Page last updated: 2024-10-25

citalopram and Breast Neoplasms

citalopram has been researched along with Breast Neoplasms in 13 studies

Citalopram: A furancarbonitrile that is one of the serotonin uptake inhibitors used as an antidepressant. The drug is also effective in reducing ethanol uptake in alcoholics and is used in depressed patients who also suffer from TARDIVE DYSKINESIA in preference to tricyclic antidepressants, which aggravate dyskinesia.
citalopram : A racemate comprising equimolar amounts of (R)-citalopram and its enantiomer, escitalopram. It is used as an antidepressant, although only escitalopram is active.
1-[3-(dimethylamino)propyl]-1-(4-fluorophenyl)-1,3-dihydro-2-benzofuran-5-carbonitrile : A nitrile that is 1,3-dihydro-2-benzofuran-5-carbonitrile in which one of the hydrogens at position 1 is replaced by a p-fluorophenyl group, while the other is replaced by a 3-(dimethylamino)propyl group.

Breast Neoplasms: Tumors or cancer of the human BREAST.

Research Excerpts

ExcerptRelevanceReference
"We aimed to evaluate and compare the efficacy of venlafaxine and citalopram on hot flashes in breast cancer women receiving tamoxifen."9.69Evaluation and Comparison of Citalopram and Venlafaxine for Management of Hot Flashes in Women with Breast Cancer. ( Esfandbod, M; Etesam, F; Taleghani, SY, 2023)
" Because the efficacy of escitalopram, a potent serotonin reuptake inhibitor, has not been well evaluated in cancer patients, we investigated its effects on depression and quality of life in outpatients with breast cancer."9.16Rapid improvement of depression and quality of life with escitalopram treatment in outpatients with breast cancer: a 12-week, open-label prospective trial. ( Bae, JN; Hahm, BJ; Kim, JH; Lee, BJ; Park, HY, 2012)
"Breast cancer patients with indications for an SSRI may be prescribed citalopram - and possibly other SSRI - without adversely affecting the outcome of adjuvant therapy with tamoxifen."7.76Breast cancer recurrence risk related to concurrent use of SSRI antidepressants and tamoxifen. ( Ahern, TP; Cronin-Fenton, D; Ewertz, M; Garne, JP; Hamilton-Dutoit, S; Lash, TL; Lunetta, KL; Pedersen, L; Rosenberg, CL; Silliman, RA; Sørensen, HT, 2010)
"Tamoxifen remains an important adjuvant therapy to reduce the rate of breast cancer recurrence among patients with oestrogen-receptor-positive tumours."7.74Tamoxifen's protection against breast cancer recurrence is not reduced by concurrent use of the SSRI citalopram. ( Ahern, TP; Cronin-Fenton, D; Ewertz, M; Garne, JP; Hamilton-Dutoit, S; Lash, TL; Lunetta, KL; Pedersen, L; Rosenberg, CL; Silliman, RA; Sørensen, HT, 2008)
"We aimed to evaluate and compare the efficacy of venlafaxine and citalopram on hot flashes in breast cancer women receiving tamoxifen."5.69Evaluation and Comparison of Citalopram and Venlafaxine for Management of Hot Flashes in Women with Breast Cancer. ( Esfandbod, M; Etesam, F; Taleghani, SY, 2023)
" Therefore we investigated whether there is a drug-drug interaction between tamoxifen and SRIs resulting in a prolonged QTc-interval."5.51The Risk of QTc-Interval Prolongation in Breast Cancer Patients Treated with Tamoxifen in Combination with Serotonin Reuptake Inhibitors. ( Berger, FA; Binkhorst, L; de Groot, NMS; Hussaarts, KGAM; Mathijssen, RHJ; Mathijssen-van Stein, D; Oomen-de Hoop, E; van Alphen, RJ; van Gelder, T; van Leeuwen, RWF, 2019)
" Because the efficacy of escitalopram, a potent serotonin reuptake inhibitor, has not been well evaluated in cancer patients, we investigated its effects on depression and quality of life in outpatients with breast cancer."5.16Rapid improvement of depression and quality of life with escitalopram treatment in outpatients with breast cancer: a 12-week, open-label prospective trial. ( Bae, JN; Hahm, BJ; Kim, JH; Lee, BJ; Park, HY, 2012)
"Breast cancer patients with indications for an SSRI may be prescribed citalopram - and possibly other SSRI - without adversely affecting the outcome of adjuvant therapy with tamoxifen."3.76Breast cancer recurrence risk related to concurrent use of SSRI antidepressants and tamoxifen. ( Ahern, TP; Cronin-Fenton, D; Ewertz, M; Garne, JP; Hamilton-Dutoit, S; Lash, TL; Lunetta, KL; Pedersen, L; Rosenberg, CL; Silliman, RA; Sørensen, HT, 2010)
"Tamoxifen remains an important adjuvant therapy to reduce the rate of breast cancer recurrence among patients with oestrogen-receptor-positive tumours."3.74Tamoxifen's protection against breast cancer recurrence is not reduced by concurrent use of the SSRI citalopram. ( Ahern, TP; Cronin-Fenton, D; Ewertz, M; Garne, JP; Hamilton-Dutoit, S; Lash, TL; Lunetta, KL; Pedersen, L; Rosenberg, CL; Silliman, RA; Sørensen, HT, 2008)
" Therefore we investigated whether there is a drug-drug interaction between tamoxifen and SRIs resulting in a prolonged QTc-interval."1.51The Risk of QTc-Interval Prolongation in Breast Cancer Patients Treated with Tamoxifen in Combination with Serotonin Reuptake Inhibitors. ( Berger, FA; Binkhorst, L; de Groot, NMS; Hussaarts, KGAM; Mathijssen, RHJ; Mathijssen-van Stein, D; Oomen-de Hoop, E; van Alphen, RJ; van Gelder, T; van Leeuwen, RWF, 2019)
"As a result, SSRIinduced akathisia is very frequently under-recognized."1.40A case of akathisia induced by escitalopram: case report & review of literature. ( Basu, B; De, S; Dutta, N; Gangopadhyay, T; Mandal, B; Mondal, S, 2014)

