citalopram has been researched along with Complications, Pregnancy in 22 studies
Citalopram: A furancarbonitrile that is one of the serotonin uptake inhibitors used as an antidepressant. The drug is also effective in reducing ethanol uptake in alcoholics and is used in depressed patients who also suffer from TARDIVE DYSKINESIA in preference to tricyclic antidepressants, which aggravate dyskinesia.
citalopram : A racemate comprising equimolar amounts of (R)-citalopram and its enantiomer, escitalopram. It is used as an antidepressant, although only escitalopram is active.
1-[3-(dimethylamino)propyl]-1-(4-fluorophenyl)-1,3-dihydro-2-benzofuran-5-carbonitrile : A nitrile that is 1,3-dihydro-2-benzofuran-5-carbonitrile in which one of the hydrogens at position 1 is replaced by a p-fluorophenyl group, while the other is replaced by a 3-(dimethylamino)propyl group.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Although citalopram has gained wide acceptance in the treatment of depression and anxiety disorders, its use during pregnancy and lactation has been poorly characterized." | 9.10 | Citalopram in pregnancy and lactation. ( Ekblad, S; Ekblad, U; Heikkinen, T; Kero, P; Laine, K, 2002) |
| "Neonatal abstinence syndrome (NAS) due to prenatally exposure to citalopram can develop during the first days of life even with low dose of drug exposure." | 7.85 | Neonatal abstinence syndrome due to prenatally citalopram exposure: A case report. ( Bas, AY; Celik, IH; Demirel, N; Erol, S; Ozcan, B, 2017) |
| "A term neonate presenting with necrotizing enterocolitis following in utero and breast milk exposure to the newest serotonin selective reuptake inhibitor, escitalopram, is described." | 7.74 | Necrotizing enterocolitis associated with in utero and breast milk exposure to the selective serotonin reuptake inhibitor, escitalopram. ( Carter, BS; Potts, AL; Shenai, JP; Young, KL, 2007) |
| "We describe the case of a pregnancy healthy outcome after in utero consecutive exposure to lamotrigine and citalopram." | 7.74 | Consecutive exposure to lamotrigine and citalopram during pregnancy. ( Gentile, S; Vozzi, F, 2007) |
| "Pregnant women who contacted the Motherisk Program, a Teratogen Information Center in Toronto, Ontario, with regard to the safety of citalopram in pregnancy were enrolled in the study." | 7.73 | Citalopram use in pregnancy: prospective comparative evaluation of pregnancy and fetal outcome. ( Einarson, A; Koren, G; Sarkissian, L; Shuhaiber, S; Sivojelezova, A, 2005) |
| "The median daily dosage of citalopram was 20mg (Q1: 10mg, Q3: 20mg; range 10-40mg)." | 5.46 | Pregnancy exposure to citalopram - Therapeutic drug monitoring in maternal blood, amniotic fluid and cord blood. ( Goecke, TW; Gründer, G; Janssen, G; Paulzen, M; Schoretsanitis, G; Stickeler, E; Stingl, JC, 2017) |
| "Bupropion's efficacy for smoking cessation in pregnant women is unknown." | 5.14 | The relationship between antidepressant use and smoking cessation in pregnant women in treatment for substance abuse. ( Brigham, EP; Chisolm, MS; Jones, HE; Strain, EC; Tuten, M, 2010) |
| " Across pregnancy and postpartum, the mean dose-corrected plasma concentrations (L/D ratios) of S- and R-citalopram and S-sertraline, and the corresponding primary chiral metabolites S- and R-desmethylcitalopram and N-desmethylsertra-line were assessed." | 5.13 | Changes in antidepressant metabolism and dosing across pregnancy and early postpartum. ( Helsel, JC; Perel, JM; Sit, DK; Wisner, KL, 2008) |
