Page last updated: 2024-10-25

citalopram and Acute Coronary Syndrome

citalopram has been researched along with Acute Coronary Syndrome in 28 studies

Citalopram: A furancarbonitrile that is one of the serotonin uptake inhibitors used as an antidepressant. The drug is also effective in reducing ethanol uptake in alcoholics and is used in depressed patients who also suffer from TARDIVE DYSKINESIA in preference to tricyclic antidepressants, which aggravate dyskinesia.
citalopram : A racemate comprising equimolar amounts of (R)-citalopram and its enantiomer, escitalopram. It is used as an antidepressant, although only escitalopram is active.
1-[3-(dimethylamino)propyl]-1-(4-fluorophenyl)-1,3-dihydro-2-benzofuran-5-carbonitrile : A nitrile that is 1,3-dihydro-2-benzofuran-5-carbonitrile in which one of the hydrogens at position 1 is replaced by a p-fluorophenyl group, while the other is replaced by a 3-(dimethylamino)propyl group.

Acute Coronary Syndrome: An episode of MYOCARDIAL ISCHEMIA that generally lasts longer than a transient anginal episode that ultimately may lead to MYOCARDIAL INFARCTION.

Research Excerpts

ExcerptRelevanceReference
"To investigate the effect on long-term major adverse cardiac events (MACE) of escitalopram treatment of depression in patients with recent ACS."9.27Effect of Escitalopram vs Placebo Treatment for Depression on Long-term Cardiac Outcomes in Patients With Acute Coronary Syndrome: A Randomized Clinical Trial. ( Ahn, Y; Bae, KY; Hong, YJ; Jeong, MH; Kang, HJ; Kim, JH; Kim, JM; Kim, JW; Kim, MC; Kim, SW; Lee, HJ; Lee, YS; Shin, IS; Stewart, R; Yoon, JS, 2018)
" Successful treatment of depression and anxiety with escitalopram had significant beneficial effects on suicidal ideation in these patients."9.22Determinants and escitalopram treatment effects on suicidal ideation in patients with acute coronary syndrome: Findings from the K-DEPACS and EsDEPACS studies. ( Ahn, Y; Bae, KY; Hong, YJ; Jeong, MH; Kang, H; Kang, HJ; Kim, JM; Kim, SW; Shin, IS; Yoon, JS, 2016)
"We investigated roles of plasma homocysteine and MTHFR gene in relation to risks and treatment responses of depression in ACS."9.22Predictive value of homocysteine for depression after acute coronary syndrome. ( Ahn, Y; Bae, KY; Hong, YJ; Jeong, MH; Kang, H; Kang, HJ; Kim, JM; Kim, SW; Moon, WJ; Shin, IS; Stewart, R; Yoon, JS, 2016)
"These results indicate that escitalopram has clinically meaningful antidepressant effects with no evidence of reduced cardiovascular safety in depressive disorder following ACS."9.20Escitalopram treatment for depressive disorder following acute coronary syndrome: a 24-week double-blind, placebo-controlled trial. ( Ahn, Y; Bae, KY; Hong, YJ; Jeong, MH; Jung, BO; Kang, G; Kang, HJ; Kim, JH; Kim, JK; Kim, JM; Kim, SW; Shin, HY; Shin, IS; Stewart, R; Yoon, JS, 2015)
" Of 446 baseline participants with co-morbid depressive disorders, 300 were randomized to a 24-week double blind trial of escitalopram or placebo, while the remaining 146 received medical treatment only (MTO)."9.20Effects of depression co-morbidity and treatment on quality of life in patients with acute coronary syndrome: the Korean depression in ACS (K-DEPACS) and the escitalopram for depression in ACS (EsDEPACS) study. ( Ahn, Y; Bae, KY; Hong, YJ; Jeong, MH; Kang, HJ; Kim, JM; Kim, SW; Shin, IS; Stewart, R; Yoon, JS, 2015)
"A cross-sectional study in patients with ACS within 2 w post-ACS, and a 24-w double-blind controlled trial of escitalopram against placebo for patients with ACS who have comorbid depressive disorders."9.20Correlates and Escitalopram Treatment Effects on Sleep Disturbance in Patients with Acute Coronary Syndrome: K-DEPACS and EsDEPACS. ( Ahn, Y; Bae, KY; Hong, YJ; Jeong, MH; Kang, HJ; Kim, JM; Kim, SW; Shin, IS; Stewart, R; Yoon, JS, 2015)
