Page last updated: 2024-10-25

citalopram and Drug Overdose

citalopram has been researched along with Drug Overdose in 70 studies

Citalopram: A furancarbonitrile that is one of the serotonin uptake inhibitors used as an antidepressant. The drug is also effective in reducing ethanol uptake in alcoholics and is used in depressed patients who also suffer from TARDIVE DYSKINESIA in preference to tricyclic antidepressants, which aggravate dyskinesia.
citalopram : A racemate comprising equimolar amounts of (R)-citalopram and its enantiomer, escitalopram. It is used as an antidepressant, although only escitalopram is active.
1-[3-(dimethylamino)propyl]-1-(4-fluorophenyl)-1,3-dihydro-2-benzofuran-5-carbonitrile : A nitrile that is 1,3-dihydro-2-benzofuran-5-carbonitrile in which one of the hydrogens at position 1 is replaced by a p-fluorophenyl group, while the other is replaced by a 3-(dimethylamino)propyl group.

Drug Overdose: Accidental or deliberate use of a medication or street drug in excess of normal dosage.

Research Excerpts

ExcerptRelevanceReference
"Citalopram overdose may be associated with severe serotonin syndrome and further investigation is warranted to understand the impact of enzyme genotype on toxicity."7.91Citalopram overdose and severe serotonin syndrome in an intermediate metabolizing patient. ( Morris, AJ; Picard, L; Schult, RF; Wiegand, TJ, 2019)
"Metaxalone has only recently been associated with serotonin syndrome."7.81Serotonin syndrome following metaxalone overdose and therapeutic use of a selective serotonin reuptake inhibitor. ( Cobb, T; Haswell, D; Hodgman, M; Martini, DI; Nacca, N, 2015)
" Citalopram, a newer generation SSRI, is commonly prescribed, but despite its low toxicity profile has a potential to cause seizures and dysarrythmias in overdose."7.76Metabolic acidosis and generalized seizures secondary to citalopram overdose: a case report. ( Al Anazi, T; Al Hayyan, H; Al Hussein, M; Al Modaimegh, H; Al Qahtani, M; Bin Salih, S, 2010)
"Seizures are a recognized complication of acute overdose with the racemic (1:1 ratio of R- and S-enantiomers) selective serotonin reuptake inhibitor antidepressant citalopram."7.76Escitalopram causes fewer seizures in human overdose than citalopram. ( Bauer, K; Ceschi, A; Gerber-Zupan, G; Hackl, E; Hoffmann-Walbeck, P; Kullak-Ublick, GA; Kupferschmidt, H; Prasa, D; Rauber-Lüthy, C; Sauer, O; Seidel, C; Stedtler, U; Wilks, M; Yilmaz, Z, 2010)
"Generalized seizures are an important manifestation of citalopram toxicity, and cannot be explained solely by electrolyte disturbances or co-ingestion of other drugs or ethanol."7.74Predictive factors for generalized seizures after deliberate citalopram overdose. ( Graham, A; Gray, JA; Waring, WS, 2008)
" Several hours after presentation, she developed sinus arrest and junctional bradycardia that resolved after infusion of intravenous sodium bicarbonate solution."7.73Reversal of citalopram-induced junctional bradycardia with intravenous sodium bicarbonate. ( Brucculeri, M; Kaplan, J; Lande, L, 2005)
"Citalopram has been associated with seizures, ECG abnormalities, rhabdomyolysis and coma after overdose."5.32Adult respiratory distress syndrome and renal failure associated with citalopram overdose. ( Bateman, DN; Flanagan, RJ; Kelly, CA; Spencer, EP; Upex, A, 2003)
"Citalopram overdose may be associated with severe serotonin syndrome and further investigation is warranted to understand the impact of enzyme genotype on toxicity."3.91Citalopram overdose and severe serotonin syndrome in an intermediate metabolizing patient. ( Morris, AJ; Picard, L; Schult, RF; Wiegand, TJ, 2019)
"Citalopram is a selective serotonin reuptake inhibitor (SSRI) with cardiac and neurologic toxicities as well as the potential for serotonin syndrome."3.81Citalopram Overdose: a Fatal Case. ( Kraai, EP; Seifert, SA, 2015)
"Metaxalone has only recently been associated with serotonin syndrome."3.81Serotonin syndrome following metaxalone overdose and therapeutic use of a selective serotonin reuptake inhibitor. ( Cobb, T; Haswell, D; Hodgman, M; Martini, DI; Nacca, N, 2015)
"Antidepressants were frequently associated with seizures in overdose, but other pharmaceuticals, as mefenamic acid, were also associated with seizures in a considerable number of cases."3.80Seizures after single-agent overdose with pharmaceutical drugs: analysis of cases reported to a poison center. ( Ceschi, A; Kupferschmidt, H; Monnet-Tschudi, F; Rauber-Lüthy, C; Reichert, C; Reichert, P, 2014)
"This is a case of a citalopram and olanzapine overdose causing seizures and severe cardiotoxicity."3.79Cardiotoxicity in a citalopram and olanzapine overdose. ( Gerona, RR; Lung, DD; Wu, AH, 2013)
"The purpose of the present study is to determine the role of lidocaine, caffeine and dextromethorphan, used as adulterant substances, in five cases of drug overdose which have come to our attention."3.79The pathogenetic role of adulterants in 5 cases of drug addicts with a fatal outcome. ( Barbera, N; Busardò, FP; Indorato, F; Romano, G, 2013)
" We report the case of a 54-year-old patient who developed QTc interval prolongation, followed by ventricular fibrillation episodes, 10 hours after admission to the ICU, in the setting of a citalopram overdose."3.77Drug monitoring of a case of citalopram overdosage. ( Coudoré, F; Liotier, J, 2011)
"Escitalopram seems to be less toxic than citalopram after an acute overdose; seizures and tremors were more common with citalopram."3.76Comparison of toxicity of acute overdoses with citalopram and escitalopram. ( Clark, RF; Hayes, BD; Klein-Schwartz, W; Miloradovich, JE; Muller, AA, 2010)
