cisapride has been researched along with Recrudescence in 20 studies
Cisapride: A substituted benzamide used for its prokinetic properties. It is used in the management of gastroesophageal reflux disease, functional dyspepsia, and other disorders associated with impaired gastrointestinal motility. (Martindale The Extra Pharmacopoeia, 31st ed)
cisapride : The amide resulting from formal condensation of 4-amino-5-chloro-2-methoxybenzoic acid with cis-1-[3-(4-fluorophenoxy)propyl]-3-methoxypiperidin-4-amine. It has been used (as its monohydrate or as its tartrate) for the treatment of gastro-oesophageal reflux disease and for non-ulcer dyspepsia, but its propensity to cause cardiac arrhythmias resulted in its complete withdrawal from many countries, including the U.K., and restrictions on its use elsewhere.
Excerpt | Relevance | Reference |
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"Cisapride and ranitidine improved the symptoms of diffuse epigastric pain, postprandial epigastric fullness, epigastric distension, belching, heartburn, regurgitation, and nausea when compared with baseline." | 9.08 | Cisapride compared with ranitidine in the treatment of functional dyspepsia. ( Carvalhinhos, A; Fidalgo, P; Freire, A; Matos, L, 1995) |
"In a single centre double blind study of 66 patients, the value of cisapride (10 mg twice daily) was compared with placebo in the prevention of duodenal ulcer relapse." | 9.07 | Acid, motility, and ulcers: a comparison of cisapride with placebo in the prevention of duodenal ulcer relapse. ( Johnson, AG; Kerrigan, DD; Read, NW; Taylor, ME, 1993) |
"In a double-blind, placebo-controlled, crossover trial, we investigated the effects of the prokinetic drug cisapride in patients with cystic fibrosis and chronic recurrent distal intestinal obstruction syndrome (DIOS)." | 9.06 | Effects of cisapride in patients with cystic fibrosis and distal intestinal obstruction syndrome. ( Corey, M; Durie, PR; Ellis, L; Koletzko, S; Spino, M; Stringer, DA, 1990) |
"Cisapride has well-documented prokinetic effects and may be well suited for long-term therapy of GORD, but its effectiveness in purely symptomatic treatment is unknown." | 6.68 | The effect of cisapride in maintaining symptomatic remission in patients with gastro-oesophageal reflux disease. ( Carling, L; Hatlebakk, JG; Johnsson, F; Thøgersen, T; Vilien, M; Wetterhus, S, 1997) |
"Cisapride and ranitidine improved the symptoms of diffuse epigastric pain, postprandial epigastric fullness, epigastric distension, belching, heartburn, regurgitation, and nausea when compared with baseline." | 5.08 | Cisapride compared with ranitidine in the treatment of functional dyspepsia. ( Carvalhinhos, A; Fidalgo, P; Freire, A; Matos, L, 1995) |
"In a single centre double blind study of 66 patients, the value of cisapride (10 mg twice daily) was compared with placebo in the prevention of duodenal ulcer relapse." | 5.07 | Acid, motility, and ulcers: a comparison of cisapride with placebo in the prevention of duodenal ulcer relapse. ( Johnson, AG; Kerrigan, DD; Read, NW; Taylor, ME, 1993) |
"In a Dutch general practice trial conducted in 599 patients with symptoms of dyspepsia, the response to 5 mg cisapride three times daily was rated excellent or good in 61% of patients at week 2." | 5.07 | Factors affecting short- and long-term outcome of a short therapeutic trial with cisapride in dyspeptic patients. ( Hazelhoff, B; Heyse, PM; Rambaldo, R, 1993) |
"In a double-blind, placebo-controlled, crossover trial, we investigated the effects of the prokinetic drug cisapride in patients with cystic fibrosis and chronic recurrent distal intestinal obstruction syndrome (DIOS)." | 5.06 | Effects of cisapride in patients with cystic fibrosis and distal intestinal obstruction syndrome. ( Corey, M; Durie, PR; Ellis, L; Koletzko, S; Spino, M; Stringer, DA, 1990) |