"Of 120 patients treated with escitalopram 2 developed depression versus 10 in placebo treated group (log rank, p=0."9.16Effects of escitalopram in prevention of depression in patients with acute coronary syndrome (DECARD). ( Andersen, NL; Birket-Smith, M; Hanash, JA; Hansen, BH; Hansen, JF; Nielsen, OW; Rasmussen, A, 2012)
"The DECARD (DEpression in patients with Coronary ARtery Disease) trial assessed the prophylactic effect of escitalopram on depression after ACS."9.16Cardiovascular safety of one-year escitalopram therapy in clinically nondepressed patients with acute coronary syndrome: results from the DEpression in patients with Coronary ARtery Disease (DECARD) trial. ( Birket-Smith, M; Hanash, JA; Hansen, BH; Hansen, JF; Nielsen, OW; Rasmussen, A, 2012)
"Two hundred forty non-depressed patients with acute coronary syndrome are randomized to treatment with either escitalopram or placebo for 1 year."9.14Rationale, design and methodology of a double-blind, randomized, placebo-controlled study of escitalopram in prevention of Depression in Acute Coronary Syndrome (DECARD). ( Birket-Smith, M; Hanash, JA; Hansen, BH; Hansen, JF; Rasmussen, A, 2009)
"This study aimed to investigate whether social support deficit has moderating effects on depressive and cardiac outcomes in an antidepressant trial for depressed patients with acute coronary syndrome as a secondary analysis using Escitalopram for DEPression in acute coronary syndrome study (ClinicalTrial."5.30Social support deficit and depression treatment outcomes in patients with acute coronary syndrome: Findings from the EsDEPACS study. ( Ahn, Y; Bae, KY; Hong, YJ; Jeong, MH; Kang, HJ; Kim, JM; Kim, JW; Kim, SW; Shin, IS; Yoon, JS, 2019)
"To investigate the effect on long-term major adverse cardiac events (MACE) of escitalopram treatment of depression in patients with recent ACS."5.27Effect of Escitalopram vs Placebo Treatment for Depression on Long-term Cardiac Outcomes in Patients With Acute Coronary Syndrome: A Randomized Clinical Trial. ( Ahn, Y; Bae, KY; Hong, YJ; Jeong, MH; Kang, HJ; Kim, JH; Kim, JM; Kim, JW; Kim, MC; Kim, SW; Lee, HJ; Lee, YS; Shin, IS; Stewart, R; Yoon, JS, 2018)
" Of the 294 patients with depression, 207 participated in a 24-week double blind trial of escitalopram or placebo."5.22Influences of the Big Five personality traits on the treatment response and longitudinal course of depression in patients with acute coronary syndrome: A randomised controlled trial. ( Ahn, Y; Bae, KY; Hong, YJ; Jeong, MH; Kim, JM; Kim, SW; Kim, SY; Shin, IS; Stewart, R; Yoon, JS, 2016)
" Successful treatment of depression and anxiety with escitalopram had significant beneficial effects on suicidal ideation in these patients."5.22Determinants and escitalopram treatment effects on suicidal ideation in patients with acute coronary syndrome: Findings from the K-DEPACS and EsDEPACS studies. ( Ahn, Y; Bae, KY; Hong, YJ; Jeong, MH; Kang, H; Kang, HJ; Kim, JM; Kim, SW; Shin, IS; Yoon, JS, 2016)
"We investigated roles of plasma homocysteine and MTHFR gene in relation to risks and treatment responses of depression in ACS."5.22Predictive value of homocysteine for depression after acute coronary syndrome. ( Ahn, Y; Bae, KY; Hong, YJ; Jeong, MH; Kang, H; Kang, HJ; Kim, JM; Kim, SW; Moon, WJ; Shin, IS; Stewart, R; Yoon, JS, 2016)
"Escitalopram may prevent depression following acute coronary syndrome."5.20Prevention of depression in patients with acute coronary syndrome (DECARD) randomized trial: effects on and by self-reported health. ( Birket-Smith, M; Hanash, JA; Hansen, BH; Hjorthøj, CR; Rasmussen, A, 2015)
