Page last updated: 2024-10-25

citalopram and Hyponatremia

citalopram has been researched along with Hyponatremia in 32 studies

Citalopram: A furancarbonitrile that is one of the serotonin uptake inhibitors used as an antidepressant. The drug is also effective in reducing ethanol uptake in alcoholics and is used in depressed patients who also suffer from TARDIVE DYSKINESIA in preference to tricyclic antidepressants, which aggravate dyskinesia.
citalopram : A racemate comprising equimolar amounts of (R)-citalopram and its enantiomer, escitalopram. It is used as an antidepressant, although only escitalopram is active.
1-[3-(dimethylamino)propyl]-1-(4-fluorophenyl)-1,3-dihydro-2-benzofuran-5-carbonitrile : A nitrile that is 1,3-dihydro-2-benzofuran-5-carbonitrile in which one of the hydrogens at position 1 is replaced by a p-fluorophenyl group, while the other is replaced by a 3-(dimethylamino)propyl group.

Hyponatremia: Deficiency of sodium in the blood; salt depletion. (Dorland, 27th ed)

Research Excerpts

ExcerptRelevanceReference
" This report describes a patient with PDD who developed deep venous thrombosis (DVT) and hyponatremia after initiating citalopram treatment."8.31Deep venous thrombosis and hyponatremia associated with citalopram use for behavioral symptoms in Parkinson's disease: a case report. ( Albalawi, A, 2023)
" We report the development of severe hyponatremia leading to adverse clinical effects due to escitalopram and thiazide diuretic use concomitantly in a patient with depression after emergency coronary artery bypass grafting."7.83Hyponatremia Due to Escitalopram and Thiazide Use After Cardiac Surgery. ( Aksoy, E; Çağlı, K; Diken, Aİ; Doğan, İ; Erçen Diken, Ö; Yalçınkaya, A; Yılmaz, S, 2016)
"Depression is a common problem in elderly patients and frequently is treated with antidepressants."5.33Recurrent hyponatremia associated with citalopram and mirtazapine. ( Akcay, A; Bavbek, N; Kargili, A; Kaya, A, 2006)
"Citalopram was discontinued and fluid restriction was instituted."5.32Severe symptomatic hyponatremia during citalopram therapy--a case report. ( Cobos-Ayala, C; Flores, G; Perez-Patrigeon, S; Vergara, J, 2004)
" This report describes a patient with PDD who developed deep venous thrombosis (DVT) and hyponatremia after initiating citalopram treatment."4.31Deep venous thrombosis and hyponatremia associated with citalopram use for behavioral symptoms in Parkinson's disease: a case report. ( Albalawi, A, 2023)
" CASE REPORT An 88-year-old woman with a history of asymptomatic chronic hyponatremia presented to our facility with symptomatic acute-on-chronic hyponatremia after she started using naproxen in addition to her daily citalopram."3.96Syndrome of Inappropriate Antidiuretic Hormone (SIADH) Induced by Long-Term Use of Citalopram and Short-Term Use of Naproxen. ( Azhar Munir, R; Chiu, CY; Khalid, A; Khanna, R; Sarwal, A; Widjaja, M, 2020)
" We report the development of severe hyponatremia leading to adverse clinical effects due to escitalopram and thiazide diuretic use concomitantly in a patient with depression after emergency coronary artery bypass grafting."3.83Hyponatremia Due to Escitalopram and Thiazide Use After Cardiac Surgery. ( Aksoy, E; Çağlı, K; Diken, Aİ; Doğan, İ; Erçen Diken, Ö; Yalçınkaya, A; Yılmaz, S, 2016)
"All antidepressants except mianserin are associated with hyponatremia."3.83Antidepressants and the risk of hyponatremia: a Danish register-based population study. ( Andersen, SE; Gislasson, G; Hansen, AH; Holm, EA; Leth-Møller, KB; Torp-Pedersen, C; Torstensson, M; Ødum, L, 2016)
"To report a case of the syndrome of inappropriate secretion of antidiuretic hormone (SIADH) associated with use of citalopram in an elderly male patient and to review the English-language literature for any previous reports of SIADH or hyponatremia caused by citalopram."3.71Citalopram-associated SIADH. ( Barclay, TS; Lee, AJ, 2002)
"Bupropion is an antidepressant agent usually reserved as an augmentation strategy for treatment-resistant depression."1.42Hyponatraemia and confusion in a 70-year-old female when bupropion was added to dothiepin and escitalopram. ( Balasubramanian, T; Ferraro, A; Wiggins, A, 2015)
"To quantify the importance of drug-drug interactions (DDIs) in the occurrence of adverse drug reactions (ADRs) reported with serotoninergic reuptake inhibitors in a pharmacovigilance database."1.38The importance of drug-drug interactions as a cause of adverse drug reactions: a pharmacovigilance study of serotoninergic reuptake inhibitors in France. ( Bagheri, H; Bondon-Guitton, E; Bui, E; Durrieu, G; Lapeyre-Mestre, M; Montastruc, F; Montastruc, JL; Schmitt, L; Sommet, A, 2012)
"Rhabdomyolysis has rarely been associated with the correction of hyponatraemia."1.37Rhabdomyolysis associated with polydipsia induced hyponatraemia. ( Bennett, M; Donnelly, M; Fitzpatrick, G, 2011)
"Depression is a common problem in elderly patients and frequently is treated with antidepressants."1.33Recurrent hyponatremia associated with citalopram and mirtazapine. ( Akcay, A; Bavbek, N; Kargili, A; Kaya, A, 2006)
"Citalopram was discontinued and fluid restriction was instituted."1.32Severe symptomatic hyponatremia during citalopram therapy--a case report. ( Cobos-Ayala, C; Flores, G; Perez-Patrigeon, S; Vergara, J, 2004)

