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cisapride and Recrudescence

cisapride has been researched along with Recrudescence in 20 studies

Cisapride: A substituted benzamide used for its prokinetic properties. It is used in the management of gastroesophageal reflux disease, functional dyspepsia, and other disorders associated with impaired gastrointestinal motility. (Martindale The Extra Pharmacopoeia, 31st ed)
cisapride : The amide resulting from formal condensation of 4-amino-5-chloro-2-methoxybenzoic acid with cis-1-[3-(4-fluorophenoxy)propyl]-3-methoxypiperidin-4-amine. It has been used (as its monohydrate or as its tartrate) for the treatment of gastro-oesophageal reflux disease and for non-ulcer dyspepsia, but its propensity to cause cardiac arrhythmias resulted in its complete withdrawal from many countries, including the U.K., and restrictions on its use elsewhere.

Research Excerpts

ExcerptRelevanceReference
"Cisapride and ranitidine improved the symptoms of diffuse epigastric pain, postprandial epigastric fullness, epigastric distension, belching, heartburn, regurgitation, and nausea when compared with baseline."9.08Cisapride compared with ranitidine in the treatment of functional dyspepsia. ( Carvalhinhos, A; Fidalgo, P; Freire, A; Matos, L, 1995)
"In a single centre double blind study of 66 patients, the value of cisapride (10 mg twice daily) was compared with placebo in the prevention of duodenal ulcer relapse."9.07Acid, motility, and ulcers: a comparison of cisapride with placebo in the prevention of duodenal ulcer relapse. ( Johnson, AG; Kerrigan, DD; Read, NW; Taylor, ME, 1993)
"In a double-blind, placebo-controlled, crossover trial, we investigated the effects of the prokinetic drug cisapride in patients with cystic fibrosis and chronic recurrent distal intestinal obstruction syndrome (DIOS)."9.06Effects of cisapride in patients with cystic fibrosis and distal intestinal obstruction syndrome. ( Corey, M; Durie, PR; Ellis, L; Koletzko, S; Spino, M; Stringer, DA, 1990)
"Cisapride has well-documented prokinetic effects and may be well suited for long-term therapy of GORD, but its effectiveness in purely symptomatic treatment is unknown."6.68The effect of cisapride in maintaining symptomatic remission in patients with gastro-oesophageal reflux disease. ( Carling, L; Hatlebakk, JG; Johnsson, F; Thøgersen, T; Vilien, M; Wetterhus, S, 1997)
"Cisapride and ranitidine improved the symptoms of diffuse epigastric pain, postprandial epigastric fullness, epigastric distension, belching, heartburn, regurgitation, and nausea when compared with baseline."5.08Cisapride compared with ranitidine in the treatment of functional dyspepsia. ( Carvalhinhos, A; Fidalgo, P; Freire, A; Matos, L, 1995)
"In a single centre double blind study of 66 patients, the value of cisapride (10 mg twice daily) was compared with placebo in the prevention of duodenal ulcer relapse."5.07Acid, motility, and ulcers: a comparison of cisapride with placebo in the prevention of duodenal ulcer relapse. ( Johnson, AG; Kerrigan, DD; Read, NW; Taylor, ME, 1993)
"In a Dutch general practice trial conducted in 599 patients with symptoms of dyspepsia, the response to 5 mg cisapride three times daily was rated excellent or good in 61% of patients at week 2."5.07Factors affecting short- and long-term outcome of a short therapeutic trial with cisapride in dyspeptic patients. ( Hazelhoff, B; Heyse, PM; Rambaldo, R, 1993)
"In a double-blind, placebo-controlled, crossover trial, we investigated the effects of the prokinetic drug cisapride in patients with cystic fibrosis and chronic recurrent distal intestinal obstruction syndrome (DIOS)."5.06Effects of cisapride in patients with cystic fibrosis and distal intestinal obstruction syndrome. ( Corey, M; Durie, PR; Ellis, L; Koletzko, S; Spino, M; Stringer, DA, 1990)
"The total effective rate and recurrence rate of the treated group were superior to those of the control group significantly (P < 0."2.71Effect of modified Sinisan on anorectal manometry of the constipation predominant type of irritable bowel syndrome. ( Chen, G; Ding, SQ; Ha, NL; Ye, H; Yu, SP, 2005)
"Cisapride was related to a temporary relief of the symptoms in 10/12 children."2.69Effect of prokinetics in children with recurrent nocturnal retrosternal pain. ( de Pont, S; Hegar, B; Vandemaele, K; Vandenplas, Y, 1998)
"Omeprazole was significantly more effective than cisapride (P = 0."2.68A comparison of five maintenance therapies for reflux esophagitis. ( Badalamenti, S; Battaglia, G; Di Mario, F; Leandro, G; Mela, GS; Pantalena, M; Pilotto, A; Savarino, V; Termini, R; Vigneri, S, 1995)
"Cisapride has well-documented prokinetic effects and may be well suited for long-term therapy of GORD, but its effectiveness in purely symptomatic treatment is unknown."2.68The effect of cisapride in maintaining symptomatic remission in patients with gastro-oesophageal reflux disease. ( Carling, L; Hatlebakk, JG; Johnsson, F; Thøgersen, T; Vilien, M; Wetterhus, S, 1997)
"Cholelithiasis affects 10-15% of the adult population in Western society, and about 75% of gallstones are of cholesterol type."2.39Cholesterol gallstone formation in man and potential treatments of the gallbladder motility defect. ( Palasciano, G; Portincasa, P; Stolk, MF; van Berge-Henegouwen, GP; van Erpecum, KJ, 1995)
"Recurrent vomiting is one of many functional conditions for which it is difficult to find an explanation and to treat."1.33A case report on a patient suffering from recurrent vomiting episodes, whose condition improved markedly during pregnancy and breast feeding. ( Ohlsson, B, 2006)

