citalopram has been researched along with ADDH in 8 studies
Citalopram: A furancarbonitrile that is one of the serotonin uptake inhibitors used as an antidepressant. The drug is also effective in reducing ethanol uptake in alcoholics and is used in depressed patients who also suffer from TARDIVE DYSKINESIA in preference to tricyclic antidepressants, which aggravate dyskinesia.
citalopram : A racemate comprising equimolar amounts of (R)-citalopram and its enantiomer, escitalopram. It is used as an antidepressant, although only escitalopram is active.
1-[3-(dimethylamino)propyl]-1-(4-fluorophenyl)-1,3-dihydro-2-benzofuran-5-carbonitrile : A nitrile that is 1,3-dihydro-2-benzofuran-5-carbonitrile in which one of the hydrogens at position 1 is replaced by a p-fluorophenyl group, while the other is replaced by a 3-(dimethylamino)propyl group.
Excerpt | Relevance | Reference |
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" In the present study, we have examined the effect of lisdexamfetamine dimesylate (LDX), an amphetamine pro-drug that is approved for the treatment of ADHD on acetylcholine and histamine efflux in pre-frontal cortex and hippocampus alone and in combination with the anti-depressant s-citalopram." | 1.42 | Effects of lisdexamfetamine alone and in combination with s-citalopram on acetylcholine and histamine efflux in the rat pre-frontal cortex and ventral hippocampus. ( Folgering, JH; Heins, MS; Hutson, PH, 2015) |
"Citalopram was being investigated in three ongoing clinical trials lasting 8-24 weeks in 423 patients aged 7-18 years." | 1.35 | Opening the white boxes: the licensing documentation of efficacy and safety of psychotropic medicines for children. ( Aagaard, L; Hansen, EH; Thirstrup, S, 2009) |
"Thirty youth with major depressive disorder (MDD) and 23 control youth reported on caffeine use, sleep, and affect in their natural environment using ecological momentary assessment at baseline and over 8 weeks, while MDD youth received treatment." | 1.35 | Caffeine consumption, sleep, and affect in the natural environments of depressed youth and healthy controls. ( Axelson, DA; Birmaher, B; Dahl, RE; Forbes, EE; Ryan, ND; Semel, M; Silk, JS; Whalen, DJ, 2008) |
"The diagnoses of ADHD and tic disorder were based on clinical observations and standardized rating scales." | 1.34 | Tic exacerbation and precipitation during atomoxetine treatment in two children with attention-deficit hyperactivity disorder. ( Harris, DK; Párraga, HC; Párraga, MI, 2007) |
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 0 (0.00) | 18.7374 |
1990's | 0 (0.00) | 18.2507 |
2000's | 4 (50.00) | 29.6817 |
2010's | 4 (50.00) | 24.3611 |
2020's | 0 (0.00) | 2.80 |
Authors | Studies |
---|---|
Chon, MW | 1 |
Lee, J | 1 |
Chung, S | 1 |
Kim, Y | 1 |
Kim, HW | 1 |
Santos-Cubiñá, J | 1 |
Torres-Rodríguez, A | 1 |
Castaing-Lespier, PA | 1 |
Sabaté, N | 1 |
Torres-Martin, A | 1 |
Carlo, S | 1 |
Hutson, PH | 1 |
Heins, MS | 1 |
Folgering, JH | 1 |
Aagaard, L | 1 |
Thirstrup, S | 1 |
Hansen, EH | 1 |
Herrera-Guzmán, I | 1 |
Herrera-Abarca, JE | 1 |
Gudayol-Ferré, E | 1 |
Herrera-Guzmán, D | 1 |
Gómez-Carbajal, L | 1 |
Peña-Olvira, M | 1 |
Villuendas-González, E | 1 |
Joan, GO | 1 |
Woolley, JB | 1 |
Heyman, I | 1 |
Whalen, DJ | 1 |
Silk, JS | 1 |
Semel, M | 1 |
Forbes, EE | 1 |
Ryan, ND | 1 |
Axelson, DA | 1 |
Birmaher, B | 1 |
Dahl, RE | 1 |
Párraga, HC | 1 |
Párraga, MI | 1 |
Harris, DK | 1 |
Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
---|---|---|---|---|---|---|---|
A Randomized, Single Blind, Controlled, Longitudinal Study of the Effects of Venlafaxine Hydrochloride Capsules on the Language Function of Stroke Patients With Subcortical Aphasia Using fMRI[NCT03588572] | 43 participants (Actual) | Interventional | 2018-08-01 | Completed | |||
The Language Functional Reorganization Following Subcortical Cerebral Infarction: A Longitudinal fMRI Study[NCT03668132] | 80 participants (Actual) | Observational | 2016-01-19 | Completed | |||
[information is prepared from clinicaltrials.gov, extracted Sep-2024] |
This test mainly assesses the ability of picture name of participants.we used a program for displaying named pictures on a computer screen (60 photos in total, of which 20 were Chinese celebrity faces). Each image was displayed in 3 seconds, and 1 point was correctly named for an image.The faces of celebrities were selected from the picture database of Chinese celebrities in the State Key Laboratory of Cognitive Neuroscience and Learning at Beijing Normal University.Score fluctuation is 0-60 points, the higher the score, the better the ability of picture name. (NCT03588572)
Timeframe: This is an outcome measure to assess the improvement of language function from onset to 3 months after treatment. Thus, participates will undergo this assessment on the first days (V1), 28±3 days (V2), and 90±3 days (V3) after randomization.
