Page last updated: 2024-10-25

citalopram and Body Weight

citalopram has been researched along with Body Weight in 49 studies

Citalopram: A furancarbonitrile that is one of the serotonin uptake inhibitors used as an antidepressant. The drug is also effective in reducing ethanol uptake in alcoholics and is used in depressed patients who also suffer from TARDIVE DYSKINESIA in preference to tricyclic antidepressants, which aggravate dyskinesia.
citalopram : A racemate comprising equimolar amounts of (R)-citalopram and its enantiomer, escitalopram. It is used as an antidepressant, although only escitalopram is active.
1-[3-(dimethylamino)propyl]-1-(4-fluorophenyl)-1,3-dihydro-2-benzofuran-5-carbonitrile : A nitrile that is 1,3-dihydro-2-benzofuran-5-carbonitrile in which one of the hydrogens at position 1 is replaced by a p-fluorophenyl group, while the other is replaced by a 3-(dimethylamino)propyl group.

Body Weight: The mass or quantity of heaviness of an individual. It is expressed by units of pounds or kilograms.

Research Excerpts

ExcerptRelevanceReference
"Thirthy-two female patients who had been diagnosed as having anorexia nervosa restricting subtype according to the DSM IV (Diagnostic and Statistical Manual of Mental Disorders-IV), were enrolled in a 6-month open trial with citalopram at a starting dose of 20 mg."9.08Citalopram in anorexia nervosa. ( Pallanti, S; Quercioli, L; Ramacciotti, A, 1997)
"Although we could not establish an association between the anxiety level of rats with either the onset or severity of LID, our results showed that citalopram was able to mediate a partial alleviation in LID after chronic treatment, and the extent of recovery was negatively correlated to the anxiety measures of individual animals."7.74The role of anxiety in the development of levodopa-induced dyskinesias in an animal model of Parkinson's disease, and the effect of chronic treatment with the selective serotonin reuptake inhibitor citalopram. ( Barker, RA; Kuan, WL; Zhao, JW, 2008)
"The selective sigma2 (sigma2) ligand Lu 28-179, or 1'-[4[1-(4-fluorophenyl)-1H-indol-3-yl]-l-butyl]spiro[isobenzofuran++ +-1(3H),4'-piperidine], was studied in the chronic mild stress (CMS) model of depression."7.70The selective sigma2 ligand Lu 28-179 has an antidepressant-like profile in the rat chronic mild stress model of depression. ( Papp, M; Sánchez, C, 2000)
"Atherosclerosis is one of the most common disorders among the elderly."5.40Comparison of the effects of escitalopram and atorvastatin on diet-induced atherosclerosis in rats. ( Abdelbary, A; Hamza, M; Unis, A, 2014)
" To compare changes in body weight during treatment with different antidepressants, body weight and height were measured at baseline and after 6, 8, 12 and 26 wk treatment with escitalopram or nortriptyline in 630 adults with moderate-to-severe unipolar depression participating in GENDEP, a part-randomized open-label study."5.15Changes in body weight during pharmacological treatment of depression. ( Aitchison, KJ; Dernovsek, MZ; Farmer, A; Gray, JM; Hauser, J; Henigsberg, N; Kalember, P; Keers, R; Kozel, D; Larsen, ER; Maier, W; McGuffin, P; Mendlewicz, J; Mors, O; Placentino, A; Rietschel, M; Souery, D; Strohmaier, J; Szczepankiewicz, A; Uher, R; Zobel, A, 2011)
"Higher BMI and obesity predicted poor response to nortriptyline but did not significantly influence response to escitalopram."5.14Body weight as a predictor of antidepressant efficacy in the GENDEP project. ( Aitchison, KJ; Dernovsek, MZ; Farmer, A; Gunasinghe, C; Hauser, J; Henigsberg, N; Kalember, P; Kozel, D; Larsen, ER; Leszczynska-Rodziewicz, A; Linotte, S; Maier, W; McGuffin, P; Mors, O; Pedrini, L; Perroud, N; Placentino, A; Rietschel, M; Souery, D; Strohmaier, J; Uher, R; Zobel, A, 2009)