| "Although citalopram has gained wide acceptance in the treatment of depression and anxiety disorders, its use during pregnancy and lactation has been poorly characterized." | 5.10 | Citalopram in pregnancy and lactation. ( Ekblad, S; Ekblad, U; Heikkinen, T; Kero, P; Laine, K, 2002) |
| "Sertraline and citalopram should be first-line drug treatments for anxiety and depression in pregnant women in the SSRI class." | 4.95 | What are the risks associated with different Selective Serotonin Re-uptake Inhibitors (SSRIs) to treat depression and anxiety in pregnancy? An evaluation of current evidence. ( Agius, M; Ripullone, K; Womersley, K, 2017) |
| "Neonatal abstinence syndrome (NAS) due to prenatally exposure to citalopram can develop during the first days of life even with low dose of drug exposure." | 3.85 | Neonatal abstinence syndrome due to prenatally citalopram exposure: A case report. ( Bas, AY; Celik, IH; Demirel, N; Erol, S; Ozcan, B, 2017) |
| "A term neonate presenting with necrotizing enterocolitis following in utero and breast milk exposure to the newest serotonin selective reuptake inhibitor, escitalopram, is described." | 3.74 | Necrotizing enterocolitis associated with in utero and breast milk exposure to the selective serotonin reuptake inhibitor, escitalopram. ( Carter, BS; Potts, AL; Shenai, JP; Young, KL, 2007) |
| "We describe the case of a pregnancy healthy outcome after in utero consecutive exposure to lamotrigine and citalopram." | 3.74 | Consecutive exposure to lamotrigine and citalopram during pregnancy. ( Gentile, S; Vozzi, F, 2007) |
| "Pregnant women who contacted the Motherisk Program, a Teratogen Information Center in Toronto, Ontario, with regard to the safety of citalopram in pregnancy were enrolled in the study." | 3.73 | Citalopram use in pregnancy: prospective comparative evaluation of pregnancy and fetal outcome. ( Einarson, A; Koren, G; Sarkissian, L; Shuhaiber, S; Sivojelezova, A, 2005) |
| "We describe the first reported case of acute cholestasis due to citalopram (selective serotonin reuptake inhibitor) occurring in a patient who also experienced obstetric cholestasis in association with each of three pregnancies; in a second patient cholestasis developed due to dothiepin (tricyclic antidepressant), and six years later due to paroxetine." | 3.72 | Antidepressant induced cholestasis: hepatocellular redistribution of multidrug resistant protein (MRP2). ( Chilton, AP; Elias, E; Hubscher, SG; Milkiewicz, P, 2003) |
| "The median daily dosage of citalopram was 20mg (Q1: 10mg, Q3: 20mg; range 10-40mg)." | 1.46 | Pregnancy exposure to citalopram - Therapeutic drug monitoring in maternal blood, amniotic fluid and cord blood. ( Goecke, TW; Gründer, G; Janssen, G; Paulzen, M; Schoretsanitis, G; Stickeler, E; Stingl, JC, 2017) |
| "We suggest the hypothesis that neonatal withdrawal syndrome may follow citalopram serotonin toxicity." | 1.39 | Neonatal toxicity following maternal citalopram treatment. ( Bonati, M; Butera, R; Cotti Cottini, F; Eleftheriou, G; Farina, M, 2013) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (4.55) | 18.2507 |
| 2000's | 12 (54.55) | 29.6817 |
| 2010's | 9 (40.91) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Paulzen, M | 1 |
| Goecke, TW | 1 |
| Stingl, JC | 1 |
| Janssen, G | 1 |
| Stickeler, E | 1 |
| Gründer, G | 1 |
| Schoretsanitis, G | 1 |
| Womersley, K | 1 |
| Ripullone, K | 1 |
| Agius, M | 1 |
| Erol, S | 1 |
| Ozcan, B | 1 |
| Celik, IH | 1 |
| Bas, AY | 1 |
| Demirel, N | 1 |
| Jwa, S | 1 |
| Wada, Y | 1 |
| Yamamoto, M | 1 |
| Sumida, Y | 1 |
| Eleftheriou, G | 1 |
| Butera, R | 1 |
| Cotti Cottini, F | 1 |
