citalopram has been researched along with Infarction, Middle Cerebral Artery in 4 studies
Citalopram: A furancarbonitrile that is one of the serotonin uptake inhibitors used as an antidepressant. The drug is also effective in reducing ethanol uptake in alcoholics and is used in depressed patients who also suffer from TARDIVE DYSKINESIA in preference to tricyclic antidepressants, which aggravate dyskinesia.
citalopram : A racemate comprising equimolar amounts of (R)-citalopram and its enantiomer, escitalopram. It is used as an antidepressant, although only escitalopram is active.
1-[3-(dimethylamino)propyl]-1-(4-fluorophenyl)-1,3-dihydro-2-benzofuran-5-carbonitrile : A nitrile that is 1,3-dihydro-2-benzofuran-5-carbonitrile in which one of the hydrogens at position 1 is replaced by a p-fluorophenyl group, while the other is replaced by a 3-(dimethylamino)propyl group.
Infarction, Middle Cerebral Artery: NECROSIS occurring in the MIDDLE CEREBRAL ARTERY distribution system which brings blood to the entire lateral aspects of each CEREBRAL HEMISPHERE. Clinical signs include impaired cognition; APHASIA; AGRAPHIA; weak and numbness in the face and arms, contralaterally or bilaterally depending on the infarction.
| Excerpt | Relevance | Reference |
|---|---|---|
| "We investigated the hypothesis that hippocampal neurogenesis related to Notch1 signaling could be a valid index for a combined citalopram and WAY100635 pharmacotherapy for the treatment of depression arising after stroke." | 7.76 | Notch1 signaling related hippocampal neurogenesis in adult poststroke depression rats: a valid index for an efficient combined citalopram and WAY100635 pharmacotherapy. ( Guo, YJ; Sui, YX; Sun, Y; Wang, SH; Zhang, ZJ, 2010) |
| "We investigated the hypothesis that hippocampal neurogenesis related to Notch1 signaling could be a valid index for a combined citalopram and WAY100635 pharmacotherapy for the treatment of depression arising after stroke." | 3.76 | Notch1 signaling related hippocampal neurogenesis in adult poststroke depression rats: a valid index for an efficient combined citalopram and WAY100635 pharmacotherapy. ( Guo, YJ; Sui, YX; Sun, Y; Wang, SH; Zhang, ZJ, 2010) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (25.00) | 29.6817 |
| 2010's | 3 (75.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Gupta, S | 1 |
| Upadhayay, D | 1 |
| Sharma, U | 1 |
| Jagannathan, NR | 1 |
| Gupta, YK | 1 |
| Wang, SH | 2 |
| Zhang, ZJ | 2 |
| Guo, YJ | 2 |
| Sui, YX | 1 |
| Sun, Y | 1 |
| Kronenberg, G | 1 |
| Balkaya, M | 1 |
| Prinz, V | 1 |
| Gertz, K | 1 |
| Ji, S | 1 |
| Kirste, I | 1 |
| Heuser, I | 1 |
| Kampmann, B | 1 |
| Hellmann-Regen, J | 1 |
| Gass, P | 1 |
| Sohr, R | 1 |
| Hellweg, R | 1 |
| Waeber, C | 1 |
| Juckel, G | 1 |
| Hörtnagl, H | 1 |
| Stumm, R | 1 |
| Endres, M | 1 |
| Teng, GJ | 1 |
| Chen, BA | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Clinical Study Evaluating the Efficacy of Nitazoxanide and Escitalopram as Adjuvant Therapies in Patients With Rheumatoid Arthritis[NCT05480878] | Phase 3 | 90 participants (Actual) | Interventional | 2022-12-02 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
4 other studies available for citalopram and Infarction, Middle Cerebral Artery
| Article | Year |
|---|---|
Citalopram attenuated neurobehavioral, biochemical, and metabolic alterations in transient middle cerebral artery occlusion model of stroke in male Wistar rats.
Topics: Animals; Brain; Brain Ischemia; Citalopram; Glutathione; Infarction, Middle Cerebral Artery; Male; M | 2018 |
Notch1 signaling related hippocampal neurogenesis in adult poststroke depression rats: a valid index for an efficient combined citalopram and WAY100635 pharmacotherapy.
Topics: Animals; Behavior, Animal; Citalopram; Depression; Disease Models, Animal; Drug Evaluation, Preclini | 2010 |
Exofocal dopaminergic degeneration as antidepressant target in mouse model of poststroke depression.
Topics: Animals; Brain-Derived Neurotrophic Factor; Citalopram; Corticosterone; Depression; Disease Models, | 2012 |
Hippocampal neurogenesis and behavioural studies on adult ischemic rat response to chronic mild stress.
Topics: Adaptation, Physiological; Adaptation, Psychological; Animals; Antidepressive Agents, Second-Generat | 2008 |