"These results indicate that escitalopram has clinically meaningful antidepressant effects with no evidence of reduced cardiovascular safety in depressive disorder following ACS."5.20Escitalopram treatment for depressive disorder following acute coronary syndrome: a 24-week double-blind, placebo-controlled trial. ( Ahn, Y; Bae, KY; Hong, YJ; Jeong, MH; Jung, BO; Kang, G; Kang, HJ; Kim, JH; Kim, JK; Kim, JM; Kim, SW; Shin, HY; Shin, IS; Stewart, R; Yoon, JS, 2015)
" Of 446 baseline participants with co-morbid depressive disorders, 300 were randomized to a 24-week double blind trial of escitalopram or placebo, while the remaining 146 received medical treatment only (MTO)."5.20Effects of depression co-morbidity and treatment on quality of life in patients with acute coronary syndrome: the Korean depression in ACS (K-DEPACS) and the escitalopram for depression in ACS (EsDEPACS) study. ( Ahn, Y; Bae, KY; Hong, YJ; Jeong, MH; Kang, HJ; Kim, JM; Kim, SW; Shin, IS; Stewart, R; Yoon, JS, 2015)
"A cross-sectional study in patients with ACS within 2 w post-ACS, and a 24-w double-blind controlled trial of escitalopram against placebo for patients with ACS who have comorbid depressive disorders."5.20Correlates and Escitalopram Treatment Effects on Sleep Disturbance in Patients with Acute Coronary Syndrome: K-DEPACS and EsDEPACS. ( Ahn, Y; Bae, KY; Hong, YJ; Jeong, MH; Kang, HJ; Kim, JM; Kim, SW; Shin, IS; Stewart, R; Yoon, JS, 2015)
"The DECARD (DEpression in patients with Coronary ARtery Disease) trial assessed the prophylactic effect of escitalopram on depression after ACS."5.16Cardiovascular safety of one-year escitalopram therapy in clinically nondepressed patients with acute coronary syndrome: results from the DEpression in patients with Coronary ARtery Disease (DECARD) trial. ( Birket-Smith, M; Hanash, JA; Hansen, BH; Hansen, JF; Nielsen, OW; Rasmussen, A, 2012)
"We used pooled datasets from 1-year follow-up data from a 24-week randomized double-blind placebo-controlled trial (RCT) of escitalopram for treatment of depressive disorder and data from a naturalistic, prospective, observational cohort study in patients with ACS."4.98Interactions between pro-inflammatory cytokines and statins on depression in patients with acute coronary syndrome. ( Ahn, YK; Bae, KY; Berk, M; Hong, YJ; Jeong, MH; Kang, HJ; Kim, JM; Kim, SW; Shin, IS; Yoon, JS, 2018)
"Depressive disorder was diagnosed according to DSM-IV criteria and included prevalent depressive disorder at baseline and incident or persistent depressive disorder at follow-up based on depression status at the two examinations."2.90Methylation of the glucocorticoid receptor gene associated with depression in patients with acute coronary syndrome. ( Ahn, Y; Bae, KY; Hong, YJ; Jeong, MH; Kang, HJ; Kim, HR; Kim, JM; Kim, SW; Shin, IS; Shin, MG; Yoon, JS, 2019)
"Appropriate detection and treatment of depressive disorder are clearly important in ACS patients."2.80Predictors of depressive disorder following acute coronary syndrome: Results from K-DEPACS and EsDEPACS. ( Ahn, Y; Bae, KY; Hong, YJ; Jeong, MH; Kang, HJ; Kim, JM; Kim, SW; Shin, IS; Stewart, R; Yoon, JS, 2015)
"Escitalopram treatment was associated with beneficial effects compared to placebo and MTO on one-year outcomes on HAMD, MADRS and SOFAS (p-values<0."2.80Effects of depression screening on psychiatric outcomes in patients with acute coronary syndrome: Findings from the K-DEPACS and EsDEPACS studies. ( Ahn, Y; Bae, KY; Hong, YJ; Jeong, MH; Kang, HJ; Kim, JM; Kim, SW; Shin, IS; Stewart, R; Yoon, JS, 2015)
"Escitalopram was more effective than placebo for treating depressive disorder in those with a higher methylation, and this effects lead to prevent persistent depressive disorder."2.80BDNF methylation and depressive disorder in acute coronary syndrome: The K-DEPACS and EsDEPACS studies. ( Ahn, Y; Bae, KY; Hong, YJ; Jeong, MH; Kang, HJ; Kim, JM; Kim, SW; Shin, IS; Stewart, R; Yoon, JS, 2015)

