citalopram has been researched along with Premenstrual Syndrome in 11 studies
Citalopram: A furancarbonitrile that is one of the serotonin uptake inhibitors used as an antidepressant. The drug is also effective in reducing ethanol uptake in alcoholics and is used in depressed patients who also suffer from TARDIVE DYSKINESIA in preference to tricyclic antidepressants, which aggravate dyskinesia.
citalopram : A racemate comprising equimolar amounts of (R)-citalopram and its enantiomer, escitalopram. It is used as an antidepressant, although only escitalopram is active.
1-[3-(dimethylamino)propyl]-1-(4-fluorophenyl)-1,3-dihydro-2-benzofuran-5-carbonitrile : A nitrile that is 1,3-dihydro-2-benzofuran-5-carbonitrile in which one of the hydrogens at position 1 is replaced by a p-fluorophenyl group, while the other is replaced by a 3-(dimethylamino)propyl group.
Premenstrual Syndrome: A combination of distressing physical, psychologic, or behavioral changes that occur during the luteal phase of the menstrual cycle. Symptoms of PMS are diverse (such as pain, water-retention, anxiety, cravings, and depression) and they diminish markedly 2 or 3 days after the initiation of menses.
| Excerpt | Relevance | Reference |
|---|---|---|
| "We have investigated the ability of citalopram, a serotonin reuptake inhibitor, to alter the functional sensitivity to a neuroactive steroid during the late luteal phase in twelve women with premenstrual syndrome." | 9.08 | Citalopram increases pregnanolone sensitivity in patients with premenstrual syndrome: an open trial. ( Bäckström, T; Sundström, I, 1998) |
| "We have investigated the ability of citalopram, a serotonin reuptake inhibitor, to alter the functional sensitivity to a neuroactive steroid during the late luteal phase in twelve women with premenstrual syndrome." | 5.08 | Citalopram increases pregnanolone sensitivity in patients with premenstrual syndrome: an open trial. ( Bäckström, T; Sundström, I, 1998) |
| "The efficacy and tolerability of symptom-onset dosing with citalopram in the treatment of premenstrual dysphoric disorder (PMDD) was evaluated in an open trial." | 2.73 | Symptom-onset dosing with citalopram in the treatment of premenstrual dysphoric disorder (PMDD): a case series. ( Ravindran, AV; Ravindran, LN; Steiner, M; Woods, SA, 2007) |
| "Escitalopram was found to exert a marked and a dose-dependent symptom-reducing effect, 20 mg/d being clearly superior to 10 mg/d." | 2.73 | Escitalopram administered in the luteal phase exerts a marked and dose-dependent effect in premenstrual dysphoric disorder. ( Ekman, A; Eriksson, E; Mattson, UB; Nissbrandt, H; Sinclair, S; Sörvik, K; Ysander, C, 2008) |
| "Escitalopram was well tolerated." | 2.71 | A preliminary study of luteal phase versus symptom-onset dosing with escitalopram for premenstrual dysphoric disorder. ( Ferdousi, T; Freeman, EW; Lin, H; Sammel, MD; Sondheimer, SJ, 2005) |
| " A placebo-controlled study of citalopram, the most selective SSRI, demonstrated that half-cycle dosing (luteal phase) was effective for DSM-IV-defined premenstrual dysphoric disorder (PMDD), a severe form of PMS." | 2.70 | Citalopram in PMS patients with prior SSRI treatment failure: a preliminary study. ( Auletto, R; Freeman, EW; Jabara, S; Sondheimer, SJ, 2002) |
| " One group (N = 17 completers) was administered citalopram continuously at a constant dosage (20+/-10 mg/day) throughout the menstrual cycle." | 2.69 | Citalopram in premenstrual dysphoria: is intermittent treatment during luteal phases more effective than continuous medication throughout the menstrual cycle? ( Andersch, B; Bengtsson, F; Dagnell, I; Eriksson, E; Sundblad, C; Wikander, I; Zylberstein, D, 1998) |
| " Intermittent dosing regimens were found to be less effective (OR 0." | 2.44 | Selective serotonin reuptake inhibitors for premenstrual syndrome and premenstrual dysphoric disorder: a meta-analysis. ( Aperi, J; Borenstein, J; Jones, JB; Karne, A; Shah, NR; Shemtov, R, 2008) |