"Seizures are a recognized complication of acute overdose with the racemic (1:1 ratio of R- and S-enantiomers) selective serotonin reuptake inhibitor antidepressant citalopram."3.76Escitalopram causes fewer seizures in human overdose than citalopram. ( Bauer, K; Ceschi, A; Gerber-Zupan, G; Hackl, E; Hoffmann-Walbeck, P; Kullak-Ublick, GA; Kupferschmidt, H; Prasa, D; Rauber-Lüthy, C; Sauer, O; Seidel, C; Stedtler, U; Wilks, M; Yilmaz, Z, 2010)
" Citalopram, a newer generation SSRI, is commonly prescribed, but despite its low toxicity profile has a potential to cause seizures and dysarrythmias in overdose."3.76Metabolic acidosis and generalized seizures secondary to citalopram overdose: a case report. ( Al Anazi, T; Al Hayyan, H; Al Hussein, M; Al Modaimegh, H; Al Qahtani, M; Bin Salih, S, 2010)
" A 52-year-old man with a history of depression treated with escitalopram 10 mg/day, extended-release morphine 30 mg/day and zopiclone 15 mg/day was found unconscious at his home."3.74Corrected QT interval prolongation after an overdose of escitalopram, morphine, oxycodone, zopiclone and benzodiazepines. ( Baranchuk, A; Gibson, K; Methot, M; Simpson, CS; Strum, D, 2008)
"Generalized seizures are an important manifestation of citalopram toxicity, and cannot be explained solely by electrolyte disturbances or co-ingestion of other drugs or ethanol."3.74Predictive factors for generalized seizures after deliberate citalopram overdose. ( Graham, A; Gray, JA; Waring, WS, 2008)
" Several hours after presentation, she developed sinus arrest and junctional bradycardia that resolved after infusion of intravenous sodium bicarbonate solution."3.73Reversal of citalopram-induced junctional bradycardia with intravenous sodium bicarbonate. ( Brucculeri, M; Kaplan, J; Lande, L, 2005)
"Depression, a common condition in MS patients, was precipitated in this patient by the spontaneous discontinuation of citalopram and not influenced by IFN beta-1a therapy, which the patient resumed at 44 mug 3 times per week."3.73Interferon beta-1a overdose in a multiple sclerosis patient. ( Falcone, NP; Nappo, A; Neuteboom, B, 2005)
"We report a case of citalopram poisoning in a 10-month-old infant with refractory seizures, and an absence of cardiovascular events with subsequent excellent outcome."3.73Clinical course and toxicokinetic data following isolated citalopram overdose in an infant. ( Baker, SD; Bose, S; Levsky, M; Masullo, LN; Miller, MA, 2006)
" At very high doses (> 75 times the common daily dose), more serious adverse events, including seizures, electrocardiogram (ECG) changes, and decreased consciousness may occur."2.40SSRI safety in overdose. ( Barbey, JT; Roose, SP, 1998)
"3, first for a population pharmacokinetic (PK) analysis followed by a PKPD analysis."1.38Population pharmacokinetics and pharmacodynamics of escitalopram in overdose and the effect of activated charcoal. ( Duffull, S; Hackett, LP; Isbister, GK; van Gorp, F, 2012)
"Citalopram overdose was more likely to be associated with QT higher than the nomogram compared with the other agents (difference 7."1.36Evaluation of a QT nomogram for risk assessment after antidepressant overdose. ( Bateman, DN; Graham, A; Gray, J; Howell, C; Waring, WS; Wilson, AD, 2010)
" The aim of this study was to investigate the toxic effects and toxicokinetic parameters of citalopram in an overdose as a single drug and in combination with other drugs."1.35Clinical toxicology of citalopram after acute intoxication with the sole drug or in combination with other drugs: overview of 26 cases. ( Caminada, K; Hunfeld, NG; Jimmink, A; Touw, DJ, 2008)
"Citalopram overdose may produce bradycardia, QT prolongation, and torsades de pointes (TdP)."1.35Citalopram overdose: late presentation of torsades de pointes (TdP) with cardiac arrest. ( Hoffman, RS; Nelson, L; Tarabar, AF, 2008)
"Citalopram has been regarded as the most toxic of the selective serotonin reuptake inhibitors in overdose; however, hypoglycaemia is not one of the documented features of overdose."1.35Severe hypoglycaemia in citalopram overdose. ( Armstrong, PA; Duncan, RA; Paterson, B, 2008)
"To report the successful use of high dose insulin (HDI) in previously unreported insulin dosing ranges in a patient with severe myocardial toxicity due to an amitriptyline and citalopram overdose."1.35High dose insulin in toxic cardiogenic shock. ( Engebretsen, KM; Holger, JS; Marini, JJ, 2009)
"There were no deaths, seizures, or arrhythmias."1.35Clinical and ECG effects of escitalopram overdose. ( Isbister, GK; van Gorp, F; Whyte, IM, 2009)
"The patho-physiological basis for acute angle closure glaucoma in relation to antidepressant medications remains unclear."1.33Citalopram associated with acute angle-closure glaucoma: case report. ( Croos, R; Davis, Jda R; Hassan, S; Thirumalai, S, 2005)
"Escitalopram (ESC) is a new selective serotonin reuptake inhibitor (SSRI) used in the treatment of depression."1.33Outcomes after supratherapeutic escitalopram ingestions. ( Knight, J; LoVecchio, F; McDowell, T; Watts, D; Winchell, J, 2006)
"Citalopram has been associated with seizures, ECG abnormalities, rhabdomyolysis and coma after overdose."1.32Adult respiratory distress syndrome and renal failure associated with citalopram overdose. ( Bateman, DN; Flanagan, RJ; Kelly, CA; Spencer, EP; Upex, A, 2003)
"The seizure was successfully treated with benzodiazepines."1.32Seizure secondary to citalopram overdose. ( Cuenca, PJ; Hoefle, JD; Holt, KR, 2004)
"Citalopram was associated with a significantly longer QT interval on ECG recording (p < 0."1.32Comparative toxicity of citalopram and the newer antidepressants after overdose. ( Bateman, DN; Dhaun, N; Good, AM; Kelly, CA; Laing, WJ; Strachan, FE, 2004)

