citalopram has been researched along with Gastroesophageal Reflux in 10 studies
Citalopram: A furancarbonitrile that is one of the serotonin uptake inhibitors used as an antidepressant. The drug is also effective in reducing ethanol uptake in alcoholics and is used in depressed patients who also suffer from TARDIVE DYSKINESIA in preference to tricyclic antidepressants, which aggravate dyskinesia.
citalopram : A racemate comprising equimolar amounts of (R)-citalopram and its enantiomer, escitalopram. It is used as an antidepressant, although only escitalopram is active.
1-[3-(dimethylamino)propyl]-1-(4-fluorophenyl)-1,3-dihydro-2-benzofuran-5-carbonitrile : A nitrile that is 1,3-dihydro-2-benzofuran-5-carbonitrile in which one of the hydrogens at position 1 is replaced by a p-fluorophenyl group, while the other is replaced by a 3-(dimethylamino)propyl group.
Gastroesophageal Reflux: Retrograde flow of gastric juice (GASTRIC ACID) and/or duodenal contents (BILE ACIDS; PANCREATIC JUICE) into the distal ESOPHAGUS, commonly due to incompetence of the LOWER ESOPHAGEAL SPHINCTER.
| Excerpt | Relevance | Reference |
|---|---|---|
| "All NCCP patients underwent impedance-pH monitoring and on the basis of the results, those with abnormal distal esophageal acid exposure received PPIs twice daily (group A), those with a positive symptom index for chest pain received citalopram 20 mg and PPI once daily (group B), and those with a negative symptom index for chest pain received citalopram 20 mg once daily (group C)." | 3.85 | Proton pump inhibitor and selective serotonin reuptake inhibitor therapy for the management of noncardiac chest pain. ( Christidou, A; Denaxas, K; Galanopoulos, M; Kamberoglou, D; Karamanolis, DG; Karamanolis, G; Katopodi, K; Mantzaris, GJ; Papatheodoridis, G; Tsoukali, E; Varytimiadis, L; Viazis, N, 2017) |
| "No cardiac rhythm disturbances or convulsions were seen." | 1.56 | Citalopram intoxication in four week old infant. ( Eijkemans, M; Janson, JA; Kerskes, M; Wasylewicz, ATM, 2020) |
| " Trials of citalopram and escitalopram were associated with reports of persistent nausea and gastric reflux unresolved by changes in dosing schedule or positioning." | 1.37 | Antidepressant-mediated gastroesophageal reflux disease. ( Brahm, NC; Kelly-Rehm, MC, 2011) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (20.00) | 29.6817 |
| 2010's | 6 (60.00) | 24.3611 |
| 2020's | 2 (20.00) | 2.80 |
| Authors | Studies |
|---|---|
| Broers, C | 2 |
| Geeraerts, A | 1 |
| Boecxstaens, V | 1 |
| Van Houtte, B | 2 |
| Geysen, H | 2 |
| Peersman, N | 1 |
| Vermeersch, P | 1 |
| Vanuytsel, T | 2 |
| Tack, J | 2 |
| Pauwels, A | 2 |
| Janson, JA | 1 |
| Wasylewicz, ATM | 1 |
| Eijkemans, M | 1 |
| Kerskes, M | 1 |
| Viazis, N | 2 |
| Katopodi, K | 1 |
| Karamanolis, G | 2 |
| Denaxas, K | 1 |
| Varytimiadis, L | 1 |
| Galanopoulos, M | 1 |
| Tsoukali, E | 1 |
| Kamberoglou, D | 1 |
| Christidou, A | 1 |
| Karamanolis, DG | 2 |
| Papatheodoridis, G | 1 |
| Mantzaris, GJ | 1 |
| Manolakis, AC | 1 |
| Goelen, N | 1 |
| Rommel, N | 1 |
| Lee, TH | 1 |
| Lee, JS | 1 |
| Celikbilek, A | 1 |
| Celikbilek, M | 1 |
| Akyol, L | 1 |
| Pirti, I | 1 |
| Brahm, NC | 1 |
| Kelly-Rehm, MC | 1 |
| Keyoglou, A | 1 |
| Kanellopoulos, AK | 1 |
| Vlachogiannakos, J | 1 |
| Triantafyllou, K | 1 |
| Ladas, SD | 1 |
| Rykova, SM | 1 |
| Pogromov, AP | 1 |
| Diukova, GM | 1 |
| Veĭn, AM | 1 |
| Mansfield, P | 1 |
| Henry, D | 1 |
| Tonkin, A | 1 |
1 review available for citalopram and Gastroesophageal Reflux
| Article | Year |
|---|---|
Single-enantiomer drugs: elegant science, disappointing effects.
Topics: Albuterol; Anti-Asthmatic Agents; Anti-Ulcer Agents; Antidepressive Agents, Second-Generation; Cital | 2004 |
2 trials available for citalopram and Gastroesophageal Reflux
| Article | Year |
|---|---|
Effect of citalopram on esophageal motility in healthy subjects-Implications for reflux episodes, dysphagia, and globus.
Topics: Citalopram; Deglutition Disorders; Esophagogastric Junction; Esophagus; Female; Gastroesophageal Ref | 2019 |
Selective serotonin reuptake inhibitors for the treatment of hypersensitive esophagus: a randomized, double-blind, placebo-controlled study.
Topics: Adolescent; Adult; Aged; Citalopram; Double-Blind Method; Esophageal pH Monitoring; Female; Gastroes | 2012 |
7 other studies available for citalopram and Gastroesophageal Reflux
| Article | Year |
|---|---|
The role of serotonin in the control of esophageal sensitivity assessed by multimodal stimulation in health.
Topics: Adult; Buspirone; Citalopram; Esophagus; Female; Gastroesophageal Reflux; Healthy Volunteers; Humans | 2021 |
Citalopram intoxication in four week old infant.
Topics: Child; Citalopram; Gastroesophageal Reflux; Humans; Infant; Seizures; Substance-Related Disorders | 2020 |
Proton pump inhibitor and selective serotonin reuptake inhibitor therapy for the management of noncardiac chest pain.
Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Chest Pain; Citalopram; Drug Therapy, Combination; Electric | 2017 |
An electrocardiograph should be examined in patients with a hypersensitive esophagus before a trial of citalopram.
Topics: Biomarkers; Citalopram; Controlled Clinical Trials as Topic; Electrocardiography; Esophagus; Gastroe | 2013 |
Esomeprazole-induced irritability.
Topics: Adult; Antidepressive Agents, Second-Generation; Citalopram; Esomeprazole; Female; Gastritis; Gastro | 2014 |
Antidepressant-mediated gastroesophageal reflux disease.
Topics: Antidepressive Agents; Citalopram; Cyclohexanols; Desvenlafaxine Succinate; Female; Gastroesophageal | 2011 |
[Psychophysiologic disorders in patients with functional disorders of upper sections of the gastrointestinal tract and with gastroesophageal reflux disease].
Topics: Antidepressive Agents, Second-Generation; Citalopram; Esophageal Diseases; Gastroesophageal Reflux; | 2003 |