"The total effective rate and recurrence rate of the treated group were superior to those of the control group significantly (P < 0." | 2.71 | Effect of modified Sinisan on anorectal manometry of the constipation predominant type of irritable bowel syndrome. ( Chen, G; Ding, SQ; Ha, NL; Ye, H; Yu, SP, 2005) |
"Cisapride was related to a temporary relief of the symptoms in 10/12 children." | 2.69 | Effect of prokinetics in children with recurrent nocturnal retrosternal pain. ( de Pont, S; Hegar, B; Vandemaele, K; Vandenplas, Y, 1998) |
"Omeprazole was significantly more effective than cisapride (P = 0." | 2.68 | A comparison of five maintenance therapies for reflux esophagitis. ( Badalamenti, S; Battaglia, G; Di Mario, F; Leandro, G; Mela, GS; Pantalena, M; Pilotto, A; Savarino, V; Termini, R; Vigneri, S, 1995) |
"Cisapride has well-documented prokinetic effects and may be well suited for long-term therapy of GORD, but its effectiveness in purely symptomatic treatment is unknown." | 2.68 | The effect of cisapride in maintaining symptomatic remission in patients with gastro-oesophageal reflux disease. ( Carling, L; Hatlebakk, JG; Johnsson, F; Thøgersen, T; Vilien, M; Wetterhus, S, 1997) |
"Cholelithiasis affects 10-15% of the adult population in Western society, and about 75% of gallstones are of cholesterol type." | 2.39 | Cholesterol gallstone formation in man and potential treatments of the gallbladder motility defect. ( Palasciano, G; Portincasa, P; Stolk, MF; van Berge-Henegouwen, GP; van Erpecum, KJ, 1995) |
"Recurrent vomiting is one of many functional conditions for which it is difficult to find an explanation and to treat." | 1.33 | A case report on a patient suffering from recurrent vomiting episodes, whose condition improved markedly during pregnancy and breast feeding. ( Ohlsson, B, 2006) |
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 0 (0.00) | 18.7374 |
1990's | 17 (85.00) | 18.2507 |
2000's | 3 (15.00) | 29.6817 |
2010's | 0 (0.00) | 24.3611 |
2020's | 0 (0.00) | 2.80 |
Authors | Studies |
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Schimpl, G | 1 |
Uray, E | 1 |
Ratschek, M | 1 |
Höllwarth, ME | 1 |
Yu, SP | 1 |
Ye, H | 1 |
Ha, NL | 1 |
Ding, SQ | 1 |
Chen, G | 1 |
Ohlsson, B | 1 |
Vigneri, S | 1 |
Termini, R | 1 |
Leandro, G | 1 |
Badalamenti, S | 1 |
Pantalena, M | 1 |
Savarino, V | 1 |
Di Mario, F | 1 |
Battaglia, G | 1 |
Mela, GS | 1 |
Pilotto, A | 1 |
Carvalhinhos, A | 1 |
Fidalgo, P | 1 |
Freire, A | 1 |
Matos, L | 1 |
Kimmig, JM | 1 |
Kerrigan, DD | 1 |
Taylor, ME | 1 |
Read, NW | 1 |
Johnson, AG | 1 |
Blum, AL | 1 |
Adami, B | 1 |
Bouzo, MH | 1 |
Brandstätter, G | 1 |
Fumagalli, I | 1 |
Galmiche, JP | 1 |
Hebbeln, H | 1 |
Hentschel, E | 1 |
Hüttemann, W | 1 |
SChütz, E | 1 |
Heyse, PM | 1 |
Rambaldo, R | 1 |
Hazelhoff, B | 1 |
Tytgat, GN | 2 |
Portincasa, P | 1 |
Stolk, MF | 1 |
van Erpecum, KJ | 1 |
Palasciano, G | 1 |
van Berge-Henegouwen, GP | 1 |
Hudziak, H | 1 |
Brignoli, R | 1 |
Watkins, P | 1 |
Halter, F | 1 |
Hatlebakk, JG | 1 |
Johnsson, F | 1 |
Vilien, M | 1 |
Carling, L | 2 |
Wetterhus, S | 1 |
Thøgersen, T | 1 |
Heading, RC | 1 |
Baldi, F | 1 |
Holloway, RH | 1 |
Janssens, J | 1 |
Jian, R | 1 |
McCallum, RW | 1 |
Richter, JE | 1 |
Scarpignato, C | 1 |
Sontag, SJ | 1 |
Wienbeck, M | 1 |
Hegar, B | 1 |
de Pont, S | 1 |
Vandemaele, K | 1 |
Vandenplas, Y | 1 |
Mukhopadhyay, K | 1 |
Narang, A | 1 |
Kumar, P | 1 |
Chakraborty, S | 1 |
Mittal, BR | 1 |
Anker Hansen, OJ | 1 |
de Groot, GH | 1 |
Geldof, H | 1 |
Glise, H | 1 |
Efskind, P | 1 |
Elsborg, L | 1 |
Karvonen, AL | 1 |
Ohlin, B | 1 |
Toussaint, J | 1 |
Gossuin, A | 1 |
Deruyttere, M | 1 |
Hublé, F | 1 |
Devis, G | 1 |
Koletzko, S | 1 |
Corey, M | 1 |
Ellis, L | 1 |
Spino, M | 1 |
Stringer, DA | 1 |
Durie, PR | 1 |
2 reviews available for cisapride and Recrudescence
Article | Year |
---|---|
Cholesterol gallstone formation in man and potential treatments of the gallbladder motility defect.
Topics: Adult; Animals; Anti-Bacterial Agents; Cholelithiasis; Cholesterol; Cisapride; Crystallization; Fema | 1995 |
[Treatment of stomach ulcer].