Research

Studies (20)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's17 (85.00)18.2507
2000's3 (15.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Schimpl, G1
Uray, E1
Ratschek, M1
Höllwarth, ME1
Yu, SP1
Ye, H1
Ha, NL1
Ding, SQ1
Chen, G1
Ohlsson, B1
Vigneri, S1
Termini, R1
Leandro, G1
Badalamenti, S1
Pantalena, M1
Savarino, V1
Di Mario, F1
Battaglia, G1
Mela, GS1
Pilotto, A1
Carvalhinhos, A1
Fidalgo, P1
Freire, A1
Matos, L1
Kimmig, JM1
Kerrigan, DD1
Taylor, ME1
Read, NW1
Johnson, AG1
Blum, AL1
Adami, B1
Bouzo, MH1
Brandstätter, G1
Fumagalli, I1
Galmiche, JP1
Hebbeln, H1
Hentschel, E1
Hüttemann, W1
SChütz, E1
Heyse, PM1
Rambaldo, R1
Hazelhoff, B1
Tytgat, GN2
Portincasa, P1
Stolk, MF1
van Erpecum, KJ1
Palasciano, G1
van Berge-Henegouwen, GP1
Hudziak, H1
Brignoli, R1
Watkins, P1
Halter, F1
Hatlebakk, JG1
Johnsson, F1
Vilien, M1
Carling, L2
Wetterhus, S1
Thøgersen, T1
Heading, RC1
Baldi, F1
Holloway, RH1
Janssens, J1
Jian, R1
McCallum, RW1
Richter, JE1
Scarpignato, C1
Sontag, SJ1
Wienbeck, M1
Hegar, B1
de Pont, S1
Vandemaele, K1
Vandenplas, Y1
Mukhopadhyay, K1
Narang, A1
Kumar, P1
Chakraborty, S1
Mittal, BR1
Anker Hansen, OJ1
de Groot, GH1
Geldof, H1
Glise, H1
Efskind, P1
Elsborg, L1
Karvonen, AL1
Ohlin, B1
Toussaint, J1
Gossuin, A1
Deruyttere, M1
Hublé, F1
Devis, G1
Koletzko, S1
Corey, M1
Ellis, L1
Spino, M1
Stringer, DA1
Durie, PR1

Reviews

2 reviews available for cisapride and Recrudescence

ArticleYear
Cholesterol gallstone formation in man and potential treatments of the gallbladder motility defect.
    Scandinavian journal of gastroenterology. Supplement, 1995, Volume: 212

    Topics: Adult; Animals; Anti-Bacterial Agents; Cholelithiasis; Cholesterol; Cisapride; Crystallization; Fema

1995
[Treatment of stomach ulcer].
    Gastroenterologie clinique et biologique, 1996, Volume: 20, Issue:1 Pt 2

    Topics: Anti-Ulcer Agents; Cisapride; Drug Resistance; Helicobacter Infections; Histamine H2 Antagonists; Hu

1996

Trials

13 trials available for cisapride and Recrudescence

ArticleYear
Effect of modified Sinisan on anorectal manometry of the constipation predominant type of irritable bowel syndrome.
    Chinese journal of integrative medicine, 2005, Volume: 11, Issue:1

    Topics: Adult; Aged; Anal Canal; Cisapride; Constipation; Female; Follow-Up Studies; Gastrointestinal Agents

2005
A comparison of five maintenance therapies for reflux esophagitis.
    The New England journal of medicine, 1995, Oct-26, Volume: 333, Issue:17

    Topics: Adult; Anti-Ulcer Agents; Cisapride; Disease-Free Survival; Drug Therapy, Combination; Esophagitis,

1995
Cisapride compared with ranitidine in the treatment of functional dyspepsia.
    European journal of gastroenterology & hepatology, 1995, Volume: 7, Issue:5

    Topics: Adult; Antacids; Anti-Ulcer Agents; Cisapride; Double-Blind Method; Dyspepsia; Eructation; Female; F