Research

Studies (28)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's2 (7.14)29.6817
2010's25 (89.29)24.3611
2020's1 (3.57)2.80

Authors

AuthorsStudies
Kim, JM17
Stewart, R11
Kang, HJ15
Kim, SY3
Kim, JW4
Lee, HJ2
Lee, JY2
Kim, SW17
Shin, IS17
Kim, MC2
Shin, HY2
Hong, YJ17
Ahn, Y16
Jeong, MH17
Yoon, JS17
Bae, KY15
Ahn, YK1
Berk, M2
Lee, YS1
Kim, JH2
Kim, HR1
Shin, MG1
Thombs, BD2
Ziegelstein, RC2
Zimmermann, FM1
El Farissi, M1
Tonino, PAL1
Rust, G1
Hjorthøj, CR1
Hansen, BH4
Hanash, JA4
Rasmussen, A4
Birket-Smith, M4
Jung, BO1
Kang, G1
Kim, JK1
Parthasarathy, S1
Shetty, S1
Combs, D1
Kang, H2
Tolentino, JC1
Schmidt, JJ1
Schmidt, GJ1
Mesquita, CT1
Schmidt, SL1
Moon, WJ1
Carney, RM1
Freedland, KE1
Hansen, JF3
Andersen, NL1
Nielsen, OW2

Clinical Trials (4)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Efficacy and Safety of Escitalopram in the Treatment of Depressive Patients With Acute Coronary Artery Syndrome: A Double-blind Placebo-controlled Trial[NCT00419471]Phase 4300 participants (Actual)Interventional2007-05-31Completed
Effect of Acupressure on Pain, Anxiety and Vital Signs in Patients With Coronary Angiography: A Randomized Controlled Study[NCT05082506]105 participants (Anticipated)Interventional2021-12-15Not yet recruiting
Mindfulness-Based Cognitive Therapy Delivered Via Group Videoconferencing for Acute Coronary Syndrome Patients With Elevated Depression Symptoms[NCT03878160]27 participants (Actual)Interventional2018-07-01Completed
A Double-Blind, Placebo-Controlled Study of Escitalopram in the Prevention of Depression in Patients With Acute Coronary Syndrome[NCT00140257]Phase 4240 participants (Actual)Interventional2004-11-30Active, not recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trial Outcomes

Interpersonal Reactivity Index (IRI)

This is a 14-item scale that measures empathy. The scoring scale ranges from 0, does not describe me well, to 4, describes me very well. The score values range from 0-56, where high values represent higher levels of empathy and lower values represent lower levels of empathy. Data collection for this measurement is cross-sectional, and is performed during one, 30-90 minute time interval. (NCT03878160)
Timeframe: 30-90-minute study session

Interventionunits on a scale (Median)
Women and Men, <2 Years, Individual Interview41
Women and Men, >2 Years, Individual Interview39
Women and Men, Lifetime History of ACS, Individual Interview45

Medical Outcomes Study - Specific Adherence Scale (MOS- SAS)

This is a 3-item scale that measures health behaviors. The scoring scale ranges from 1, none of the time, to 6, all of the time. The scoring values range from 3-18, where higher values represent good health behavior and lower values represent poor health behavior. Data collection for this measurement is cross-sectional, and is performed during one, 30-90 minute time interval. (NCT03878160)
Timeframe: 30-90-minute study session

Interventionunits on a scale (Median)
Women and Men, <2 Years, Individual Interview11
Women and Men, >2 Years, Individual Interview10
Women and Men, Lifetime History of ACS, Individual Interview13

Patient Health Questionnaire-9 (PHQ-9)

This is a 9-item scale that measures depression. The scoring scale ranges from 0, not at all, to 3, nearly every day. The scoring values range from 0-18, where high values represent higher levels of depression and lower values represent lower levels of depression. Data collection for this measurement is cross-sectional, and is performed during one, 30-90 minute time interval. (NCT03878160)
Timeframe: 30-90-minute study session

Interventionunits on a scale (Median)
Women and Men, <2 Years, Individual Interview10.5
Women and Men, >2 Years, Individual Interview16
Women and Men, Lifetime History of ACS, Individual Interview1.5

Patient Reported Outcome Measurement Information System-Physical Function (PROMIS-29-PF)

This is a 4-item scale that measures and evaluates physical health. The scoring scale ranges from 5, without any difficulty, to 1, unable to do. The scoring values range from 4-20, where high values represent good physical function and low values represent poor physical function. Data collection for this measurement is cross-sectional, and is performed during one, 30-90 minute time interval. (NCT03878160)
Timeframe: 30-90-minute study session