"Thirthy-two female patients who had been diagnosed as having anorexia nervosa restricting subtype according to the DSM IV (Diagnostic and Statistical Manual of Mental Disorders-IV), were enrolled in a 6-month open trial with citalopram at a starting dose of 20 mg."5.08Citalopram in anorexia nervosa. ( Pallanti, S; Quercioli, L; Ramacciotti, A, 1997)
"In this retrospective cohort study from participants in the Mayo Clinic RIGHT study who were prescribed citalopram, paroxetine, sertraline, or fluoxetine, our aim was to evaluate the association of metabolizer phenotype and total body weight after 6 months of SSRIs initiation."4.12Association between CYP metabolizer phenotypes and selective serotonin reuptake inhibitors induced weight gain: a retrospective cohort study. ( Acosta, A; Bielinski, SJ; Camilleri, M; Cifuentes, L; Decker, PA; Gonzalez-Izundegui, D; Hurtado, MD; Moyer, AM; Ricardo-Silgado, ML; Singh, S, 2022)
" Using imipramine and citalopram, we sought to assess which drug would be more appropriate as pharmacological reference in paradigms of depression in C57BL6N mice by measuring their effect on liquid consumption, home cage activity, body weight and long-term memory in naïve animals treated with each compound at generally used dose of 15 mg/kg/day."3.79The differential effects of chronic imipramine or citalopram administration on physiological and behavioral outcomes in naïve mice. ( Anokhin, K; Anthony, DC; Dolgov, O; Kubatiev, A; Schroeter, C; Steinbusch, HM; Strekalova, T, 2013)
" We examined whether treatment with a selective serotonin reuptake inhibitor [escitalopram (ESC)] could downregulate HPA axis activity and restore insulin sensitivity in LBW rats."3.76Treatment with an SSRI antidepressant restores hippocampo-hypothalamic corticosteroid feedback and reverses insulin resistance in low-birth-weight rats. ( Buhl, CS; Buhl, ES; Elfving, B; Jensen, TK; Jessen, N; Kristiansen, SB; Lund, S; Petersen, KF; Pold, R; Schmitz, O; Solskov, L; Wegener, G, 2010)
"Although we could not establish an association between the anxiety level of rats with either the onset or severity of LID, our results showed that citalopram was able to mediate a partial alleviation in LID after chronic treatment, and the extent of recovery was negatively correlated to the anxiety measures of individual animals."3.74The role of anxiety in the development of levodopa-induced dyskinesias in an animal model of Parkinson's disease, and the effect of chronic treatment with the selective serotonin reuptake inhibitor citalopram. ( Barker, RA; Kuan, WL; Zhao, JW, 2008)
"A stress-induced decrease in sucrose preference in rodents is regarded as an analog of anhedonia, a key symptom of depression."3.73Selective effects of citalopram in a mouse model of stress-induced anhedonia with a control for chronic stress. ( Bartsch, D; Dolgov, O; Gorenkova, N; Schunk, E; Strekalova, T, 2006)
"Triiodothyronine (T3) has been shown to accelerate and potentiate the clinical response to tricyclic antidepressant (TCA) treatment in depressive disorders."3.71Chronic effects of triiodothyronine in combination with imipramine on 5-HT transporter, 5-HT(1A) and 5-HT(2A) receptors in adult rat brain. ( Jeanningros, R; Mazzola-Pomietto, P; Moreau, X, 2001)
