cisapride has been researched along with Pregnancy in 8 studies
Cisapride: A substituted benzamide used for its prokinetic properties. It is used in the management of gastroesophageal reflux disease, functional dyspepsia, and other disorders associated with impaired gastrointestinal motility. (Martindale The Extra Pharmacopoeia, 31st ed)
cisapride : The amide resulting from formal condensation of 4-amino-5-chloro-2-methoxybenzoic acid with cis-1-[3-(4-fluorophenoxy)propyl]-3-methoxypiperidin-4-amine. It has been used (as its monohydrate or as its tartrate) for the treatment of gastro-oesophageal reflux disease and for non-ulcer dyspepsia, but its propensity to cause cardiac arrhythmias resulted in its complete withdrawal from many countries, including the U.K., and restrictions on its use elsewhere.
Pregnancy: The status during which female mammals carry their developing young (EMBRYOS or FETUSES) in utero before birth, beginning from FERTILIZATION to BIRTH.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The objective of this study was to compare the neonatal postoperative course and morbidity for patients with gastroschisis who received cisapride with those who did not receive cisapride." | 7.70 | Cisapride and caesarean section: their role in babies with gastroschisis. ( Duffy, B; Kumar, RK; Shi, EC, 1999) |
| "The objective of this prospective multicenter study was to determine whether cisapride is associated with increased risk of malformations, spontaneous abortions, or decreased birthweight when used during pregnancy." | 7.69 | Cisapride use during human pregnancy: a prospective, controlled multicenter study. ( Addis, A; Bailey, B; Bonati, M; Conover, B; De Souza, CF; Garbis, H; Koren, G; Lau, M; Lee, A; Mastroiacovo, P; Matsui, D; Mazzone, T; Paolini, C; Sanghvi, K; Schechtman, AS; Val, T, 1997) |
| "The objective of this study was to compare the neonatal postoperative course and morbidity for patients with gastroschisis who received cisapride with those who did not receive cisapride." | 3.70 | Cisapride and caesarean section: their role in babies with gastroschisis. ( Duffy, B; Kumar, RK; Shi, EC, 1999) |
| "The objective of this prospective multicenter study was to determine whether cisapride is associated with increased risk of malformations, spontaneous abortions, or decreased birthweight when used during pregnancy." | 3.69 | Cisapride use during human pregnancy: a prospective, controlled multicenter study. ( Addis, A; Bailey, B; Bonati, M; Conover, B; De Souza, CF; Garbis, H; Koren, G; Lau, M; Lee, A; Mastroiacovo, P; Matsui, D; Mazzone, T; Paolini, C; Sanghvi, K; Schechtman, AS; Val, T, 1997) |
| " Instead, single dosing on specific days is proposed to be a better way to characterize the teratogenic potential of Ikr blocking drugs." | 2.44 | Embryonic cardiac arrhythmia and generation of reactive oxygen species: common teratogenic mechanism for IKr blocking drugs. ( Danielsson, BR; Danielsson, C; Nilsson, MF, 2007) |
| "Heartburn is a normal consequence of pregnancy." | 2.43 | Review article: the management of heartburn in pregnancy. ( Richter, JE, 2005) |
| "Recurrent vomiting is one of many functional conditions for which it is difficult to find an explanation and to treat." | 1.33 | A case report on a patient suffering from recurrent vomiting episodes, whose condition improved markedly during pregnancy and breast feeding. ( Ohlsson, B, 2006) |
| " The terminal plasma half-life of cisapride was about 1-2 h in the rat and about 4-10 h in the rabbit and dog." | 1.27 | Pharmacokinetics and tissue distribution of the new gastrokinetic agent cisapride in rat, rabbit and dog. ( Geerts, R; Hendriks, R; Heykants, J; Michiels, M; Monbaliu, J; Woestenborghs, R, 1987) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (25.00) | 18.7374 |
| 1990's | 2 (25.00) | 18.2507 |
| 2000's | 4 (50.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Levenson, D | 1 |
| Richter, JE | 1 |
| Ohlsson, B | 1 |
| Danielsson, BR | 1 |
| Danielsson, C | 1 |
| Nilsson, MF | 1 |
| Bailey, B | 1 |
| Addis, A | 1 |
| Lee, A | 1 |
| Sanghvi, K | 1 |
| Mastroiacovo, P | 1 |
| Mazzone, T | 1 |
| Bonati, M | 1 |
| Paolini, C | 1 |
| Garbis, H | 1 |
| Val, T | 1 |
| De Souza, CF | 1 |
| Matsui, D | 1 |
| Schechtman, AS | 1 |
| Conover, B | 1 |
| Lau, M | 1 |
| Koren, G | 1 |
| Kumar, RK | 1 |
| Shi, EC | 1 |
| Duffy, B | 1 |
| Michiels, M | 1 |
| Monbaliu, J | 1 |
| Hendriks, R | 1 |
| Geerts, R | 1 |
| Woestenborghs, R | 1 |
| Heykants, J | 1 |
| Hofmeyr, GJ | 1 |
| Sonnendecker, EW | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Comparison of the Efficacy of Alginate-based Reflux Suppressant and Magnesium-aluminium Antacid Gel for Treatment of Heartburn in Pregnancy : A Randomized Double-Blind Controlled Trial[NCT02470117] | Phase 4 | 100 participants (Actual) | Interventional | 2015-06-30 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
2 reviews available for cisapride and Pregnancy
| Article | Year |
|---|---|
Review article: the management of heartburn in pregnancy.
Topics: Antacids; Anti-Ulcer Agents; Cisapride; Female; Gastroesophageal Reflux; Gastrointestinal Motility; | 2005 |
Embryonic cardiac arrhythmia and generation of reactive oxygen species: common teratogenic mechanism for IKr blocking drugs.
Topics: Abnormalities, Drug-Induced; Animals; Anti-Arrhythmia Agents; Anticonvulsants; Arrhythmias, Cardiac; | 2007 |
6 other studies available for cisapride and Pregnancy
| Article | Year |
|---|---|
The youngest children are too frequently subject to drug errors, study says.
Topics: Anti-Infective Agents; Antibodies, Monoclonal; Antiviral Agents; Child, Preschool; Cisapride; Female | 2002 |
A case report on a patient suffering from recurrent vomiting episodes, whose condition improved markedly during pregnancy and breast feeding.
Topics: Acetylcholine; Adult; Breast Feeding; Cisapride; Endoscopy, Digestive System; Female; Gastric Emptyi | 2006 |
Cisapride use during human pregnancy: a prospective, controlled multicenter study.
Topics: Abnormalities, Drug-Induced; Abortion, Spontaneous; Adult; Birth Weight; Case-Control Studies; Cisap | 1997 |
Cisapride and caesarean section: their role in babies with gastroschisis.
Topics: Australia; Cesarean Section; Cisapride; Comorbidity; Cryptorchidism; Female; Follow-Up Studies; Gast | 1999 |
Pharmacokinetics and tissue distribution of the new gastrokinetic agent cisapride in rat, rabbit and dog.
Topics: Animals; Autoradiography; Cisapride; Dogs; Female; Male; Milk; Piperidines; Placenta; Pregnancy; Rab | 1987 |
Secretion of the gastrokinetic agent cisapride in human milk.
Topics: Adult; Cisapride; Female; Humans; Milk, Human; Piperidines; Postpartum Period; Pregnancy | 1986 |