 2022, Volume: 45, Issue:4

    Topics: Aged; Antipsychotic Agents; Citalopram; Dementia; Humans; Psychotic Disorders; Schizophrenia

2022
Psychotic Disorders in the Elderly: Diagnosis, Epidemiology, and Treatment.
    The Psychiatric clinics of North America, 2022, Volume: 45, Issue:4

    Topics: Aged; Antipsychotic Agents; Citalopram; Dementia; Humans; Psychotic Disorders; Schizophrenia

2022
Psychotic Disorders in the Elderly: Diagnosis, Epidemiology, and Treatment.
    The Psychiatric clinics of North America, 2022, Volume: 45, Issue:4

    Topics: Aged; Antipsychotic Agents; Citalopram; Dementia; Humans; Psychotic Disorders; Schizophrenia

2022
Psychotic Disorders in the Elderly: Diagnosis, Epidemiology, and Treatment.
    The Psychiatric clinics of North America, 2022, Volume: 45, Issue:4

    Topics: Aged; Antipsychotic Agents; Citalopram; Dementia; Humans; Psychotic Disorders; Schizophrenia

2022
Psychotic Disorders in the Elderly: Diagnosis, Epidemiology, and Treatment.
    The Psychiatric clinics of North America, 2022, Volume: 45, Issue:4

    Topics: Aged; Antipsychotic Agents; Citalopram; Dementia; Humans; Psychotic Disorders; Schizophrenia

2022
Psychotic Disorders in the Elderly: Diagnosis, Epidemiology, and Treatment.
    The Psychiatric clinics of North America, 2022, Volume: 45, Issue:4

    Topics: Aged; Antipsychotic Agents; Citalopram; Dementia; Humans; Psychotic Disorders; Schizophrenia

2022
Psychotic Disorders in the Elderly: Diagnosis, Epidemiology, and Treatment.
    The Psychiatric clinics of North America, 2022, Volume: 45, Issue:4

    Topics: Aged; Antipsychotic Agents; Citalopram; Dementia; Humans; Psychotic Disorders; Schizophrenia

2022
Psychotic Disorders in the Elderly: Diagnosis, Epidemiology, and Treatment.
    The Psychiatric clinics of North America, 2022, Volume: 45, Issue:4

    Topics: Aged; Antipsychotic Agents; Citalopram; Dementia; Humans; Psychotic Disorders; Schizophrenia

2022
Selective noradrenaline reuptake inhibitors for schizophrenia.
    The Cochrane database of systematic reviews, 2018, Jan-25, Volume: 1

    Topics: Adrenergic Uptake Inhibitors; Adult; Atomoxetine Hydrochloride; Citalopram; Cognition; Humans; Morph

2018
Interventions for comorbid problem gambling and psychiatric disorders: Advancing a developing field of research.
    Addictive behaviors, 2016, Volume: 58

    Topics: Acetylcysteine; Antimanic Agents; Antipsychotic Agents; Anxiety Disorders; Behavior Therapy; Bipolar

2016
Pharmacological augmentation strategies for schizophrenia patients with insufficient response to clozapine: a quantitative literature review.
    Schizophrenia bulletin, 2012, Volume: 38, Issue:5

    Topics: Antipsychotic Agents; Brief Psychiatric Rating Scale; Citalopram; Clozapine; Dioxoles; Double-Blind

2012
[Obsessive-compulsive disorders in general practice. How the obsessive-compulsive neurotic is revealed by skin and hair].
    MMW Fortschritte der Medizin, 2003, May-26, Volume: 145 Suppl 2

    Topics: Adolescent; Adult; Anti-Anxiety Agents; Antidepressive Agents, Second-Generation; Antidepressive Age

2003
Therapeutic targets in late-life psychoses: review of concepts and critical issues.
    Schizophrenia research, 1997, Oct-30, Volume: 27, Issue:2-3

    Topics: Affective Disorders, Psychotic; Age Factors; Age of Onset; Aged; Antipsychotic Agents; Benzodiazepin

1997

Trials

23 trials available for citalopram and Schizophrenia

ArticleYear
Hippocampal Subfield Volumes Predict Disengagement from Maintenance Treatment in First Episode Schizophrenia.
    Schizophrenia bulletin, 2023, 01-03, Volume: 49, Issue:1

    Topics: China; Citalopram; Hippocampus; Humans; Magnetic Resonance Imaging; Psychotic Disorders; Schizophren

