cisapride has been researched along with Scleroderma, Systemic in 8 studies
Cisapride: A substituted benzamide used for its prokinetic properties. It is used in the management of gastroesophageal reflux disease, functional dyspepsia, and other disorders associated with impaired gastrointestinal motility. (Martindale The Extra Pharmacopoeia, 31st ed)
cisapride : The amide resulting from formal condensation of 4-amino-5-chloro-2-methoxybenzoic acid with cis-1-[3-(4-fluorophenoxy)propyl]-3-methoxypiperidin-4-amine. It has been used (as its monohydrate or as its tartrate) for the treatment of gastro-oesophageal reflux disease and for non-ulcer dyspepsia, but its propensity to cause cardiac arrhythmias resulted in its complete withdrawal from many countries, including the U.K., and restrictions on its use elsewhere.
Scleroderma, Systemic: A chronic multi-system disorder of CONNECTIVE TISSUE. It is characterized by SCLEROSIS in the SKIN, the LUNGS, the HEART, the GASTROINTESTINAL TRACT, the KIDNEYS, and the MUSCULOSKELETAL SYSTEM. Other important features include diseased small BLOOD VESSELS and AUTOANTIBODIES. The disorder is named for its most prominent feature (hard skin), and classified into subsets by the extent of skin thickening: LIMITED SCLERODERMA and DIFFUSE SCLERODERMA.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Constipation is common in patients with PSS." | 2.70 | Effects of cisapride on colonic transit in patients with progressive systemic sclerosis. ( Chen, DY; Chen, YH; Hsieh, TY; Lan, JL; Lin, WY; Wang, SJ, 2002) |
| "In most patients with progressive systemic sclerosis (PSS) the oesophagus is affected." | 2.70 | Effects of cisapride on oesophageal transit of solids in patients with progressive systemic sclerosis. ( Chen, DY; Chen, YH; Hsieh, TY; La, JL; Lin, WY; Wang, SJ, 2002) |
| "1." | 2.67 | The effect of cisapride on gastro-oesophageal dysfunction in systemic sclerosis: a controlled manometric study. ( Amor, B; Chaussade, S; Couturier, D; Freitag, B; Gaudric, M; Guerre, J; Kahan, A; Menkes, CJ; Strauch, G, 1991) |
| "placebo in 12 patients with progressive systemic sclerosis and proven esophageal dysfunction as well as in 10 healthy volunteers in a double-blind, prospective trial." | 2.67 | [Effect of cisapride on esophageal motility in healthy probands and patients with progressive systemic scleroderma]. ( Caspary, WF; Wehrmann, T, 1990) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (25.00) | 18.7374 |
| 1990's | 4 (50.00) | 18.2507 |
| 2000's | 2 (25.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Wang, SJ | 2 |
| Lan, JL | 2 |
| Chen, DY | 2 |
| Chen, YH | 2 |
| Hsieh, TY | 2 |
| Lin, WY | 2 |
| Folwaczny, C | 1 |
| Läritz, M | 1 |
| Meurer, M | 1 |
| Endres, SP | 1 |
| König, A | 1 |
| Schindlbeck, N | 1 |
| La, JL | 1 |
| Limburg, AJ | 1 |
| Smit, AJ | 1 |
| Kleibeuker, JH | 1 |
| Kahan, A | 1 |
| Chaussade, S | 1 |
| Gaudric, M | 1 |
| Freitag, B | 1 |
| Amor, B | 1 |
| Menkes, CJ | 1 |
| Strauch, G | 1 |
| Guerre, J | 1 |
| Couturier, D | 1 |
| Wehrmann, T | 1 |
| Caspary, WF | 1 |
| Horowitz, M | 1 |
| Maddern, GJ | 1 |
| Maddox, A | 1 |
| Wishart, J | 1 |
| Chatterton, BE | 1 |
| Shearman, DJ | 1 |
| Nishioka, T | 1 |
| Sekiguchi, T | 1 |
| Machida, M | 1 |
| Kusano, M | 1 |
| Kogure, M | 1 |
| Matsuzaki, T | 1 |
| Katoh, R | 1 |
| Horikoshi, T | 1 |
| Fukagawa, H | 1 |
| Tajima, H | 1 |
6 trials available for cisapride and Scleroderma, Systemic
| Article | Year |
|---|---|
Effects of cisapride on colonic transit in patients with progressive systemic sclerosis.
Topics: Adult; Aged; Cisapride; Colon; Constipation; Female; Gastrointestinal Agents; Gastrointestinal Trans | 2002 |
Effects of cisapride on oesophageal transit of solids in patients with progressive systemic sclerosis.
Topics: Administration, Oral; Adult; Aged; Cisapride; Cross-Over Studies; Double-Blind Method; Esophageal Mo | 2002 |
Effects of cisapride on the esophageal motor function of patients with progressive systemic sclerosis or mixed connective tissue disease.
Topics: Adult; Aged; Cisapride; Double-Blind Method; Esophagogastric Junction; Esophagus; Female; Humans; Ma | 1991 |
The effect of cisapride on gastro-oesophageal dysfunction in systemic sclerosis: a controlled manometric study.
Topics: Cisapride; Double-Blind Method; Esophagogastric Junction; Female; Gastric Fundus; Gastrointestinal M | 1991 |
[Effect of cisapride on esophageal motility in healthy probands and patients with progressive systemic scleroderma].
Topics: Adult; Cisapride; Double-Blind Method; Esophageal Motility Disorders; Esophagus; Female; Humans; Mal | 1990 |
Effects of cisapride on gastric and esophageal emptying in progressive systemic sclerosis.
Topics: Adult; Cisapride; Esophagus; Female; Gastric Emptying; Gastrointestinal Diseases; Humans; Male; Midd | 1987 |
2 other studies available for cisapride and Scleroderma, Systemic
| Article | Year |
|---|---|
[Effects of various prokinetic drugs on gastrointestinal transit times in patients with progressive systemic scleroderma].
Topics: Aged; Cisapride; Dose-Response Relationship, Drug; Drug Administration Schedule; Erythromycin; Femal | 1997 |
[Effects of cisapride on lower esophageal sphincter pressure and gastroduodenal motor activity in man].
Topics: Adolescent; Adult; Aged; Cisapride; Duodenum; Electromyography; Esophagitis, Peptic; Esophagogastric | 1986 |