citalopram has been researched along with Complication, Postoperative in 7 studies
Citalopram: A furancarbonitrile that is one of the serotonin uptake inhibitors used as an antidepressant. The drug is also effective in reducing ethanol uptake in alcoholics and is used in depressed patients who also suffer from TARDIVE DYSKINESIA in preference to tricyclic antidepressants, which aggravate dyskinesia.
citalopram : A racemate comprising equimolar amounts of (R)-citalopram and its enantiomer, escitalopram. It is used as an antidepressant, although only escitalopram is active.
1-[3-(dimethylamino)propyl]-1-(4-fluorophenyl)-1,3-dihydro-2-benzofuran-5-carbonitrile : A nitrile that is 1,3-dihydro-2-benzofuran-5-carbonitrile in which one of the hydrogens at position 1 is replaced by a p-fluorophenyl group, while the other is replaced by a 3-(dimethylamino)propyl group.
| Excerpt | Relevance | Reference |
|---|---|---|
| " We report the development of severe hyponatremia leading to adverse clinical effects due to escitalopram and thiazide diuretic use concomitantly in a patient with depression after emergency coronary artery bypass grafting." | 7.83 | Hyponatremia Due to Escitalopram and Thiazide Use After Cardiac Surgery. ( Aksoy, E; Çağlı, K; Diken, Aİ; Doğan, İ; Erçen Diken, Ö; Yalçınkaya, A; Yılmaz, S, 2016) |
| " We report the development of severe hyponatremia leading to adverse clinical effects due to escitalopram and thiazide diuretic use concomitantly in a patient with depression after emergency coronary artery bypass grafting." | 3.83 | Hyponatremia Due to Escitalopram and Thiazide Use After Cardiac Surgery. ( Aksoy, E; Çağlı, K; Diken, Aİ; Doğan, İ; Erçen Diken, Ö; Yalçınkaya, A; Yılmaz, S, 2016) |
| "Moreover, the treatment of depression and anxiety can be associated with a reduced mortality." | 2.66 | Mood disorders and outcomes in lung cancer patients undergoing surgery: a brief summery. ( Aguglia, E; Migliore, M; Signorelli, MS; Surace, T, 2020) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (28.57) | 29.6817 |
| 2010's | 4 (57.14) | 24.3611 |
| 2020's | 1 (14.29) | 2.80 |
| Authors | Studies |
|---|---|
| Signorelli, MS | 1 |
| Surace, T | 1 |
| Migliore, M | 1 |
| Aguglia, E | 1 |
| Schumacher, LD | 1 |
| Blumer, V | 1 |
| Chaparro, SV | 1 |
| Ugurlu, TT | 1 |
| Acar, G | 1 |
| Karadag, F | 1 |
| Acar, F | 1 |
| Diken, Aİ | 1 |
| Yalçınkaya, A | 1 |
| Erçen Diken, Ö | 1 |
| Aksoy, E | 1 |
| Doğan, İ | 1 |
| Yılmaz, S | 1 |
| Çağlı, K | 1 |
| Khavandi, A | 1 |
| Whitaker, J | 1 |
| Gonna, H | 1 |
| Schulberg, HC | 1 |
| Belnap, BH | 1 |
| Houck, PR | 1 |
| Mazumdar, S | 1 |
| Reynolds, CF | 1 |
| Rollman, BL | 1 |
| Holland, S | 1 |
| Townley, S | 1 |
| Summerfield, R | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Treatment of Depression Following Bypass Surgery[NCT00091962] | 453 participants (Actual) | Interventional | 2003-08-31 | Completed | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
The 12-item Duke Activity Status Index (DASI). Scores range from 0-58.2, and higher scores the better the functional capacity (Am J Cardiol. 1989;64(10):651-654). (NCT00091962)
Timeframe: 8 months post CABG
| Intervention | units on a scale (Mean) |
|---|---|
| Depressed Intervention | 25.2 |
| Depressed Usual Care | 21.4 |
| Non-Depressed Control | 33.2 |