Research

Studies (32)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's3 (9.38)18.2507
2000's14 (43.75)29.6817
2010's13 (40.63)24.3611
2020's2 (6.25)2.80

Authors

AuthorsStudies
Albalawi, A1
Chiu, CY1
Sarwal, A1
Azhar Munir, R1
Widjaja, M1
Khalid, A1
Khanna, R1
McGuire, E1
Yohanathan, M1
Lally, L1
McCarthy, G1
Vidyasagar, S1
Rao, K1
Verma, M1
Tripuraneni, AD1
Patil, N1
Bhattacharjee, D1
Naschitz, JE1
Pae, CU1
Park, GY1
Im, S1
Ko, SB1
Lee, SJ1
Richter, T1
Paluch, Z1
Alusik, S1
Damali Amiri, N1
Wijenaike, N1
Soysal, P1
Isik, AT1
Chen, LF1
Chi, HC1
Lin, CE1
Wiggins, A1
Balasubramanian, T1
Ferraro, A1
Diken, Aİ1
Yalçınkaya, A1
Erçen Diken, Ö1
Aksoy, E1
Doğan, İ1
Yılmaz, S1
Çağlı, K1
Leth-Møller, KB1
Hansen, AH1
Torstensson, M1
Andersen, SE1
Ødum, L1
Gislasson, G1
Torp-Pedersen, C1
Holm, EA1
Franco Hidalgo, S1
Prieto de Paula, JM1
Salado Valdivieso, I1
Montastruc, F1
Sommet, A1
Bondon-Guitton, E1
Durrieu, G1
Bui, E1
Bagheri, H1
Lapeyre-Mestre, M1
Schmitt, L1
Montastruc, JL1
Bennett, M1
Fitzpatrick, G1
Donnelly, M1
Barclay, TS1
Lee, AJ1
Fisher, A1
Davis, M1
Croft-Baker, J1
Purcell, P1
McLean, A1
Holland, S1
Townley, S1
Summerfield, R1
Flores, G1
Perez-Patrigeon, S1
Cobos-Ayala, C1
Vergara, J1
Nahshoni, E1
Weizman, A1
Shefet, D1
Pik, N1
Miehle, K1
Paschke, R1
Koch, CA1
Bavbek, N1
Kargili, A1
Akcay, A1
Kaya, A1
Covyeou, JA1
Jackson, CW1
Grover, S1
Biswas, P1
Bhateja, G1
Kulhara, P1
Dirks, AC1
van Hyfte, DM1
Hohage, H1
Zeh, M1
Voegeli, J1
Baumann, P1
Spigset, O1
Adielsson, G1
Riquelme, A1
Méndez, F1
Ortiz, AM1
Müller, H1
Campos, C1
Rocha, V1
Valdivieso, A1
Odeh, M1
Beny, A1
Oliven, A1
Hüll, M1
Kottlors, M1
Braune, S1

Reviews

2 reviews available for citalopram and Hyponatremia

ArticleYear
The non-antidepressant effects of citalopram: a clinician's perspective.
    Neuro endocrinology letters, 2014, Volume: 35, Issue:1

    Topics: Citalopram; Humans; Hyponatremia; Osteoporosis; Platelet Aggregation Inhibitors; Romano-Ward Syndrom

2014
Citalopram-induced severe hyponatraemia with coma and seizure. Case report with literature and spontaneous reports review.
    Adverse drug reactions and toxicological reviews, 2002, Volume: 21, Issue:4

    Topics: Adult; Aged; Aged, 80 and over; Citalopram; Coma; Female; Humans; Hyponatremia; Male; Middle Aged; S

