cisapride has been researched along with Spinal Cord Injuries in 13 studies
Cisapride: A substituted benzamide used for its prokinetic properties. It is used in the management of gastroesophageal reflux disease, functional dyspepsia, and other disorders associated with impaired gastrointestinal motility. (Martindale The Extra Pharmacopoeia, 31st ed)
cisapride : The amide resulting from formal condensation of 4-amino-5-chloro-2-methoxybenzoic acid with cis-1-[3-(4-fluorophenoxy)propyl]-3-methoxypiperidin-4-amine. It has been used (as its monohydrate or as its tartrate) for the treatment of gastro-oesophageal reflux disease and for non-ulcer dyspepsia, but its propensity to cause cardiac arrhythmias resulted in its complete withdrawal from many countries, including the U.K., and restrictions on its use elsewhere.
Spinal Cord Injuries: Penetrating and non-penetrating injuries to the spinal cord resulting from traumatic external forces (e.g., WOUNDS, GUNSHOT; WHIPLASH INJURIES; etc.).
| Excerpt | Relevance | Reference |
|---|---|---|
| "Treatment with cisapride (4 x 10 mg daily) was undertaken." | 5.27 | Effects of cisapride on constipation due to a neurological lesion. ( de Groot, GH; de Pagter, GF, 1988) |
| "The data suggest that cisapride might be a useful adjunctive measure in treating a subset of SCI patients with colonic inertia, but a larger study is needed before this can be routinely recommended." | 5.08 | The effect of cisapride on segmental colonic transit time in patients with spinal cord injury. ( Bauman, WA; Gaing, A; Geders, JM; Korsten, MA, 1995) |
| "Five studies reported the use of cisapride and tegaserod in people with spinal cord injuries or Parkinson's disease." | 4.90 | Management of faecal incontinence and constipation in adults with central neurological diseases. ( Cody, JD; Coggrave, M; Norton, C, 2014) |
| "Five studies reported the use of cisapride and tegaserod in people with spinal cord injuries or Parkinson's disease." | 4.89 | Management of faecal incontinence and constipation in adults with central neurological diseases. ( Coggrave, M; Norton, C, 2013) |
| " Cisapride does not seem to have clinically useful effects in people with spinal cord injuries (three trials)." | 4.83 | Management of faecal incontinence and constipation in adults with central neurological diseases. ( Coggrave, M; Norton, C; Wiesel, PH, 2006) |
| " Cisapride does not seem to have clinically useful effects in people with spinal cord injuries (two trials)." | 4.81 | Management of faecal incontinence and constipation in adults with central neurological diseases. ( Brazzelli, M; Norton, C; Wiesel, PH, 2001) |
| "Treatment with cisapride (4 x 10 mg daily) was undertaken." | 1.27 | Effects of cisapride on constipation due to a neurological lesion. ( de Groot, GH; de Pagter, GF, 1988) |
| "Treatment with Cisapride (R 51 619, Janssen Pharmaceutica) was undertaken in an attempt to increase colonic motility and to reduce urinary retention." | 1.27 | Treatment with cisapride of the gastrointestinal and urological sequelae of spinal cord transection: case report. ( Brassinne, A; Etienne, M; Verlinden, M, 1988) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (15.38) | 18.7374 |
| 1990's | 6 (46.15) | 18.2507 |
| 2000's | 3 (23.08) | 29.6817 |
| 2010's | 2 (15.38) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Coggrave, M | 3 |
| Norton, C | 4 |
| Cody, JD | 1 |
| Wiesel, PH | 2 |
| Geders, JM | 1 |
| Gaing, A | 1 |
| Bauman, WA | 1 |
| Korsten, MA | 2 |
| Carone, R | 1 |
| Vercelli, D | 1 |
| Bertapelle, P | 1 |
| Meier, C | 1 |
| Hess, C | 1 |
| Meier-Abt, PJ | 1 |
| Krähenbühl, S | 1 |
| Wyndaele, JJ | 1 |
| Van Kerrebroeck, P | 1 |
| Longo, WE | 1 |
| Woolsey, RM | 1 |
| Vernava, AM | 1 |
| Virgo, KS | 1 |
| McKirgan, L | 1 |
| Johnson, FE | 1 |
| Correa, GI | 1 |
| Rotter, KP | 1 |
| Brazzelli, M | 1 |
| Rajendran, SK | 1 |
| Reiser, JR | 1 |
| Bauman, W | 1 |
| Zhang, RL | 1 |
| Gordon, SK | 1 |
| de Groot, GH | 1 |
| de Pagter, GF | 1 |
| Etienne, M | 1 |
| Verlinden, M | 1 |
| Brassinne, A | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Neurogenic Bowel Dysfunction: Evaluation of the Effects of Osteopathic Manipulative Treatment in People With Central Nervous System Injury[NCT04127617] | 70 participants (Anticipated) | Interventional | 2019-10-28 | Recruiting | |||
| Automatic Colon-specific Massage With MOWOOT Medical Device to Treat Chronic Constipation in Adults[NCT04262752] | 100 participants (Actual) | Interventional | 2018-01-11 | Completed | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
4 reviews available for cisapride and Spinal Cord Injuries
| Article | Year |
|---|---|
Management of faecal incontinence and constipation in adults with central neurological diseases.