"Corticosterone administration, which markedly reduced body weight gains and adrenal weights in both strains, increased Km and Vmax values in SHRs but decreased these values in WKY rats, compared to vehicle (2."3.71Effects of corticosterone ingestion on hippocampal [(3)H]serotonin reuptake in inbred rat strains. ( Chaouloff, F; Coomans, V; Fernandez, F; Mormede, P, 2001)
"The selective sigma2 (sigma2) ligand Lu 28-179, or 1'-[4[1-(4-fluorophenyl)-1H-indol-3-yl]-l-butyl]spiro[isobenzofuran++ +-1(3H),4'-piperidine], was studied in the chronic mild stress (CMS) model of depression."3.70The selective sigma2 ligand Lu 28-179 has an antidepressant-like profile in the rat chronic mild stress model of depression. ( Papp, M; Sánchez, C, 2000)
"Bupropion is presumed to be a dopamine-norepinephrine reuptake inhibitor and is an effective antidepressant."2.44Bupropion: a review of its use in the management of major depressive disorder. ( Curran, MP; Dhillon, S; Yang, LP, 2008)
"Escitalopram treatment significantly decreased PAI-1 levels in the serum, but not in the CSF."1.43Plasminogen Activator Inhibitor-1 in depression: Results from Animal and Clinical Studies. ( Chen, S; Jiang, H; Li, X; Liang, J; Lu, N; Yuan, Y; Yue, Y; Zhang, Z, 2016)
"Atherosclerosis is one of the most common disorders among the elderly."1.40Comparison of the effects of escitalopram and atorvastatin on diet-induced atherosclerosis in rats. ( Abdelbary, A; Hamza, M; Unis, A, 2014)
"Escitalopram treatment decreased anxiety-related behaviours in stressed animals, by increasing the time spent in the central part of the arena with respect to saline treated stressed animals, without affecting exploratory related behaviours."1.40Behavioural and transcriptional effects of escitalopram in the chronic escape deficit model of depression. ( Alboni, S; Benatti, C; Blom, JM; Brunello, N; Gandolfi, F; Mendlewicz, J; Tascedda, F, 2014)
"The citalopram-treated male mice showed altered sexual behavior, specifically a significant reduction in the number of intromissions preceding ejaculation compared with the vehicle-treated mice."1.38Early-life citalopram-induced impairments in sexual behavior and the role of androgen receptor. ( Parhar, IS; Putteeraj, M; Soga, T; Song, KP; Wong, DW, 2012)
"Escitalopram (ES-CIT) is a widely used, highly specific antidepressant."1.35Effects of escitalopram on the regulation of brain-derived neurotrophic factor and nerve growth factor protein levels in a rat model of chronic stress. ( Abumaria, N; Danker-Hopfe, H; Fuchs, E; Hellweg, R; Hiemke, C; Schulte-Herbrüggen, O; Ziegler, A, 2009)
"Citalopram pretreatment blocked MDMA-related reductions in aggressive and exploratory behavior measured in the social interaction and hole-board tests respectively."1.35Dissociation of the neurochemical and behavioral toxicology of MDMA ('Ecstasy') by citalopram. ( Ali, SF; Fraiman, JB; Meyer, JS; Owens, CB; Piper, BJ, 2008)
"This 6-week, open-label, multicenter study evaluated the efficacy and safety of quetiapine in combination with citalopram in adult patients (n=25) with ICD-10/DSM-IV unipolar psychotic depression."1.34Quetiapine in combination with citalopram in patients with unipolar psychotic depression. ( Aschauer, H; Hrubos, W; Kasper, S; Konstantinidis, A; Lehofer, M; Nirnberger, G; Windhager, E, 2007)
"Citalopram was retested 18 weeks after the first treatment during 1 week, with continuous access to ethanol; 10 mg/kg had no effect and 40 mg/kg decreased ethanol intake at day 1, reaching a minimum in day 3."1.30Citalopram as an inhibitor of voluntary ethanol intake in the male rat. ( Hedlund, L; Wahlström, G, 1998)