Intervention | score on a scale (Mean) | ||
---|---|---|---|
Visitation 1 | Visitation 2 | Visitation 3 | |
Controlled Group | 38.31 | 43.31 | 48.31 |
Venlafaxine Group | 39.19 | 46.75 | 52.25 |
This test mainly assesses spontaneous speech fluency of participants.It requires participants name as many food names as possible within one minute, and each correct one to give one point.The higher the score, the better the language function. (NCT03588572)
Timeframe: This is an outcome measure to assess the improvement of language function from onset to 3 months after treatment. Thus, participates will undergo this assessment on the first days (V1), 28±3 days (V2), and 90±3 days (V3) after randomization.
Intervention | score on a scale (Mean) | ||
---|---|---|---|
Visitation 1 | Visitation 2 | Visitation 3 | |
Controlled Group | 5.75 | 8.13 | 10.81 |
Venlafaxine Group | 5.31 | 9.31 | 12.69 |
The main outcome measure for this scale is Aphasia Quotient(AQ) which mainly tests the ability of spontaneous speech, oral comprehension, repetition, and naming, and reflects the severity of aphasia, and can be used as a reliable indicator to evaluate the improvement and deterioration of aphasia. Score fluctuation is 0-100 points, the normal value is 98.4-100 points, AQ<93.8 can be judged as language dysfunction. (NCT03588572)
Timeframe: This is an outcome measure to assess the improvement of language function from onset to 3 months after treatment. Thus, participates will undergo this assessment on the first days (V1), 28±3 days (V2), and 90±3 days (V3) after randomization.
Intervention | score on a scale (Mean) | ||
---|---|---|---|
Visitation 1 | Visitation 2 | Visitation 3 | |
Controlled Group | 78.60 | 83.51 | 88.55 |
Venlafaxine Group | 78.16 | 88.24 | 94.23 |
The Hamilton Anxiety Rating Scale (HAMA) is a widely used and well-validated tool for measuring the severity of a patient's anxiety. The HAMA is composed of 14 items and takes 15-20 minutes to complete the interview and score the results. Each item is scored on a 5-point scale, ranging from 0=not present to 4=severe.HAMA Scoring Instructions:0-8=Normal, 8-13= Possible Anxiety, 14-17 = Mild Anxiety, 18-24 = Moderate Anxiety, 25-30 = Severe Anxiety(i.e.,the higher the score, the greater the likelihood of anxiety). (NCT03588572)
Timeframe: We must determine that the participant is not in anxiety at each follow-up. Thus, participates will undergo this assessment on the first days (V1), 28±3 days (V2), and 90±3 days (V3) after randomization.
Intervention | score on a scale (Mean) | ||
---|---|---|---|
Visitation 1 | Visitation 2 | Visitation 3 | |
Controlled Group | 4.63 | 4.00 | 3.25 |
Venlafaxine Group | 4.88 | 4.13 | 3.56 |
The Hamilton Depression Rating Scale (HAMD) has proven useful for many years as a way of determining a patient's level of depression before, during, and after treatment. It generally takes 15-20 minutes to complete the interview and score the results. Eight items are scored on a 5-point scale, ranging from 0 = not present to 4 = severe. Nine items are scored from 0-2. HAMD Scoring Instructions:0-7=Normal, 8-13 = Mild Depression, 14-18 = Moderate Depression, 19-22 = Severe Depression, ≥ 23 = Very Severe Depression(i.e.,Minimum 0 points and maximum 50 points, the higher the score, the greater the likelihood of depression). (NCT03588572)
Timeframe: We must determine that the participant is not in depression at each follow-up. Thus, participates will undergo this assessment on the first days (V1), 28±3 days (V2), and 90±3 days (V3) after randomization.