Research

Studies (70)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's12 (17.14)18.2507
2000's34 (48.57)29.6817
2010's23 (32.86)24.3611
2020's1 (1.43)2.80

Authors

AuthorsStudies
Pélissier-Alicot, AL1
Deveaux, M1
Sastre, C1
Baillif-Couniou, V1
Christia, MA1
Champeaux-Fesquet, C1
Leonetti, G1
Young, S1
O'Driscoll, R1
Antony, M1
Whyte, I1
Nedahl, M1
Johansen, SS2
Linnet, K1
Weigl, J1
Vloet, T1
Egberts, K1
Briegel, W1
Kratz, J1
Romanos, M1
Gerlach, M1
Židková, M1
Horsley, R1
Hloch, O1
Hložek, T1
Schult, RF1
Morris, AJ1
Picard, L1
Wiegand, TJ1
Karlsson, L1
Green, H1
Zackrisson, AL1
Bengtsson, F2
Jakobsen Falk, I1
Carlsson, B1
Ahlner, J1
Kugelberg, FC1
Lung, DD1
Wu, AH1
Gerona, RR1
Reichert, C1
Reichert, P1
Monnet-Tschudi, F1
Kupferschmidt, H2
Ceschi, A2
Rauber-Lüthy, C2
Kraai, EP1
Seifert, SA1
Martini, DI1
Nacca, N1
Haswell, D1
Cobb, T1
Hodgman, M1
Arias Palomero, A1
Infantes Molina, EJ1
López Arroquia, E1
Riveira Villalobos, L1
López Mondéjar, E1
González del Valle, F1
Purg, D1
Markota, A1
Grenc, D1
Sinkovič, A1
Jimmink, A1
Caminada, K1
Hunfeld, NG1
Touw, DJ1
Greene, SC1
Brooks, DE1
Lovecchio, F2
Tarabar, AF1
Hoffman, RS1
Nelson, L2
Scharko, AM1
Schumacher, J1
Baranchuk, A1
Simpson, CS1
Methot, M1
Gibson, K1
Strum, D1
Waring, WS3
Gray, JA1
Graham, A2
Farmer, B1
Prosser, J1
Hoffman, R1
Duncan, RA1
Armstrong, PA1
Paterson, B1
Hayes, BD1
Klein-Schwartz, W1
Clark, RF1
Muller, AA1
Miloradovich, JE1
Morris, E1
Green, D1
Graudins, A2
Holger, JS1
Engebretsen, KM2
Marini, JJ1
van Gorp, F2
Whyte, IM2
Isbister, GK6
Yilmaz, Z1
Sauer, O1
Stedtler, U1
Prasa, D1
Seidel, C1
Hackl, E1
Hoffmann-Walbeck, P1
Gerber-Zupan, G1
Bauer, K1
Kullak-Ublick, GA1
Wilks, M1
Bin Salih, S1
Al Qahtani, M1
Al Anazi, T1
Al Hussein, M1
Al Hayyan, H1
Al Modaimegh, H1
Gray, J1
Wilson, AD1
Howell, C1
Bateman, DN5
Mohammed, R1
Norton, J1
Geraci, SA1
Newman, DB1
Koch, CA1
Liotier, J1
Coudoré, F1
Duffull, S1
Hackett, LP1
Lung, D1
Yeh, K1
Kiang, C1
Maddry, JK1
Breyer, K1
Cook, KM1
Heard, K1
Devresse, A1
Maldague, P1
Coulier, B1
Pierard, F1
Gielen, I1
Barbera, N1
Busardò, FP1
Indorato, F1
Romano, G1
Gruszecki, AC1
Kloda, S1
Simmons, GT1
Daly, TM1
Hardy, RW1
Robinson, CA1
Kelly, CA3
Upex, A1
Spencer, EP1
Flanagan, RJ1
Harris, CR1
Wood, JE1
Müller, IB1
Willads Petersen, H1
Theilade, P1
Cuenca, PJ1
Holt, KR1
Hoefle, JD1
Chick, J1
Good, AM2
Masterton, G1
Dhaun, N1
Laing, WJ1
Strachan, FE1
Brucculeri, M1
Kaplan, J1
Lande, L1