Research

Studies (49)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's7 (14.29)18.2507
2000's19 (38.78)29.6817
2010's20 (40.82)24.3611
2020's3 (6.12)2.80

Authors

AuthorsStudies
Ricardo-Silgado, ML1
Singh, S1
Cifuentes, L1
Decker, PA1
Gonzalez-Izundegui, D1
Moyer, AM1
Hurtado, MD1
Camilleri, M1
Bielinski, SJ1
Acosta, A1
Puzhko, S1
Aboushawareb, SAE1
Kudrina, I1
Schuster, T1
Barnett, TA1
Renoux, C1
Bartlett, G1
Henn, L1
Zanta, NC1
Girardi, CEN1
Suchecki, D1
Hale, MW1
Lukkes, JL1
Dady, KF1
Kelly, KJ1
Paul, ED1
Smith, DG1
Raison, CL1
Lowry, CA1
Pinheiro, IL1
da Silva, AI1
Reginato, A1
da Silva Filho, RC1
Galindo, LCM1
Matos, RJB1
de Souza Ferraz, JC1
Toscano Meneses da Silva Castro, AE1
Milanski Ferreira, M1
Manhães de Castro, R2
de Souza, SL1
Strekalova, T2
Anthony, DC1
Dolgov, O2
Anokhin, K1
Kubatiev, A1
Steinbusch, HM1
Schroeter, C1
Gupta, D1
Kurhe, Y2
Radhakrishnan, M1
Unis, A1
Abdelbary, A1
Hamza, M1
Benatti, C1
Alboni, S1
Blom, JM1
Gandolfi, F1
Mendlewicz, J2
Brunello, N1
Tascedda, F1
Lin, DH1
Zhang, XR1
Ye, DQ1
Xi, GJ1
Hui, JJ1
Liu, SS1
Li, LJ1
Zhang, ZJ2
Li, XL1
Yuan, YG1
Xu, H1
Wu, D1
Gong, WG1
Geng, LY1
Wu, FF1
Tang, H1
Xu, L1
Mahesh, R1
Liang, S1
Wang, T1
Hu, X1
Luo, J1
Li, W1
Wu, X1
Duan, Y1
Jin, F1
Jiang, H1
Li, X1
Chen, S1
Lu, N1
Yue, Y1
Liang, J1
Zhang, Z1
Yuan, Y1
Sprowles, JL1
Hufgard, JR1
Gutierrez, A1
Bailey, RA1
Jablonski, SA1
Williams, MT2
Vorhees, CV2
Bjørnebekk, A1
Mathé, AA2
Gruber, SH1
Brené, S1
Uher, R2
Mors, O2
Hauser, J2
Rietschel, M2
Maier, W2
Kozel, D2
Henigsberg, N2
Souery, D2
Placentino, A2
Perroud, N1
Dernovsek, MZ2
Strohmaier, J2
Larsen, ER2
Zobel, A2
Leszczynska-Rodziewicz, A1
Kalember, P2
Pedrini, L1
Linotte, S1
Gunasinghe, C1
Aitchison, KJ2
McGuffin, P2
Farmer, A2
Schulte-Herbrüggen, O1
Fuchs, E1
Abumaria, N1
Ziegler, A1
Danker-Hopfe, H1
Hiemke, C1
Hellweg, R1
Jin, Y1
Pollock, BG1
Frank, E1
Cassano, GB1
Rucci, P1
Müller, DJ1
Kennedy, JL1
Forgione, RN1
Kirshner, M1
Kepple, G1
Fagiolini, A1
Kupfer, DJ1
Bies, RR1
Buhl, ES1
Jensen, TK1
Jessen, N1
Elfving, B1
Buhl, CS1
Kristiansen, SB1
Pold, R1
Solskov, L1
Schmitz, O1
Wegener, G1
Lund, S1
Petersen, KF1
Keers, R1
Gray, JM1
Szczepankiewicz, A1
Mikrouli, E1
Wörtwein, G1
Soylu, R1
Petersén, Å1
Młyniec, K1
Nowak, G1
Soga, T1
Wong, DW1
Putteeraj, M1
Song, KP1
Parhar, IS1
Flandreau, EI1
Bourke, CH1
Ressler, KJ1
Vale, WW1
Nemeroff, CB1
Owens, MJ1
Schaefer, TL1
Grace, CE1
Braun, AA1
Amos-Kroohs, RM1
Graham, DL1
Skelton, MR1
Fassino, S1
Leombruni, P1
Daga, G1
Brustolin, A1
Migliaretti, G1
Cavallo, F1
Rovera, G1
Kugelberg, FC2
Apelqvist, G2
Bengtsson, F2
Pallanti, S1
Quercioli, L1
Ramacciotti, A1
Allard, P1
Gram, L1
Timdahl, K1
Behnke, K1
Hanson, M1
Søgaard, J1
Maciag, D1
Simpson, KL1
Coppinger, D1
Lu, Y1
Wang, Y1
Lin, RC1
Paul, IA1
Gorenkova, N1
Schunk, E1
Bartsch, D1
Konstantinidis, A1
Hrubos, W1
Nirnberger, G1
Windhager, E1
Lehofer, M1
Aschauer, H1
Kasper, S1
Piper, BJ1
Fraiman, JB1
Owens, CB1
Ali, SF1
Meyer, JS1
Kuan, WL1
Zhao, JW1
Barker, RA1
Dhillon, S1
Yang, LP1
Curran, MP1
Cabrera, TM1
Levy, AD1
Li, Q1
van de Kar, LD1
Battaglia, G1
Bouwer, CD1
Harvey, BH1
Izumi, J1
Washizuka, M1
Hayashi-Kuwabara, Y1
Yoshinaga, K1
Tanaka, Y1
Ikeda, Y1
Kiuchi, Y1
Oguchi, K1
Kulikov, A1
Mormède, P2
Chaouloff, F2
Hedlund, L1
Wahlström, G1
Keeney, AJ1
Hogg, S1
Sánchez, C1
Papp, M1
Barreto Medeiros, JM1
Mendes da Silva, C1
Ferreira, LM1
Guedes, RC2
Cabral Filho, JE1
Costa, JA2
Carlsson, B1
Ahlner, J1
Moreau, X1
Jeanningros, R1
Mazzola-Pomietto, P1
Medeiros, JM1
Silva, CM1
Sougey, EB1
Castro, CM1
Castro, RM1
Fernandez, F1
Coomans, V1
Amâncio-Dos-Santos, A1
Manhães-De-Castro, R1
Costa-Cruz, RR1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Examining Immune-Based Mechanisms of Action for Mild-Intensity Whole Body Hyperthermia (WBH) in the Treatment of Major Depressive Disorder[NCT03787290]Phase 235 participants (Anticipated)Interventional2023-12-01Not yet recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