Interventionunits on a scale (Median)
Women and Men, <2 Years, Individual Interview18
Women and Men, >2 Years, Individual Interview12
Women and Men, Lifetime History of ACS, Individual Interview20

Perceived Stress Scale-4 (PSS-4)

This is a 4-item scale that measures stress. The scoring scale ranges from 0,never, to 4, very often. The scale values range from 0-16 with higher values representing higher levels of individual stress and lower values representing lower levels of individual stress. Data collection for this measurement is cross-sectional, and is performed during one, 30-90 minute time interval. (NCT03878160)
Timeframe: 30-90-minute study session

Interventionunits on a scale (Median)
Women and Men, <2 Years, Individual Interview12
Women and Men, >2 Years, Individual Interview14
Women and Men, Lifetime History of ACS, Individual Interview6

Positive Affect Negative Affect Schedule (PANAS)

This is a 20-question scale, composed of 2, 10-item scales that measure positive and negative affect. The scoring scale ranges from 1, very slightly or not at all, to 5, extremely. For this study, we will only use the positive affect sub-scale. The scale values for the positive affect sub-scale range from 10-50. Higher values on the positive affect scale represent higher levels of positive affect, whereas, lower values on the negative affect scale represent lower levels of positive affect. Data collection for this measurement is cross-sectional, and is performed during one, 30-90 minute time interval. (NCT03878160)
Timeframe: 30-90-minute study session

Interventionunits on a scale (Median)
Women and Men, <2 Years, Individual Interview22
Women and Men, >2 Years, Individual Interview26
Women and Men, Lifetime History of ACS, Individual Interview34

Rumination Response Scale (RRS)

This is a 22-item scale that measures rumination. The scoring scale ranges from 1,almost never, to 4, almost always. The score values range from 22 to 88, where higher values represent higher levels of rumination and lower values represent lower levels of rumination. Data collection for this measurement is cross-sectional, and is performed during one, 30-90 minute time interval. (NCT03878160)
Timeframe: 30-90-minute study session

Interventionunits on a scale (Median)
Women and Men, <2 Years, Individual Interview41
Women and Men, >2 Years, Individual Interview51.5
Women and Men, Lifetime History of ACS, Individual Interview31

Self-Other Four Immeasurables (SOFI) Scale

This is a 16-item scale that measures views toward the self and others. This measure consists of four sub-scales with four items each. The sub-scales measure positive views toward self, negative views toward self, positive views toward others, and negative views toward other. Only the positive-other sub-scale was used. The scoring scale ranges from 1, very slightly or not at all to 5, extremely, with sub-scale scores ranging from 4-20. Higher values represent higher levels of positive feelings toward others, and lower values represent lower levels of positive feelings toward others. Data collection for this measurement is cross-sectional, and is performed during one, 30-90 minute time interval. (NCT03878160)
Timeframe: 30-90-minute study session

Interventionunits on a scale (Median)
Women and Men, <2 Years, Individual Interview15
Women and Men, >2 Years, Individual Interview12.5
Women and Men, Lifetime History of ACS, Individual Interview16

Short-Form-12 (SF-12)

This is a 12-item scale that measures health-related quality of life. The scoring scale from item 1 ranges from 1, excellent to 5, poor. The scoring scale for items 2 and 3 ranges from 1, limit you a lot to 3, not limit you at all. The scoring scale for questions 5-7 is represented by 1, yes or 2, no. The scoring scale for item 8 ranges from 1, not at all, to 5, extremely. The scoring scale for items 9-11 ranges from 1, all of the time, to 6, none of the time. The scoring scale for item 12 ranges from 1, all of the time to 5, none of the time. The total scoring values range from 12- 47, where higher values represent a higher quality of life and lower values represent a lower quality of life. Data collection for this measurement is cross-sectional, and is performed during one, 30-90 minute time interval. (NCT03878160)
Timeframe: 30-90-minute study session

Interventionunits on a scale (Median)
Women and Men, <2 Years, Individual Interview26
Women and Men, >2 Years, Individual Interview22
Women and Men, Lifetime History of ACS, Individual Interview40

Five Factor Mindfulness Questionnaire- 15 Item (FFMQ-15)

This is a 15-item measure that measures mindfulness. This scale has five sub-scales: observing, describing, acting with awareness, accepting without judgment, and non-reactivity. The scoring scale ranges from 1, never or very rarely true to 5, very often or always true. Scale values range from 3-15 for each sub-scale, with higher values representing greater levels of individual mindfulness and lower values representing lowers levels of individual mindfulness. There is no total score for the measure; only individual sub-scales are reported. Data collection for this measurement is cross-sectional, and is collected during one, 30-90 minute time interval. (NCT03878160)
Timeframe: 30-90-minute study session