2002

Other Studies

30 other studies available for citalopram and Hyponatremia

ArticleYear
Deep venous thrombosis and hyponatremia associated with citalopram use for behavioral symptoms in Parkinson's disease: a case report.
    BMC geriatrics, 2023, 06-01, Volume: 23, Issue:1

    Topics: Aged; Aged, 80 and over; Behavioral Symptoms; Citalopram; Dementia; Female; Humans; Hyponatremia; Pa

2023
Syndrome of Inappropriate Antidiuretic Hormone (SIADH) Induced by Long-Term Use of Citalopram and Short-Term Use of Naproxen.
    The American journal of case reports, 2020, Sep-18, Volume: 21

    Topics: Aged; Aged, 80 and over; Citalopram; Female; Humans; Hyponatremia; Inappropriate ADH Syndrome; Napro

2020
Hyponatraemia-associated catatonia.
    BMJ case reports, 2017, Jul-14, Volume: 2017

    Topics: Aged; Catatonia; Citalopram; Diagnosis, Differential; Humans; Hyponatremia; Male; Selective Serotoni

2017
Escitalopram Induced SIADH in an Elderly Female: A Case Study.
    Psychopharmacology bulletin, 2017, 09-15, Volume: 47, Issue:4

    Topics: Citalopram; Dysthymic Disorder; Female; Humans; Hyponatremia; Inappropriate ADH Syndrome; Middle Age

2017
Escitalopram Dose-Dependent Hyponatremia.
    Journal of clinical pharmacology, 2018, Volume: 58, Issue:6

    Topics: Aged; Citalopram; Dose-Response Relationship, Drug; Female; Humans; Hyponatremia; Selective Serotoni

2018
Low-dose escitalopram-associated hyponatremia.
    Asia-Pacific psychiatry : official journal of the Pacific Rim College of Psychiatrists, 2013, Volume: 5, Issue:2

    Topics: Antidepressive Agents, Second-Generation; Citalopram; Depressive Disorder, Major; Humans; Hyponatrem

2013
Citalopram-induced hyponatraemia and parkinsonism: potentially fatal side-effects not to be missed.
    BMJ case reports, 2014, Nov-12, Volume: 2014

    Topics: Aged; Citalopram; Confusion; Humans; Hyponatremia; Male; Parkinsonian Disorders; Selective Serotonin

2014
Severe hyponatremia due to escitalopram treatment in an elderly adult with Alzheimer's disease.
    Journal of the American Geriatrics Society, 2014, Volume: 62, Issue:12

    Topics: Aged; Alzheimer Disease; Citalopram; Female; Humans; Hyponatremia; Selective Serotonin Reuptake Inhi

2014
Hyponatremia masquerading as panic symptoms in bipolar affective disorder.
    The Journal of neuropsychiatry and clinical neurosciences, 2014,Fall, Volume: 26, Issue:4

    Topics: Aged; Anti-Anxiety Agents; Bipolar Disorder; Citalopram; Estazolam; Female; Humans; Hyponatremia; Pa

2014
Hyponatraemia and confusion in a 70-year-old female when bupropion was added to dothiepin and escitalopram.
    Australasian psychiatry : bulletin of Royal Australian and New Zealand College of Psychiatrists, 2015, Volume: 23, Issue:5

    Topics: Aged; Antidepressive Agents; Bupropion; Citalopram; Confusion; Depressive Disorder, Treatment-Resist

2015
Hyponatremia Due to Escitalopram and Thiazide Use After Cardiac Surgery.
    Journal of cardiac surgery, 2016, Volume: 31, Issue:2

    Topics: Antidepressive Agents; Citalopram; Coronary Artery Bypass; Depression; Drug Therapy, Combination; Em

2016
Antidepressants and the risk of hyponatremia: a Danish register-based population study.
    BMJ open, 2016, 05-18, Volume: 6, Issue:5

    Topics: Adult; Aged; Antidepressive Agents, Tricyclic; Citalopram; Clomipramine; Denmark; Duloxetine Hydroch

2016
[Citalopram and syndrome of inappropriate secretion of antidiuretic hormone].
    Endocrinologia y nutricion : organo de la Sociedad Espanola de Endocrinologia y Nutricion, 2009, Volume: 56, Issue:1

    Topics: Aged, 80 and over; Citalopram; Female; Humans; Hyponatremia; Inappropriate ADH Syndrome; Selective S

2009
The importance of drug-drug interactions as a cause of adverse drug reactions: a pharmacovigilance study of serotoninergic reuptake inhibitors in France.
    European journal of clinical pharmacology, 2012, Volume: 68, Issue:5

    Topics: Adult; Adverse Drug Reaction Reporting Systems; Age Factors; Antidepressive Agents; Citalopram; Conf