2023
Escitalopram augmentation improves negative symptoms of treatment resistant schizophrenia patients - A randomized controlled trial.
    Neuroscience letters, 2018, 08-10, Volume: 681

    Topics: Adult; Antipsychotic Agents; Citalopram; Double-Blind Method; Drug Synergism; Drug Therapy, Combinat

2018
Citalopram in first episode schizophrenia: The DECIFER trial.
    Schizophrenia research, 2019, Volume: 208

    Topics: Adolescent; Adult; Antidepressive Agents, Second-Generation; Citalopram; Depression; Female; Humans;

2019
No effects of antidepressants on negative symptoms in schizophrenia.
    Journal of clinical psychopharmacology, 2013, Volume: 33, Issue:5

    Topics: Adrenergic Uptake Inhibitors; Adult; Affect; Analysis of Variance; Antidepressive Agents; Antipsycho

2013
Double-blind, placebo-controlled study of the efficacy of reboxetine and citalopram as adjuncts to atypical antipsychotics for negative symptoms of schizophrenia.
    The Journal of clinical psychiatry, 2014, Volume: 75, Issue:6

    Topics: Adult; Antidepressive Agents; Antipsychotic Agents; Benzodiazepines; Citalopram; Depression; Double-

2014
Antidepressant Controlled Trial For Negative Symptoms In Schizophrenia (ACTIONS): a double-blind, placebo-controlled, randomised clinical trial.
    Health technology assessment (Winchester, England), 2016, Volume: 20, Issue:29

    Topics: Adult; Antidepressive Agents, Second-Generation; Antipsychotic Agents; Citalopram; Cost-Benefit Anal

2016
Citalopram augmentation for subsyndromal symptoms of depression in middle-aged and older outpatients with schizophrenia and schizoaffective disorder: a randomized controlled trial.
    The Journal of clinical psychiatry, 2009, Volume: 70, Issue:4

    Topics: Adult; Aged; Ambulatory Care; Antipsychotic Agents; Citalopram; Diagnostic and Statistical Manual of

2009
A single high dose of escitalopram increases mismatch negativity without affecting processing negativity or P300 amplitude in healthy volunteers.
    Journal of psychopharmacology (Oxford, England), 2010, Volume: 24, Issue:8

    Topics: Acoustic Stimulation; Adult; Anxiety Disorders; Blood Pressure; Citalopram; Cross-Over Studies; Doub

2010
Treatment of subsyndromal depressive symptoms in middle-aged and older adults with schizophrenia: effect on functioning.
    International journal of geriatric psychiatry, 2010, Volume: 25, Issue:2

    Topics: Aged; Analysis of Variance; Antipsychotic Agents; Citalopram; Depressive Disorder; Female; Humans; M

2010
Augmentation with citalopram for suicidal ideation in middle-aged and older outpatients with schizophrenia and schizoaffective disorder who have subthreshold depressive symptoms: a randomized controlled trial.
    The Journal of clinical psychiatry, 2010, Volume: 71, Issue:7

    Topics: Adult; Aged; Antidepressive Agents, Second-Generation; Antipsychotic Agents; Citalopram; Depression;

2010
Escitalopram in the treatment of negative symptoms in patients with chronic schizophrenia: a randomized double-blind placebo-controlled trial.
    Psychiatry research, 2010, Aug-30, Volume: 179, Issue:1

    Topics: Adult; Chronic Disease; Citalopram; Double-Blind Method; Drug Administration Schedule; Female; Human

2010
Treatment of subsyndromal depressive symptoms in middle-age and older patients with schizophrenia: effect of age on response.
    The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry, 2010, Volume: 18, Issue:9

    Topics: Age Factors; Antidepressive Agents, Second-Generation; Antipsychotic Agents; Citalopram; Depression;

2010
Narrative evolution and assimilation of problematic experiences in a case of pharmacotherapy for schizophrenia.
    Psychotherapy research : journal of the Society for Psychotherapy Research, 2011, Volume: 21, Issue:1

    Topics: Adaptation, Psychological; Antidepressive Agents, Second-Generation; Antipsychotic Agents; Awareness

2011
Does antidepressant treatment improve cognition in older people with schizophrenia or schizoaffective disorder and comorbid subsyndromal depression?
    Neuropsychobiology, 2012, Volume: 65, Issue:3