2 reviews available for citalopram and Body Weight

ArticleYear
Excess body weight as a predictor of response to treatment with antidepressants in patients with depressive disorder.
    Journal of affective disorders, 2020, 04-15, Volume: 267

    Topics: Adult; Antidepressive Agents; Body Weight; Citalopram; Depressive Disorder; Humans; Nortriptyline

2020
Bupropion: a review of its use in the management of major depressive disorder.
    Drugs, 2008, Volume: 68, Issue:5

    Topics: Antidepressive Agents, Second-Generation; Body Weight; Bupropion; Citalopram; Delayed-Action Prepara

2008

Trials

7 trials available for citalopram and Body Weight

ArticleYear
Body weight as a predictor of antidepressant efficacy in the GENDEP project.
    Journal of affective disorders, 2009, Volume: 118, Issue:1-3

    Topics: Adult; Affect; Antidepressive Agents, Second-Generation; Antidepressive Agents, Tricyclic; Appetite;

2009
Effect of age, weight, and CYP2C19 genotype on escitalopram exposure.
    Journal of clinical pharmacology, 2010, Volume: 50, Issue:1

    Topics: Adult; Age Factors; Aged; Alleles; Antidepressive Agents, Second-Generation; Aryl Hydrocarbon Hydrox

2010
Changes in body weight during pharmacological treatment of depression.
    The international journal of neuropsychopharmacology, 2011, Volume: 14, Issue:3

    Topics: Adult; Aged; Antidepressive Agents, Tricyclic; Body Mass Index; Body Weight; Citalopram; Depressive

2011
Efficacy of citalopram in anorexia nervosa: a pilot study.
    European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology, 2002, Volume: 12, Issue:5

    Topics: Adolescent; Adult; Ambulatory Care; Anorexia Nervosa; Body Mass Index; Body Weight; Citalopram; Fema

2002
Citalopram in anorexia nervosa.
    Eating and weight disorders : EWD, 1997, Volume: 2, Issue:4

    Topics: Adolescent; Adult; Anorexia Nervosa; Body Mass Index; Body Weight; Citalopram; Female; Humans; Selec

1997
Efficacy and tolerability of venlafaxine in geriatric outpatients with major depression: a double-blind, randomised 6-month comparative trial with citalopram.
    International journal of geriatric psychiatry, 2004, Volume: 19, Issue:12

    Topics: Aged; Aged, 80 and over; Antidepressive Agents; Antidepressive Agents, Second-Generation; Body Weigh

2004
Phasic craving for carbohydrate observed with citalopram.
    International clinical psychopharmacology, 1996, Volume: 11, Issue:4

    Topics: Adolescent; Adult; Body Weight; Citalopram; Depressive Disorder; Dietary Carbohydrates; Female; Huma

1996

Other Studies

40 other studies available for citalopram and Body Weight

ArticleYear
Association between CYP metabolizer phenotypes and selective serotonin reuptake inhibitors induced weight gain: a retrospective cohort study.
    BMC medicine, 2022, 07-26, Volume: 20, Issue:1

    Topics: Body Weight; Citalopram; Cytochrome P-450 CYP2C19; Cytochrome P-450 CYP2C9; Cytochrome P-450 CYP2D6;

