citalopram has been researched along with Inadequate Sleep in 15 studies
Citalopram: A furancarbonitrile that is one of the serotonin uptake inhibitors used as an antidepressant. The drug is also effective in reducing ethanol uptake in alcoholics and is used in depressed patients who also suffer from TARDIVE DYSKINESIA in preference to tricyclic antidepressants, which aggravate dyskinesia.
citalopram : A racemate comprising equimolar amounts of (R)-citalopram and its enantiomer, escitalopram. It is used as an antidepressant, although only escitalopram is active.
1-[3-(dimethylamino)propyl]-1-(4-fluorophenyl)-1,3-dihydro-2-benzofuran-5-carbonitrile : A nitrile that is 1,3-dihydro-2-benzofuran-5-carbonitrile in which one of the hydrogens at position 1 is replaced by a p-fluorophenyl group, while the other is replaced by a 3-(dimethylamino)propyl group.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Treatment with citalopram (5 and 10 mg/kg, ip) and desipramine (10 and 20 mg/kg, ip) for 5 days significantly improved locomotor activity, anti-anxiety like behavior in all paradigms tasks (mirror chamber, plus maze, zero maze) as compared to control (72 hr sleep-deprived)." | 5.35 | Possible role of citalopram and desipramine against sleep deprivation-induced anxiety like-behavior alterations and oxidative damage in mice. ( Garg, R; Kumar, A, 2008) |
| "This study was done to evaluate the effect of co-treatment of orexin agents along with citalopram on the modulation of depression-like behavior and the expression of BDNF in the prefrontal cortex (PFC) of sleep-deprived male mice." | 4.12 | Synergistic antidepressant effects of citalopram and SB-334867 in the REM sleep-deprived mice: Possible role of BDNF. ( Alibeik, H; Bananej, M; Khakpai, F; Saadati, N; Zarrindast, MR, 2022) |
| "Our results revealed that REM sleep deprivation reduced the percentage of open arm time (%OAT) and the percentage of the open arm entries (%OAE) but not closed arm entries (locomotor activity) in the EPM test, presenting an anxiogenic response ( P < 0." | 1.72 | The effects of citalopram, SB-334867 and orexin-1, alone or in various combinations, on the anxiogenic-like effects of REM sleep deprivation in male mice. ( Alibeik, H; Bananej, M; Khakpai, F; Saadati, N; Zarrindast, MR, 2022) |
| "Rapid eye movement (REM) sleep deprivation (SD) decreases cerebral sigma-1 receptor expression and causes cognitive deficits." | 1.42 | Cutamesine Overcomes REM Sleep Deprivation-Induced Memory Loss: Relationship to Sigma-1 Receptor Occupancy. ( Dierckx, RA; Elsinga, PH; Ishiwata, K; Luurtsema, G; Nyakas, CJ; Ramakrishnan, NK; Schepers, M; van Waarde, A, 2015) |
| " The selective serotonin reuptake inhibitor (SSRI) antidepressants reduce REM sleep time and increase REM latency after acute dosing in normal condition and even during REM rebound following RD." | 1.40 | Chronic escitalopram treatment attenuated the accelerated rapid eye movement sleep transitions after selective rapid eye movement sleep deprivation: a model-based analysis using Markov chains. ( Bagdy, G; Gyertyán, I; Kátai, Z; Kitka, T; Kostyalik, D; Tóthfalusi, L; Vas, S, 2014) |
| "Hence, REM sleep deprivation impairs memory processes." | 1.39 | The acute inhibition of rapid eye movement sleep by citalopram may impair spatial learning and passive avoidance in mice. ( Bordet, R; Bridoux, A; Derambure, P; Laloux, C; Monaca Charley, C, 2013) |
| "Treatment with citalopram (5 and 10 mg/kg, ip) and desipramine (10 and 20 mg/kg, ip) for 5 days significantly improved locomotor activity, anti-anxiety like behavior in all paradigms tasks (mirror chamber, plus maze, zero maze) as compared to control (72 hr sleep-deprived)." | 1.35 | Possible role of citalopram and desipramine against sleep deprivation-induced anxiety like-behavior alterations and oxidative damage in mice. ( Garg, R; Kumar, A, 2008) |
| "These observations suggest that REM sleep deprivation renders serotoninergic DRN neurons less sensitive to the inhibitory effect of 5-HT reuptake blockers, probably because of functional desensitization of somatodendritic 5-HT1A autoreceptors, like that previously reported after chronic treatment with several antidepressants." | 1.29 | Reduced inhibitory potency of serotonin reuptake blockers on central serotoninergic neurons in rats selectively deprived of rapid eye movement sleep. ( Adrien, J; Chastanet, M; Hamon, M; Jolas, T; Maudhuit, C, 1996) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (6.67) | 18.7374 |
| 1990's | 3 (20.00) | 18.2507 |
| 2000's | 3 (20.00) | 29.6817 |
| 2010's | 5 (33.33) | 24.3611 |
| 2020's | 3 (20.00) | 2.80 |
| Authors | Studies |
|---|---|
| Saadati, N | 2 |
| Bananej, M | 2 |
| Khakpai, F | 2 |
| Zarrindast, MR | 2 |
| Alibeik, H | 2 |
| Misrani, A | 2 |
| Tabassum, S | 2 |
| Wang, M | 1 |
| Chen, J | 1 |
| Yang, L | 2 |
| Long, C | 2 |
| Chen, X | 1 |
| Tan, SY | 1 |
| Wang, JC | 1 |
| Kátai, Z | 2 |
| Adori, C | 1 |
| Kitka, T | 2 |
| Vas, S | 2 |
| Kalmár, L | 1 |
| Kostyalik, D | 2 |
| Tóthfalusi, L | 2 |
| Palkovits, M | 1 |
| Bagdy, G | 2 |
| Gyertyán, I | 1 |
| Ramakrishnan, NK | 1 |
| Schepers, M | 1 |
| Luurtsema, G | 1 |
| Nyakas, CJ | 1 |
| Elsinga, PH | 1 |
| Ishiwata, K | 1 |
| Dierckx, RA | 1 |
| van Waarde, A | 1 |
| Garg, R | 1 |
| Kumar, A | 1 |
| Bridoux, A | 1 |
| Laloux, C | 1 |
| Derambure, P | 1 |
| Bordet, R | 1 |
| Monaca Charley, C | 1 |
| Mulert, C | 1 |
| Juckel, G | 1 |
| Brunnmeier, M | 1 |
| Karch, S | 1 |
| Leicht, G | 1 |
| Mergl, R | 1 |
| Möller, HJ | 1 |
| Hegerl, U | 1 |
| Pogarell, O | 1 |
| Frau, R | 1 |
| Orrù, M | 1 |
| Puligheddu, M | 1 |
| Gessa, GL | 1 |
| Mereu, G | 1 |
| Marrosu, F | 1 |
| Bortolato, M | 1 |
| Maudhuit, C | 3 |
| Hamon, M | 3 |
| Adrien, J | 3 |
| Jolas, T | 1 |
| Chastanet, M | 1 |
| Prévot, E | 1 |
| Le Poul, E | 1 |
| Aalto, J | 1 |
| Kiianmaa, K | 1 |
15 other studies available for citalopram and Inadequate Sleep
| Article | Year |
|---|---|
Synergistic antidepressant effects of citalopram and SB-334867 in the REM sleep-deprived mice: Possible role of BDNF.