,,
Interventionunits on a scale (Median)
ObservingDescribingActing with awarenessAccepting without judgmentNonreactivity
Women and Men, <2 Years, Individual Interview811111111
Women and Men, >2 Years, Individual Interview99989.5
Women and Men, Lifetime History of ACS, Individual Interview1013101414

Number of Participants Reporting Changes After ACS

This portion of the individual interview will focus on exploring changes experienced after an ACS, such as psychosocial changes and health behavior changes. Participants were individually interviewed via telephone using a semi-structured interview guide. Three independent coders conducted qualitative thematic analysis and results were analyzed within each group. The identified themes are reported, and the criteria used to determine the outcome measure is the number of participants who endorsed each theme. (NCT03878160)
Timeframe: one 30-90-minute session

,,
Interventionparticipants (Number)
Positive health behavior changesAdaptive perspectivesEmotional improvementsSocial improvementsActivity limitationsNegative physical symptomsEmotional problemsSocial problemsHealth behavior challenges
Women and Men, <2 Years, Individual Interview310155332
Women and Men, >2 Years, Individual Interview301078825
Women and Men, Lifetime History of ACS, Individual Interview1051546640

Number of Participants With Perspectives on Blood Spot Data Collection

This portion of the individual interview will focus on exploring ACS patients who had perspectives on participating in a remote dried blood spot procedure. Participants were individually interviewed via telephone using a semi-structured interview guide. Three independent coders conducted qualitative thematic analysis and results were analyzed within each group. The criteria used to determine the outcome measure is the number of participants upon interview who reported any type of perspective on participating in a remote dried blood spot procedure (self-collection of dried blood spot via finger-prick). Please note that the number of perspectives reported for each theme can exceed the number of people per group because each participant reported multiple perspectives (e.g., both pros and cons of videoconferencing). (NCT03878160)
Timeframe: one 30-90-minute session

,,
Interventionparticipants (Number)
Willing to complete DBSWould need trainingWould want more information about the rationale
Women and Men, <2 Years, Individual Interview525
Women and Men, >2 Years, Individual Interview754
Women and Men, Lifetime History of ACS, Individual Interview826

Number of Participants With Perspectives on MBCT

This portion of the individual interview will focus on exploring patients' perspectives toward an MBCT treatment approach. Participants were individually interviewed via telephone using a semi-structured interview guide. Three independent coders conducted qualitative thematic analysis and results were analyzed within each group. The identified themes are reported, and the criteria used to determine the outcome measure is the number of participants who endorsed each theme. (NCT03878160)
Timeframe: one 30-90-minute session

,,
Interventionparticipants (Number)
Willing to get helpWilling to participate in a group programPositive reaction to mindfulness
Women and Men, <2 Years, Individual Interview334
Women and Men, >2 Years, Individual Interview867
Women and Men, Lifetime History of ACS, Individual Interview887

Number of Participants With Perspectives on Videoconferencing

This portion of the individual interview will focus on exploring perspectives regarding videoconferencing intervention delivery. Participants were individually interviewed via telephone using a semi-structured interview guide. Three independent coders conducted qualitative thematic analysis and results were analyzed within each group. Identified themes are reported, and the criteria used to determine the outcome measure is the number of participants upon interview who reported expressed each theme. (NCT03878160)
Timeframe: one 30-90-minute session

,,
Interventionparticipants (Number)
Willing to try videoconferencingLogistical benefitsSocial benefitsTechnology limitationsSocial limitations
Women and Men, <2 Years, Individual Interview35222
Women and Men, >2 Years, Individual Interview75151
Women and Men, Lifetime History of ACS, Individual Interview87124

Reviews

2 reviews available for citalopram and Acute Coronary Syndrome

ArticleYear
Interactions between pro-inflammatory cytokines and statins on depression in patients with acute coronary syndrome.
    Progress in neuro-psychopharmacology & biological psychiatry, 2018, Jan-03, Volume: 80, Issue:Pt C

    Topics: Acute Coronary Syndrome; Citalopram; Cytokines; Depressive Disorder; Double-Blind Method; Female; Hu

2018
Treatment-resistant depression and mortality after acute coronary syndrome.
    The American journal of psychiatry, 2009, Volume: 166, Issue:4