2022
Chronic Escitalopram Treatment Does Not Alter the Effects of Neonatal Stress on Hippocampal BDNF Levels, 5-HT
    Molecular neurobiology, 2021, Volume: 58, Issue:3

    Topics: Aging; Animals; Animals, Newborn; Behavior, Animal; Body Weight; Brain-Derived Neurotrophic Factor;

2021
Whole-body hyperthermia and a subthreshold dose of citalopram act synergistically to induce antidepressant-like behavioral responses in adolescent rats.
    Progress in neuro-psychopharmacology & biological psychiatry, 2017, 10-03, Volume: 79, Issue:Pt B

    Topics: Analysis of Variance; Animals; Antidepressive Agents; Body Temperature; Body Weight; Citalopram; Dep

2017
Neonatal fluoxetine exposure modulates serotonergic neurotransmission and disturb inhibitory action of serotonin on food intake.
    Behavioural brain research, 2019, 01-14, Volume: 357-358

    Topics: Age Factors; Animals; Animals, Newborn; Body Weight; Citalopram; Eating; Female; Fluoxetine; Food De

2019
The differential effects of chronic imipramine or citalopram administration on physiological and behavioral outcomes in naïve mice.
    Behavioural brain research, 2013, May-15, Volume: 245

    Topics: Analysis of Variance; Animals; Antidepressive Agents, Tricyclic; Behavior, Animal; Body Weight; Cita

2013
Antidepressant effects of insulin in streptozotocin induced diabetic mice: Modulation of brain serotonin system.
    Physiology & behavior, 2014, Apr-22, Volume: 129

    Topics: Animals; Antidepressive Agents; Antidepressive Agents, Second-Generation; Blood Glucose; Body Weight

2014
Comparison of the effects of escitalopram and atorvastatin on diet-induced atherosclerosis in rats.
    Canadian journal of physiology and pharmacology, 2014, Volume: 92, Issue:3

    Topics: Animals; Aorta, Abdominal; Atherosclerosis; Atorvastatin; Body Weight; Citalopram; Diet, High-Fat; H

2014
Behavioural and transcriptional effects of escitalopram in the chronic escape deficit model of depression.
    Behavioural brain research, 2014, Oct-01, Volume: 272

    Topics: Animals; Antidepressive Agents, Second-Generation; Anxiety; Body Weight; Chronic Disease; Citalopram

2014
The Role of the Two-Pore Domain Potassium Channel TREK-1 in the Therapeutic Effects of Escitalopram in a Rat Model of Poststroke Depression.
    CNS neuroscience & therapeutics, 2015, Volume: 21, Issue:6

    Topics: Animals; Body Weight; Brain; Cell Proliferation; Citalopram; Depression; Disease Models, Animal; Exp

2015
Changed Synaptic Plasticity in Neural Circuits of Depressive-Like and Escitalopram-Treated Rats.
    The international journal of neuropsychopharmacology, 2015, Apr-21, Volume: 18, Issue:10

    Topics: Animals; Antidepressive Agents; Blotting, Western; Body Weight; Brain; Chronic Disease; Citalopram;

2015
Ondansetron attenuates co-morbid depression and anxiety associated with obesity by inhibiting the biochemical alterations and improving serotonergic neurotransmission.
    Pharmacology, biochemistry, and behavior, 2015, Volume: 136

    Topics: Animals; Anxiety; Behavior, Animal; Body Weight; Brain; Citalopram; Corticosterone; Depression; Diet

2015
Administration of Lactobacillus helveticus NS8 improves behavioral, cognitive, and biochemical aberrations caused by chronic restraint stress.
    Neuroscience, 2015, Dec-03, Volume: 310

    Topics: Adrenocorticotropic Hormone; Animals; Anxiety; Behavior, Animal; Body Weight; Brain-Derived Neurotro

2015
Plasminogen Activator Inhibitor-1 in depression: Results from Animal and Clinical Studies.
    Scientific reports, 2016, 07-26, Volume: 6

    Topics: Animals; Behavior, Animal; Body Weight; Case-Control Studies; Chronic Disease; Citalopram; Depressio

2016
Perinatal exposure to the selective serotonin reuptake inhibitor citalopram alters spatial learning and memory, anxiety, depression, and startle in Sprague-Dawley rats.
    International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience, 2016, Volume: 54

