citalopram has been researched along with Glioma in 6 studies
Citalopram: A furancarbonitrile that is one of the serotonin uptake inhibitors used as an antidepressant. The drug is also effective in reducing ethanol uptake in alcoholics and is used in depressed patients who also suffer from TARDIVE DYSKINESIA in preference to tricyclic antidepressants, which aggravate dyskinesia.
citalopram : A racemate comprising equimolar amounts of (R)-citalopram and its enantiomer, escitalopram. It is used as an antidepressant, although only escitalopram is active.
1-[3-(dimethylamino)propyl]-1-(4-fluorophenyl)-1,3-dihydro-2-benzofuran-5-carbonitrile : A nitrile that is 1,3-dihydro-2-benzofuran-5-carbonitrile in which one of the hydrogens at position 1 is replaced by a p-fluorophenyl group, while the other is replaced by a 3-(dimethylamino)propyl group.
Glioma: Benign and malignant central nervous system neoplasms derived from glial cells (i.e., astrocytes, oligodendrocytes, and ependymocytes). Astrocytes may give rise to astrocytomas (ASTROCYTOMA) or glioblastoma multiforme (see GLIOBLASTOMA). Oligodendrocytes give rise to oligodendrogliomas (OLIGODENDROGLIOMA) and ependymocytes may undergo transformation to become EPENDYMOMA; CHOROID PLEXUS NEOPLASMS; or colloid cysts of the third ventricle. (From Escourolle et al., Manual of Basic Neuropathology, 2nd ed, p21)
| Excerpt | Relevance | Reference |
|---|---|---|
| "In C6 glioma cells, we studied acute administration of SSRI antidepressants - fluoxetine, sertraline and citalopram." | 7.78 | Effect of fluoxetine and adenosine receptor NECA agonist on G alpha q/11 protein of C6 glioma cells. ( Kováru, F; Kovárů, H; Lisá, V, 2012) |
| "The effects of chronic treatment with antidepressants, verapamil, or lithium on serotonin (5-HT)-induced Ca2+ increase were investigated in single C6BU-1 glioma cells with digital imaging microscopy." | 7.69 | Chronic treatment with antidepressants, verapamil, or lithium inhibits the serotonin-induced intracellular calcium response in individual C6 rat glioma cells. ( Kagaya, A; Uchitomi, Y; Yamaji, T; Yamawaki, S; Yokota, N, 1997) |
| "Because both imipramine and citalopram have been commonly used to treat depression, which commonly occurs in glioma patients, it would be interesting to conduct large epidemiological studies to investigate the actual benefit that these two drugs would provide for malignant glioma patients when delivered during their glioma treatment." | 3.78 | Voltage-dependent K+ channels as oncotargets in malignant gliomas. ( De Witte, O; Lefranc, F; Pouleau, HB; Rynkowski, M, 2012) |
| "In C6 glioma cells, we studied acute administration of SSRI antidepressants - fluoxetine, sertraline and citalopram." | 3.78 | Effect of fluoxetine and adenosine receptor NECA agonist on G alpha q/11 protein of C6 glioma cells. ( Kováru, F; Kovárů, H; Lisá, V, 2012) |
| "The effects of chronic treatment with antidepressants, verapamil, or lithium on serotonin (5-HT)-induced Ca2+ increase were investigated in single C6BU-1 glioma cells with digital imaging microscopy." | 3.69 | Chronic treatment with antidepressants, verapamil, or lithium inhibits the serotonin-induced intracellular calcium response in individual C6 rat glioma cells. ( Kagaya, A; Uchitomi, Y; Yamaji, T; Yamawaki, S; Yokota, N, 1997) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (33.33) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 4 (66.67) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Chen, VC | 1 |
| Hsieh, YH | 1 |
| Chen, LJ | 1 |
| Hsu, TC | 1 |
| Tzang, BS | 1 |
| Lefranc, F | 1 |
| Pouleau, HB | 1 |
| Rynkowski, M | 1 |
| De Witte, O | 1 |
| Kovárů, H | 1 |
| Kováru, F | 1 |
| Lisá, V | 1 |
| Malynn, S | 1 |
| Campos-Torres, A | 1 |
| Moynagh, P | 1 |
| Haase, J | 1 |
| Kagaya, A | 2 |
| Kugaya, A | 1 |
| Hayashi, T | 1 |
| Okamoto, Y | 1 |
| Takebayashi, M | 1 |
| Uchitomi, Y | 2 |
| Yamawaki, S | 2 |
| Yamaji, T | 1 |
| Yokota, N | 1 |
6 other studies available for citalopram and Glioma
| Article | Year |
|---|---|
Escitalopram oxalate induces apoptosis in U-87MG cells and autophagy in GBM8401 cells.
Topics: Animals; Apoptosis; Autophagy; Cell Cycle Proteins; Cell Line, Tumor; Cell Movement; Cell Proliferat | 2018 |
Voltage-dependent K+ channels as oncotargets in malignant gliomas.
Topics: Animals; Antidepressive Agents; Apoptosis; Brain Neoplasms; Cell Movement; Citalopram; Drug Resistan | 2012 |
Effect of fluoxetine and adenosine receptor NECA agonist on G alpha q/11 protein of C6 glioma cells.
Topics: Adenosine-5'-(N-ethylcarboxamide); Animals; Brain Neoplasms; Cell Line, Tumor; Citalopram; Depressio | 2012 |
The pro-inflammatory cytokine TNF-α regulates the activity and expression of the serotonin transporter (SERT) in astrocytes.
Topics: Astrocytes; Cell Line, Tumor; Citalopram; Fluoxetine; Glioma; Humans; Imidazoles; p38 Mitogen-Activa | 2013 |
Effect of citalopram on the desensitization of serotonin-2A receptor-mediated calcium mobilization in rat glioma cells.
Topics: Animals; Brain Neoplasms; Calcium; Citalopram; Dose-Response Relationship, Drug; Glioma; Rats; Recep | 1996 |
Chronic treatment with antidepressants, verapamil, or lithium inhibits the serotonin-induced intracellular calcium response in individual C6 rat glioma cells.
Topics: Animals; Antidepressive Agents; Calcium; Calcium Channel Blockers; Citalopram; Clomipramine; Drug In | 1997 |