Egberts, TC1
Horak, EL1
Jenkins, AJ1
Croos, R1
Thirumalai, S1
Hassan, S1
Davis, Jda R1
Falcone, NP1
Nappo, A1
Neuteboom, B1
Friberg, LE3
Duffull, SB3
Watts, D1
Winchell, J1
Knight, J1
McDowell, T1
Ryysy, R1
Sinisalo, J1
Viitasalo, M1
Masullo, LN1
Miller, MA1
Baker, SD1
Bose, S1
Levsky, M1
Thanacoody, HK1
Manini, A1
Smith, S1
Moskovitz, J1
Stokes, B1
Buckley, NA1
Lee, C1
Gunja, N1
Brown, SG1
MacDonald, E1
Holdgate, A1
Neuvonen, PJ1
Pohjola-Sintonen, S1
Tacke, U1
Vuori, E1
Oström, M1
Eriksson, A1
Thorson, J1
Spigset, O1
Isacsson, G1
Bergman, U1
Personne, M2
Sjöberg, G2
Persson, H2
Grundemar, L1
Wohlfart, B1
Lagerstedt, C1
Eklundh, G1
Glassman, AH1
Power, A1
Hale, AS1
Worm, K1
Dragsholt, C1
Simonsen, K1
Kringsholm, B1
Barbey, JT1
Roose, SP1
Musshoff, F1
Schmidt, P1
Madea, B1
Aydin, N1
Anaç, E1
Cayköylü, A1
Akçay, F1
Dawson, A1
Snider, RD1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Toxicological Screening by GC-MS Among Children Admitted for a First Afebrile Seizure (CASTox): a Pilot Study[NCT03310697]48 participants (Actual)Interventional2017-12-19Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

1 review available for citalopram and Drug Overdose

ArticleYear
SSRI safety in overdose.
    The Journal of clinical psychiatry, 1998, Volume: 59 Suppl 15

    Topics: Adult; Child; Citalopram; Drug Overdose; Fluoxetine; Fluvoxamine; Humans; Paroxetine; Poison Control

1998

Other Studies

69 other studies available for citalopram and Drug Overdose

ArticleYear
Planned complex suicide involving combined drug intoxication and femoral catheterization.
    Journal of forensic sciences, 2021, Volume: 66, Issue:6

    Topics: Adult; Antidepressive Agents, Second-Generation; Catheterization; Chromatography, Liquid; Citalopram

2021
Massive eucalyptus oil overdose.
    Internal medicine journal, 2017, Volume: 47, Issue:9

    Topics: Adult; Antidepressive Agents, Second-Generation; Antidotes; Charcoal; Citalopram; Coma; Drug Overdos

2017
Reference Brain/Blood Concentrations of Citalopram, Duloxetine, Mirtazapine and Sertraline.
    Journal of analytical toxicology, 2018, Apr-01, Volume: 42, Issue:3

    Topics: Antidepressive Agents; Brain; Calibration; Cause of Death; Chromatography, Liquid; Citalopram; Drug

2018
Non-Fatal Intoxication with a High Dose of Citalopram in a Suicidal 14-Year-Old Girl.
    Zeitschrift fur Kinder- und Jugendpsychiatrie und Psychotherapie, 2019, Volume: 47, Issue:2