Topics: Adult; Central Nervous System Diseases; Cisapride; Constipation; Fecal Incontinence; Gastrointestina | 2013 |
Management of faecal incontinence and constipation in adults with central neurological diseases.
Topics: Central Nervous System Diseases; Cisapride; Constipation; Fecal Incontinence; Gastrointestinal Agent | 2014 |
Management of faecal incontinence and constipation in adults with central neurological diseases.
Topics: Central Nervous System Diseases; Cisapride; Constipation; Fecal Incontinence; Gastrointestinal Agent | 2006 |
Management of faecal incontinence and constipation in adults with central neurological diseases.
Topics: Central Nervous System Diseases; Cisapride; Constipation; Fecal Incontinence; Gastrointestinal Agent | 2001 |
3 trials available for cisapride and Spinal Cord Injuries
| Article | Year |
|---|---|
The effect of cisapride on segmental colonic transit time in patients with spinal cord injury.
Topics: Adult; Aged; Cisapride; Colon; Constipation; Double-Blind Method; Gastrointestinal Transit; Humans; | 1995 |
The effects of 4 weeks treatment with cisapride on cystometric parameters in spinal cord injury patients. A double-blind, placebo controlled study.
Topics: Adolescent; Adult; Cisapride; Double-Blind Method; Drug Administration Schedule; Female; Humans; Mal | 1995 |
Gastrointestinal transit after spinal cord injury: effect of cisapride.
Topics: Adult; Aged; Cisapride; Double-Blind Method; Gastric Emptying; Gastrointestinal Transit; Humans; Mal | 1992 |
6 other studies available for cisapride and Spinal Cord Injuries
| Article | Year |
|---|---|
Effects of cisapride on anorectal and vesicourethral function in spinal cord injured patients.
Topics: Anal Canal; Cisapride; Female; Gastrointestinal Diseases; Gastrointestinal Transit; Humans; Male; Pi | 1993 |
[A clinical-pharmacological case (1). Action of cisapride (Prepulsid) on bladder function].
Topics: Aged; Cisapride; Constipation; Humans; Male; Parasympathomimetics; Piperidines; Spinal Cord Injuries | 1996 |
Cisapride for constipation in spinal cord injured patients: a preliminary report.
Topics: Cisapride; Colostomy; Constipation; Gastrointestinal Motility; Gastrointestinal Transit; Humans; Man | 1995 |
Clinical evaluation and management of neurogenic bowel after spinal cord injury.
Topics: Adult; Cisapride; Colonic Diseases; Dietary Fiber; Dioctyl Sulfosuccinic Acid; Female; Gastrointesti | 2000 |
Effects of cisapride on constipation due to a neurological lesion.
Topics: Adult; Chronic Disease; Cisapride; Constipation; Dose-Response Relationship, Drug; Gastrointestinal | 1988 |
Treatment with cisapride of the gastrointestinal and urological sequelae of spinal cord transection: case report.
Topics: Bisacodyl; Cisapride; Constipation; Drug Administration Schedule; Drug Therapy, Combination; Humans; | 1988 |