1995
Treatment and prevention of relapse of mild oesophagitis with omeprazole and cisapride: comparison of two strategies.
    Alimentary pharmacology & therapeutics, 1995, Volume: 9, Issue:3

    Topics: Adult; Aged; Cisapride; Drug Administration Schedule; Drug Therapy, Combination; Esophagitis, Peptic

1995
Acid, motility, and ulcers: a comparison of cisapride with placebo in the prevention of duodenal ulcer relapse.
    Gut, 1993, Volume: 34, Issue:8

    Topics: Adolescent; Adult; Aged; Anti-Ulcer Agents; Cisapride; Confidence Intervals; Double-Blind Method; Du

1993
Effect of cisapride on relapse of esophagitis. A multinational, placebo-controlled trial in patients healed with an antisecretory drug. The Italian Eurocis Trialists.
    Digestive diseases and sciences, 1993, Volume: 38, Issue:3

    Topics: Cisapride; Double-Blind Method; Drug Administration Schedule; Esophagitis, Peptic; Esophagoscopy; Fe

1993
Factors affecting short- and long-term outcome of a short therapeutic trial with cisapride in dyspeptic patients.
    Scandinavian journal of gastroenterology. Supplement, 1993, Volume: 195

    Topics: Adult; Age Factors; Aged; Cisapride; Dyspepsia; Female; Follow-Up Studies; Gastrointestinal Motility

1993
The Omega-Project--a comparison of two diagnostic strategies for risk- and cost-oriented management of dyspepsia.
    European journal of gastroenterology & hepatology, 1997, Volume: 9, Issue:4

    Topics: Adult; Cisapride; Costs and Cost Analysis; Domperidone; Dopamine Antagonists; Double-Blind Method; D

1997
The effect of cisapride in maintaining symptomatic remission in patients with gastro-oesophageal reflux disease.
    Scandinavian journal of gastroenterology, 1997, Volume: 32, Issue:11

    Topics: Abdominal Pain; Cisapride; Constipation; Diarrhea; Drug Administration Schedule; Endoscopy; Esophagi

1997
Effect of prokinetics in children with recurrent nocturnal retrosternal pain.
    European journal of gastroenterology & hepatology, 1998, Volume: 10, Issue:7

    Topics: Child; Cisapride; Female; Gastroesophageal Reflux; Gastrointestinal Agents; Humans; Hydrogen-Ion Con

1998
Effect of cisapride on relapse of reflux oesophagitis, healed with an antisecretory drug.
    Scandinavian journal of gastroenterology, 1992, Volume: 27, Issue:3

    Topics: Anti-Ulcer Agents; Cisapride; Double-Blind Method; Esophagitis, Peptic; Female; Humans; Male; Middle

1992
Healing and prevention of relapse of reflux oesophagitis by cisapride.
    Gut, 1991, Volume: 32, Issue:11

    Topics: Adolescent; Adult; Aged; Cisapride; Double-Blind Method; Esophagitis, Peptic; Esophagus; Female; Hum

1991
Effects of cisapride in patients with cystic fibrosis and distal intestinal obstruction syndrome.
    The Journal of pediatrics, 1990, Volume: 117, Issue:5

    Topics: Adolescent; Adult; Chronic Disease; Cisapride; Cystic Fibrosis; Double-Blind Method; Female; Humans;

1990

Other Studies

5 other studies available for cisapride and Recrudescence

ArticleYear
Constipation and intestinal neuronal dysplasia type B: a clinical follow-up study.
    Journal of pediatric gastroenterology and nutrition, 2004, Volume: 38, Issue:3

    Topics: Age of Onset; Cathartics; Child, Preschool; Cisapride; Constipation; Defecation; Female; Follow-Up S

2004
A case report on a patient suffering from recurrent vomiting episodes, whose condition improved markedly during pregnancy and breast feeding.
    BMC gastroenterology, 2006, Oct-21, Volume: 6

    Topics: Acetylcholine; Adult; Breast Feeding; Cisapride; Endoscopy, Digestive System; Female; Gastric Emptyi

2006
The clinical use of cisapride in gastro-oesophageal reflux disease, with particular focus on the long-term treatment aspects.
    Scandinavian journal of gastroenterology. Supplement, 1995, Volume: 211

    Topics: Anti-Ulcer Agents; Cisapride; Gastroesophageal Reflux; Histamine H2 Antagonists; Humans; Piperidines

1995
Prokinetics in the treatment of gastro-oesophageal reflux disease. International symposium. Paris, France, 5 September 1996.
    European journal of gastroenterology & hepatology, 1998, Volume: 10, Issue:1

    Topics: Barrett Esophagus; Bethanechol; Cisapride; Gastric Emptying; Gastroesophageal Reflux; Gastrointestin

1998
Gastroesophageal reflux and pulmonary complication in a neonate.
    Indian pediatrics, 1998, Volume: 35, Issue:7

    Topics: Antiemetics; Apnea; Cisapride; Follow-Up Studies; Gastroesophageal Reflux; Gastrointestinal Agents;

1998