Topics: Anti-Ulcer Agents; Cisapride; Drug Resistance; Helicobacter Infections; Histamine H2 Antagonists; Hu | 1996 |
13 trials available for cisapride and Recrudescence
Article | Year |
---|---|
Effect of modified Sinisan on anorectal manometry of the constipation predominant type of irritable bowel syndrome.
Topics: Adult; Aged; Anal Canal; Cisapride; Constipation; Female; Follow-Up Studies; Gastrointestinal Agents | 2005 |
A comparison of five maintenance therapies for reflux esophagitis.
Topics: Adult; Anti-Ulcer Agents; Cisapride; Disease-Free Survival; Drug Therapy, Combination; Esophagitis, | 1995 |
Cisapride compared with ranitidine in the treatment of functional dyspepsia.
Topics: Adult; Antacids; Anti-Ulcer Agents; Cisapride; Double-Blind Method; Dyspepsia; Eructation; Female; F | 1995 |
Treatment and prevention of relapse of mild oesophagitis with omeprazole and cisapride: comparison of two strategies.
Topics: Adult; Aged; Cisapride; Drug Administration Schedule; Drug Therapy, Combination; Esophagitis, Peptic | 1995 |
Acid, motility, and ulcers: a comparison of cisapride with placebo in the prevention of duodenal ulcer relapse.
Topics: Adolescent; Adult; Aged; Anti-Ulcer Agents; Cisapride; Confidence Intervals; Double-Blind Method; Du | 1993 |
Effect of cisapride on relapse of esophagitis. A multinational, placebo-controlled trial in patients healed with an antisecretory drug. The Italian Eurocis Trialists.
Topics: Cisapride; Double-Blind Method; Drug Administration Schedule; Esophagitis, Peptic; Esophagoscopy; Fe | 1993 |
Factors affecting short- and long-term outcome of a short therapeutic trial with cisapride in dyspeptic patients.
Topics: Adult; Age Factors; Aged; Cisapride; Dyspepsia; Female; Follow-Up Studies; Gastrointestinal Motility | 1993 |
The Omega-Project--a comparison of two diagnostic strategies for risk- and cost-oriented management of dyspepsia.
Topics: Adult; Cisapride; Costs and Cost Analysis; Domperidone; Dopamine Antagonists; Double-Blind Method; D | 1997 |
The effect of cisapride in maintaining symptomatic remission in patients with gastro-oesophageal reflux disease.
Topics: Abdominal Pain; Cisapride; Constipation; Diarrhea; Drug Administration Schedule; Endoscopy; Esophagi | 1997 |
Effect of prokinetics in children with recurrent nocturnal retrosternal pain.
Topics: Child; Cisapride; Female; Gastroesophageal Reflux; Gastrointestinal Agents; Humans; Hydrogen-Ion Con | 1998 |
Effect of cisapride on relapse of reflux oesophagitis, healed with an antisecretory drug.
Topics: Anti-Ulcer Agents; Cisapride; Double-Blind Method; Esophagitis, Peptic; Female; Humans; Male; Middle | 1992 |
Healing and prevention of relapse of reflux oesophagitis by cisapride.
Topics: Adolescent; Adult; Aged; Cisapride; Double-Blind Method; Esophagitis, Peptic; Esophagus; Female; Hum | 1991 |
Effects of cisapride in patients with cystic fibrosis and distal intestinal obstruction syndrome.
Topics: Adolescent; Adult; Chronic Disease; Cisapride; Cystic Fibrosis; Double-Blind Method; Female; Humans; | 1990 |
5 other studies available for cisapride and Recrudescence
Article | Year |
---|---|
Constipation and intestinal neuronal dysplasia type B: a clinical follow-up study.
Topics: Age of Onset; Cathartics; Child, Preschool; Cisapride; Constipation; Defecation; Female; Follow-Up S | 2004 |
A case report on a patient suffering from recurrent vomiting episodes, whose condition improved markedly during pregnancy and breast feeding.
Topics: Acetylcholine; Adult; Breast Feeding; Cisapride; Endoscopy, Digestive System; Female; Gastric Emptyi | 2006 |
The clinical use of cisapride in gastro-oesophageal reflux disease, with particular focus on the long-term treatment aspects.
Topics: Anti-Ulcer Agents; Cisapride; Gastroesophageal Reflux; Histamine H2 Antagonists; Humans; Piperidines | 1995 |
Prokinetics in the treatment of gastro-oesophageal reflux disease. International symposium. Paris, France, 5 September 1996.
Topics: Barrett Esophagus; Bethanechol; Cisapride; Gastric Emptying; Gastroesophageal Reflux; Gastrointestin | 1998 |
Gastroesophageal reflux and pulmonary complication in a neonate.
Topics: Antiemetics; Apnea; Cisapride; Follow-Up Studies; Gastroesophageal Reflux; Gastrointestinal Agents; | 1998 |