Research

Studies (13)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's2 (15.38)29.6817
2010's10 (76.92)24.3611
2020's1 (7.69)2.80

Authors

AuthorsStudies
Taleghani, SY1
Etesam, F1
Esfandbod, M1
Hussaarts, KGAM1
Berger, FA1
Binkhorst, L1
Oomen-de Hoop, E1
van Leeuwen, RWF1
van Alphen, RJ1
Mathijssen-van Stein, D1
de Groot, NMS1
Mathijssen, RHJ1
van Gelder, T1
Basu, B1
Gangopadhyay, T1
Dutta, N1
Mandal, B1
De, S1
Mondal, S1
Biglia, N1
Bounous, VE1
Susini, T1
Pecchio, S1
Sgro, LG1
Tuninetti, V1
Torta, R1
Lash, TL3
Pedersen, L2
Cronin-Fenton, D3
Ahern, TP2
Rosenberg, CL2
Lunetta, KL2
Silliman, RA2
Hamilton-Dutoit, S2
Garne, JP2
Ewertz, M2
Sørensen, HT3
Shchepotin, IB1
Zotov, AS1
Dobzhenko, MN1
Appiani, F1
Carroll, BT1
Muñoz, C1
Trecco, J1
Park, HY1
Lee, BJ1
Kim, JH1
Bae, JN1
Hahm, BJ1
Buyko, E1
Beisswanger, E1
Hahn, U1
Rodríguez, J1
Castañeda, G1
Muñoz, L1
Granet, R1
Sutter, S1

Reviews

1 review available for citalopram and Breast Neoplasms

ArticleYear
[Selective serotonin reuptake inhibitors and mammary pathologies].
    Voprosy onkologii, 2010, Volume: 56, Issue:4

    Topics: Antidepressive Agents; Breast Neoplasms; Citalopram; Clinical Trials as Topic; Female; Fluoxetine; F

2010

Trials

3 trials available for citalopram and Breast Neoplasms

ArticleYear
Evaluation and Comparison of Citalopram and Venlafaxine for Management of Hot Flashes in Women with Breast Cancer.
    Drug research, 2023, Volume: 73, Issue:8