    Topics: Adult; Aging; Antidepressive Agents; Citalopram; Cognition Disorders; Comorbidity; Depression; Doubl

2012
Escitalopram in the treatment of patients with schizophrenia and obsessive-compulsive disorder: an open-label, prospective study.
    International clinical psychopharmacology, 2013, Volume: 28, Issue:2

    Topics: Adult; Antipsychotic Agents; Anxiety; Citalopram; Compulsive Behavior; Diagnostic and Statistical Ma

2013
The effect of citalopram adjunctive treatment added to atypical antipsychotic medications for cognitive performance in patients with schizophrenia.
    Journal of clinical psychopharmacology, 2005, Volume: 25, Issue:3

    Topics: Adult; Analysis of Variance; Antipsychotic Agents; Citalopram; Cognition; Cross-Over Studies; Double

2005
Subsyndromal depressive symptoms in middle-aged and older persons with schizophrenia.
    The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry, 2007, Volume: 15, Issue:12

    Topics: Age Factors; Chronic Disease; Citalopram; Comorbidity; Depression; Depressive Disorder, Major; Doubl

2007
Citalopram, a selective serotonin reuptake inhibitor, in the treatment of aggression in schizophrenia.
    Acta psychiatrica Scandinavica, 1995, Volume: 91, Issue:5

    Topics: Adolescent; Adult; Aged; Aggression; Citalopram; Double-Blind Method; Female; Humans; Male; Middle A

1995
Citalopram as an adjuvant in chronic schizophrenia: a double-blind placebo-controlled study.
    Acta psychiatrica Scandinavica, 1996, Volume: 94, Issue:3

    Topics: Adolescent; Adult; Antipsychotic Agents; Chronic Disease; Citalopram; Dose-Response Relationship, Dr

1996
Effect of smoking on neuroleptics in schizophrenia.
    Schizophrenia research, 1997, Jan-17, Volume: 23, Issue:1

    Topics: Adult; Age Factors; Aged; Antipsychotic Agents; Citalopram; Dose-Response Relationship, Drug; Double

1997
Citalopram as an adjuvant in schizophrenia: further evidence for a serotonergic dimension in schizophrenia.
    International clinical psychopharmacology, 1997, Volume: 12, Issue:1

    Topics: Adult; Chronic Disease; Citalopram; Double-Blind Method; Humans; Psychiatric Status Rating Scales; S

1997
Co-administration of citalopram and clozapine: effect on plasma clozapine levels.
    International clinical psychopharmacology, 1998, Volume: 13, Issue:1

    Topics: Adolescent; Adult; Antidepressive Agents, Second-Generation; Antipsychotic Agents; Citalopram; Cloza

1998
Citalopram augmentation of antipsychotic treatment in older schizophrenia patients.
    International journal of geriatric psychiatry, 2001, Volume: 16, Issue:12

    Topics: Aged; Antipsychotic Agents; Citalopram; Depression; Drug Therapy, Combination; Female; Humans; Male;

2001

Other Studies

17 other studies available for citalopram and Schizophrenia

ArticleYear
Effect of citalopram on hippocampal volume in first-episode schizophrenia: Structural MRI results from the DECIFER trial.
    Psychiatry research. Neuroimaging, 2021, 06-30, Volume: 312

    Topics: Antipsychotic Agents; Citalopram; Hippocampus; Humans; Magnetic Resonance Imaging; Schizophrenia

2021
Combined treatment with aripiprazole and antidepressants reversed some MK-801-induced schizophrenia-like symptoms in mice.
    Pharmacological reports : PR, 2018, Volume: 70, Issue:4

    Topics: Animals; Antidepressive Agents; Antipsychotic Agents; Aripiprazole; Citalopram; Disease Models, Anim

2018
The effectiveness of high-dose escitalopram in the treatment of patients suffering from schizophrenia with comorbid obsessive-compulsive disorder: an open-label study.
    International clinical psychopharmacology, 2019, Volume: 34, Issue:4

    Topics: Adult; Antipsychotic Agents; Citalopram; Female; Humans; Male; Middle Aged; Obsessive-Compulsive Dis

2019
Combination of escitalopram and aripiprazole causes significant improvement of negative symptoms of simple schizophrenia.
    Psychiatry and clinical neurosciences, 2014, Volume: 68, Issue:7

    Topics: Aripiprazole; Citalopram; Drug Therapy, Combination; Female; Humans; Middle Aged; Piperazines; Quino