    Topics: Age Factors; Amphetamines; Animals; Animals, Newborn; Anxiety; Body Weight; Citalopram; Depression;

2016
Housing conditions modulate escitalopram effects on antidepressive-like behaviour and brain neurochemistry.
    The international journal of neuropsychopharmacology, 2008, Volume: 11, Issue:8

    Topics: Animals; Antidepressive Agents, Second-Generation; Behavior, Animal; Body Weight; Brain Chemistry; C

2008
Effects of escitalopram on the regulation of brain-derived neurotrophic factor and nerve growth factor protein levels in a rat model of chronic stress.
    Journal of neuroscience research, 2009, Aug-15, Volume: 87, Issue:11

    Topics: Adrenal Glands; Animals; Antidepressive Agents, Second-Generation; Body Weight; Brain; Brain-Derived

2009
Treatment with an SSRI antidepressant restores hippocampo-hypothalamic corticosteroid feedback and reverses insulin resistance in low-birth-weight rats.
    American journal of physiology. Endocrinology and metabolism, 2010, Volume: 298, Issue:5

    Topics: Adrenocorticotropic Hormone; Analysis of Variance; Animals; Area Under Curve; Blood Glucose; Body We

2010
Increased numbers of orexin/hypocretin neurons in a genetic rat depression model.
    Neuropeptides, 2011, Volume: 45, Issue:6

    Topics: Animals; Antidepressive Agents, Second-Generation; Behavior, Animal; Body Weight; Citalopram; Depres

2011
Zinc deficiency induces behavioral alterations in the tail suspension test in mice. Effect of antidepressants.
    Pharmacological reports : PR, 2012, Volume: 64, Issue:2

    Topics: Animals; Antidepressive Agents; Behavior, Animal; Body Weight; Citalopram; Depression; Drug Resistan

2012
Early-life citalopram-induced impairments in sexual behavior and the role of androgen receptor.
    Neuroscience, 2012, Dec-06, Volume: 225

    Topics: Animals; Animals, Newborn; Antidepressive Agents, Second-Generation; Body Weight; Citalopram; Disord

2012
Escitalopram alters gene expression and HPA axis reactivity in rats following chronic overexpression of corticotropin-releasing factor from the central amygdala.
    Psychoneuroendocrinology, 2013, Volume: 38, Issue:8

    Topics: Amygdala; Animals; Anxiety; Behavior, Animal; Body Weight; Citalopram; Corticotropin-Releasing Hormo

2013
Cognitive impairments from developmental exposure to serotonergic drugs: citalopram and MDMA.
    The international journal of neuropsychopharmacology, 2013, Volume: 16, Issue:6

    Topics: Animals; Animals, Newborn; Body Weight; Citalopram; Cognition Disorders; Disease Models, Animal; Fem

2013
Effects of chronic citalopram treatment on central and peripheral spontaneous open-field behaviours in rats.
    Pharmacology & toxicology, 2002, Volume: 90, Issue:6

    Topics: Animals; Antidepressive Agents, Second-Generation; Behavior, Animal; Body Weight; Brain; Circadian R

2002
Neonatal antidepressant exposure has lasting effects on behavior and serotonin circuitry.
    Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 2006, Volume: 31, Issue:1

    Topics: Animals; Animals, Newborn; Antidepressive Agents; Antidepressive Agents, Tricyclic; Antigens, Nuclea

2006
Selective effects of citalopram in a mouse model of stress-induced anhedonia with a control for chronic stress.
    Behavioural pharmacology, 2006, Volume: 17, Issue:3

    Topics: Animals; Body Weight; Chronic Disease; Citalopram; Depression; Drinking; Hindlimb Suspension; Immers

2006
Quetiapine in combination with citalopram in patients with unipolar psychotic depression.
    Progress in neuro-psychopharmacology & biological psychiatry, 2007, Jan-30, Volume: 31, Issue:1

    Topics: Adolescent; Adult; Affective Disorders, Psychotic; Aged; Antidepressive Agents; Antipsychotic Agents

2007
Dissociation of the neurochemical and behavioral toxicology of MDMA ('Ecstasy') by citalopram.
    Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 2008, Volume: 33, Issue:5

    Topics: Analysis of Variance; Animals; Behavior, Animal; Body Temperature; Body Weight; Brain Chemistry; Cit

