citalopram has been researched along with Delayed Effects, Prenatal Exposure in 28 studies
Citalopram: A furancarbonitrile that is one of the serotonin uptake inhibitors used as an antidepressant. The drug is also effective in reducing ethanol uptake in alcoholics and is used in depressed patients who also suffer from TARDIVE DYSKINESIA in preference to tricyclic antidepressants, which aggravate dyskinesia.
citalopram : A racemate comprising equimolar amounts of (R)-citalopram and its enantiomer, escitalopram. It is used as an antidepressant, although only escitalopram is active.
1-[3-(dimethylamino)propyl]-1-(4-fluorophenyl)-1,3-dihydro-2-benzofuran-5-carbonitrile : A nitrile that is 1,3-dihydro-2-benzofuran-5-carbonitrile in which one of the hydrogens at position 1 is replaced by a p-fluorophenyl group, while the other is replaced by a 3-(dimethylamino)propyl group.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Treatment of major depression disorder with Selective serotonin reuptake inhibitors (SSRIs), such as citalopram (CTM), during pregnancy effects on the neurological trajectory of the offspring and induces enduring consequences, notably emotional and cognitive impairment." | 8.12 | Prenatal exposure of citalopram elicits depression-like and anxiety-like behaviors and alteration of morphology and protein expression of medial prefrontal cortex in young adult mice. ( Butt, MU; Du, L; Jia, M; Wang, Q; Wang, Y; Wu, J; Zahra, A, 2022) |
| "Neonatal abstinence syndrome (NAS) due to prenatally exposure to citalopram can develop during the first days of life even with low dose of drug exposure." | 7.85 | Neonatal abstinence syndrome due to prenatally citalopram exposure: A case report. ( Bas, AY; Celik, IH; Demirel, N; Erol, S; Ozcan, B, 2017) |
| "A term neonate presenting with necrotizing enterocolitis following in utero and breast milk exposure to the newest serotonin selective reuptake inhibitor, escitalopram, is described." | 7.74 | Necrotizing enterocolitis associated with in utero and breast milk exposure to the selective serotonin reuptake inhibitor, escitalopram. ( Carter, BS; Potts, AL; Shenai, JP; Young, KL, 2007) |
| "Treatment of major depression disorder with Selective serotonin reuptake inhibitors (SSRIs), such as citalopram (CTM), during pregnancy effects on the neurological trajectory of the offspring and induces enduring consequences, notably emotional and cognitive impairment." | 4.12 | Prenatal exposure of citalopram elicits depression-like and anxiety-like behaviors and alteration of morphology and protein expression of medial prefrontal cortex in young adult mice. ( Butt, MU; Du, L; Jia, M; Wang, Q; Wang, Y; Wu, J; Zahra, A, 2022) |
| "Citalopram (CTM), a selective serotonin reuptake inhibitor (SSRI), has been widely used to treat panic disorders, such as depression which is one of the most disabling, yet common, psychiatric disorders." | 3.91 | Exposure to prenatal antidepressant alters medial prefrontal-striatal synchronization in mice. ( Chen, Y; Jiang, J; Long, C; Yang, L; Zahra, A; Zheng, Y, 2019) |