Intervention | score on a scale (Mean) | ||
---|---|---|---|
Visitation 1 | Visitation 2 | Visitation 3 | |
Controlled Group | 5.25 | 4.63 | 3.88 |
Venlafaxine Group | 5.63 | 4.94 | 4.06 |
The Mini-Mental State Examination (MMSE) is a 30-point questionnaire that is used extensively in clinical and research settings to measure cognitive impairment. Administration of the test takes between 5 and 10 minutes. The MMSE test includes simple questions and problems in a number of areas: the time and place of the test, repeating lists of words, arithmetic such as the serial sevens, language use and comprehension, and basic motor skills. Any score greater than or equal to 24 points (out of 30) indicates a normal cognition. Below this, scores can indicate severe (≤9 points), moderate (10-18 points) or mild (19-23 points) cognitive impairment.The raw score may also need to be corrected for educational attainment and age. (NCT03588572)
Timeframe: We must determine that the participant is not in moderate or more cognitive impairment at each follow-up. Thus, participates will undergo this assessment on the first days (V1), 28±3 days (V2), and 90±3 days (V3) after randomization.
Intervention | score on a scale (Mean) | ||
---|---|---|---|
Visitation 1 | Visitation 2 | Visitation 3 | |
Controlled Group | 23.88 | 25.00 | 26.19 |
Venlafaxine Group | 23.81 | 25.38 | 26.38 |
8 other studies available for citalopram and ADDH
Article | Year |
---|---|
Prescription Pattern of Antidepressants for Children and Adolescents in Korea Based on Nationwide Data.
Topics: Adolescent; Antidepressive Agents; Attention Deficit Disorder with Hyperactivity; Child; Citalopram; | 2017 |
Exacerbation of mood symptoms associated to primary and secondary carnitine deficiency: a case report.
Topics: Adult; Antidepressive Agents; Antimanic Agents; Attention Deficit Disorder with Hyperactivity; Benzo | 2013 |
Effects of lisdexamfetamine alone and in combination with s-citalopram on acetylcholine and histamine efflux in the rat pre-frontal cortex and ventral hippocampus.
Topics: Acetylcholine; Animals; Antidepressive Agents, Second-Generation; Attention Deficit Disorder with Hy | 2015 |
Opening the white boxes: the licensing documentation of efficacy and safety of psychotropic medicines for children.
Topics: Adolescent; Adult; Attention Deficit Disorder with Hyperactivity; Child; Child, Preschool; Citalopra | 2009 |
Effects of selective serotonin reuptake and dual serotonergic-noradrenergic reuptake treatments on attention and executive functions in patients with major depressive disorder.
Topics: Adrenergic Uptake Inhibitors; Adult; Attention Deficit Disorder with Hyperactivity; Citalopram; Cogn | 2010 |
Effects of selective serotonin reuptake and dual serotonergic-noradrenergic reuptake treatments on attention and executive functions in patients with major depressive disorder.
Topics: Adrenergic Uptake Inhibitors; Adult; Attention Deficit Disorder with Hyperactivity; Citalopram; Cogn | 2010 |
Effects of selective serotonin reuptake and dual serotonergic-noradrenergic reuptake treatments on attention and executive functions in patients with major depressive disorder.
Topics: Adrenergic Uptake Inhibitors; Adult; Attention Deficit Disorder with Hyperactivity; Citalopram; Cogn | 2010 |
Effects of selective serotonin reuptake and dual serotonergic-noradrenergic reuptake treatments on attention and executive functions in patients with major depressive disorder.
Topics: Adrenergic Uptake Inhibitors; Adult; Attention Deficit Disorder with Hyperactivity; Citalopram; Cogn | 2010 |
Dexamphetamine for obsessive-compulsive disorder.
Topics: Anxiety Disorders; Attention Deficit Disorder with Hyperactivity; Central Nervous System Stimulants; | 2003 |
Caffeine consumption, sleep, and affect in the natural environments of depressed youth and healthy controls.
Topics: Adolescent; Affect; Anxiety Disorders; Attention Deficit Disorder with Hyperactivity; Beverages; Caf | 2008 |
Tic exacerbation and precipitation during atomoxetine treatment in two children with attention-deficit hyperactivity disorder.
Topics: Adrenergic Uptake Inhibitors; Antipsychotic Agents; Anxiety Disorders; Atomoxetine Hydrochloride; At | 2007 |