Page last updated: 2024-10-25

citalopram and Agoraphobia

citalopram has been researched along with Agoraphobia in 10 studies

Citalopram: A furancarbonitrile that is one of the serotonin uptake inhibitors used as an antidepressant. The drug is also effective in reducing ethanol uptake in alcoholics and is used in depressed patients who also suffer from TARDIVE DYSKINESIA in preference to tricyclic antidepressants, which aggravate dyskinesia.
citalopram : A racemate comprising equimolar amounts of (R)-citalopram and its enantiomer, escitalopram. It is used as an antidepressant, although only escitalopram is active.
1-[3-(dimethylamino)propyl]-1-(4-fluorophenyl)-1,3-dihydro-2-benzofuran-5-carbonitrile : A nitrile that is 1,3-dihydro-2-benzofuran-5-carbonitrile in which one of the hydrogens at position 1 is replaced by a p-fluorophenyl group, while the other is replaced by a 3-(dimethylamino)propyl group.

Agoraphobia: Obsessive, persistent, intense fear of open places.

Research Excerpts

ExcerptRelevanceReference
"The effect of a short treatment (7 days) with citalopram on the reactivity to inhalations of 35% CO2 and 65% oxygen and on clinical symptomatology was investigated in 15 patients with panic disorder who had a positive response to 35% CO2 inhalation."9.09The 35% CO2 hyperreactivity and clinical symptomatology in patients with panic disorder after 1 week of treatment with citalopram: an open study. ( Bellodi, L; Bertani, A; Bussi, R; Caldirola, D; Perna, G, 2001)
"The current trial is a second-step stratified randomized design comparing two treatment conditions-selective serotonin reuptake inhibitor (SSRI; paroxetine or citalopram; n = 34) and continued CBT (n = 24)-in a sample of individuals classified as treatment nonresponders to an initial course of CBT for panic disorder."5.22SECOND-STAGE TREATMENTS FOR RELATIVE NONRESPONDERS TO COGNITIVE BEHAVIORAL THERAPY (CBT) FOR PANIC DISORDER WITH OR WITHOUT AGORAPHOBIA-CONTINUED CBT VERSUS SSRI: A RANDOMIZED CONTROLLED TRIAL. ( Barlow, DH; Farchione, TJ; Gallagher, MW; Gorman, JM; Payne, LA; Shear, MK; White, KS; Woods, SW, 2016)
"We aimed to examine whether anxiety sensitivity and agoraphobic fear could affect the time taken to remission after 24 weeks of open-label escitalopram treatment of patients with panic disorder (PD)."5.16Psychological characteristics of early remitters in patients with panic disorder. ( Chung, SK; Kang, EH; Kim, EJ; Kim, JH; Kim, YR; Ku, JI; Lee, JH; Lee, SH; Lee, SY; Park, HJ; Woo, JM; Yu, BH, 2012)
" The patients were assessed on measures of interpretative bias (homophone task), anxiety and depression before being prescribed an SSRI (paroxetine or citalopram)."5.11Effect of short-term SSRI treatment on cognitive bias in generalised anxiety disorder. ( Baldwin, DS; Bradley, BP; Brodrick, P; Mogg, K, 2004)
"The effect of a short treatment (7 days) with citalopram on the reactivity to inhalations of 35% CO2 and 65% oxygen and on clinical symptomatology was investigated in 15 patients with panic disorder who had a positive response to 35% CO2 inhalation."5.09The 35% CO2 hyperreactivity and clinical symptomatology in patients with panic disorder after 1 week of treatment with citalopram: an open study. ( Bellodi, L; Bertani, A; Bussi, R; Caldirola, D; Perna, G, 2001)
"Treatment with citalopram resulted in a gradual decline of anxiety symptoms."1.32Alexithymia in Noonan syndrome. ( Egger, JI; Hendrikx, JL; MDoorakkers, MC; Tuinier, S; Van der Burgt, I; Verhoeven, WM, 2004)