| "Neonatal abstinence syndrome (NAS) due to prenatally exposure to citalopram can develop during the first days of life even with low dose of drug exposure." | 3.85 | Neonatal abstinence syndrome due to prenatally citalopram exposure: A case report. ( Bas, AY; Celik, IH; Demirel, N; Erol, S; Ozcan, B, 2017) |
| " Despite extended residual persistence of dichlorodiphenyltrichloroethane (DDT) in the environment, the mechanisms of perinatal actions of DDT that could account for adult-onset of depression are largely unknown." | 3.85 | Depressive-like effect of prenatal exposure to DDT involves global DNA hypomethylation and impairment of GPER1/ESR1 protein levels but not ESR2 and AHR/ARNT signaling. ( Grochowalski, A; Kajta, M; Lason, W; Litwa, E; Nalepa, I; Rogóż, Z; Rzemieniec, J; Wnuk, A; Wojtowicz, AK; Zelek-Molik, A, 2017) |
| "The objective of the current study is to determine whether the increased anxiety of prenatally stressed (PS) rats of both sexes is associated with changes in 5HT1A and CRF type 2 receptors (5HT1AR and CRFR2) in the prefrontal cortex (PFC)-dorsal raphe nuclei (DRN) axis, and how these are affected by chronic treatment with citalopram (10 mg/kg/day)." | 3.81 | Sex dependent reduction by prenatal stress of the expression of 5HT1A receptors in the prefrontal cortex and CRF type 2 receptors in the raphe nucleus in rats: reversal by citalopram. ( Dosoretz-Abittan, L; Shoham, S; Weinstock, M; Zohar, I, 2015) |
| "Our results provide confirmatory evidence that citalopram exposure is associated with cellular and morphological alterations of the craniofacial complex, which may have important implications for use during pregnancy." | 3.80 | Selective serotonin reuptake inhibitor exposure alters osteoblast gene expression and craniofacial development in mice. ( Cray, JJ; Elsalanty, M; Howie, RN; Parsons, TE; Weinberg, SM; Yu, JC, 2014) |
| " We examined whether treatment with a selective serotonin reuptake inhibitor [escitalopram (ESC)] could downregulate HPA axis activity and restore insulin sensitivity in LBW rats." | 3.76 | Treatment with an SSRI antidepressant restores hippocampo-hypothalamic corticosteroid feedback and reverses insulin resistance in low-birth-weight rats. ( Buhl, CS; Buhl, ES; Elfving, B; Jensen, TK; Jessen, N; Kristiansen, SB; Lund, S; Petersen, KF; Pold, R; Schmitz, O; Solskov, L; Wegener, G, 2010) |
| "A term neonate presenting with necrotizing enterocolitis following in utero and breast milk exposure to the newest serotonin selective reuptake inhibitor, escitalopram, is described." | 3.74 | Necrotizing enterocolitis associated with in utero and breast milk exposure to the selective serotonin reuptake inhibitor, escitalopram. ( Carter, BS; Potts, AL; Shenai, JP; Young, KL, 2007) |
| "Depression during pregnancy has been linked to in utero stress and is associated with long-lasting symptoms in offspring, including anxiety, helplessness, attentional deficits, and social withdrawal." | 1.42 | Prenatal stress, regardless of concurrent escitalopram treatment, alters behavior and amygdala gene expression of adolescent female rats. ( Bourke, CH; Ehrlich, DE; Hazra, R; Jairam, N; Neigh, GN; Nemeth, CL; Owens, MJ; Rainnie, DG; Rowson, S; Ryan, SJ; Sholar, CA; Stowe, ZN, 2015) |