"The 36-item Medical Outcomes Study Form (v.2) Mental Component Scale (SF-36 MCS). Range 0-100; Population norm is 50 with standard deviation of 10. Higher scores are better.~Ware J, Kosinski M, Keller S. SF-36 Physical and Mental Health Summary Scales: A User's Manual. 2nd ed. Boston, MA: New England Medical Center; 1994." (NCT00091962)
Timeframe: Measured 8 months post-CABG
| Intervention | units on a scale (Mean) |
|---|---|
| Depressed Intervention | 50.0 |
| Depressed Usual Care | 46.2 |
| Non-Depressed Control | 57.2 |
"The 36-item Medical Outcomes Study Form (v.2) Physical Component Scale (SF-36 PCS). Range 0-100; Population norm is 50 with standard deviation of 10. Higher scores are better.~Ware J, Kosinski M, Keller S. SF-36 Physical and Mental Health Summary Scales: A User's Manual. 2nd ed. Boston, MA: New England Medical Center; 1994." (NCT00091962)
Timeframe: 8 months post CABG
| Intervention | participants (Mean) |
|---|---|
| Depressed Intervention | 44.0 |
| Depressed Usual Care | 41.4 |
| Non-Depressed Control | 48.7 |
The 17-item Depression Interview and Structured Hamilton (DISH) version of the Hamilton Rating Scale for Depression Standard provides an accurate DSM-IV diagnosis of a cardiac patient's mood disorder and a reliable HRS-D score. Range 0-52. Higher scores are worse. Psychosom Med. 2002;64(6):897-905 (NCT00091962)
Timeframe: 8 months post CABG
| Intervention | units on a scale (Mean) |
|---|---|
| Depressed Intervention | 9.0 |
| Depressed Usual Care | 11.4 |
| Non-Depressed Control Group | 3.8 |
2 reviews available for citalopram and Complication, Postoperative
| Article | Year |
|---|---|
Mood disorders and outcomes in lung cancer patients undergoing surgery: a brief summery.
Topics: Anxiety; Citalopram; Cognitive Behavioral Therapy; Combined Modality Therapy; Depression; Humans; Lu | 2020 |
Methylene blue-induced serotonin syndrome after left ventricular assist device implantation: A case report and literature review.
Topics: Citalopram; Drug Synergism; Heart-Assist Devices; Humans; Male; Methylene Blue; Middle Aged; Postope | 2017 |
1 trial available for citalopram and Complication, Postoperative
| Article | Year |
|---|---|
Treating post-CABG depression with telephone-delivered collaborative care: does patient age affect treatment and outcome?
Topics: Age Factors; Aged; Citalopram; Coronary Artery Bypass; Depression; Female; Health Services for the A | 2011 |
4 other studies available for citalopram and Complication, Postoperative
| Article | Year |
|---|---|
Manic episode following deep brain stimulation of the subthalamic nucleus for Parkinson's disease: a case report.
Topics: Antiparkinson Agents; Anxiety; Bipolar Disorder; Citalopram; Deep Brain Stimulation; Electrodes, Imp | 2014 |
Hyponatremia Due to Escitalopram and Thiazide Use After Cardiac Surgery.
Topics: Antidepressive Agents; Citalopram; Coronary Artery Bypass; Depression; Drug Therapy, Combination; Em | 2016 |
Serotonin toxicity precipitated by concomitant use of citalopram and methylene blue.
Topics: Adult; Citalopram; Coloring Agents; Drug Interactions; Female; Humans; Methylene Blue; Parathyroidec | 2008 |
Citalopram--a risk factor for postoperative hyponatraemia.
Topics: Aged; Antidepressive Agents, Second-Generation; Citalopram; Female; Humans; Hyponatremia; Postoperat | 2003 |