    Topics: Adolescent; Citalopram; Depression; Diagnostic Tests, Routine; Drug Overdose; Female; Humans; Select

2019
Near-fatal Intoxication with the "New" Synthetic Opioid U-47700: The First Reported Case in the Czech Republic.
    Journal of forensic sciences, 2019, Volume: 64, Issue:2

    Topics: Adult; Benzamides; Benzodiazepines; Chromatography, Liquid; Citalopram; Czech Republic; Drug Overdos

2019
Citalopram overdose and severe serotonin syndrome in an intermediate metabolizing patient.
    The American journal of emergency medicine, 2019, Volume: 37, Issue:10

    Topics: Adult; Citalopram; Cytochrome P-450 CYP2C19; Drug Overdose; Female; Genotype; Humans; Pharmacogenomi

2019
ABCB1 gene polymorphisms are associated with fatal intoxications involving venlafaxine but not citalopram.
    International journal of legal medicine, 2013, Volume: 127, Issue:3

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antidepressive Agents, Second-Generation; ATP Binding Ca

2013
Cardiotoxicity in a citalopram and olanzapine overdose.
    The Journal of emergency medicine, 2013, Volume: 45, Issue:4

    Topics: Adult; Benzodiazepines; Bradycardia; Citalopram; Drug Overdose; Electrocardiography; Humans; Hypoten

2013
Seizures after single-agent overdose with pharmaceutical drugs: analysis of cases reported to a poison center.
    Clinical toxicology (Philadelphia, Pa.), 2014, Volume: 52, Issue:6

    Topics: Adolescent; Adult; Age Factors; Aged; Aged, 80 and over; Antidepressive Agents; Child; Child, Presch

2014
Citalopram Overdose: a Fatal Case.
    Journal of medical toxicology : official journal of the American College of Medical Toxicology, 2015, Volume: 11, Issue:2

    Topics: Adult; Cardiopulmonary Resuscitation; Citalopram; Drug Overdose; Electrocardiography; Fatal Outcome;

2015
Serotonin syndrome following metaxalone overdose and therapeutic use of a selective serotonin reuptake inhibitor.
    Clinical toxicology (Philadelphia, Pa.), 2015, Volume: 53, Issue:3

    Topics: Adult; Citalopram; Drug Interactions; Drug Overdose; Female; Humans; Male; Neuromuscular Agents; Oxa

2015
[Uveal effusion induced by escitalopram].
    Archivos de la Sociedad Espanola de Oftalmologia, 2015, Volume: 90, Issue:7

    Topics: Acute Disease; Aged; Atropine; Brimonidine Tartrate; Choroid Diseases; Ciliary Body; Citalopram; Dru

2015
Low-dose intravenous lipid emulsion for the treatment of severe quetiapine and citalopram poisoning.
    Arhiv za higijenu rada i toksikologiju, 2016, Jun-01, Volume: 67, Issue:2

    Topics: Antidepressive Agents, Second-Generation; Antipsychotic Agents; Bromazepam; Citalopram; Drug Overdos

2016
Clinical toxicology of citalopram after acute intoxication with the sole drug or in combination with other drugs: overview of 26 cases.
    Therapeutic drug monitoring, 2008, Volume: 30, Issue:3

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Cardiovascular Diseases; Central Nervous System Diseases

2008
Effect of activated charcoal on citalopram-induced QT prolongation.
    Annals of emergency medicine, 2008, Volume: 52, Issue:1

    Topics: Adult; Charcoal; Citalopram; Databases, Factual; Drug Overdose; Electrocardiography; Female; Humans;

2008
Citalopram overdose: late presentation of torsades de pointes (TdP) with cardiac arrest.
    Journal of medical toxicology : official journal of the American College of Medical Toxicology, 2008, Volume: 4, Issue:2

    Topics: Adult; Anti-Arrhythmia Agents; Antidepressive Agents, Second-Generation; Citalopram; Drug Overdose;

2008
Prolonged QTc interval in a 14-year-old girl with escitalopram overdose.
    Journal of child and adolescent psychopharmacology, 2008, Volume: 18, Issue:3

    Topics: Adolescent; Citalopram; Drug Overdose; Female; Humans; Long QT Syndrome

2008
Corrected QT interval prolongation after an overdose of escitalopram, morphine, oxycodone, zopiclone and benzodiazepines.
    The Canadian journal of cardiology, 2008, Volume: 24, Issue:7

    Topics: Antidepressive Agents, Second-Generation; Arrhythmias, Cardiac; Azabicyclo Compounds; Benzodiazepine

2008
Predictive factors for generalized seizures after deliberate citalopram overdose.
    British journal of clinical pharmacology, 2008, Volume: 66, Issue:6

    Topics: Adult; Antidepressive Agents, Tricyclic; Citalopram; Cyclohexanols; Drug Interactions; Drug Overdose