2008
The role of anxiety in the development of levodopa-induced dyskinesias in an animal model of Parkinson's disease, and the effect of chronic treatment with the selective serotonin reuptake inhibitor citalopram.
    Psychopharmacology, 2008, Volume: 197, Issue:2

    Topics: Adrenal Cortex Hormones; Amphetamine; Animals; Anxiety; Blotting, Western; Body Weight; Central Nerv

2008
Prenatal methamphetamine attenuates serotonin mediated renin secretion in male and female rat progeny: evidence for selective long-term dysfunction of serotonin pathways in brain.
    Synapse (New York, N.Y.), 1993, Volume: 15, Issue:3

    Topics: Analysis of Variance; Animals; Body Weight; Brain; Cerebral Cortex; Citalopram; Female; Hypothalamus

1993
Protective effect of citalopram against the attenuation of the alpha 1-potentiation of cAMP formation in Fischer 344 strain rats.
    Behavioural brain research, 1997, Volume: 83, Issue:1-2

    Topics: Adrenergic Uptake Inhibitors; Animals; Behavior, Animal; Body Weight; Brain Chemistry; Citalopram; C

1997
Effects of adrenalectomy and corticosterone replacement on diurnal [3H]citalopram binding in rat midbrain.
    Neuroscience letters, 1997, Jan-31, Volume: 222, Issue:2

    Topics: Adrenalectomy; Adrenocorticotropic Hormone; Animals; Anti-Inflammatory Agents; Body Weight; Carrier

1997
Citalopram as an inhibitor of voluntary ethanol intake in the male rat.
    Alcohol (Fayetteville, N.Y.), 1998, Volume: 16, Issue:4

    Topics: Alcoholism; Animals; Body Weight; Citalopram; Drinking; Drug Tolerance; Ethanol; Male; Rats; Rats, S

1998
Behavioural consequences of repeated social defeat in the mouse: preliminary evaluation of a potential animal model of depression.
    Behavioural pharmacology, 1999, Volume: 10, Issue:8

    Topics: Aggression; Alcohol Drinking; Animals; Antidepressive Agents, Second-Generation; Behavior, Animal; B

1999
The selective sigma2 ligand Lu 28-179 has an antidepressant-like profile in the rat chronic mild stress model of depression.
    Behavioural pharmacology, 2000, Volume: 11, Issue:2

    Topics: Animals; Anti-Anxiety Agents; Antidepressive Agents, Second-Generation; Antidepressive Agents, Tricy

2000
Reduction of intraspecific aggression in adult rats by neonatal treatment with a selective serotonin reuptake inhibitor.
    Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas, 2001, Volume: 34, Issue:1

    Topics: Aggression; Animals; Animals, Newborn; Body Weight; Citalopram; Male; Random Allocation; Rats; Rats,

2001
In vivo steady-state pharmacokinetic outcome following clinical and toxic doses of racemic citalopram to rats.
    British journal of pharmacology, 2001, Volume: 132, Issue:8

    Topics: Animals; Behavior, Animal; Biotransformation; Body Weight; Brain; Citalopram; Drug Implants; Male; R

2001
Chronic effects of triiodothyronine in combination with imipramine on 5-HT transporter, 5-HT(1A) and 5-HT(2A) receptors in adult rat brain.
    Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 2001, Volume: 24, Issue:6

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Antidepressive Agents, Tricyclic; Body Weight; Brai

2001
Action of selective serotonin reuptake inhibitor on aggressive behavior in adult rat submitted to the neonatal malnutrition.
    Arquivos de neuro-psiquiatria, 2001, Volume: 59, Issue:3-A

    Topics: Aggression; Animals; Animals, Suckling; Behavior, Animal; Body Weight; Brain; Citalopram; Diet; Fema

2001
Effects of corticosterone ingestion on hippocampal [(3)H]serotonin reuptake in inbred rat strains.
    Endocrine regulations, 2001, Volume: 35, Issue:3

    Topics: Adrenal Glands; Animals; Body Weight; Carrier Proteins; Citalopram; Corticosterone; Hippocampus; Mal

2001
Citalopram has an antagonistic action on cortical spreading depression in well-nourished and early-malnourished adult rats.
    Nutritional neuroscience, 2002, Volume: 5, Issue:2

    Topics: Animals; Body Weight; Citalopram; Cortical Spreading Depression; Injections, Intraperitoneal; Male;

2002