| "We suggest the hypothesis that neonatal withdrawal syndrome may follow citalopram serotonin toxicity." | 1.39 | Neonatal toxicity following maternal citalopram treatment. ( Bonati, M; Butera, R; Cotti Cottini, F; Eleftheriou, G; Farina, M, 2013) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 3 (10.71) | 18.2507 |
| 2000's | 5 (17.86) | 29.6817 |
| 2010's | 16 (57.14) | 24.3611 |
| 2020's | 4 (14.29) | 2.80 |
| Authors | Studies |
|---|---|
| Marks, C | 1 |
| Silvola, R | 1 |
| Teal, E | 1 |
| Quinney, SK | 1 |
| Haas, DM | 1 |
| Zahra, A | 3 |
| Du, L | 1 |
| Jia, M | 1 |
| Butt, MU | 1 |
| Wang, Q | 1 |
| Wang, Y | 1 |
| Wu, J | 1 |
| Olstad, EW | 1 |
| Nordeng, HME | 1 |
| Sandve, GK | 1 |
| Lyle, R | 1 |
| Gervin, K | 1 |
| Burstein, O | 1 |
| Simon, N | 1 |
| Simchon-Tenenbaum, Y | 1 |
| Rehavi, M | 1 |
| Franko, M | 1 |
| Shamir, A | 1 |
| Doron, R | 1 |
| Nagano, R | 1 |
| Nagano, M | 1 |
| Nakai, A | 1 |
| Takeshita, T | 1 |
| Suzuki, H | 1 |
| Erol, S | 1 |
| Ozcan, B | 1 |
| Celik, IH | 1 |
| Bas, AY | 1 |
| Demirel, N | 1 |
| Jwa, S | 1 |
| Wada, Y | 1 |
| Yamamoto, M | 1 |
| Sumida, Y | 1 |
| Jiang, J | 2 |
| Chen, Y | 2 |
| Long, C | 2 |
| Yang, L | 2 |
| Zheng, Y | 1 |
| Eleftheriou, G | 1 |
| Butera, R | 1 |
| Cotti Cottini, F | 1 |
| Bonati, M | 1 |
| Farina, M | 1 |
| Rodgers, AB | 1 |
| Morgan, CP | 1 |
| Bronson, SL | 1 |
| Revello, S | 1 |
| Bale, TL | 1 |
| Cray, JJ | 1 |
| Weinberg, SM | 1 |
| Parsons, TE | 1 |
| Howie, RN | 1 |
| Elsalanty, M | 1 |
| Yu, JC | 1 |
| Zohar, I | 1 |
| Dosoretz-Abittan, L | 1 |
| Shoham, S | 1 |
| Weinstock, M | 1 |
| Ehrlich, DE | 1 |
| Neigh, GN | 2 |
| Bourke, CH | 1 |
| Nemeth, CL | 2 |
| Hazra, R | 1 |
| Ryan, SJ | 1 |
| Rowson, S | 1 |
| Jairam, N | 1 |
| Sholar, CA | 1 |
| Rainnie, DG | 1 |
| Stowe, ZN | 2 |
| Owens, MJ | 2 |
| Velasquez, JC | 1 |
| Goeden, N | 1 |
| Herod, SM | 1 |
| Bonnin, A | 1 |
| Kelly, SD | 1 |
| Hardy, EE | 1 |
| Bourke, C | 1 |
| Sprowles, JL | 1 |
| Hufgard, JR | 1 |
| Gutierrez, A | 1 |
| Bailey, RA | 1 |
| Jablonski, SA | 1 |
| Williams, MT | 1 |
| Vorhees, CV | 1 |
| Kajta, M | 1 |
| Wnuk, A | 1 |
| Rzemieniec, J | 1 |
| Litwa, E | 1 |
| Lason, W | 1 |
| Zelek-Molik, A | 1 |
| Nalepa, I | 1 |
| Rogóż, Z | 1 |
| Grochowalski, A | 1 |
| Wojtowicz, AK | 1 |
| Gentile, S | 1 |
| Buhl, ES | 1 |
| Jensen, TK | 1 |
| Jessen, N | 1 |
| Elfving, B | 1 |
| Buhl, CS | 1 |
| Kristiansen, SB | 1 |
| Pold, R | 1 |
| Solskov, L | 1 |
| Schmitz, O | 1 |
| Wegener, G | 1 |
| Lund, S | 1 |
| Petersen, KF | 1 |
| Weaver, KJ | 1 |
| Paul, IA | 1 |
| Lin, RC | 1 |
| Simpson, KL | 1 |
| Hsiao, SY | 1 |
| Cherng, CF | 1 |
| Yang, YK | 1 |
| Yeh, TL | 1 |
| Yu, L | 1 |
| Potts, AL | 1 |
| Young, KL | 1 |
| Carter, BS | 1 |
| Shenai, JP | 1 |
| Kwon, P | 1 |
| Lefkowitz, W | 1 |
| Blatt, GJ | 1 |
| Chen, JC | 1 |
| Rosene, DL | 1 |
| Volicer, L | 1 |
| Galler, JR | 1 |
| Cabrera, TM | 1 |
| Levy, AD | 1 |
| Li, Q | 1 |
| van de Kar, LD | 1 |
| Battaglia, G | 1 |
| Kim, JA | 1 |
| Druse, MJ | 1 |
| Yan, QS | 1 |
1 trial available for citalopram and Delayed Effects, Prenatal Exposure
| Article | Year |
|---|---|
Paternal stress exposure alters sperm microRNA content and reprograms offspring HPA stress axis regulation.