| Bonati, M | 1 |
| Farina, M | 1 |
| Kouros, N | 1 |
| Gentile, S | 2 |
| Tixier, H | 1 |
| Feyeux, C | 1 |
| Girod, S | 1 |
| Thouvenot, S | 1 |
| Morisse, M | 1 |
| Douvier, S | 1 |
| Sagot, P | 1 |
| Werremeyer, A | 1 |
| Chisolm, MS | 1 |
| Brigham, EP | 1 |
| Tuten, M | 1 |
| Strain, EC | 1 |
| Jones, HE | 1 |
| Tuccori, M | 1 |
| Montagnani, S | 1 |
| Testi, A | 1 |
| Ruggiero, E | 1 |
| Mantarro, S | 1 |
| Scollo, C | 1 |
| Pergola, A | 1 |
| Fornai, M | 1 |
| Antonioli, L | 1 |
| Colucci, R | 1 |
| Corona, T | 1 |
| Blandizzi, C | 1 |
| Patel, BN | 1 |
| Beste, J | 1 |
| Blackwell, JC | 1 |
| Heikkinen, T | 1 |
| Ekblad, U | 1 |
| Kero, P | 1 |
| Ekblad, S | 1 |
| Laine, K | 1 |
| Milkiewicz, P | 1 |
| Chilton, AP | 1 |
| Hubscher, SG | 1 |
| Elias, E | 1 |
| Hendrick, V | 1 |
| Stowe, ZN | 1 |
| Altshuler, LL | 1 |
| Hwang, S | 1 |
| Lee, E | 1 |
| Haynes, D | 1 |
| Wu, CC | 1 |
| Chen, JY | 1 |
| Tao, PL | 1 |
| Chen, YA | 1 |
| Yeh, GC | 1 |
| Sivojelezova, A | 1 |
| Shuhaiber, S | 1 |
| Sarkissian, L | 1 |
| Einarson, A | 1 |
| Koren, G | 1 |
| Potts, AL | 1 |
| Young, KL | 1 |
| Carter, BS | 1 |
| Shenai, JP | 1 |
| Vozzi, F | 1 |
| Sit, DK | 1 |
| Perel, JM | 1 |
| Helsel, JC | 1 |
| Wisner, KL | 1 |
| Seifritz, E | 1 |
| Holsboer-Trachsler, E | 1 |
| Haberthur, F | 1 |
| Hemmeter, U | 1 |
| Pöldinger, W | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Antidepressant Use During Pregnancy[NCT00279370] | 283 participants (Actual) | Observational | 1999-09-30 | Completed | |||
| A Prospective Study of Pregnant and Postpartum Women With and Without Mood Disorders[NCT03615794] | 400 participants (Anticipated) | Observational | 2017-10-01 | Recruiting | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
2 reviews available for citalopram and Complications, Pregnancy
| Article | Year |
|---|---|
What are the risks associated with different Selective Serotonin Re-uptake Inhibitors (SSRIs) to treat depression and anxiety in pregnancy? An evaluation of current evidence.
Topics: Adult; Anxiety; Citalopram; Depression; Female; Humans; Paroxetine; Pregnancy; Pregnancy Complicatio | 2017 |
Use of selective serotonin reuptake inhibitors during pregnancy and risk of major and cardiovascular malformations: an update.
Topics: Abnormalities, Drug-Induced; Cardiovascular Abnormalities; Citalopram; Depression; Female; Fluoxetin | 2010 |
3 trials available for citalopram and Complications, Pregnancy
| Article | Year |
|---|---|
The relationship between antidepressant use and smoking cessation in pregnant women in treatment for substance abuse.
Topics: Adult; Antidepressive Agents, Second-Generation; Bupropion; Citalopram; Depressive Disorder, Major; | 2010 |
Citalopram in pregnancy and lactation.
Topics: Adult; Analysis of Variance; Antidepressive Agents, Second-Generation; Child Development; Citalopram | 2002 |
Changes in antidepressant metabolism and dosing across pregnancy and early postpartum.
Topics: Adult; Antidepressive Agents, Second-Generation; Citalopram; Depression, Postpartum; Depressive Diso | 2008 |
Changes in antidepressant metabolism and dosing across pregnancy and early postpartum.
Topics: Adult; Antidepressive Agents, Second-Generation; Citalopram; Depression, Postpartum; Depressive Diso | 2008 |
Changes in antidepressant metabolism and dosing across pregnancy and early postpartum.
Topics: Adult; Antidepressive Agents, Second-Generation; Citalopram; Depression, Postpartum; Depressive Diso | 2008 |
Changes in antidepressant metabolism and dosing across pregnancy and early postpartum.