Topics: Animals; Antidepressive Agents; Benzoxazoles; Brain-Derived Neurotrophic Factor; Citalopram; Depress | 2022 |
The effects of citalopram, SB-334867 and orexin-1, alone or in various combinations, on the anxiogenic-like effects of REM sleep deprivation in male mice.
Topics: Animals; Anti-Anxiety Agents; Anxiety; Citalopram; Male; Maze Learning; Mice; Orexin Receptor Antago | 2022 |
Citalopram prevents sleep-deprivation-induced reduction in CaMKII-CREB-BDNF signaling in mouse prefrontal cortex.
Topics: Animals; Antidepressive Agents, Second-Generation; Brain-Derived Neurotrophic Factor; Calcium-Calmod | 2020 |
Differential effects of citalopram on sleep-deprivation-induced depressive-like behavior and memory impairments in mice.
Topics: Animals; Antidepressive Agents, Second-Generation; Citalopram; CREB-Binding Protein; Depression; Dis | 2019 |
Acute escitalopram treatment inhibits REM sleep rebound and activation of MCH-expressing neurons in the lateral hypothalamus after long term selective REM sleep deprivation.
Topics: Animals; Citalopram; Electroencephalography; Hypothalamic Hormones; Hypothalamus; Male; Melanins; Ne | 2013 |
Chronic escitalopram treatment attenuated the accelerated rapid eye movement sleep transitions after selective rapid eye movement sleep deprivation: a model-based analysis using Markov chains.
Topics: Animals; Brain; Catheters, Indwelling; Citalopram; Electrodes, Implanted; Electroencephalography; Ma | 2014 |
Cutamesine Overcomes REM Sleep Deprivation-Induced Memory Loss: Relationship to Sigma-1 Receptor Occupancy.
Topics: Animals; Brain; Chromatography, High Pressure Liquid; Citalopram; Cognition; Male; Mass Spectrometry | 2015 |
Possible role of citalopram and desipramine against sleep deprivation-induced anxiety like-behavior alterations and oxidative damage in mice.
Topics: Adrenergic Uptake Inhibitors; Animals; Anxiety; Behavior, Animal; Brain; Citalopram; Desipramine; Ma | 2008 |
The acute inhibition of rapid eye movement sleep by citalopram may impair spatial learning and passive avoidance in mice.
Topics: Animals; Avoidance Learning; Citalopram; Male; Maze Learning; Memory; Mice; Mice, Inbred C57BL; Poly | 2013 |
Prediction of treatment response in major depression: integration of concepts.
Topics: Antidepressive Agents; Citalopram; Depressive Disorder, Major; Electroencephalography; Equipment Des | 2007 |
Sleep deprivation disrupts prepulse inhibition of the startle reflex: reversal by antipsychotic drugs.
Topics: Acoustic Stimulation; Animals; Antipsychotic Agents; Citalopram; Data Interpretation, Statistical; D | 2008 |
Effects of chronic treatment with zimelidine and REM sleep deprivation on the regulation of raphe neuronal activity in a rat model of depression.
Topics: Animals; Citalopram; Clomipramine; Depression; Dose-Response Relationship, Drug; Electrophysiology; | 1996 |
Reduced inhibitory potency of serotonin reuptake blockers on central serotoninergic neurons in rats selectively deprived of rapid eye movement sleep.
Topics: Animals; Citalopram; Male; Neurons; Propanolamines; Raphe Nuclei; Rats; Rats, Sprague-Dawley; Select | 1996 |
Sleep deprivation reduces the citalopram-induced inhibition of serotoninergic neuronal firing in the nucleus raphe dorsalis of the rat.
Topics: Animals; Citalopram; Corticosterone; Male; Raphe Nuclei; Rats; Rats, Wistar; Selective Serotonin Reu | 1996 |
Role of brain monoaminergic systems in the increased ethanol drinking caused by REM-sleep deprivation.
Topics: 3,4-Dihydroxyphenylacetic Acid; Alcohol Drinking; Animals; Brain Chemistry; Catecholamines; Citalopr | 1987 |