2014
Alpha7 nicotinic acetylcholine receptor agonists and PAMs as adjunctive treatment in schizophrenia. An experimental study.
    European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology, 2016, Volume: 26, Issue:9

    Topics: alpha7 Nicotinic Acetylcholine Receptor; Animals; Antidepressive Agents; Antipsychotic Agents; Benza

2016
Effect of antidepressants on spatial memory deficit induced by dizocilpine.
    Psychiatry research, 2016, Oct-30, Volume: 244

    Topics: Animals; Antidepressive Agents; Cell Count; Citalopram; Cognition; Cognitive Dysfunction; Dizocilpin

2016
Risperidone and escitalopram co-administration: A potential treatment of schizophrenia symptoms with less side effects.
    Pharmacological reports : PR, 2017, Volume: 69, Issue:1

    Topics: Animals; Antipsychotic Agents; Citalopram; Dopamine; Drug Therapy, Combination; Male; Nucleus Accumb

2017
Drug-drug conditioning between citalopram and haloperidol or olanzapine in a conditioned avoidance response model: implications for polypharmacy in schizophrenia.
    Behavioural pharmacology, 2012, Volume: 23, Issue:7

    Topics: Animals; Antipsychotic Agents; Avoidance Learning; Benzodiazepines; Citalopram; Conditioning, Psycho

2012
Effects of acute treatment with antidepressant drugs on sensorimotor gating deficits in rats.
    Psychopharmacology, 2005, Volume: 178, Issue:1

    Topics: Adrenergic Uptake Inhibitors; Animals; Antidepressive Agents; Antipsychotic Agents; Bupropion; Cital

2005
Obsessive-compulsive disorder (OCD) with psychotic symptoms and response to treatment with SSRI.
    Pharmacopsychiatry, 2005, Volume: 38, Issue:2

    Topics: Adult; Behavior Therapy; Citalopram; Drug Administration Schedule; Female; Humans; Obsessive-Compuls

2005
Characterization of the serotonin transporter in lymphocytes and platelets of schizophrenia patients treated with atypical or typical antipsychotics compared to healthy individuals.
    European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology, 2006, Volume: 16, Issue:6

    Topics: Adult; Antipsychotic Agents; Blood Platelets; Citalopram; Female; Humans; Lymphocytes; Male; Middle

2006
Genetic predisposition to neuroleptic malignant syndrome in siblings.
    The Annals of pharmacotherapy, 2006, Volume: 40, Issue:3

    Topics: Adult; Antipsychotic Agents; Citalopram; Female; Humans; Male; Neuroleptic Malignant Syndrome; Polym

2006
Increased deep sleep in a medication-free, detoxified female offender with schizophrenia, alcoholism and a history of attempted homicide: effect of concomitant administration of quetiapine and citalopram.
    Criminal behaviour and mental health : CBMH, 2006, Volume: 16, Issue:1

    Topics: Adult; Aggression; Alcoholism; Antidepressive Agents, Second-Generation; Antipsychotic Agents; Antis

2006
Urinary obstruction with citalopram and aripiprazole combination in an elderly patient.
    Journal of clinical psychopharmacology, 2006, Volume: 26, Issue:6

    Topics: Aged; Antipsychotic Agents; Aripiprazole; Citalopram; Drug Therapy, Combination; Humans; Male; Piper

2006
Association between medication and risk of suicide, attempted suicide and death in nationwide cohort of suicidal patients with schizophrenia.
    Pharmacoepidemiology and drug safety, 2008, Volume: 17, Issue:7

    Topics: Adult; Antidepressive Agents; Antipsychotic Agents; Bayes Theorem; Benzodiazepines; Citalopram; Coho

2008
Treatment of auditory hallucinations by combining high-frequency repetitive transcranial magnetic stimulation and functional magnetic resonance imaging.
    Schizophrenia research, 2008, Volume: 102, Issue:1-3

    Topics: Antidepressive Agents; Antipsychotic Agents; Citalopram; Combined Modality Therapy; Comorbidity; Dep

2008
Lack of effect of antipsychotic and antidepressant drugs on glutamate receptor mRNA levels in rat brains.
    Neuroscience letters, 1994, Aug-15, Volume: 177, Issue:1-2

    Topics: Animals; Antidepressive Agents; Antipsychotic Agents; Base Sequence; Brain Chemistry; Citalopram; Cl

1994