Topics: Acoustic Stimulation; Adaptation, Ocular; Analysis of Variance; Animals; Animals, Newborn; Citalopra | 2013 |
27 other studies available for citalopram and Delayed Effects, Prenatal Exposure
| Article | Year |
|---|---|
Comparing newborn outcomes after prenatal exposure to individual antidepressants: A retrospective cohort study.
Topics: Antidepressive Agents; Bupropion; Citalopram; Duloxetine Hydrochloride; Escitalopram; Female; Fluoxe | 2021 |
Prenatal exposure of citalopram elicits depression-like and anxiety-like behaviors and alteration of morphology and protein expression of medial prefrontal cortex in young adult mice.
Topics: Animals; Anxiety; Citalopram; Depression; Depressive Disorder, Major; Female; Male; Mice; Mice, Inbr | 2022 |
Effects of prenatal exposure to (es)citalopram and maternal depression during pregnancy on DNA methylation and child neurodevelopment.
Topics: Child; Citalopram; Cohort Studies; Depression; DNA Methylation; Female; Humans; Infant, Newborn; Pre | 2023 |
Moderation of the transgenerational transference of antenatal stress-induced anxiety.
Topics: Animals; Anxiety; Citalopram; COVID-19; Crataegus; Disease Models, Animal; Drugs, Chinese Herbal; Fe | 2021 |
Differential effects of neonatal SSRI treatments on hypoxia-induced behavioral changes in male and female offspring.
Topics: Animals; Animals, Newborn; Behavior, Animal; Citalopram; Disease Models, Animal; Female; Fluoxetine; | 2017 |
Neonatal abstinence syndrome due to prenatally citalopram exposure: A case report.
Topics: Anticonvulsants; Antidepressive Agents, Second-Generation; Citalopram; Depressive Disorder, Major; F | 2017 |
Neonatal morbidity due to maternal use of two antidepressant drugs.
Topics: Anti-Anxiety Agents; Antidepressive Agents; Benzodiazepines; Citalopram; Drug Therapy, Combination; | 2018 |
Memantine rescues prenatal citalopram exposure-induced striatal and social abnormalities in mice.
Topics: Animals; Antidepressive Agents, Second-Generation; Anxiety; Citalopram; Corpus Striatum; Excitatory | 2018 |
Exposure to prenatal antidepressant alters medial prefrontal-striatal synchronization in mice.
Topics: Animals; Antidepressive Agents; Anxiety; Brain; Citalopram; Corpus Striatum; Dendrites; Depression; | 2019 |
Neonatal toxicity following maternal citalopram treatment.
Topics: Citalopram; Depressive Disorder, Major; Diagnosis, Differential; Female; Half-Life; Humans; Infant, | 2013 |
Selective serotonin reuptake inhibitor exposure alters osteoblast gene expression and craniofacial development in mice.
Topics: Animals; Biomarkers; Cells, Cultured; Citalopram; Craniofacial Abnormalities; Female; Gene Expressio | 2014 |
Sex dependent reduction by prenatal stress of the expression of 5HT1A receptors in the prefrontal cortex and CRF type 2 receptors in the raphe nucleus in rats: reversal by citalopram.
Topics: Animals; Anxiety; Citalopram; Corticotropin-Releasing Hormone; Dorsal Raphe Nucleus; Female; GABAerg | 2015 |
Prenatal stress, regardless of concurrent escitalopram treatment, alters behavior and amygdala gene expression of adolescent female rats.