| "Citalopram is a selective serotonin re-uptake inhibitor that has demonstrated antidepressant efficacy in numerous controlled clinical trials." | 2.41 | Citalopram: a comprehensive review. ( Pollock, BG, 2001) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (18.18) | 18.2507 |
| 2000's | 8 (72.73) | 29.6817 |
| 2010's | 1 (9.09) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Shchepotin, IB | 1 |
| Zotov, AS | 1 |
| Dobzhenko, MN | 1 |
| Freeman, EW | 2 |
| Jabara, S | 1 |
| Sondheimer, SJ | 2 |
| Auletto, R | 1 |
| Aboujaoude, E | 1 |
| Gamel, N | 1 |
| Koran, LM | 1 |
| Sammel, MD | 1 |
| Ferdousi, T | 1 |
| Lin, H | 1 |
| Ravindran, LN | 1 |
| Woods, SA | 1 |
| Steiner, M | 1 |
| Ravindran, AV | 1 |
| Eriksson, E | 3 |
| Ekman, A | 1 |
| Sinclair, S | 1 |
| Sörvik, K | 1 |
| Ysander, C | 1 |
| Mattson, UB | 1 |
| Nissbrandt, H | 1 |
| Shah, NR | 1 |
| Jones, JB | 1 |
| Aperi, J | 1 |
| Shemtov, R | 1 |
| Karne, A | 1 |
| Borenstein, J | 1 |
| Sundström, I | 1 |
| Bäckström, T | 1 |
| Wikander, I | 1 |
| Sundblad, C | 2 |
| Andersch, B | 2 |
| Dagnell, I | 1 |
| Zylberstein, D | 1 |
| Bengtsson, F | 1 |
| Pollock, BG | 1 |
| Ho, HP | 1 |
| Landén, M | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Study to Determine Steady-state Level of Citalopram Pharmacokinetic Parameters in Patients With Short Bowel Syndrome[NCT00876226] | 0 participants (Actual) | Interventional | 2010-05-01 | Withdrawn | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
4 reviews available for citalopram and Premenstrual Syndrome
| Article | Year |
|---|---|
[Selective serotonin reuptake inhibitors and mammary pathologies].
Topics: Antidepressive Agents; Breast Neoplasms; Citalopram; Clinical Trials as Topic; Female; Fluoxetine; F | 2010 |
Selective serotonin reuptake inhibitors for premenstrual syndrome and premenstrual dysphoric disorder: a meta-analysis.
Topics: Adult; Citalopram; Female; Fluoxetine; Fluvoxamine; Humans; Odds Ratio; Paroxetine; Premenstrual Syn | 2008 |
Citalopram: a comprehensive review.
Topics: Alcoholism; Antidepressive Agents, Second-Generation; Anxiety Disorders; Citalopram; Clinical Trials | 2001 |
[Serotonin uptake inhibitors provide rapid relief from premenstrual dysphoria. New findings shed light on how serotonin modulates sex hormone-related behavior].
Topics: Adult; Behavior; Citalopram; Female; Gonadal Steroid Hormones; Humans; Premenstrual Syndrome; Recept | 2001 |
6 trials available for citalopram and Premenstrual Syndrome
| Article | Year |
|---|---|
Citalopram in PMS patients with prior SSRI treatment failure: a preliminary study.
Topics: Adolescent; Adult; Citalopram; Dose-Response Relationship, Drug; Drug Administration Schedule; Femal | 2002 |
A preliminary study of luteal phase versus symptom-onset dosing with escitalopram for premenstrual dysphoric disorder.
Topics: Adult; Citalopram; Double-Blind Method; Drug Administration Schedule; Female; Humans; Luteal Phase; | 2005 |
Symptom-onset dosing with citalopram in the treatment of premenstrual dysphoric disorder (PMDD): a case series.
Topics: Adult; Antidepressive Agents, Second-Generation; Citalopram; Dose-Response Relationship, Drug; Drug | 2007 |
Escitalopram administered in the luteal phase exerts a marked and dose-dependent effect in premenstrual dysphoric disorder.
Topics: Adult; Capsules; Citalopram; Diagnostic and Statistical Manual of Mental Disorders; Dose-Response Re | 2008 |
Citalopram increases pregnanolone sensitivity in patients with premenstrual syndrome: an open trial.
Topics: Adult; Affect; Citalopram; Depression; Eye Movements; Female; Humans; Libido; Middle Aged; Pregnanol | 1998 |
Citalopram in premenstrual dysphoria: is intermittent treatment during luteal phases more effective than continuous medication throughout the menstrual cycle?
Topics: Adult; Antidepressive Agents, Second-Generation; Citalopram; Depression; Dose-Response Relationship, | 1998 |
1 other study available for citalopram and Premenstrual Syndrome
| Article | Year |
|---|---|
A case of kleptomania correlating with premenstrual dysphoria.
Topics: Citalopram; Disruptive, Impulse Control, and Conduct Disorders; Female; Humans; Luteal Phase; Menstr | 2004 |