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cisapride and Tachycardia, Ventricular

cisapride has been researched along with Tachycardia, Ventricular in 6 studies

Cisapride: A substituted benzamide used for its prokinetic properties. It is used in the management of gastroesophageal reflux disease, functional dyspepsia, and other disorders associated with impaired gastrointestinal motility. (Martindale The Extra Pharmacopoeia, 31st ed)
cisapride : The amide resulting from formal condensation of 4-amino-5-chloro-2-methoxybenzoic acid with cis-1-[3-(4-fluorophenoxy)propyl]-3-methoxypiperidin-4-amine. It has been used (as its monohydrate or as its tartrate) for the treatment of gastro-oesophageal reflux disease and for non-ulcer dyspepsia, but its propensity to cause cardiac arrhythmias resulted in its complete withdrawal from many countries, including the U.K., and restrictions on its use elsewhere.

Tachycardia, Ventricular: An abnormally rapid ventricular rhythm usually in excess of 150 beats per minute. It is generated within the ventricle below the BUNDLE OF HIS, either as autonomic impulse formation or reentrant impulse conduction. Depending on the etiology, onset of ventricular tachycardia can be paroxysmal (sudden) or nonparoxysmal, its wide QRS complexes can be uniform or polymorphic, and the ventricular beating may be independent of the atrial beating (AV dissociation).

Research Excerpts

ExcerptRelevanceReference
"To evaluate the risk of serious ventricular arrhythmia (SVA) with cisapride use in the United States."7.71Serious ventricular arrhythmias among users of cisapride and other QT-prolonging agents in the United States. ( Cali, C; Enger, C; Walker, AM, 2002)
"The FDA analyzed reports of patients who developed QT prolongation, torsades de pointes, and ventricular arrhythmia in association with the use of cisapride to assess probable etiology and risk factors."7.71Postmarketing reports of QT prolongation and ventricular arrhythmia in association with cisapride and Food and Drug Administration regulatory actions. ( Corken, A; Gallo-Torres, H; Rodriguez, EM; Talarico, L; Wysowski, DK, 2001)
" Continuous 24-h ECG recording detected a ventricular tachycardia in torsades de pointes inducing a syncopal convulsive attack that seemed to be related to oral Cisapride assumption for dyspepsia."3.74An anorexic woman with convulsive loss of consciousness. Syncope or epileptic fits? ( Argiriadou, V; Attanasio, A; Diomedi, M; Sandri, G, 2007)
"To evaluate the risk of serious ventricular arrhythmia (SVA) with cisapride use in the United States."3.71Serious ventricular arrhythmias among users of cisapride and other QT-prolonging agents in the United States. ( Cali, C; Enger, C; Walker, AM, 2002)
"The FDA analyzed reports of patients who developed QT prolongation, torsades de pointes, and ventricular arrhythmia in association with the use of cisapride to assess probable etiology and risk factors."3.71Postmarketing reports of QT prolongation and ventricular arrhythmia in association with cisapride and Food and Drug Administration regulatory actions. ( Corken, A; Gallo-Torres, H; Rodriguez, EM; Talarico, L; Wysowski, DK, 2001)
"Drugs can cause cardiac arrhythmias in a number of clinical situations, and many of the implicated agents are used to treat non-cardiac conditions."2.40Drug-induced cardiac arrhythmias: incidence, prevention and management. ( Doig, JC, 1997)

Research

Studies (6)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's3 (50.00)18.2507
2000's3 (50.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Enger, C1
Cali, C1
Walker, AM1
Attanasio, A1
Argiriadou, V1
Sandri, G1
Diomedi, M1
Jenkins, IR1
Gibson, J1
Doig, JC1
RubĂ­n, JM1
de la Tassa, CM1
Arias, JC1
Wysowski, DK1
Corken, A1
Gallo-Torres, H1
Talarico, L1
Rodriguez, EM1

Reviews

1 review available for cisapride and Tachycardia, Ventricular

ArticleYear
Drug-induced cardiac arrhythmias: incidence, prevention and management.
    Drug safety, 1997, Volume: 17, Issue:4

    Topics: Amiodarone; Angiotensin-Converting Enzyme Inhibitors; Anti-Arrhythmia Agents; Anti-Infective Agents;

1997

Other Studies

5 other studies available for cisapride and Tachycardia, Ventricular

ArticleYear
Serious ventricular arrhythmias among users of cisapride and other QT-prolonging agents in the United States.
    Pharmacoepidemiology and drug safety, 2002, Volume: 11, Issue:6

    Topics: Adolescent; Adult; Age Distribution; Age Factors; Arrhythmias, Cardiac; Child; Child, Preschool; Cis

2002
An anorexic woman with convulsive loss of consciousness. Syncope or epileptic fits?
    International journal of cardiology, 2007, Mar-20, Volume: 116, Issue:2

    Topics: Adult; Anorexia; Cisapride; Diagnosis, Differential; Dyspepsia; Epilepsy; Female; Gastrointestinal A

2007
Cisapride, erythromycin and arrhythmia.
    Anaesthesia and intensive care, 1996, Volume: 24, Issue:6

    Topics: Adult; Anti-Bacterial Agents; Cisapride; Drug Interactions; Erythromycin; Humans; Male; Piperidines;

1996
Cisapride can make Prinzmetal angina worse.
    International journal of cardiology, 1998, Volume: 65, Issue:3

    Topics: Angina Pectoris, Variant; Cisapride; Diagnostic Errors; Gastrointestinal Agents; Humans; Male; Middl

1998
Postmarketing reports of QT prolongation and ventricular arrhythmia in association with cisapride and Food and Drug Administration regulatory actions.
    The American journal of gastroenterology, 2001, Volume: 96, Issue:6

    Topics: Adverse Drug Reaction Reporting Systems; Arrhythmias, Cardiac; Cisapride; Contraindications; Drug an

2001