Topics: Adult; Antidepressive Agents, Second-Generation; Citalopram; Depression, Postpartum; Depressive Diso | 2008 |
17 other studies available for citalopram and Complications, Pregnancy
| Article | Year |
|---|---|
Pregnancy exposure to citalopram - Therapeutic drug monitoring in maternal blood, amniotic fluid and cord blood.
Topics: Adult; Amniotic Fluid; Citalopram; Cordocentesis; Dose-Response Relationship, Drug; Drug Monitoring; | 2017 |
Neonatal abstinence syndrome due to prenatally citalopram exposure: A case report.
Topics: Anticonvulsants; Antidepressive Agents, Second-Generation; Citalopram; Depressive Disorder, Major; F | 2017 |
Neonatal morbidity due to maternal use of two antidepressant drugs.
Topics: Anti-Anxiety Agents; Antidepressive Agents; Benzodiazepines; Citalopram; Drug Therapy, Combination; | 2018 |
Neonatal toxicity following maternal citalopram treatment.
Topics: Citalopram; Depressive Disorder, Major; Diagnosis, Differential; Female; Half-Life; Humans; Infant, | 2013 |
Warning of risk to foetus for mothers using SSRIs.
Topics: Abnormalities, Drug-Induced; Citalopram; Depressive Disorder; Female; Humans; Pregnancy; Pregnancy C | 2013 |
Use of escitalopram during pregnancy: navigating towards international guidelines and the real world.
Topics: Adult; Citalopram; Female; Fetus; Humans; Infant, Newborn; International Cooperation; Lactation; Liv | 2008 |
Acute voluntary intoxication with selective serotonin reuptake inhibitors during the third trimester of pregnancy: therapeutic management of mother and fetus.
Topics: Adrenal Cortex Hormones; Adult; Antidotes; Calcium Channel Blockers; Charcoal; Citalopram; Depressio | 2008 |
Ziprasidone and citalopram use in pregnancy and lactation in a woman with psychotic depression.
Topics: Adult; Affective Disorders, Psychotic; Antipsychotic Agents; Citalopram; Drug Therapy, Combination; | 2009 |
Antidepressant use during pregnancy. FPIN’s clinical inquiries.
Topics: Adult; Antidepressive Agents, Second-Generation; Antidepressive Agents, Tricyclic; Citalopram; Cyclo | 2011 |
Antidepressant induced cholestasis: hepatocellular redistribution of multidrug resistant protein (MRP2).
Topics: Acute Disease; Adult; Antidepressive Agents; Antidepressive Agents, Second-Generation; Antidepressiv | 2003 |
Placental passage of antidepressant medications.
Topics: Adult; Antidepressive Agents; Citalopram; Depressive Disorder; Dose-Response Relationship, Drug; Fem | 2003 |
Neonatal complications after intrauterine exposure to SSRI antidepressants.
Topics: Antidepressive Agents; Citalopram; Depression; Female; Fluoxetine; Fluvoxamine; Follow-Up Studies; F | 2004 |
Serotonin reuptake inhibitors attenuate morphine withdrawal syndrome in neonatal rats passively exposed to morphine.
Topics: Animals; Animals, Newborn; Behavior, Animal; Citalopram; Clomipramine; Female; Fluoxetine; Maternal- | 2005 |
Citalopram use in pregnancy: prospective comparative evaluation of pregnancy and fetal outcome.
Topics: Antidepressive Agents, Second-Generation; Birth Weight; Citalopram; Female; Gestational Age; Humans; | 2005 |
Necrotizing enterocolitis associated with in utero and breast milk exposure to the selective serotonin reuptake inhibitor, escitalopram.
Topics: Citalopram; Enterocolitis, Necrotizing; Female; Humans; Infant, Newborn; Milk, Human; Pregnancy; Pre | 2007 |
Consecutive exposure to lamotrigine and citalopram during pregnancy.
Topics: Antidepressive Agents, Second-Generation; Anxiety; Citalopram; Depression; Drug Administration Sched | 2007 |
Unrecognized pregnancy during citalopram treatment.
Topics: Abortion, Induced; Adult; Citalopram; Depressive Disorder; Female; Fetus; Humans; Maternal-Fetal Exc | 1993 |