citalopram has been researched along with Kidney Failure in 4 studies
Citalopram: A furancarbonitrile that is one of the serotonin uptake inhibitors used as an antidepressant. The drug is also effective in reducing ethanol uptake in alcoholics and is used in depressed patients who also suffer from TARDIVE DYSKINESIA in preference to tricyclic antidepressants, which aggravate dyskinesia.
citalopram : A racemate comprising equimolar amounts of (R)-citalopram and its enantiomer, escitalopram. It is used as an antidepressant, although only escitalopram is active.
1-[3-(dimethylamino)propyl]-1-(4-fluorophenyl)-1,3-dihydro-2-benzofuran-5-carbonitrile : A nitrile that is 1,3-dihydro-2-benzofuran-5-carbonitrile in which one of the hydrogens at position 1 is replaced by a p-fluorophenyl group, while the other is replaced by a 3-(dimethylamino)propyl group.
Kidney Failure: A severe irreversible decline in the ability of kidneys to remove wastes, concentrate URINE, and maintain ELECTROLYTE BALANCE; BLOOD PRESSURE; and CALCIUM metabolism.
| Excerpt | Relevance | Reference |
|---|---|---|
| "To compare the pharmacokinetics of the antidepressant citalopram and its metabolites demethylcitalopram and didemethylcitalopram in subjects with moderate renal insufficiency and subjects with hepatic cirrhosis with that in healthy subjects." | 9.08 | Single-dose pharmacokinetics of citalopram in patients with moderate renal insufficiency or hepatic cirrhosis compared with healthy subjects. ( Aaes-Jørgensen, T; Joffe, P; Larsen, FS; Pedersen, V; Ring-Larsen, H; Sidhu, J, 1998) |
| "Citalopram has been associated with seizures, ECG abnormalities, rhabdomyolysis and coma after overdose." | 5.32 | Adult respiratory distress syndrome and renal failure associated with citalopram overdose. ( Bateman, DN; Flanagan, RJ; Kelly, CA; Spencer, EP; Upex, A, 2003) |
| "To compare the pharmacokinetics of the antidepressant citalopram and its metabolites demethylcitalopram and didemethylcitalopram in subjects with moderate renal insufficiency and subjects with hepatic cirrhosis with that in healthy subjects." | 5.08 | Single-dose pharmacokinetics of citalopram in patients with moderate renal insufficiency or hepatic cirrhosis compared with healthy subjects. ( Aaes-Jørgensen, T; Joffe, P; Larsen, FS; Pedersen, V; Ring-Larsen, H; Sidhu, J, 1998) |
| "Escitalopram has low protein binding (56%) and is not likely to cause interactions with highly protein-bound drugs." | 2.44 | The clinical pharmacokinetics of escitalopram. ( Rao, N, 2007) |
| "Citalopram has been associated with seizures, ECG abnormalities, rhabdomyolysis and coma after overdose." | 1.32 | Adult respiratory distress syndrome and renal failure associated with citalopram overdose. ( Bateman, DN; Flanagan, RJ; Kelly, CA; Spencer, EP; Upex, A, 2003) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (25.00) | 18.2507 |
| 2000's | 2 (50.00) | 29.6817 |
| 2010's | 1 (25.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Labos, C | 1 |
| Dasgupta, K | 1 |
| Nedjar, H | 1 |
| Turecki, G | 1 |
| Rahme, E | 1 |
| Kelly, CA | 1 |
| Upex, A | 1 |
| Spencer, EP | 1 |
| Flanagan, RJ | 1 |
| Bateman, DN | 1 |
| Rao, N | 1 |
| Joffe, P | 1 |
| Larsen, FS | 1 |
| Pedersen, V | 1 |
| Ring-Larsen, H | 1 |
| Aaes-Jørgensen, T | 1 |
| Sidhu, J | 1 |
1 review available for citalopram and Kidney Failure
| Article | Year |
|---|---|
The clinical pharmacokinetics of escitalopram.
Topics: Adolescent; Adult; Age Factors; Aged; Anxiety Disorders; Child; Citalopram; Depression; Drug Interac | 2007 |
1 trial available for citalopram and Kidney Failure
| Article | Year |
|---|---|
Single-dose pharmacokinetics of citalopram in patients with moderate renal insufficiency or hepatic cirrhosis compared with healthy subjects.
Topics: Administration, Oral; Adolescent; Adult; Biological Availability; Citalopram; Female; Humans; Inject | 1998 |
2 other studies available for citalopram and Kidney Failure
| Article | Year |
|---|---|
Risk of bleeding associated with combined use of selective serotonin reuptake inhibitors and antiplatelet therapy following acute myocardial infarction.
Topics: Adrenal Cortex Hormones; Age Factors; Aged; Anemia; Angioplasty; Anticoagulants; Antihypertensive Ag | 2011 |
Adult respiratory distress syndrome and renal failure associated with citalopram overdose.
Topics: Citalopram; Drug Overdose; Humans; Male; Middle Aged; Poisoning; Renal Insufficiency; Respiratory Di | 2003 |