    Topics: Adult; Aged; Breast Neoplasms; Citalopram; Double-Blind Method; Female; Hot Flashes; Humans; Menopau

2023
Duloxetine and escitalopram for hot flushes: efficacy and compliance in breast cancer survivors.
    European journal of cancer care, 2018, Volume: 27, Issue:1

    Topics: Administration, Oral; Adult; Aged; Analysis of Variance; Antidepressive Agents; Antidepressive Agent

2018
Rapid improvement of depression and quality of life with escitalopram treatment in outpatients with breast cancer: a 12-week, open-label prospective trial.
    Progress in neuro-psychopharmacology & biological psychiatry, 2012, Mar-30, Volume: 36, Issue:2

    Topics: Adolescent; Adult; Aged; Antidepressive Agents; Breast Neoplasms; Citalopram; Depressive Disorder, M

2012

Other Studies

9 other studies available for citalopram and Breast Neoplasms

ArticleYear
The Risk of QTc-Interval Prolongation in Breast Cancer Patients Treated with Tamoxifen in Combination with Serotonin Reuptake Inhibitors.
    Pharmaceutical research, 2019, Dec-16, Volume: 37, Issue:1

    Topics: Aged; Antidepressive Agents, Second-Generation; Antineoplastic Agents, Hormonal; Breast Neoplasms; C

2019
A case of akathisia induced by escitalopram: case report & review of literature.
    Current drug safety, 2014, Volume: 9, Issue:1

    Topics: Adrenergic beta-Antagonists; Antidepressive Agents, Second-Generation; Breast Neoplasms; Citalopram;

2014
Tamoxifen's protection against breast cancer recurrence is not reduced by concurrent use of the SSRI citalopram.
    British journal of cancer, 2008, Aug-19, Volume: 99, Issue:4

    Topics: Adult; Aged; Antineoplastic Agents, Hormonal; Breast Neoplasms; Case-Control Studies; Citalopram; Dr

2008
Breast cancer recurrence risk related to concurrent use of SSRI antidepressants and tamoxifen.
    Acta oncologica (Stockholm, Sweden), 2010, Volume: 49, Issue:3

    Topics: Adult; Aged; Antidepressive Agents, Second-Generation; Antineoplastic Agents, Hormonal; Breast Neopl

2010
Selective serotonin reuptake inhibitors and adjuvant tamoxifen therapy: risk of breast cancer recurrence and mortality.
    Future oncology (London, England), 2010, Volume: 6, Issue:6

    Topics: Alleles; Antineoplastic Agents, Hormonal; Biotransformation; Breast Neoplasms; Citalopram; Cytochrom

2010
Tamoxifen-SSRIs interaction: clinical manifestations of inhibition and lack of inhibition of CYP2D6.
    Annals of clinical psychiatry : official journal of the American Academy of Clinical Psychiatrists, 2011, Volume: 23, Issue:2

    Topics: Antineoplastic Agents, Phytogenic; Breast Neoplasms; Carcinoma, Ductal; Citalopram; Cytochrome P-450

2011
The extraction of pharmacogenetic and pharmacogenomic relations--a case study using PharmGKB.
    Pacific Symposium on Biocomputing. Pacific Symposium on Biocomputing, 2012

    Topics: Aryl Hydrocarbon Hydroxylases; Breast Neoplasms; Citalopram; Computational Biology; Cytochrome P-450

2012
Rapid determination of letrozole, citalopram and their metabolites by high performance liquid chromatography-fluorescence detection in urine: Method validation and application to real samples.
    Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 2013, Jan-15, Volume: 913-914

    Topics: Antidepressive Agents, Second-Generation; Antineoplastic Agents; Breast Neoplasms; Chromatography, H

2013
Can chemotherapy induce reactions of recollection?
    Psycho-oncology, 2007, Volume: 16, Issue:11

    Topics: Antidepressive Agents; Antineoplastic Agents; Breast Neoplasms; Citalopram; Depressive Disorder; Fem

2007