citalopram has been researched along with Insulin Resistance in 6 studies
Citalopram: A furancarbonitrile that is one of the serotonin uptake inhibitors used as an antidepressant. The drug is also effective in reducing ethanol uptake in alcoholics and is used in depressed patients who also suffer from TARDIVE DYSKINESIA in preference to tricyclic antidepressants, which aggravate dyskinesia.
citalopram : A racemate comprising equimolar amounts of (R)-citalopram and its enantiomer, escitalopram. It is used as an antidepressant, although only escitalopram is active.
1-[3-(dimethylamino)propyl]-1-(4-fluorophenyl)-1,3-dihydro-2-benzofuran-5-carbonitrile : A nitrile that is 1,3-dihydro-2-benzofuran-5-carbonitrile in which one of the hydrogens at position 1 is replaced by a p-fluorophenyl group, while the other is replaced by a 3-(dimethylamino)propyl group.
Insulin Resistance: Diminished effectiveness of INSULIN in lowering blood sugar levels: requiring the use of 200 units or more of insulin per day to prevent HYPERGLYCEMIA or KETOSIS.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Our second aim was to investigate the effects of escitalopram vs placebo in LBW men in the LHPA axis and insulin sensitivity (part 2)." | 9.27 | Escitalopram Ameliorates Hypercortisolemia and Insulin Resistance in Low Birth Weight Men With Limbic Brain Alterations. ( Buhl, CS; Buhl, ES; Lund, S; Møller, N; Stødkilde-Jørgensen, H; Vaag, A; Videbech, P, 2018) |
| " Enhanced cortisol synthesis, impaired leptin production and diminished insulin sensitivity have been reported in some depressed populations." | 9.11 | Impact of the selective serotonin reuptake inhibitor citalopram on insulin sensitivity, leptin and basal cortisol secretion in depressed and non-depressed euglycemic women of reproductive age. ( Baldock, SD; Castracane, VD; Kauffman, RP; Owens, R; White, DL, 2005) |
| " Recent findings have shown, that adipocytokines leptin and adiponectin might play a role in both depression and MetS." | 7.75 | Leptin, adiponectin, leptin to adiponectin ratio and insulin resistance in depressive women. ( Jachymova, M; Jirak, R; Tvrzicka, E; Vecka, M; Zak, A; Zeman, M, 2009) |
| " Our second aim was to investigate the effects of escitalopram vs placebo in LBW men in the LHPA axis and insulin sensitivity (part 2)." | 5.27 | Escitalopram Ameliorates Hypercortisolemia and Insulin Resistance in Low Birth Weight Men With Limbic Brain Alterations. ( Buhl, CS; Buhl, ES; Lund, S; Møller, N; Stødkilde-Jørgensen, H; Vaag, A; Videbech, P, 2018) |
| " Enhanced cortisol synthesis, impaired leptin production and diminished insulin sensitivity have been reported in some depressed populations." | 5.11 | Impact of the selective serotonin reuptake inhibitor citalopram on insulin sensitivity, leptin and basal cortisol secretion in depressed and non-depressed euglycemic women of reproductive age. ( Baldock, SD; Castracane, VD; Kauffman, RP; Owens, R; White, DL, 2005) |
| " We examined whether treatment with a selective serotonin reuptake inhibitor [escitalopram (ESC)] could downregulate HPA axis activity and restore insulin sensitivity in LBW rats." | 3.76 | Treatment with an SSRI antidepressant restores hippocampo-hypothalamic corticosteroid feedback and reverses insulin resistance in low-birth-weight rats. ( Buhl, CS; Buhl, ES; Elfving, B; Jensen, TK; Jessen, N; Kristiansen, SB; Lund, S; Petersen, KF; Pold, R; Schmitz, O; Solskov, L; Wegener, G, 2010) |