Topics: Amygdala; Animals; Anxiety; Citalopram; Corticosterone; Disease Models, Animal; Estradiol; Female; g | 2015 |
Maternal Pharmacokinetics and Fetal Disposition of (±)-Citalopram during Mouse Pregnancy.
Topics: Animals; Chromatography, High Pressure Liquid; Citalopram; Female; Fetus; Mice; Pregnancy; Prenatal | 2016 |
Prenatal stress-induced increases in hippocampal von Willebrand factor expression are prevented by concurrent prenatal escitalopram.
Topics: Age Factors; Amygdala; Angiogenic Proteins; Animals; Citalopram; Female; Hippocampus; Male; Prefront | 2017 |
Perinatal exposure to the selective serotonin reuptake inhibitor citalopram alters spatial learning and memory, anxiety, depression, and startle in Sprague-Dawley rats.
Topics: Age Factors; Amphetamines; Animals; Animals, Newborn; Anxiety; Body Weight; Citalopram; Depression; | 2016 |
Depressive-like effect of prenatal exposure to DDT involves global DNA hypomethylation and impairment of GPER1/ESR1 protein levels but not ESR2 and AHR/ARNT signaling.
Topics: Animals; Antidepressive Agents, Second-Generation; Behavior, Animal; Brain; Citalopram; DDT; Depress | 2017 |
Use of escitalopram during pregnancy: navigating towards international guidelines and the real world.
Topics: Adult; Citalopram; Female; Fetus; Humans; Infant, Newborn; International Cooperation; Lactation; Liv | 2008 |
Treatment with an SSRI antidepressant restores hippocampo-hypothalamic corticosteroid feedback and reverses insulin resistance in low-birth-weight rats.
Topics: Adrenocorticotropic Hormone; Analysis of Variance; Animals; Area Under Curve; Blood Glucose; Body We | 2010 |
Neonatal exposure to citalopram selectively alters the expression of the serotonin transporter in the hippocampus: dose-dependent effects.
Topics: Animals; Animals, Newborn; Caudate Nucleus; Cerebral Cortex; Citalopram; Cognition; Dose-Response Re | 2010 |
Prenatal bupropion exposure enhances the cocaine reward and stress susceptibility in adult mice.
Topics: Animals; Antidepressive Agents, Second-Generation; Anxiety; Bupropion; Citalopram; Cocaine; Conditio | 2005 |
Necrotizing enterocolitis associated with in utero and breast milk exposure to the selective serotonin reuptake inhibitor, escitalopram.
Topics: Citalopram; Enterocolitis, Necrotizing; Female; Humans; Infant, Newborn; Milk, Human; Pregnancy; Pre | 2007 |
Neonatal extrapyramidal movements. Neonatal withdrawal due to maternal citalopram and ondansetron use.
Topics: Adult; Anti-Anxiety Agents; Basal Ganglia Diseases; Citalopram; Female; Humans; Infant, Newborn; Lor | 2008 |
Prenatal protein malnutrition effects on the serotonergic system in the hippocampal formation: an immunocytochemical, ligand binding, and neurochemical study.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Chromatography, High Pressure Liquid; Citalopram; F | 1994 |
Prenatal methamphetamine attenuates serotonin mediated renin secretion in male and female rat progeny: evidence for selective long-term dysfunction of serotonin pathways in brain.
Topics: Analysis of Variance; Animals; Body Weight; Brain; Cerebral Cortex; Citalopram; Female; Hypothalamus | 1993 |
Protective effects of maternal buspirone treatment on serotonin reuptake sites in ethanol-exposed offspring.
Topics: Animals; Autoradiography; Brain; Brain Chemistry; Buspirone; Central Nervous System Depressants; Cit | 1996 |
Reduced serotonin release and serotonin uptake sites in the rat nucleus accumbens and striatum after prenatal cocaine exposure.
Topics: Animals; Animals, Newborn; Citalopram; Cocaine; Cocaine-Related Disorders; Electric Stimulation; Fem | 2002 |