    Topics: Acute Coronary Syndrome; Antidepressive Agents; Bupropion; Citalopram; Cognitive Behavioral Therapy;

2009

Trials

18 trials available for citalopram and Acute Coronary Syndrome

ArticleYear
Effect of Escitalopram vs Placebo Treatment for Depression on Long-term Cardiac Outcomes in Patients With Acute Coronary Syndrome: A Randomized Clinical Trial.
    JAMA, 2018, 07-24, Volume: 320, Issue:4

    Topics: Acute Coronary Syndrome; Adult; Aged; Antidepressive Agents, Second-Generation; Citalopram; Depressi

2018
Social support deficit and depression treatment outcomes in patients with acute coronary syndrome: Findings from the EsDEPACS study.
    International journal of psychiatry in medicine, 2019, Volume: 54, Issue:1

    Topics: Acute Coronary Syndrome; Aged; Antidepressive Agents; Citalopram; Depression; Diagnostic and Statist

2019
Methylation of the glucocorticoid receptor gene associated with depression in patients with acute coronary syndrome.
    Psychoneuroendocrinology, 2019, Volume: 101

    Topics: Acute Coronary Syndrome; Adult; Aged; Antidepressive Agents; Citalopram; CpG Islands; Depression; De

2019
Prevention of depression in patients with acute coronary syndrome (DECARD) randomized trial: effects on and by self-reported health.
    Early intervention in psychiatry, 2015, Volume: 9, Issue:5

    Topics: Acute Coronary Syndrome; Aged; Antidepressive Agents, Second-Generation; Citalopram; Depression; Dou

2015
Escitalopram treatment for depressive disorder following acute coronary syndrome: a 24-week double-blind, placebo-controlled trial.
    The Journal of clinical psychiatry, 2015, Volume: 76, Issue:1

    Topics: Acute Coronary Syndrome; Aged; Citalopram; Depressive Disorder; Double-Blind Method; Female; Humans;

2015
Effects of depression co-morbidity and treatment on quality of life in patients with acute coronary syndrome: the Korean depression in ACS (K-DEPACS) and the escitalopram for depression in ACS (EsDEPACS) study.
    Psychological medicine, 2015, Volume: 45, Issue:8

    Topics: Acute Coronary Syndrome; Citalopram; Comorbidity; Depressive Disorder; Double-Blind Method; Female;

2015
Correlates and Escitalopram Treatment Effects on Sleep Disturbance in Patients with Acute Coronary Syndrome: K-DEPACS and EsDEPACS.
    Sleep, 2015, Jul-01, Volume: 38, Issue:7

    Topics: Acute Coronary Syndrome; Adolescent; Adult; Age Factors; Aged; Aged, 80 and over; Aging; Citalopram;

2015
Predictors of depressive disorder following acute coronary syndrome: Results from K-DEPACS and EsDEPACS.
    Journal of affective disorders, 2015, Aug-01, Volume: 181

    Topics: Acute Coronary Syndrome; Adolescent; Adult; Aged; Aged, 80 and over; Citalopram; Comorbidity; Depres

2015
Effects of depression screening on psychiatric outcomes in patients with acute coronary syndrome: Findings from the K-DEPACS and EsDEPACS studies.
    International journal of cardiology, 2015, Volume: 190

    Topics: Acute Coronary Syndrome; Aged; Citalopram; Depressive Disorder; Diagnostic and Statistical Manual of

2015
The use of statins for the treatment of depression in patients with acute coronary syndrome.
    Translational psychiatry, 2015, Aug-18, Volume: 5

    Topics: Acute Coronary Syndrome; Citalopram; Cohort Studies; Depressive Disorder; Double-Blind Method; Femal

2015
BDNF methylation and depressive disorder in acute coronary syndrome: The K-DEPACS and EsDEPACS studies.
    Psychoneuroendocrinology, 2015, Volume: 62

    Topics: Acute Coronary Syndrome; Adolescent; Adult; Aged; Aged, 80 and over; Antidepressive Agents; Brain-De

2015
BDNF val66met polymorphism and depressive disorders in patients with acute coronary syndrome.
    Journal of affective disorders, 2016, Volume: 194

    Topics: Acute Coronary Syndrome; Aged; Alleles; Antidepressive Agents; Brain-Derived Neurotrophic Factor; Ci

2016
Influences of the Big Five personality traits on the treatment response and longitudinal course of depression in patients with acute coronary syndrome: A randomised controlled trial.
    Journal of affective disorders, 2016, Volume: 203