Research

Studies (10)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (10.00)18.2507
2000's6 (60.00)29.6817
2010's3 (30.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Payne, LA1
White, KS1
Gallagher, MW1
Woods, SW1
Shear, MK1
Gorman, JM1
Farchione, TJ1
Barlow, DH1
Benvenuti, A1
Rucci, P1
Calugi, S1
Cassano, GB1
Miniati, M1
Frank, E1
Park, HJ1
Kim, EJ1
Ku, JI1
Woo, JM1
Lee, SH1
Chung, SK1
Lee, SY1
Kim, YR1
Kang, EH1
Lee, JH1
Kim, JH1
Yu, BH1
Perna, G2
Alpini, D1
Caldirola, D2
Raponi, G1
Cesarani, A1
Bellodi, L2
Verhoeven, WM1
Hendrikx, JL1
MDoorakkers, MC1
Egger, JI1
Van der Burgt, I1
Tuinier, S1
Mogg, K1
Baldwin, DS1
Brodrick, P1
Bradley, BP1
Marchesi, C1
Cantoni, A1
Fontò, S1
Giannelli, MR1
Maggini, C1
Warwick, JM1
Carey, P1
Van der Linden, G1
Prinsloo, C1
Niehaus, D1
Seedat, S1
Dupont, P1
Stein, DJ1
Bertani, A1
Bussi, R1
Humble, M1
Wistedt, B1

Clinical Trials (2)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Treatment of Panic Disorder: Long Term Strategies[NCT00000368]Phase 3379 participants (Actual)Interventional1999-02-28Completed
The Role of Orexin in Human Panic Disorder[NCT02593682]Phase 43 participants (Actual)Interventional2016-05-31Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

1 review available for citalopram and Agoraphobia

ArticleYear
Serotonin, panic disorder and agoraphobia: short-term and long-term efficacy of citalopram in panic disorders.
    International clinical psychopharmacology, 1992, Volume: 6 Suppl 5

    Topics: Adult; Agoraphobia; Citalopram; Dose-Response Relationship, Drug; Drug Administration Schedule; Fema

1992

Trials

6 trials available for citalopram and Agoraphobia

ArticleYear
SECOND-STAGE TREATMENTS FOR RELATIVE NONRESPONDERS TO COGNITIVE BEHAVIORAL THERAPY (CBT) FOR PANIC DISORDER WITH OR WITHOUT AGORAPHOBIA-CONTINUED CBT VERSUS SSRI: A RANDOMIZED CONTROLLED TRIAL.
    Depression and anxiety, 2016, Volume: 33, Issue:5

    Topics: Adult; Agoraphobia; Citalopram; Cognitive Behavioral Therapy; Combined Modality Therapy; Female; Hum

2016
Relationship of residual mood and panic-agoraphobic spectrum phenomenology to quality of life and functional impairment in patients with major depression.
    International clinical psychopharmacology, 2010, Volume: 25, Issue:2

    Topics: Adult; Affect; Agoraphobia; Antidepressive Agents, Second-Generation; Citalopram; Depressive Disorde

2010
Psychological characteristics of early remitters in patients with panic disorder.
    Psychiatry research, 2012, May-30, Volume: 197, Issue:3

    Topics: Adult; Agoraphobia; Anxiety; Citalopram; Female; Humans; Male; Panic Disorder; Psychiatric Status Ra

2012
Serotonergic modulation of the balance system in panic disorder: an open study.
    Depression and anxiety, 2003, Volume: 17, Issue:2

    Topics: Adult; Agoraphobia; Citalopram; Dose-Response Relationship, Drug; Drug Administration Schedule; Fema

2003
Effect of short-term SSRI treatment on cognitive bias in generalised anxiety disorder.
    Psychopharmacology, 2004, Volume: 176, Issue:3-4

    Topics: Adult; Affect; Agoraphobia; Citalopram; Cognition; Cross-Sectional Studies; Depression; Female; Huma

2004
The 35% CO2 hyperreactivity and clinical symptomatology in patients with panic disorder after 1 week of treatment with citalopram: an open study.
    Journal of clinical psychopharmacology, 2001, Volume: 21, Issue:3

    Topics: Adolescent; Adult; Agoraphobia; Antidepressive Agents, Second-Generation; Carbon Dioxide; Citalopram

2001

Other Studies

3 other studies available for citalopram and Agoraphobia

ArticleYear
Alexithymia in Noonan syndrome.
    Genetic counseling (Geneva, Switzerland), 2004, Volume: 15, Issue:1

    Topics: Abnormalities, Multiple; Adult; Affective Symptoms; Agoraphobia; Chromosomes, Human, Pair 12; Citalo

2004
Predictors of symptom resolution in panic disorder after one year of pharmacological treatment: a naturalistic study.
    Pharmacopsychiatry, 2006, Volume: 39, Issue:2

    Topics: Adult; Agoraphobia; Anxiety Disorders; Citalopram; Diagnostic and Statistical Manual of Mental Disor

2006
A comparison of the effects of citalopram and moclobemide on resting brain perfusion in social anxiety disorder.
    Metabolic brain disease, 2006, Volume: 21, Issue:2-3

    Topics: Adult; Agoraphobia; Antidepressive Agents; Brain; Cerebrovascular Circulation; Citalopram; Female; H

2006