2008
Understanding of poisonings and over-doses.
    Human & experimental toxicology, 2008, Volume: 27, Issue:10

    Topics: Age Factors; Child; Child, Preschool; Citalopram; Dose-Response Relationship, Drug; Drug Overdose; H

2008
Severe hypoglycaemia in citalopram overdose.
    European journal of emergency medicine : official journal of the European Society for Emergency Medicine, 2008, Volume: 15, Issue:4

    Topics: Adult; Citalopram; Drug Overdose; Female; Humans; Hypoglycemia; Selective Serotonin Reuptake Inhibit

2008
Comparison of toxicity of acute overdoses with citalopram and escitalopram.
    The Journal of emergency medicine, 2010, Volume: 39, Issue:1

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Child; Child, Preschool; Citalopram; Drug Overdose; Fema

2010
Neuroleptic malignant syndrome developing after acute overdose with olanzapine and chlorpromazine.
    Journal of medical toxicology : official journal of the American College of Medical Toxicology, 2009, Volume: 5, Issue:1

    Topics: Adult; Antipsychotic Agents; Benzodiazepines; Bromocriptine; Chlorpromazine; Citalopram; Combined Mo

2009
High dose insulin in toxic cardiogenic shock.
    Clinical toxicology (Philadelphia, Pa.), 2009, Volume: 47, Issue:4

    Topics: Aged; Amitriptyline; Antidepressive Agents, Second-Generation; Antidepressive Agents, Tricyclic; Car

2009
Clinical and ECG effects of escitalopram overdose.
    Annals of emergency medicine, 2009, Volume: 54, Issue:3

    Topics: Adolescent; Adult; Arrhythmias, Cardiac; Citalopram; Dose-Response Relationship, Drug; Drug Interact

2009
Escitalopram causes fewer seizures in human overdose than citalopram.
    Clinical toxicology (Philadelphia, Pa.), 2010, Volume: 48, Issue:3

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Austria; Citalopram; Drug Overdose; Female; Germany; Hum

2010
Metabolic acidosis and generalized seizures secondary to citalopram overdose: a case report.
    Journal of clinical pharmacy and therapeutics, 2010, Volume: 35, Issue:4

    Topics: Acidosis; Anticonvulsants; Citalopram; Depression; Drug Overdose; Female; Humans; Lorazepam; Seizure

2010
Evaluation of a QT nomogram for risk assessment after antidepressant overdose.
    British journal of clinical pharmacology, 2010, Volume: 70, Issue:6

    Topics: Adult; Antidepressive Agents; Citalopram; Cyclohexanols; Drug Overdose; Electrocardiography; Female;

2010
Prolonged QTc interval due to escitalopram overdose.
    Journal of the Mississippi State Medical Association, 2010, Volume: 51, Issue:12

    Topics: Adult; Citalopram; Depressive Disorder; Drug Overdose; Electrocardiography; Female; Humans; Long QT

2010
Drug monitoring of a case of citalopram overdosage.
    Drug and chemical toxicology, 2011, Volume: 34, Issue:4

    Topics: Citalopram; Drug Monitoring; Drug Overdose; Electrocardiography; Female; Half-Life; Humans; Long QT

2011
Population pharmacokinetics and pharmacodynamics of escitalopram in overdose and the effect of activated charcoal.
    British journal of clinical pharmacology, 2012, Volume: 73, Issue:3

    Topics: Adolescent; Adult; Area Under Curve; Bayes Theorem; Charcoal; Chromatography, Liquid; Citalopram; Do

2012
Delayed, fatal cardiotoxicity associated with bupropion and citalopram overdose.
    Journal of clinical psychopharmacology, 2012, Volume: 32, Issue:3

    Topics: Adult; Antidepressive Agents, Second-Generation; Bupropion; Cardiotoxins; Citalopram; Delayed-Action

2012
Monomorphic ventricular tachycardia after intentional citalopram overdose.
    The American journal of emergency medicine, 2013, Volume: 31, Issue:2

    Topics: Citalopram; Drug Overdose; Electrocardiography; Humans; Male; Selective Serotonin Reuptake Inhibitor

2013
Focal parietal necrosis of the sigmoid due to atypical neuroleptics: a case report.
    Acta gastro-enterologica Belgica, 2012, Volume: 75, Issue:2

    Topics: Adult; Anti-Anxiety Agents; Anticonvulsants; Antidepressive Agents; Antipsychotic Agents; Citalopram

2012
The pathogenetic role of adulterants in 5 cases of drug addicts with a fatal outcome.
    Forensic science international, 2013, Apr-10, Volume: 227, Issue:1-3

    Topics: Adult; Anesthetics, Local; Antitussive Agents; Bile; Brain Chemistry; Caffeine; Central Nervous Syst

2013
Polydrug fatality involving metaxalone.
    Journal of forensic sciences, 2003, Volume: 48, Issue:2

    Topics: Adult; Chlorpheniramine; Citalopram; Drug Overdose; Ethanol; Fatal Outcome; Female; Forensic Medicin