    Topics: Acute Coronary Syndrome; Adult; Aged; Antidepressive Agents, Second-Generation; Citalopram; Depressi

2016
Determinants and escitalopram treatment effects on suicidal ideation in patients with acute coronary syndrome: Findings from the K-DEPACS and EsDEPACS studies.
    International journal of cardiology, 2016, Sep-15, Volume: 219

    Topics: Acute Coronary Syndrome; Aged; Antidepressive Agents, Second-Generation; Anxiety; Citalopram; Cross-

2016
Predictive value of homocysteine for depression after acute coronary syndrome.
    Oncotarget, 2016, Oct-18, Volume: 7, Issue:42

    Topics: Acute Coronary Syndrome; Adult; Aged; Antidepressive Agents; Biomarkers, Tumor; Citalopram; Depressi

2016
Rationale, design and methodology of a double-blind, randomized, placebo-controlled study of escitalopram in prevention of Depression in Acute Coronary Syndrome (DECARD).
    Trials, 2009, Apr-07, Volume: 10

    Topics: Acute Coronary Syndrome; Antidepressive Agents, Second-Generation; Citalopram; Depression; Double-Bl

2009
Effects of escitalopram in prevention of depression in patients with acute coronary syndrome (DECARD).
    Journal of psychosomatic research, 2012, Volume: 72, Issue:1

    Topics: Acute Coronary Syndrome; Aged; Antidepressive Agents; Citalopram; Depression; Double-Blind Method; F

2012
Cardiovascular safety of one-year escitalopram therapy in clinically nondepressed patients with acute coronary syndrome: results from the DEpression in patients with Coronary ARtery Disease (DECARD) trial.
    Journal of cardiovascular pharmacology, 2012, Volume: 60, Issue:4

    Topics: Acute Coronary Syndrome; Aged; Cardiovascular Diseases; Citalopram; Depression; Double-Blind Method;

2012

Other Studies

8 other studies available for citalopram and Acute Coronary Syndrome

ArticleYear
Long-term cardiac outcomes of depression screening, diagnosis and treatment in patients with acute coronary syndrome: the DEPACS study-ADDENDUM.
    Psychological medicine, 2021, Volume: 51, Issue:6

    Topics: Acute Coronary Syndrome; Citalopram; Depression; Depressive Disorder; Humans

2021
Cardiac Outcomes After Treatment for Depression in Patients With Acute Coronary Syndrome.
    JAMA, 2018, 11-27, Volume: 320, Issue:20

    Topics: Acute Coronary Syndrome; Citalopram; Depression; Depressive Disorder; Heart; Humans

2018
Cardiac Outcomes After Treatment for Depression in Patients With Acute Coronary Syndrome.
    JAMA, 2018, 11-27, Volume: 320, Issue:20

    Topics: Acute Coronary Syndrome; Citalopram; Depression; Depressive Disorder; Heart; Humans

2018
Cardiac Outcomes After Treatment for Depression in Patients With Acute Coronary Syndrome.
    JAMA, 2018, 11-27, Volume: 320, Issue:20

    Topics: Acute Coronary Syndrome; Citalopram; Depression; Depressive Disorder; Heart; Humans

2018
Modifying effects of depression on the association between BDNF methylation and prognosis of acute coronary syndrome.
    Brain, behavior, and immunity, 2019, Volume: 81

    Topics: Acute Coronary Syndrome; Adult; Aged; Antidepressive Agents, Second-Generation; Brain-Derived Neurot

2019
Mend the Mind and Mind the "MCC".
    Sleep, 2015, Jul-01, Volume: 38, Issue:7

    Topics: Acute Coronary Syndrome; Citalopram; Depressive Disorder; Female; Humans; Male; Sleep Wake Disorders

2015
Mental Stress-Induced Myocardial Ischemia Related to Generalized Anxiety Disorder in a Patient With Acute Coronary Syndrome and Normal Coronary Arteries.
    Clinical nuclear medicine, 2016, Volume: 41, Issue:11

    Topics: Acute Coronary Syndrome; Anxiety Disorders; Citalopram; Computed Tomography Angiography; Coronary An

2016
When prevention is a bad idea: problems with the DECARD trial and the premise behind it.
    Journal of psychosomatic research, 2012, Volume: 72, Issue:5

    Topics: Acute Coronary Syndrome; Antidepressive Agents; Citalopram; Depressive Disorder; Humans; Randomized

2012