2012
Rhabdomyolysis associated with polydipsia induced hyponatraemia.
    BMJ case reports, 2011, Oct-04, Volume: 2011

    Topics: Adult; Antidepressive Agents, Second-Generation; Citalopram; Depression; Diagnosis, Differential; Hu

2011
Citalopram-associated SIADH.
    The Annals of pharmacotherapy, 2002, Volume: 36, Issue:10

    Topics: Aged; Aged, 80 and over; Citalopram; Humans; Hyponatremia; Inappropriate ADH Syndrome; Male; Selecti

2002
Citalopram--a risk factor for postoperative hyponatraemia.
    Anaesthesia, 2003, Volume: 58, Issue:5

    Topics: Aged; Antidepressive Agents, Second-Generation; Citalopram; Female; Humans; Hyponatremia; Postoperat

2003
Severe symptomatic hyponatremia during citalopram therapy--a case report.
    BMC nephrology, 2004, Jan-16, Volume: 5

    Topics: Citalopram; Humans; Hyponatremia; Inappropriate ADH Syndrome; Male; Middle Aged; Seizures; Selective

2004
A case of hyponatremia associated with escitalopram.
    The Journal of clinical psychiatry, 2004, Volume: 65, Issue:12

    Topics: Citalopram; Depressive Disorder, Major; Female; Humans; Hyponatremia; Inappropriate ADH Syndrome; Mi

2004
Citalopram therapy as a risk factor for symptomatic hyponatremia caused by the syndrome of inappropriate secretion of antidiuretic hormone (SIADH): a case report.
    Pharmacopsychiatry, 2005, Volume: 38, Issue:4

    Topics: Aged; Aged, 80 and over; Antidepressive Agents; Citalopram; Depressive Disorder; Female; Humans; Hyp

2005
Recurrent hyponatremia associated with citalopram and mirtazapine.
    American journal of kidney diseases : the official journal of the National Kidney Foundation, 2006, Volume: 48, Issue:4

    Topics: Aged; Antidepressive Agents; Antidepressive Agents, Tricyclic; Citalopram; Depression; Diagnosis, Di

2006
Hyponatremia associated with escitalopram.
    The New England journal of medicine, 2007, Jan-04, Volume: 356, Issue:1

    Topics: Aged; Antidepressive Agents, Second-Generation; Citalopram; Female; Humans; Hyponatremia; Inappropri

2007
Escitalopram-associated hyponatremia.
    Psychiatry and clinical neurosciences, 2007, Volume: 61, Issue:1

    Topics: Aged; Antidepressive Agents; Anxiety Disorders; Bipolar Disorder; Citalopram; Electrocardiography; F

2007
Recurrent hyponatremia after substitution of citalopram with duloxetine.
    Journal of clinical psychopharmacology, 2007, Volume: 27, Issue:3

    Topics: Aged, 80 and over; Antidepressive Agents, Tricyclic; Citalopram; Depression; Duloxetine Hydrochlorid

2007
[Nausea and confusion in a diabetic patient. Hyponatremia as an incidental finding].
    MMW Fortschritte der Medizin, 2006, Nov-09, Volume: 148, Issue:45

    Topics: Antidepressive Agents, Second-Generation; Citalopram; Confusion; Diabetes Mellitus; Diagnosis, Diffe

2006
Inappropriate secretion of antidiuretic hormone and SSRIs.
    The British journal of psychiatry : the journal of mental science, 1996, Volume: 169, Issue:4

    Topics: Aged; Bipolar Disorder; Citalopram; Drug Therapy, Combination; Female; Humans; Hydrochlorothiazide;

1996
Combined serotonin syndrome and hyponatraemia caused by a citalopram-buspirone interaction.
    International clinical psychopharmacology, 1997, Volume: 12, Issue:1

    Topics: Aged; Buspirone; Citalopram; Depressive Disorder; Drug Interactions; Female; Humans; Hyponatremia; M

1997
[Severe and recent hyponatremia and hypokalemia associated to the use of hydrochlorothiazide, enalapril and citalopram. Clinical case].
    Revista medica de Chile, 1999, Volume: 127, Issue:10

    Topics: Aged; Antidepressive Agents, Second-Generation; Antihypertensive Agents; Citalopram; Enalapril; Fema

1999
Severe symptomatic hyponatremia during citalopram therapy.
    The American journal of the medical sciences, 2001, Volume: 321, Issue:2

    Topics: Aged; Citalopram; Depression; Female; Humans; Hyponatremia; Inappropriate ADH Syndrome; Selective Se

2001
Prolonged coma caused by low sodium and hypo-osmolarity during treatment with citalopram.
    Journal of clinical psychopharmacology, 2002, Volume: 22, Issue:3

    Topics: Citalopram; Coma; Female; Humans; Hyponatremia; Middle Aged; Osmolar Concentration; Selective Seroto

2002