2003
Adult respiratory distress syndrome and renal failure associated with citalopram overdose.
    Human & experimental toxicology, 2003, Volume: 22, Issue:2

    Topics: Citalopram; Drug Overdose; Humans; Male; Middle Aged; Poisoning; Renal Insufficiency; Respiratory Di

2003
Cardiotoxicity and late onset seizures with citalopram overdose.
    The Journal of emergency medicine, 2003, Volume: 25, Issue:2

    Topics: Adult; Citalopram; Drug Overdose; Electrocardiography; Humans; Male; Seizures; Selective Serotonin R

2003
Fatal overdose of the herbicide bentazone.
    Forensic science international, 2003, Aug-27, Volume: 135, Issue:3

    Topics: Acetoacetates; Acetone; Benzothiadiazines; Central Nervous System Depressants; Citalopram; Drug Over

2003
Seizure secondary to citalopram overdose.
    The Journal of emergency medicine, 2004, Volume: 26, Issue:2

    Topics: Adenosine; Adult; Anti-Arrhythmia Agents; Anticonvulsants; Antidepressive Agents, Second-Generation;

2004
Are selective serotonin re-uptake inhibitors associated with an increased risk of self-harm by antidepressant overdose?
    European journal of clinical pharmacology, 2004, Volume: 60, Issue:3

    Topics: Adult; Amitriptyline; Antidepressive Agents, Tricyclic; Citalopram; Cyclohexanols; Doxepin; Drug Ove

2004
Comparative toxicity of citalopram and the newer antidepressants after overdose.
    Journal of toxicology. Clinical toxicology, 2004, Volume: 42, Issue:1

    Topics: Administration, Oral; Adult; Antidepressive Agents, Second-Generation; Citalopram; Cyclohexanols; Dr

2004
Reversal of citalopram-induced junctional bradycardia with intravenous sodium bicarbonate.
    Pharmacotherapy, 2005, Volume: 25, Issue:1

    Topics: Aged; Aged, 80 and over; Arrhythmia, Sinus; Bradycardia; Citalopram; Depression; Drug Overdose; Elec

2005
Causal or casual?
    Pharmacoepidemiology and drug safety, 2005, Volume: 14, Issue:6

    Topics: Antidepressive Agents, Second-Generation; Citalopram; Cyclohexanols; Drug Overdose; Fluoxetine; Huma

2005
Postmortem tissue distribution of olanzapine and citalopram in a drug intoxication.
    Journal of forensic sciences, 2005, Volume: 50, Issue:3

    Topics: Adult; Antidepressive Agents, Second-Generation; Antipsychotic Agents; Autopsy; Benzodiazepines; Cit

2005
Citalopram associated with acute angle-closure glaucoma: case report.
    BMC ophthalmology, 2005, Oct-04, Volume: 5

    Topics: Acute Disease; Antidepressive Agents, Second-Generation; Citalopram; Drug Overdose; Female; Glaucoma

2005
Interferon beta-1a overdose in a multiple sclerosis patient.
    The Annals of pharmacotherapy, 2005, Volume: 39, Issue:11

    Topics: Adult; Antidepressive Agents; Citalopram; Depression; Depressive Disorder; Drug Overdose; Emergencie

2005
Pharmacokinetic-pharmacodynamic modelling of QT interval prolongation following citalopram overdoses.
    British journal of clinical pharmacology, 2006, Volume: 61, Issue:2

    Topics: Adolescent; Adult; Age Distribution; Aged; Antidepressive Agents, Second-Generation; Charcoal; Cital

2006
Outcomes after supratherapeutic escitalopram ingestions.
    The Journal of emergency medicine, 2006, Volume: 30, Issue:1

    Topics: Adolescent; Adult; Aged; Arizona; Child; Child, Preschool; Citalopram; Drug Overdose; Emergency Serv

2006
[Citalopram overdose poisoning in QTc interval prolongation].
    Duodecim; laaketieteellinen aikakauskirja, 2006, Volume: 122, Issue:1

    Topics: Adolescent; Citalopram; Drug Overdose; Electrocardiography; Female; Finland; Follow-Up Studies; Huma

2006
Clinical course and toxicokinetic data following isolated citalopram overdose in an infant.
    Clinical toxicology (Philadelphia, Pa.), 2006, Volume: 44, Issue:2

    Topics: Charcoal; Citalopram; Drug Overdose; Female; Humans; Hypnotics and Sedatives; Infant; Intensive Care

2006
Application of pharmacokinetic-pharmacodynamic modelling in management of QT abnormalities after citalopram overdose.
    Intensive care medicine, 2006, Volume: 32, Issue:7

    Topics: Adolescent; Adult; Aged; Charcoal; Citalopram; Computer Simulation; Drug Overdose; Female; Guideline

2006
Digitalis intoxication induced by paroxetine co-administration.
    Lancet (London, England), 2006, Dec-02, Volume: 368, Issue:9551