| " Recent findings have shown, that adipocytokines leptin and adiponectin might play a role in both depression and MetS." | 3.75 | Leptin, adiponectin, leptin to adiponectin ratio and insulin resistance in depressive women. ( Jachymova, M; Jirak, R; Tvrzicka, E; Vecka, M; Zak, A; Zeman, M, 2009) |
| "Insulin resistance was estimated by homeostasis model assessment." | 1.33 | The metabolic syndrome is associated with reduced central serotonergic responsivity in healthy community volunteers. ( Flory, JD; Korytkowski, MT; Mackey, RH; Manuck, SB; Muldoon, MF; Pollock, BG, 2006) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 3 (50.00) | 29.6817 |
| 2010's | 3 (50.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Buhl, CS | 2 |
| Stødkilde-Jørgensen, H | 1 |
| Videbech, P | 1 |
| Vaag, A | 1 |
| Møller, N | 1 |
| Lund, S | 2 |
| Buhl, ES | 2 |
| Zeman, M | 1 |
| Jirak, R | 1 |
| Jachymova, M | 1 |
| Vecka, M | 1 |
| Tvrzicka, E | 1 |
| Zak, A | 1 |
| Jensen, TK | 1 |
| Jessen, N | 1 |
| Elfving, B | 1 |
| Kristiansen, SB | 1 |
| Pold, R | 1 |
| Solskov, L | 1 |
| Schmitz, O | 1 |
| Wegener, G | 1 |
| Petersen, KF | 1 |
| Sondermeijer, BM | 1 |
| Klein Twennaar, CF | 1 |
| Kastelein, JJ | 1 |
| Franssen, EJ | 1 |
| Hutten, BA | 1 |
| Dallinga-Thie, GM | 1 |
| Stroes, ES | 1 |
| Fliers, E | 1 |
| Twickler, MT | 1 |
| Serlie, MJ | 1 |
| Muldoon, MF | 1 |
| Mackey, RH | 1 |
| Korytkowski, MT | 1 |
| Flory, JD | 1 |
| Pollock, BG | 1 |
| Manuck, SB | 1 |
| Kauffman, RP | 1 |
| Castracane, VD | 1 |
| White, DL | 1 |
| Baldock, SD | 1 |
| Owens, R | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Effects of 3 Months of SSRI-Treatment on Metabolism and HPA-axis in Young Men Born With Low Birth Weight - a Randomized, Double Blinded and Placebo-controlled Trial[NCT00971815] | 60 participants (Actual) | Interventional | 2009-05-31 | Completed | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
3 trials available for citalopram and Insulin Resistance
| Article | Year |
|---|---|
Escitalopram Ameliorates Hypercortisolemia and Insulin Resistance in Low Birth Weight Men With Limbic Brain Alterations.
Topics: Adult; Blood Glucose; Brain Diseases; Case-Control Studies; Citalopram; Cushing Syndrome; Double-Bli | 2018 |
Infusion of a lipid emulsion in healthy men decreases the serotonergic response.
Topics: Adolescent; Adult; Citalopram; Down-Regulation; Fat Emulsions, Intravenous; Fatty Acids, Nonesterifi | 2012 |
Impact of the selective serotonin reuptake inhibitor citalopram on insulin sensitivity, leptin and basal cortisol secretion in depressed and non-depressed euglycemic women of reproductive age.
Topics: Administration, Oral; Adolescent; Adult; Citalopram; Cohort Studies; Depressive Disorder; Drug Admin | 2005 |
3 other studies available for citalopram and Insulin Resistance
| Article | Year |
|---|---|
Leptin, adiponectin, leptin to adiponectin ratio and insulin resistance in depressive women.
Topics: Adiponectin; Adult; Aged; Antidepressive Agents; Blood Glucose; Body Mass Index; Chi-Square Distribu | 2009 |
Treatment with an SSRI antidepressant restores hippocampo-hypothalamic corticosteroid feedback and reverses insulin resistance in low-birth-weight rats.
Topics: Adrenocorticotropic Hormone; Analysis of Variance; Animals; Area Under Curve; Blood Glucose; Body We | 2010 |
The metabolic syndrome is associated with reduced central serotonergic responsivity in healthy community volunteers.
Topics: Adult; Area Under Curve; Brain; Citalopram; Cross-Sectional Studies; Female; Humans; Insulin Resista | 2006 |