    Topics: Aged; Cardiovascular System; Citalopram; Cyclohexanols; Digoxin; Drug Interactions; Drug Overdose; F

2006
In response to Isbister et al.: Application of pharmacokinetic-pharmacodynamic modeling in management of QT abnormalities after citalopram overdose.
    Intensive care medicine, 2007, Volume: 33, Issue:4

    Topics: Algorithms; Citalopram; Computer Simulation; Drug Overdose; Humans; Selective Serotonin Reuptake Inh

2007
Activated charcoal decreases the risk of QT prolongation after citalopram overdose.
    Annals of emergency medicine, 2007, Volume: 50, Issue:5

    Topics: Adult; Charcoal; Citalopram; Databases, Factual; Drug Overdose; Female; Humans; Long QT Syndrome; Ma

2007
Five fatal cases of serotonin syndrome after moclobemide-citalopram or moclobemide-clomipramine overdoses.
    Lancet (London, England), 1993, Dec-04, Volume: 342, Issue:8884

    Topics: Adult; Benzamides; Citalopram; Clomipramine; Drug Interactions; Drug Overdose; Fatal Outcome; Female

1993
Fatal overdose with citalopram.
    Lancet (London, England), 1996, Aug-03, Volume: 348, Issue:9023

    Topics: Adult; Citalopram; Drug Overdose; Female; Humans; Male; Middle Aged; Selective Serotonin Reuptake In

1996
Risks with citalopram in perspective.
    Lancet (London, England), 1996, Oct-12, Volume: 348, Issue:9033

    Topics: Antidepressive Agents; Citalopram; Depression; Drug Overdose; Humans; Risk Factors; Selective Seroto

1996
Citalopram overdose--review of cases treated in Swedish hospitals.
    Journal of toxicology. Clinical toxicology, 1997, Volume: 35, Issue:3

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Citalopram; Dose-Response Relationship, Drug; Drug Inter

1997
Symptoms and signs of severe citalopram overdose.
    Lancet (London, England), 1997, May-31, Volume: 349, Issue:9065

    Topics: Adult; Antidepressive Agents; Charcoal; Citalopram; Drug Overdose; Electrocardiography; Female; Gast

1997
[Picture of poisoning in citalopram overdose. Convulsions and ECG symptoms can occur].
    Lakartidningen, 1997, Apr-23, Volume: 94, Issue:17

    Topics: Adolescent; Adult; Aged; Antidepressive Agents; Citalopram; Drug Interactions; Drug Overdose; Electr

1997
Citalopram toxicity.
    Lancet (London, England), 1997, Sep-13, Volume: 350, Issue:9080

    Topics: Antidepressive Agents; Citalopram; Drug Overdose; Humans; Seizures; Selective Serotonin Reuptake Inh

1997
Drug treatment of depression. Citalopram in overdose may result in serious morbidity and death.
    BMJ (Clinical research ed.), 1998, Jan-24, Volume: 316, Issue:7127

    Topics: Antidepressive Agents; Citalopram; Depressive Disorder; Drug Overdose; Humans; Selective Serotonin R

1998
Citalopram is safe.
    BMJ (Clinical research ed.), 1998, Jun-13, Volume: 316, Issue:7147

    Topics: Citalopram; Drug Overdose; Humans; Selective Serotonin Reuptake Inhibitors; Sweden

1998
Citalopram concentrations in samples from autopsies and living persons.
    International journal of legal medicine, 1998, Volume: 111, Issue:4

    Topics: Adult; Aged; Aged, 80 and over; Autopsy; Citalopram; Denmark; Drug Overdose; Female; Humans; Male; M

1998
Fatality caused by a combined trimipramine-citalopram intoxication.
    Forensic science international, 1999, Dec-06, Volume: 106, Issue:2

    Topics: Antidepressive Agents, Second-Generation; Antidepressive Agents, Tricyclic; Citalopram; Depression;

1999
Neuroleptic malignant syndrome due to citalopram overdose.
    Canadian journal of psychiatry. Revue canadienne de psychiatrie, 2000, Volume: 45, Issue:10

    Topics: Adult; Citalopram; Drug Overdose; Humans; Male; Neuroleptic Malignant Syndrome; Suicide, Attempted

2000
Citalopram overdose, serotonin toxicity, or neuroleptic malignant syndrome?
    Canadian journal of psychiatry. Revue canadienne de psychiatrie, 2001, Volume: 46, Issue:7

    Topics: Antidepressive Agents; Citalopram; Depressive Disorder; Diagnosis, Differential; Drug Overdose; Huma

2001
Case report: left bundle branch block--a rare complication of citalopram overdose.
    Journal of the South Carolina Medical Association (1975), 2001, Volume: 97, Issue:9

    Topics: Adult; Bundle-Branch Block; Citalopram; Drug Overdose; Female; Humans; Pregnancy; Selective Serotoni

2001